Anticholinergic

Botox injections can significantly improve quality of life for people with overactive bladders

...study and at four, 12 and 24 weeks after they received the injection. All the patients who took part in the study had failed to tolerate or respond to anticholinergic drugs, which, along with lifestyle modifications and bladder training, are traditionally used to manage OAB. Patients who received the Botox injec...

Some OTC Sleep, Cold Meds Could Harm Aging Brain

... from 27 prior studies on the relationship between anticholinergic effects and brain function, as well as looking int...tal data. The team found a consistent link between anticholinergic effects and cognitive impairment in older adults. ...ts to see if the long-term use of medications with anticholinergic effects is associated with the development of seve...

Drug Utilization Review Reveals Potentially Inappropriate Medication Use Among Elderly Population

...oided in the elderly due to an increased risk of negative health outcomes, the use of these medications, which include muscle relaxants, estrogens and anticholinergic medicines, continues to be widespread. "Inappropriate prescribing for elderly patients remains prevalent," said Catherine I. Starner, PharmD, BCP...

Indevus Pharmaceuticals Announces First Quarter Fiscal 2009 Financial Results

...treotide for acromegaly, and pagoclone for stuttering. About SANCTURA and SANCTURA XR SANCTURA(R) and SANCTURA XR(TM) belong to a class of anticholinergic compounds known as muscarinic receptor antagonists. These compounds relax detrusor smooth muscle tissue found in the bladder, thus decreasing bladder ...

Common medication associated with cognitive decline in elderly

...ine. The study examined the effects of exposure to anticholinergic medications, a type of drug used to treat a variet...findings show that chronic use of medications with anticholinergic properties may have detrimental effects on memory ...ngs on acute cognitive impairment following recent anticholinergic exposure in older medical inpatients," says Han. "...

Hector Elizondo: Caring for a Loved One with Alzheimer's Dementia

...roducts should not be taken at the same time with other medicines that have a similar effect on the body and the brain (cholinomimetic agents) or with anticholinergic medicines. Inform the doctor if the patient needs surgery requiring anesthesia while using EXELON PATCH. For full prescribing information, visit http...

Uroplasty to Highlight Urgent PC System at American Urological Association 2008 Annual Meeting

..." to be presented by Elizabeth Bozeman, M.D., on Sunday, May 18 and Monday, May 19 at 12:15 PM; -- "Urgent PC and the Patient Refractory to anticholinergic Drugs," to be presented by Scott MacDiarmid, M.D., on Sunday, May 18 and Monday, May 19 at 12:45 PM; -- "Incorporating Urgent PC into a Com...

Common Medications Could Cause Physical Impairment in the Elderly

...ine support findings released a few weeks ago that anticholinergic drugs -- which treat a variety of diseases and con...uickly than those who don't take the medicines. anticholinergic drugs work by stopping acetylcholine, a chemical t...d statement. "For older adults taking a moderately anticholinergic medication, or two or more mildly...

Commonly used medications associated with impaired physical function in older adults

... findings, which involve a class of drugs known as anticholinergic medications, are from the Ginkgo Evaluation of Mem... lead author. For older adults taking a moderately anticholinergic medication, or two or more mildly anticholinergic medications, their function was similar to that of...

Alzheimer's Disease Risk Factors May Be Gender-Specific

...he next four years, about half had no change, and about one-third regained normal levels of cognitive ability. People with depression, those taking anticholinergic drugs (which influence chemical signaling in the brain), and those with a variation in the ApoE gene (a known risk factor for dementia) were more like...

Anticholinergic in Medical Technology

Forest and Almirall Announce Positive Results of Clinical Studies for Aclidinium Bromide, a Novel, Long-Acting Anticholinergic for the Treatment for COPD

Data Presented at the 2008 International Conference of the American Thoracic Society TORONTO, May 20 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. and Laboratorios Almirall, S.A. today presented results from four clinical trials assessing the efficacy and saf...

Forest Laboratories, Inc. and Laboratorios Almirall, S.A. Provide an Update on the Aclidinium Bromide Clinical Development Program

...o improve lung function and control exacerbations. About aclidinium bromide and Genuair(R) Aclidinium bromide is a novel, long-acting inhaled anticholinergic bronchodilator which has a long residence time at the M3 receptors and a shorter residence time at the M2 receptors. Aclidinium is rapidly hydrolyzed ...

Phase III Clinical Studies of Aclidinium Bromide Show Statistical Significance vs. Placebo in Patients With Chronic Obstructive Pulmonary Disease (COPD)

...E: FRX ) and Laboratorios Almirall, S.A. today announced results from two global Phase III studies of aclidinium bromide, a novel long-acting inhaled anticholinergic for the treatment of patients with chronic obstructive pulmonary disease (COPD). In both the ACCLAIM/COPD I&II (AClidinium CLinical Trial Assessing Ef...

Olanzapine Long-Acting Injection (LAI) Shown to Maintain Treatment Benefit in Schizophrenia for up to Six Months

...cholesterol, glucose and triglyceride levels, glucosuria, increased appetite, dizziness, akathisia, parkinsonism, dyskinesia, orthostatic hypotension, anticholinergic effects, transient asymptomatic elevations of hepatic transaminases, rash, asthenia, fatigue and oedema. About Lilly Lilly, a leading innovation-d...

Watson Announces Positive Data for Its New Investigational Products for Benign Prostatic Hyperplasia and Overactive Bladder

...s. OTG is designed to provide the same advantages as the patch over a pill formulation, in terms of convenience, ease of delivery, and a lower risk of anticholinergic side effects such as dry mouth and constipation. The abstract (Steady-State Pharmacokinetics of an Investigational Oxybutynin Topical Gel in Compariso...

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)

...antipsychotics. Appropriate care is advised for patients who may exercise strenuously, be exposed to extreme heat, receive concomitant medication with anticholinergic activity, or be subject to dehydration. Esophageal dysmotility and aspiration have been associated with antipsychotic drug use, including ABILIFY; u...

Watson Announces Positive Results From Its Pivotal Study of Oxybutynin Topical Gel for the Treatment of Overactive Bladder

...treatment for OAB. By delivering oxybutynin transdermally, first-pass gastric and hepatic metabolism is bypassed, which is believed to result in lower anticholinergic side effects such as dry mouth and constipation. These side effects result in a significant level of patient non-compliance among existing oral OAB tr...

Study Results for Aclidinium Bromide, a Novel Anticholinergic, Presented at European Respiratory Society Annual Congress

...ed to other bronchodilatory agents in vitro, aclidinium demonstrated potent anticholinergic activity comparable to both tiotropium and ipratropium, but with a faster o...h COPD.(6) About Aclidinium Bromide Aclidinium bromide is a novel inhaled anticholinergic bronchodilator that is currently in phase III clinical development as a onc...

First-of-Its-Kind Study Shows Botox (Botulinum Toxin Type A) Significantly Improves Idiopathic Detrusor Overactivity (IDO) in Patients With Symptoms of Overactive Bladder

...e community and institutions). About the Study The double-blind trial included 34 patients with OAB and confirmed IDO who had failed on a trial of anticholinergic therapy for six weeks or more due to either poor efficacy or tolerability. They were randomly assigned to treatment with BTX-A 200 U (BOTOX(R)) (16 pa...

Six-Week Investigational Study In Adults With Major Depressive Disorder Evaluates The Effectiveness of Adjunctive Aripiprazole Therapy With Antidepressants

...antipsychotics. Appropriate care is advised for patients who may exercise strenuously, be exposed to extreme heat, receive concomitant medication with anticholinergic activity, or be subject to dehydration. As antipsychotics have been associated with esophageal dysmotility and aspiration, aripiprazole should be us...

Anticholinergic in Biological Technology

Data from Two Pivotal Trials of AMRIX, a New Once-Daily Extended-Release Muscle Relaxant, Presented at the American Academy of Pain Medicine Meeting

...d be used with caution in patients with a history of urinary retention, angle-closure glaucoma, increased intraocular pressure, and in patients taking anticholinergic medication. For complete product information, visit http://www.amrix.com . About Cephalon, Inc. Founded in 1987, Cephalon, Inc. is an internati...

U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) as the First Medication for Add-On Treatment of Major Depressive Disorder (MDD)

...antipsychotics. Appropriate care is advised for patients who may exercise strenuously, be exposed to extreme heat, receive concomitant medication with anticholinergic activity, or be subject to dehydration. The possibility of a suicide attempt is inherent in psychotic illnesses and bipolar disorder, and close super...