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Antigens in Medical News

Rapid Swine Flu Test Misses Many Infections

... and Mortality Weekly Report , CDC researchers tested three commercially available rapid influenza diagnostic tests that can identify influenza A or B antigens in about 15 minutes. Respiratory samples were used from 65 people known to have swine flu or seasonal flu. The tests were able to detect the H1N1 s...

GenVec Receives Grant for Malaria Vaccine Program

...Bruder, head of GenVec's malaria program. This grant, valued at approximately $600,000 over two years, will be used to identify new immunogenic antigens for malaria vaccine development. Using the funding from this grant, GenVec will be collaborating with the U.S. Naval Medical Research Center (NMRC) to...

Eleven Veterinary Students Win Top Awards at Morris Animal Foundation's Annual Research Competition

... Place for Wildlife, $1,500 Santiago Diaz, University of Florida D07ZO-607 : "Use of Elephant-Specific Monoclonal Antibodies and Recombinant antigens of Mycobacterium tuberculosis to Improve an ELISA Test for Elephants" IMPACT Award, $500 Ana Iris Mota Torres, University of Veracruz (Me...

Abbott Reports Strong Second Quarter Results; Confirms Double-Digit Earnings Growth Outlook for 2009

...biologic targets. Additionally, our proprietary DVD-Ig technology represents an innovative approach that can target multiple disease-causing antigens with a single biologic agent. This technology could lead to combination biologics for complex conditions such as cancer or rheumatoid arthritis, where...

Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models

...ity that leads to other fatal complications in people with the condition. In the study, one group of experimental mice was vaccinated with Sm (Smith antigens that are small nuclear ribonucleoproteins: snRNPs) lupus autoantigen in combination with IL-10 and another group vaccinated with the same antigen and ...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

...PA. This data demonstrates that vaccines utilizing its L.E.A.P.S. vaccine technology with specificity for particular Mycobacterium tuberculosis (TB) antigens can elicit immune responses that would be protective against tuberculosis and have the potential to treat swine and other H1N1 influenzas. The investi...
Antigens in Medical Technology

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

VIENNA, Va., June 5 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (NYSE AMEX: CVM ) announced today that its collaborators at the University of Hawaii reported on data at the annual American Society for Microbiology in Philadelphia, PA. This data demonstrates that vaccines utilizing its L.E.A...

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

...th metastatic melanoma whose disease had been minimized by other therapies. The study entitled "Phase II Trial of Dendritic Cells Loaded with antigens from Self-Renewing, Proliferating Autologous Tumor Cells as Patient-Specific Anti-Tumor Vaccines in Patients with Metastatic Melanoma," was published ...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

...ells to the GALT and promotes their maturation. This unique aspect of its function results in recruitment of dendritic cells that have captured tumor antigens while in the peripheral circulation. Following maturation, these dendritic cells activate Natural Killer (NK) and Natural Killer T-cells (NK-T) of th...

AlphaVax Announces Promising Results in Melanoma Studies

...-clinical studies conducted at MSKCC demonstrate the ability of AlphaVax's virus-like replicon vector particles (VRP) encoding melanoma-specific tumor antigens to reduce melanoma tumor burden in a state-of-the-art murine melanoma model. Jedd D. Wolchok, M.D., Ph.D., Lab Head and faculty member at MSKCC, ...

Trubion Pharmaceuticals, Inc. Announces Upcoming Presentation at the 2009 American Association of Cancer Research Annual Meeting

...nal domains from naturally occurring proteins. However, SCORPION therapeutics are multispecific therapeutics that are capable of targeting two or more antigens simultaneously. Trubion's SCORPION format provides the basis for development of single therapies that simultaneously inhibit multiple ligand/receptor ...

CEL-SCI Corporation Releases Letter to Shareholders

...e system acts in defending us against cancer. As opposed to other immunotherapies which are designed to target a single or limited number of specific antigens or molecules, Immune SIMULATORS are multi-targeted; they simultaneously cause a direct and targeted killing of the specific tumor cells and they activ...
Antigens in Medical Products

Lymphocyte IL-12 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-10 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-6 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-2 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IL-4 Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Lymphocyte IFN g Response to Antigens and/or Mitogens

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

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Antigens in Medical Definition

Artificial induction of immunity

...r ways in researching the immune system. A more contemporary approach for "boosting" the immune response of simpler immunogenic molecules (known as antigens ) is to conjugate the antigens. Conjugation is the attachment to the antigen of another substance which also generates an immune response, thus ampl...

Central tolerance

...tion of the cells generated are self-reactive (recognise the component self antigens of the host). In mammals the process occurs in the thymus (T cells) [2... (B cells), when maturing lymphocytes are exposed to self antigens. Self antigens are present in both organs due to endogenous expression within the organ an...

Heterophile

...ender-neutral term, like "heterosexual" in Canada and the United States. Medical Heterophile Antibodies are antibodies induced by external antigens (Heterophile Antigens) that nevertheless cross-react with self-antigens. For example antibodies against Group A Streptococcus cell walls can also reac...

Thymocyte

...Histology of the thymus showing the cortex and medulla Minute structure of thymus. The ability of T cells to recognise foreign antigens is mediated by the T cell receptor , which is a surface protein able to recognise short protein sequences ( peptides ) that are presented on MHC . D...
Antigens in Medical Dictionary

Tuberculin

...nvolves injecting a very small amount of a ... Tuberculin is a mixture of antigens obtained from the culture of M. tuberculosis. ... Hence, it is recomm...mon use today is purified protein ... The Mantoux skin test uses TB antigens called purified protein derivative (PPD) ... A tuberculin skin test i...

Transfusion

...This booklet provides information about blood transfusion for patients with ... transfusion unless the patient has developed antibodies to these antigens as ... Transfusion reaction is a problem that occurs after a patient ... Blood transfusion between incompatible groups (such as A+ to ... to a...

Rh factor

... The term Rhesus ( Rh ) blood group system refers to the 5 main Rhesus antigens as well as the many other less frequent Rhesus antigens. The terms Rhesus factor and Rh factor are equivalent and refer to the Rh D antigen on...

Intradermal

... of influenza ... The intradermal vaccination against influenza can produce certain serum antibody ... Intradermal administration of antigens is expected to facilitate their exposure ... Intradermal Water Blocks: A literature review is performed to the assess effectiveness of the most ...

Immunoglobulin

...ulin M Capture Assay for Serologic Confirmation of Early Lyme Disease: ... Immunoglobulin allotypes (Gm and Km) and their interactions with HLA antigens in ... determinant formed by both immunoglobulin constant and variable regions. ... Patient handout discusses the symptoms, causes, diagnosis, a...

Immunofluorescence

... Immunofluorescence is the labeling of antibodies or antigens with fluorescent dyes. This technique is often used to visualize the subcel...e antibodies chemically linked to a fluorescent dye to identify or quantify antigens in a ... immunofluorescence ... Double Immunofluorescence stain (Gi...
Antigens in Biological News

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

...s with metastatic melanoma whose disease had been minimized by other therapies. The study entitled "Phase II Trial of Dendritic Cells Loaded with antigens from Self-Renewing, Proliferating Autologous Tumor Cells as Patient-Specific Anti-Tumor Vaccines in Patients with Metastatic Melanoma," was published ...

The right messenger for a healthy immune response

...play fragments of pathogens, so-called antigens. Immune cells present these antigens on their surface and in this way communicate with one another: antigens are the "wanted posters" of the virus or the bacterium which has to be dest...

American Chemical Society's Weekly PressPac -- May 20, 2009

...and prevent the condition, the study says. ARTICLE #1 FOR IMMEDIATE RELEASE "Immunoproteomic Identification of Secretory and Subcellular Protein antigens and Functional Evaluation of the Secretome Fraction of Mycobacterium immunogenum, a Newly Recognized Species of the Mycobacterium chelonae Mycobac...

UTSA, Health Science Center collaborate with Merck & Co. to develop chlamydia vaccine

...ction, a vaccine composed of a select group of recombinant C. trachomatis antigens can successfully accelerate bacterial clearance, and importantly, preserve ... working hard with the Merck group to identify the most efficacious vaccine antigens for inducing anti-chlamydial immunity. They are also planning to apply thei...

Gutsy germs succumb to baby broccoli

... assess colonization by H. pylori bacteria and blood tests to judge the severity of inflammation in the stomach lining; in addition, they looked for antigens in stool samples to help determine the extent of the infections. "We know that a dose of a couple ounces a day of broccoli sprouts is enough to e...

Lombardi research: Monoclonal antibodies primed to become potent immune weapons against cancer

...s viruses and bacteria. Monoclonal antibodies are proteins crafted in a laboratory to recognize specific receptors, or antigens, on cancer cells; some antigens promote uncontrolled growth. These antibodies are designed to both attach to cancer receptors to inhibit their function and to alert and activate the ...
Antigens in Biological Technology

Antigen Discovery Inc. Awarded a SBIR Phase II Grant to Commercialize Novel Antigens for Serodiagnostic Products and Vaccine Development

IRVINE, Calif., July 3 /PRNewswire/ -- Antigen Discovery Inc. ("ADI", formerly ImmPORT Therapeutics Inc.), a leader in high throughput antigen/biomarker discovery using advanced genomics and proteomics tools, announced today that the Company was awarded a Phase II SBIR from the National Instit...

ImmunoVaccine Technologies Licenses Immunotope's Breast, Ovarian and Prostate Cancer Antigens

HALIFAX, NS, July 14 /PRNewswire/ - ImmunoVaccine Technologies Inc. (IVT), a vaccine development company, has entered into an agreement to exclusively license seven cancer antigens from Immunotope Inc., an antigen discovery company. These proprietary antigens specifically target breast, ovarian an...

GenVec Reports Second Quarter 2009 Financial Results

...o support the Company's malaria vaccine program. This grant, valued at approximately $600,000 over two years, will be used to identify new immunogenic antigens for malaria vaccine development. Other Developments GenVec strengthened its cash position by raising $6.0 million from a ...

ImmunoVaccine Technologies Partners With Scancell to Advance DNA Vaccine Delivery

...of liposomes, adjuvants and oil. DepoVax(TM) enhances the immunogenicity of antigens in general, and can be used to dramatically enhance the delivery of polynucleotide-based antigens and SiRNA to lymph nodes. IVT has proven its scale-up capabilities at a con...

DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD

...ietic cell transplantation. GVHD is an inflammatory disease initiated by T cells in the donor graft that recognize histocompatibility and other tissue antigens of the host, and is mediated by a variety of effector cells and inflammatory cytokines. GVHD presents in both acute and chronic forms. The symptoms of...

Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose

...nza, using a transient expression system which produces recombinant vaccine antigens in non-transgenic plants. This technology has potential to offer advantages...the first wave of a pandemic strikes and to supply large volumes of vaccine antigens to the world market. Additional information about Medicago is available at ...
Antigens in Biological Products

Mouse Anti-Dronpa Green CoralHue Monoclonal Antibody, Unconjugated, Clone 2F6 from MBL International

Description:... Anti-CoralHue Dronpa Green Monoclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Company:MBL International

Rabbit Anti-LC3 Polyclonal Antibody, Unconjugated from MBL International

Description:... Anti-LC3 Polyclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Company:MBL International

PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (10X) from Lab Vision

Description:...maldehyde fixation impairs or totally destroys the immunoreactivity of many antigens and epitopes. The negative effect of formaldehyde fixation can be reversed...iques have been recently introduced to improve the immunoreactivity of many antigens in formaldehyde fixed tissues. Heat-Induced Epitope Retrieval (HIER) in EDT...
Company:Lab Vision

PT ModuleTM Deparaffinization and Heat-Induced Epitope Retrieval Solution (100X) from Lab Vision

Description:...maldehyde fixation impairs or totally destroys the immunoreactivity of many antigens and epitopes. The negative effect of formaldehyde fixation can be reversed...iques have been recently introduced to improve the immunoreactivity of many antigens in formaldehyde fixed tissues. Heat-Induced Epitope Retrieval (HIER) in EDT...
Company:Lab Vision

Complete Adjuvant from Santa Cruz Biotechnology, Inc.

Description:...injections; Incomplete Freund's adjuvant is used for the subsequent boosts. antigens (preferably in saline) are typically mixed with an equal volume of the adju...nd's Adjuvants may be used to produce water-in-oil emulsions of immunogens. antigens in water-in-oil emulsions stimulate high and long-lasting antibody response...
Company:Santa Cruz Biotechnology, Inc.

Crystal / Mount mounting medium - general purpose from GeneTex

Description:...easy to use and exhibits excellent optical characteristics. Crystal / Mount is the first aqueous mounting medium that permits the long-term storage of antigens localized with organic solvent-soluble chromogens such as the horseradish peroxidase chromogens: 3-amino, 9-ethylcarbazole (AEC), and 4-chloro-1-napht...
Company:GeneTex
Antigens in Biological Definition

Antibody

... of the monomer. The two variable domains bind the antigens they are specific for and that elicited their prod... The ability to bind a wide variety of foreign antigens arises from events know as somatic recombination. ... human immune system is capable of binding so many antigens is the variable region of the heavy chain. More s...

Antigen

...led, injected or comes into contact with skin. antigens are presented by a cell to its environment via a ...ells can leap into action. We can also classify antigens according to where they come from: Exogenous antigens Exogenous...

Antigenic shift

... Antigenic shift is the process by which two different strains of influenza combine to form a new subtype having a mixture of the surface antigens of the two original strains. Because the human immune system has difficulty recognizing the new influenza strain, it may be highly dangerous. Ant...

Apoptosis

...alignancy. In order to carry out their job, B and T cells must have the ability to discriminate "self" from "nonself", and "healthy" from "unhealthy" antigens (protein segments that make a good fit, like a key and a lock, with specialized receptors in B and T cell membranes). For instance, "killer" T cells ...

B cell

... lymph, but are not producing antibodies. There are two types of B cells: Plasma B cells secrete antibodies which effect the destruction of antigens by binding to them and making them easier targets for phagocytes . Memory B cells are formed specific to the antigen(s) encountered during the...

Chromatography

...on of proteins (or better: protein constructs). These constructs can be of fusion proteins with a so-called his-tag , biotinylated or possibly antigens . After purification some of these tags are usually removed and the pure protein is obtained. See also Paper chromatography of amino acids...
Antigens in Biological Dictionary

Antigens

A antibody generator or antigen (Ag) is a substance that prompts the generation of antibodies and can cause an immune response. We now know that the immune system does not consist of only antibodies. The modern definition encompasses all substances that can be... The human leukocyte a...

T lymphocytes

...T cells) differentiate ... T cell n. Any of the lymphocytes that mature in the thymus and have the ability to recognize specific peptide antigens through the receptors on their T lymphocytes Specialized blood cells that recognize invading organisms (helper T lymphocytes ) and destro...

Rhesus factor

... The term Rhesus (Rh) blood group system refers to the 5 main Rhesus antigens as well as the many other less frequent Rhesus antigens. The terms Rhesu...em The term Rhesus (Rh) blood group system refers to the 5 main Rhesus antigens (C, c, ... An agglutinable factor in human blood ... The Rhesus ...

Red blood cells

... to an adult is expected to ... red blood cells (RBCs) or erythrocytes. platelets or thrombocytes ... Red blood cells have surface antigens that differ between people and that create ... The capitalized term Red Blood Cells is the proper name in the United States for ... The firs...

Polyclonal Antibody

... antibodies to both peptides and recombinant ... Q: Which species should I use for polyclonal antibody production? ... Q: What type of antigens can be used for polyclonal antibody production? ... Polyclonal antibodies may be delivered as serum. ... The binding activity of your pol...

Polyclonal antibodies

...ibody products can be tested in our laboratories. ... Q: Which species should I use for polyclonal antibody production? ... Q: What type of antigens can be used for polyclonal antibody production? ... Custom Polyclonal Antibody production made simple. . . Producing high quality polyclo...
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