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Analgesic in Medical News

New Drug Application Submitted to FDA for Investigational Analgesic Tapentadol Immediate Release Tablets

RARITAN, N.J., Jan. 23 /PRNewswire-USNewswire/ -- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. announced that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for tapentadol hydrochloride immediate release (IR) tablets, an investig...

Labopharm To Present Poster On Onset Of Analgesic Effect Of Once-Daily Tramadol At Congress Of The European Society Of Regional Anaesthesia And Pain Therapy

- Article Discussing Analgesic Efficacy of Labopharm's Once-Daily Tramadol Published in Journal of Pain and Symptom Management - - Company Secures Marketing Partner for Once-Daily Tramadol in Israel - LAVAL, QC, Sept. 14 /PRNewswire-FirstCall/ - Labopharm Inc. (TSX: DDS; NASDAQ: DDSS)...

Chronic Pain Sufferers Report Relief: DRJ Group Teams With Adult Foster Care Facilities to Evaluate Effectiveness of Stopain Topical Analgesic

ENCINITAS, Calif., April 7 /PRNewswire/ -- DRJ Group Inc., the makers of all-natural Stopain (R) topical analgesics, today announced the results of an informal study conducted with chronic pain sufferers at two adult foster care facilities. The test was conducted with residents living a...

Ranbaxy In-Licences NDDS Analgesic Molecule From Ethypharm

Ranbaxy Laboratories Limited today entered into an in-licensing agreement with Ethypharm S.A., France for novel drug delivery system (NDDS) analgesic // , Tramadol in the Indian market The agreement was signed with Ethypharm LL India (Ethypharm), the wholly-owned subsidiary of the French drug major...

Nanotechnology Transforms Pain Relief

...phen, the active ingredient in Tylenol(R) and other commonly prescribed pain relievers, has been linked to liver disease. Methyl Salicylate, a topical analgesic found in the likes of Bengay(R) and Icy Hot(R), can lead to fatal overdose if applied excessively. MyOmega(R) deters excessive application by avoiding...

AcelRx Announces Perfect Performance of Handheld Component of ARX-01 Sufentanil NanoTab PCA System in a Phase 2 Study

...e of the IV delivery mode poses infection risk as well as predisposition to analgesic gaps due to infiltrated and dislodged IV catheters. Additionally, the compl...utic index opioid approved for IV and epidural administration. Although the analgesic efficacy of sufentanil has been well established, its use has been limited ...

CCA Industries, Inc. Reports Second Quarter Earnings and Dividend for the Third Quarter.

...olar Sense" sun protection products, "Hair Off" hair removal and depilatory products, "Wash 'N Curl" shampoos and conditioners and Pain Bust RII, an analgesic product. Statements contained in the news release that are not historical facts are forward looking statements as that term is defined in th...

Transdel Pharmaceuticals Completes Enrollment in Phase 3 Clinical Study for Novel Topical Pain Treatment

...dal anti-inflammatory drug ("NSAID"), through the skin directly into the underlying tissues where the drug exerts its well-known anti-inflammatory and analgesic effects. The Company intends to leverage its Transdel(TM) platform technology to expand and create a portfolio of topical products for a variety of i...

Pain Medicine Experts Recommend Safe and Responsible Use of Acetaminophen

...cations without deterring access to appropriate pain care for legitimate patients and the need for physicians to adhere to responsible analgesic prescribing practices. The Academy will continue to work towards these goals through advocacy, research, promotion of best clinical pr...

Cell transplantation and cardiac repair

.... Amann noted that the patients with limb salvage had better baseline perfusion than the eventually amputated patients. Among the limb-salvaged group, analgesic consumption was reduced by 62 percent and their total walking distance improved from zero to 40 meters. "This study found that after aBMC, in additi...
Analgesic in Medical Technology

Cara Therapeutics Initiates Phase II Proof-Of-Concept Trial of Novel Analgesic in Acute Post-Operative Pain

SHELTON, Conn., Jan. 12 /PRNewswire/ -- Cara Therapeutics, Inc. today announced that it is initiating a Phase II clinical trial of its long-acting peripheral kappa opioid agonist, CR845. The Phase II multi-center, double-blind, placebo-controlled trial will be conducted in the United States and wi...

TorreyPines Therapeutics Initiates Clinical Trial to Evaluate Analgesic Effect of Oral Prodrug of Tezampanel

LA JOLLA, Calif., June 4 /PRNewswire-FirstCall/ -- TorreyPines Therapeutics, Inc. (Nasdaq: TPTX ) today announced it has initiated a clinical trial to evaluate the analgesic effect of NGX426, the oral prodrug of its lead product candidate, tezampanel. The randomized, double-blind, placebo-c...

Acura and King Receive FDA Complete Response Letter Regarding Acurox(R)

...tered, immediate release tablet containing oxycodone HCl as its sole active analgesic ingredient with a proposed indication for the relief of moderate-to-severe ...ntly developed Acurox(R) Tablets and are developing three additional opioid analgesic product candidates utilizing Aversion(R) Technology pursuant to a 2007 Lice...

AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain

...e of the IV delivery mode poses infection risk as well as predisposition to analgesic gaps due to infiltrated and dislodged IV catheters. Additionally, the compl...x opioid approved for intravenous and epidural administration. Although the analgesic efficacy of sufentanil has been well established, its use has been limited ...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

...ROX(R) and EMBEDA(TM) (ALO-01), two novel opioid analgesic formulations that are in development, at the 71st ...te to severe pain. A Phase III study evaluated the analgesic efficacy and safety of ACUROX(R) in adults with mo...tablet containing oxycodone HCl as its sole active analgesic ingredient with a proposed indication for the reli...

New Phase 3 Study of Tapentadol Immediate Release Tablets Published in Current Medical Research and Opinion Journal

...ts from the new Phase 3 study of tapentadol IR tablets, a prescription oral analgesic approved by the U.S. Food and Drug Administration (FDA) in November 2008, s...use it shows that patients treated with tapentadol IR experienced effective analgesic relief of moderate to severe acute pain with fewer incidences of nausea and...

Cadence Pharmaceuticals Submits Acetavance New Drug Application for the Treatment of Acute Pain and Fever

...nd children. If approved, Acetavance would become the first new intravenous analgesic approved in the United States in more than 20 years and the only approved i...tipation, cognitive impairment, and others. The only non-opioid intravenous analgesic currently available in the United States is the NSAID, ketorolac. Post-oper...

AcelRx Initiates a Phase 2 Study to Evaluate Functionality of Its ARX-01 Sufentanil NanoTab PCA System

...e of the IV delivery mode poses infection risk as well as predisposition to analgesic gaps due to infiltrated and dislodged IV catheters. Additionally, the comp...x opioid approved for intravenous and epidural administration. Although the analgesic efficacy of sufentanil has been well established, its use has been limited ...

QRxPharma Successfully Completes Comparative Study for Dual-Opioid(TM) Pain Therapy

...sured by the incidence and intensity of opioid-related adverse events. In terms of reduced pain intensity scores and other related measures, the analgesic effects of 12mg/8mg MoxDuo(TM) IR were 80-100% greater than the components, morphine or oxycodone. The 6mg/4mg MoxDuo(TM) IR dose also showed similar...

DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program

...opioid experienced patients to TRANSDUR-Sufentanil to achieve an acceptable analgesic and side effect profile. Secondary objectives: Evaluate...regimens, two acceptable dose titration intervals have achieved the desired analgesic effect and side-effect profile, and therefore are expected to be utilized i...
Analgesic in Medical Products

Physician's Drug Handbook, 10th Ed

Features:...vals and new indications and an updated appendix on herbal medicines Other appendices include guidelines for use of selected antimicrobials, selected analgesic combination products, topical drugs, cytochrome P-450 enzymes and common drug interactions, therapeutic drug monitoring, dialyzable drugs, and phone n...
Company:Skyscape, Inc.

Hiro 3.0

Features:... High emission power Acts effectively at depth Rapid analgesic effect High guarantee of safety Controlled release of energy Observes the thermal relaxation time of tissues ...
Company:DEKA Research & Development Corp.
Analgesic in Medical Dictionary

Urogenital

... for the secretion ... Urogenital Disorders. Search. Query. A Well Timed High Five A Well ... Overview of Urinary/ Urogenital System Disorders. analgesic Nephropathy. Bladder Cancer ... Buy Imaging Of Urogenital Diseases for $151.20 today & save. Buy.com books: new ~ used ~ paperbacks ~ NYTBS ...

Salve

...Book your hotel in Salve online with best price guarantee on Booking.com. We offer a large selection of quality hotels in Salve . salve n. An analgesic or medicinal ointment. Something that soothes or heals; a balm. ... For other uses, see Salve (disambiguation) ... Hotels.com offers great rates...

Reflux nephropathy

...ied when small and scarred kidneys are associated with vesico-ureteric reflux (VUR). CPN being the commonest cause, there are other causes including analgesic nephropathy and obstructive injury. Scarring is essential in developing RN... Reflux nephropathy occurs when these valves fail, allowing ur...

Nephropathy

... Causes of nephropathy include administration of analgesics, xanthine oxidase ... analgesic nephropathy · Renal osteodystrophy · Nephroptosis · Abderhalden ... Diabetic nephropathy , also known as Kimmelstiel-Wilson syndrome and in...

Interstitial nephritis

... ... Interstitial nephritis is a kidney disorder in which the spaces between the ... to a drug (acute interstitial allergic nephritis ) analgesic nephropathy ... ...

Esophagitis

...gitis is an inflammation of the lining of the esophagus, the tube that ... To treat pain brought on by esophagitis , your doctor may give you an analgesic ... Herpes esophagitis is a viral infection that involves inflammation and ulcers in ... The herpes simplex virus causes herpes e...

Aspirin overdose

... Aspirin (USAN), also known as acetylsalicylic acid, is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. An overdose of aspirin means you ...

Analgesic nephropathy

... analgesic nephropathy is injury to the kidney caused by analgesic medications such as aspirin, phenacetin, and para...ods may lead to chronic kidney disease. ... analgesic Nephropathy . Treatment. For More Information .....

Acetaminophen overdose

...cetamol (INN) or acetaminophen ) (USAN) is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). It is commonly used for th..... Paracetamol toxicity is caused by excessive use or overdose of the analgesic drug paracetamol . Mainly causing liver injury, paracetamol toxicity is...
Analgesic in Biological News

Study first to pinpoint why analgesic drugs may be less potent in females than in males

ATLANTA -- Investigators at Georgia State University's Neuroscience Institute and Center for Behavioral Neuroscience are the first to identify the most likely reason analgesic drug treatment is usually less potent in females than males. This discovery is a major step toward finding more effective ...

Metastatic bone disease patients can walk in Lazarus' footsteps

...asty provided effective pain regression for individuals with both painful bone metastases and benign lytic lesions that didn't respond to conventional analgesic treatment. Bones are the third most common location where cancer cells spread and metastasize. Bone metastases occur when cancer cells gain access ...

Pain is in the eyes of the beholder

...n't mean that pain is any less real, they may lead to a new therapeutic approach for reducing pain. His team is now testing visual manipulations as an analgesic strategy for use in clinical settings. ...

How does the opioid system control pain, reward and addictive behavior?

... mu-opioid-receptor The finding that morphines analgesic and addictive properties are abolished in mice lac... behaviors. The lack of mu-receptors abolishes the analgesic effect of morphine, as well as place-preference ac...therapy. Therefore, in addition to their potential analgesic activity, delta-agonists may be useful in improvin...

Old memory traces in brain may trigger chronic pain

... pain long after their injuries have actually healed" The definitive answer -- and an effective treatment -- has long eluded scientists. Traditional analgesic drugs, such as aspirin and morphine derivatives, haven’t worked very well. A Northwestern University researcher has found a key source of chroni...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

...CSF. The methanol receptor, and other temperature receptors discovered in recent years by the Julius lab, offer potential targets for developing analgesic drugs that act in the peripheral, nervous system, rather than centrally, where opiate receptors act, he says. The finding is a milestone in an in...

Scripps research team sheds light on long-sought cold sensation gene

...trast, TRPM8-deficient mice did not receive any acute pain relief from the cold plate suggesting that cold activation of TRPM8 can mediate some of the analgesic effects of cold. Just how the same sensation can be interpreted as unpleasant under certain circumstances and pleasant in others is still not cle...

Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight

...tory mediator that controls a variety of physiological functions including fever, fertility, and blood pressure. The most common anti-inflammatory and analgesic treatments like ibuprofen are aimed at reducing PGE2 signaling at all four prostaglandin receptors. The absence of EP3 receptors has long been kn...

A new target for painkillers

...as the "alpha9alpha10 nicotinic acetylcholine receptor." "The numerous analgesic compounds currently available are largely ineffective" for chronic nerve pa...y sciatica, with no adverse effects. Daily injections "produced a sustained analgesic effect," the researchers wrote. RgIA was such a potent pain reliever t...

Virtual realities against pain

...significantly reduce the pain associated with medical treatment. The use of analgesic was clinically revealing in most cases, especially in patients with very hi...nclude that ADTs are very useful as analgesic, and can reduce the amount of analgesic administered. This new field of study can begin to move forward beyond its ...
Analgesic in Biological Technology

QRxPharma Initiates Comparative Phase 2 Proof-of-Concept Study for MoxDuo(TM) IV Pain Therapy

...ree years. "QRxPharma's goal is to bring to market complementary analgesic options for pain specialists, delivering greater patient tolerability and e...ents than morphine alone at equianalgesic doses and (2) whether the maximum analgesic effect of MoxDuo(TM) IV is superior to morphine alone. The study...

Supelco(R) and MIP Technologies Launch New SPE Product for the Selective Extraction of NSAIDs From Environmental Water

...e most highly consumed pharmaceuticals in the world." Ibuprofen, diclofenac and naproxen are non-steroidal anti-inflammatory drugs that have analgesic and antipyretic activities. Clofibric acid is an active metabolite of clofibrate, etofibrate and etofyllinclofibrate. These compounds are used as bloo...

QRxPharma Initiates Second Comparative Study for MoxDuo(TM) IR Dual-Opioid(TM) Pain Therapy

...of a comparative 3-arm pilot study to evaluate the analgesic efficacy and safety profile of MoxDuo(TM) IR (imme...bjectives of the study include: (1) comparing the analgesic efficacy and safety profile of MoxDuo(TM) IR again...pulation. MoxDuo(TM) IR is the first patented analgesic product in the world that consists of two opioid d...

AcelRx Pharmaceuticals Hires Roman Skowronski, M.D., Ph.D. as Vice President of Clinical Development

...o have recruited a candidate of Roman's caliber," stated Pamela Palmer, MD, PhD. "He brings a wealth of knowledge and experience in the management of analgesic drug development programs as well as drug-device combination products." AcelRx Pharmaceuticals, Inc. is an emerging specialty pharmaceutical c...

Anesiva Phase 3 Trial of Adlea Meets Primary Endpoint to Significantly Reduce Pain After Total Knee Replacement Surgery

...ng that the Phase 3 trial evaluating Adlea(TM), its long-acting, non-opioid analgesic drug candidate, achieved its primary efficacy endpoint of reducing post-sur...cebo over the study duration. "These compelling results confirm the analgesic contribution of Adlea during the most critical period following total knee ...

QRxPharma Initiates Comparative Study for MoxDuoIR(TM) Dual-Opioid(TM) Pain Therapy

...evaluate the efficacy and safety profile of MoxDuoIR(TM) against equivalent analgesic doses of morphine and oxycodone alone for the treatment of acute moderate t...to provide direct evidence of enhanced efficacy when compared to equivalent analgesic doses of morphine and oxycodone alone," said Dr. John Holaday, Managing Dir...

New Publications Show Noninvasive Magnetic Resonance-Guided Focused Ultrasound to be a Potentially Safe, Effective Pain-Relieving Treatment for Bone Metastases

...substantial pain relief at the follow-up visit three days after their treatment. A majority of the patients also decreased their opioid and non-opioid analgesic intake following treatment. No device-related adverse events were reported. In subgroup analysis, researchers from Mount Sinai Hospital in Tor...

Transdel Pharmaceuticals, Inc. Retains The Investor Relations Group

... tissue where the drug exerts its prolonged localized anti-inflammatory and analgesic effect. The Company is also investigating other novel and generic drugs and...reach the target soft tissue and exert its well-known anti-inflammatory and analgesic effects. The Company is also investigating other drug candidates and treatm...

Transdel Pharmaceuticals to Present at Rodman & Renshaw 10th Annual Global Healthcare Conference

...del(TM), the Transdel(TM) cream allows the active ingredient ketoprofen to reach the target soft tissue and exert its well-known anti-inflammatory and analgesic effects. The Company is also investigating other drug candidates and treatments for transdermal delivery using the patented Transdel(TM) platform tech...

TorreyPines Therapeutics Begins Dosing in a Phase I Multiple Dose Clinical Trial of NGX426, Oral Prodrug of Tezampanel

...m, acting chief executive officer of TorreyPines Therapeutics. "The multiple dose trial, as well as the ongoing Phase I capsaicin trial evaluating the analgesic effect of NGX426, will guide us in planning our Phase II program." Tezampanel and NGX426, are the first AMPA/kainate-type glutamate receptor antagon...
Analgesic in Biological Definition

Drug

...lands . Classification Drugs may be classified in many different ways, according to mechanism of action, effects, or even legal status. analgesic (painkiller) drugs Non-NSAID antipyretics Acetaminophen (also known as paracetamol, or under one of its trade names Tylenol), which can cau...
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