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Ankylosing in Medical News

Study aims to induce recovery from ankylosing spondylitis

Chinese patients will soon have the opportunity to take part in a study of a novel therapy aimed at reversing the autoimmune disease, ankylosing spondylitis. Approximately 200 patients will be chosen to participate in a clinical trial that aims to merge the latest molecular discoveries published b...

SIMPONI(TM) (golimumab) Receives FDA Approval as First Once-Monthly Anti-TNF for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

First Subcutaneous Anti-TNF to Launch with Three Rheumatic Indications Simultaneously and with Novel SmartJect(TM) Autoinjector HORSHAM, Pa., April 24 /PRNewswire/ -- Centocor Ortho Biotech Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved SIMPONI (golimumab)...

Medarex to Receive Milestone Payment for Approval of SIMPONI(TM) for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

- The second approved antibody generated from Medarex's UltiMAb(R) technology platform - PRINCETON, N.J., April 14 /PRNewswire-FirstCall/ -- Medarex, Inc. (Nasdaq: MEDX ) today announced that it will receive a milestone payment of an undisclosed amount from its licensing partner, Centocor O...

Centocor, Inc. Submits Application to FDA Requesting Approval of Golimumab for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

Extensive Clinical Development Program Investigating Golimumab in the Treatment of These Diseases Serves as Basis for the Application HORSHAM, Pa., June 27 /PRNewswire/ -- Centocor, Inc. announced today that a Biologics License Application (BLA) has been submitted to the U.S. Food and Drug...

Data Show that Abbott's HUMIRA(R) (adalimumab) Reduced the Signs and Symptoms of Ankylosing Spondylitis Up to Three Years

PARIS, June 13 /PRNewswire-FirstCall/ -- Abbott announced new data from the open-label extension of the ATLAS (Adalimumab Trial Evaluating Long-Term Efficacy and Safety in AS) phase III clinical trial, which showed HUMIRA(R) (adalimumab) reduced the signs and symptoms of ankylosing spondylitis...

Abbott Study Examines Rates of Uveitis (Inflammation of the Eye) in Ankylosing Spondylitis Patients Treated with HUMIRA(R) (adalimumab)

Painful Eye Condition Can Occur in Up to 40 Percent of People with Ankylosing Spondylitis (Spinal Arthritis) ABBOTT PARK, Ill., Nov. 8 /PRNewswire-FirstCall/ -- A study of ankylosing spondylitis (AS) patients treated with Abbott's HUMIRA(R) showed a decrease in the rate of uve...

Amgen and Wyeth Statement on FDA Announcement About Tumor Necrosis Factor (TNF) Blockers

...ate in patients who do not respond adequately to methotrexate alone. ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis. ENBREL is indicated for the treatment of adult patients (18 years or older) with chronic moderate to severe plaque psoriasis who a...

IFX anti-TNF therapy associated with clinical benefit over 5 years in patients with active AS

...ears of receiving infliximab (IFX) anti-TNF therapy, 61.8% of patients with ankylosing spondylitis (AS) showed substantial clinical benefit (ASAS40, ASsessment in...d the United Kingdom) recruited to the 96-week open-label EASIC (European ankylosing Spondylitis Infliximab Cohort) trial had previously participated in the 2-y...

Diagnosis of arthritis 5 years earlier in childless women compared to those with children

...agen, Denmark, Thursday 11 June 2009: Nulliparous women (those who have not given birth to children) are diagnosed with chronic arthritides (including ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis (RA) an average of 5.2 years before parous women (those who have given birth to children), a...

Johnson & Johnson Highlights Pharmaceutical Growth Strategies and Robust Pipeline to Address Unmet Medical Needs

...ricans suffer from diseases of the immune system, and there are approximately 10 million people living with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis and plaque psoriasis. Infectious Diseases -- The company is exten...
Ankylosing in Medical Technology

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

Positive Opinion Recommends Approval of New Anti-TNF Therapy in Three Rheumatic Diseases with Novel SmartJect(TM) Autoinjector HORSHAM, Pa. and KENILWORTH, N.J., June 26 /PRNewswire-FirstCall/ -- Centocor Ortho Biotech Inc. and Schering-Plough Corporation (NYSE: SGP ) announced today that t...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

Long-Term Data in Patients Receiving Every-Four-Week Subcutaneous SIMPONI Presented at 2009 EULAR Annual Congress COPENHAGEN, June 9 /PRNewswire/ -- Findings from open-labeled, uncontrolled extensions of two randomized, placebo-controlled Phase 3 studies showed that subcutaneous (SC) inject...

New Anti-TNF Golimumab Significantly Reduced Signs and Symptoms of Ankylosing Spondylitis According to Phase 3 Study Findings

Patients with Painful and Progressive Form of Inflammatory Spinal Arthritis Receiving Monthly Golimumab Treatment Showed Marked Improvements in Physical Function BOSTON, Nov. 7 /PRNewswire/ -- More than half of patients receiving monthly subcutaneous (SC) injections of...

Remicade Two Year Data in Ankylosing Spondylitis Show Improvement in Spinal Mobility and Spinal Inflammation

Findings from the ASSERT Trial Presented at EULAR BARCELONA, Spain, June 15, 2007 /PRNewswire-FirstCall/ -- Data presented today at the European League Against Rheumatism (EULAR) Annual European Congress of Rheumatology showed that patients with ankylosing spondylitis (AS) who received REMICADE(R)...

New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients

...oid arthritis in adults, in combination with methotrexate; active psoriatic arthritis in adults, alone or in combination with methotrexate; and active ankylosing spondylitis in adults. Indications in Canada: In Canada, SIMPONI, in combination with methotrexate (MTX), is indicated for reducing the signs...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

..., rheumatology and dermatology. REMICADE has demonstrated broad clinical utility with indications in Crohn's disease (CD), rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), ulcerative colitis (UC), pediatric Crohn's disease (PCD) and psoriasis (PsO). The safety and efficacy of...

Schering-Plough Highlights R&D Pipeline Progress, Innovation and Breadth of Research Projects

...I(TM)* (golimumab), a once-monthly subcutaneous anti-TNF agent for inflammatory and autoimmune disorders (under review in EU for rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis, and in Phase III for ulcerative colitis); Schering-Plough has exclusive marketing rights to golimumab outside the...

CHMP Recommends Approval of New Indication for Enbrel(R) as Treatment for Severe Psoriasis in Paediatric Patients

...in patients with polyarticular symmetrical subtypes of the disease. ankylosing spondylitis Treatment of adults with severe active ankylosing spondylitis who have had an inadequate response to conventional therapy. ...

New Findings Show Efficacy of REMICADE(R) Compared With Azathioprine in Treatment of Crohn's Disease According to First-of-its Kind Study

...al. People who have been treated for rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis or plaque psoriasis for a long time, parti...ought innovation to the treatment of Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, ulcerative colitis, pediatric Crohn's dis...

Continuous Treatment With Abbott's HUMIRA(R) Achieves Superior Long-Term Efficacy for Psoriasis Patients Compared to Interrupting Treatment

...RA HUMIRA is the only fully human monoclonal antibody approved for the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), psoriasis, ankylosing spondylitis (AS), Crohn's disease and juvenile idiopathic arthritis (JIA) in the United States and Europe. HUMIRA resembles antibodies normally found ...
Ankylosing in Medical Products

Clinical Neurology 2007

Description:...lsy, ALS, seizures, strokes, headaches, coma, cervical spine problems, low back pain, radiculopathy, sciatica, myofacial pain, sacroiliac dysfunction, ankylosing spondylitis and pseudo-neurological syndromes. To help you manage and treat anything that walks through the door. It is constantly updated, adding the...
Company:Mobipocket.com
Ankylosing in Medical Dictionary

Spondylosis

...roots with subsequent pain or paresthesia in the limbs. Spondylosis is degenerative arthritis of the joints between the centra of ... ankylosing spondylitis · Spondylosis (Spondylolysis, Spondylolisthesis) · Spinal ... The degenerative process of spondylosis (spinal osteoarthritis) ...

Spondylitis

...inal column may be called spondylopathy, also. ankylosing spondylitis , a form of Spondyloarthritis, is a c...using eventual fusion of the spine. More about ankylosing Spondylitis : Causes and symptoms Diagnosis Treat...rnative treatment Prognosis Prevention Resources ankylosing Spondylitis spondylitis n. Inflammation of...

Psoriatic arthritis

... conditions, cosmetic surgery, ... Perspectives Of ankylosing Spondylitis & Psoriatic Arthritis 2004 ...... Learn more about this painful condition here. ankylosing spondylitis and related disease information. ankylosing spondylitis ... The least common type of psoria...

Mandible

...in the Edwin Smith Papyrus in ... Mandible interfaces with skull base via the. TMJ and is held in position by the muscles ... mandible fx is ankylosing of the TMJ with. impact on jaw growth ... Gray, Henry. 1918. Anatomy of the Human Body. II. Osteology. 5b. 8. The Mandible (Lower Jaw) ... The...

Joints

...rthroses, are usually adaptations to growth rather than ... Read about ankylosing spondylitis (a form of chronic inflammation of the spine and the sacroiliac joints ), which causes spinal pain and stiffness. As ankylosing ... ...

Iritis

... The symptoms of iritis include light sensitivity, red eye, blurred vision, ... Iritis is inflammation of the iris caused by eye trauma, ankylosing spondylitis, ... Iritis Overview ... This is termed iritis . ... List of 56 disease causes of Iritis , patient stories, diagnostic guides, m...

Ankylosing spondylitis

... ankylosing spondylitis , a form of Spondyloarthritis, is a ch...sion of the spine. Provides information about ankylosing spondylitis , Reiter's syndrome, psoriatic arthr...associated with inflammatory bowel disease. ankylosing spondylitis and related disease information. ...
Ankylosing in Biological News

Major genetic breakthrough for ankylosing spondylitis brings treatment hope

Research funded by the Wellcome Trust and the Arthritis Research Campaign has identified two genes implicated in the disease ankylosing spondylitis, a common disease primarily causing back pain and progressive stiffness. The research, published online today in Nature Genetics, suggests that a trea...

Johnson & Johnson honors 2008 recipients of the Dr. Paul Janssen Award for Biomedical Research

...e more than 80 types of autoimmune diseases including rheumatoid arthritis, ankylosing spondylitis and ulcerative colitis. The safety and efficacy of anti-TNF th...thritis has subsequently led to TNF blockade in Crohn's disease, psoriasis, ankylosing spondylitis and ulcerative colitis," said Feldmann. "Blocking other cytok...

Study reveals 2 genes linked to disabling arthritis

...nes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in ...Genetics. The study revealed two genes linked to ankylosing spondylitis: ARTS1 and IL23R, both of which influe...trol subjects. In addition to Graves disease and ankylosing spondylitis, the study mined for common genetic va...

Clinical studies show REMICADE reduces incidence of bowel surgeries in ulcerative colitis patients

...: gastroenterology, rheumatology and dermatology. REMICADE has demonstrated broad clinical utility in Crohn's disease (CD), rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), ulcerative colitis (UC), pediatric Crohns disease (PCD) and psoriasis (PsO). The safety and efficacy of R...

Monoclonal antibody reduces exacerbations in asthmatics

...senger protein, a cytokine, produced by white blood cells. "Anti-TNFá therapy has been shown to be effective in patients with rheumatoid arthritis, ankylosing spondylitis, Crohn's disease and psoriasis, but ineffective in patients with chronic obstructive pulmonary disease (COPD)," said Dr. Hansel. "Prelimin...
Ankylosing in Biological Technology

Health Canada Approves SIMPONI(TM) (golimumab) for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

Canadian Approval Is World's First Regulatory Approval for SIMPONI HORSHAM, Pa. and KENILWORTH, N.J., April 13 /PRNewswire-FirstCall/ Centocor Ortho Biotech Inc. and Schering-Plough Corporation (NYSE: SGP ) today announced that Health Canada has granted approval of SIMPONI (TM) (go...

Medarex Receives Milestone Payment for Submission of Regulatory Application Requesting Approval of Golimumab (CNTO 148) in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

PRINCETON, N.J., March 20 /PRNewswire-FirstCall/ -- Medarex, Inc. (Nasdaq: MEDX ) today announced that it has received a milestone payment of an undisclosed amount from its licensing partner, Centocor, Inc., for the submission of a Marketing Authorization Application to the European Medicines...

Centocor, Inc. and Schering-Plough Submit Application Requesting Approval of Golimumab in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

HORSHAM, Pa. and KENILWORTH, N.J., March 18 /PRNewswire/ -- Centocor, Inc. and Schering-Plough Corporation (NYSE: SGP ) announced today that a Marketing Authorization Application (MAA) has been submitted to the European Medicines Agency (EMEA) requesting the approval of golimumab (CNTO 148) a...

Schering-Plough Reports Financial Results for 2009 Second Quarter

... for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis; SIMPONI was also launched in Canada i... rheumatoid arthritis, early rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis... symptoms in patients with psoriatic arthritis and ankylosing spondylitis. Separately, a new analysis was repor...

Baseline Research Indicates High Interest in Centocor-Ortho Biotech's SIMPONI(R)

...TNF-alpha therapy, SIMPONI is approved for the treatment of moderately to severely active rheumatoid arthritis, active psoriatic arthritis, and active ankylosing spondylitis. The product will be available in two dosing delivery forms: the SIMPONI SmartJect autoinjector and a prefilled syringe. LaunchT...

Golimumab Phase 3 Data Show Significant Improvement In Physical Function In Patients with Rheumatoid Arthritis

...a study in a methotrexate-naive patient population, psoriatic arthritis and ankylosing spondylitis, golimumab is being studied as an every four-week subcutaneous ...ought innovation to the treatment of Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, ulcerative colitis, pediatric Crohn's dis...

One-Year Data Show Golimumab Improved Signs and Symptoms In Patients with Psoriatic Arthritis In Phase 3 Study

...rheumatoid arthritis (RA), psoriatic arthritis and ankylosing spondylitis. About the GO-REVEAL Trial The GO-...rheumatoid arthritis (RA), psoriatic arthritis and ankylosing spondylitis, golimumab is being studied as an ever...reatment of Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, ulcerative colit...

Johnson & Johnson Honors 2008 Recipients of The Dr. Paul Janssen Award for Biomedical Research

...e more than 80 types of autoimmune diseases including rheumatoid arthritis, ankylosing spondylitis and ulcerative colitis. The safety and efficacy of anti-TNF the...thritis has subsequently led to TNF blockade in Crohn's disease, psoriasis, ankylosing spondylitis and ulcerative colitis," said Feldmann. "Blocking other cytokin...

FDA Extends Review Timeline for Ustekinumab Biologic License Application Three Months

...vative biomedicines that transform patients' lives. Centocor has already brought innovation to the treatment of Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, ulcerative colitis, pediatric Crohn's disease and psoriasis. The world leader in monoclonal antibody production an...

Phase 3 studies show golimumab significantly improved signs and symptoms of rheumatoid arthritis

...erapy with ongoing studies for the treatment of RA, psoriatic arthritis and ankylosing spondylitis. In the study, GOlimumab FOR subjects With Active RA Despit... monthly subcutaneous treatment for adults with RA, psoriatic arthritis and ankylosing spondylitis. The initial submission and Phase 3 development programs are u...
Ankylosing in Biological Dictionary

Biologics

...rtain immune cells—either T cells or ... Biologics Don't raise cancer risk in RA Patients ... Cost of Biologics - Who holds the answer? ... ankylosing spondylitis, Biologics , Cost, Juvenile Arthritis, ... Biologics completes rebranding process as cancer management company > Complete story...
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