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Amphotericin in Medical News

FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia

...caution and monitored for treatment response The following drugs should not be administered simultaneously through the same Y-site as TYGACIL: amphotericin B and diazepam For a copy of TYGACIL Prescribing Information, please visit www.Wyeth.com . About Wyeth Wyeth Pharmaceuticals,...

Voriconazole: A highly potent treatment for fungal infections

...e antifungal agents in vitro, and also to check for resistance to voriconazole. The researchers analyzed the effect of itraconazole, fluconazole, amphotericin B and voriconazole versus 1763 yeasts isolated from samples obtained from 472 patients. The yeast cultures obtained were predominantly Candida spp . ...

Bihar Under the Grip of Kala Azar

...sease by 2010. Thakur said that continued spraying of insecticides for at least five years in a phased manner and supervised administration of amphotericin B could eliminate the disease. "There is an urgent need for at least 100,000 vials of Amphotericin-B to control the rising incidence of kala a...

New Anti Fungal Drug Eraxis as Good as the Older Medicine

...g for people who are already ill and for babies who are born pre-term and tiny. The first compound used to treat candidiasis (yeast infection) was amphotericin B, which was effective but was limited by side effects. Over the years, less toxic alternatives were developed such as fluconazole and a newer class...

Carbon Nanoneedles For Drug Delivery

...otubes were taken up to a significant extent.” The research team, with colleagues over in France, have experimented with delivering drugs such as amphotericin B (an anti-fungal treatment) and methotrexate (an anti-cancer drug) using the functionalised carbon nanotubes, but encountered some obstacles with dru...

Fight against Fungus - A new ray of hope

...ue" of fungal infections in hospitals has been combated by two main drugs - amphotericin B and fluconazole. While the former drug, which has been around for nearly ... The study concluded that the new drug, caspofungin was as effective as amphotericin B without as many side effects. However one of the main disadvantages of th...
Amphotericin in Medical Technology

Wyeth Receives Approvable Letter from FDA for TYGACIL for the Treatment of Patients with Community-Acquired Pneumonia

...ion and monitored for treatment response -- The following drugs should not be administered simultaneously through the same Y-site as TYGACIL: amphotericin B and diazepam For a copy of TYGACIL Prescribing Information, please visit http://www.Wyeth.com . About Wyeth Pharmaceuticals Wyeth Pharmaceuti...

More Clinical Data Required to Support European Approval of CAP Indication for TYGACIL

...ion and monitored for treatment response -- The following drugs should not be administered simultaneously through the same Y-site as TYGACIL: amphotericin B and diazepam Please see Prescribing Information. Wyeth Pharmaceuticals: Wyeth Pharmaceuticals, a division of Wyeth has leading products in the...

FDA Accepts Wyeth's Supplemental New Drug Application for Tygacil for the Treatment of Patients with Community-Acquired Pneumonia

...and monitored for treatment response. -- The following drugs should not be administered simultaneously through the same Y-site as Tygacil: amphotericin B and diazepam. For a copy of Tygacil Prescribing Information, please visit http://www.wyeth.com . Wyeth Pharmaceuticals, a division of Wyeth, has ...

New Data From Large Safety Analysis of MYCAMINE Shows Favorable Clinical Safety Profile

...nts, even in longer periods of exposure. Comparative study data showed MYCAMINE had a similar safety profile to fluconazole, caspofungin and liposomal amphotericin B. These data were presented today at the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). MYCAMINE is approved ...

Data on Telavancin and Micafungin Hold Promise of New Therapeutic Options in Fight Against Serious Infectious Disease

...cy comparable to established treatments, liposomal amphotericin B (L-AmB) and intravenous caspofungin,(9) and that...f the safety of micafungin compared with liposomal amphotericin B in a large, phase III trial in patients with inv... (11) Arrieta A et al. Micafungin versus liposomal amphotericin B (AmBisome(R)) in paediatric patients with invasi...

Phase 2 Clinical Results of Ganite Plus Standard Therapy in Patients with Relapsed/Refractory Lymphoma Presented at ASCO

...rated by patients who received the drug in clinical trials, concurrent use of Ganite with other potentially nephrotoxic drugs like aminoglycosides and amphotericin B may increase the risk for developing severe renal insufficiency in patients with cancer-relapsed hypercalcemia. If use of a potentially nephrotoxic ...

Phase 2 Clinical Results of Ganite Plus Standard Therapy in Patients with Relapsed/Refractory Lymphoma Presented at ASCO

...ted by patients who received the drug in clinical trials, concurrent use of Ganite with other potentially nephrotoxic drugs like aminoglycosides and amphotericin B may increase the risk for developing severe renal insufficiency in patients with cancer-relapsed hypercalcemia. If use of a potentially nephrotoxic...

Research on New Treatment for Neglected Disease Published in The New England Journal of Medicine

...tudy comparing Paromomycin, an aminoglycoside, and amphotericin B, the present standard of care in Bihar, India. Paromomycin was shown to be noninferior to amphotericin B with a final cure rate of 94.6% vs. 98.8% for am... of its administration (21 days versus 30 days for amphotericin B), its demonstrated safety and efficacy in pediat...
Amphotericin in Medical Products

Antibiotic Antimycotic Solution: 10,000 I.U. Penicillin, 10,000 g/mL Streptomycin, 25 g/mL Amphotericin B

Description: This combination of Penicillin, Steptomycin, and Amphotericin is effective against the most common forms of cell culture contamination; bacteria (gram positive and gram negative), yeast, and fungi; when used at a concentration of 10 mL/L. The sterile solution is a combination of all three antibioti...
Company:CellGro by Mediatech

Gibco Antibiotic-Antimycotic (100X), liquid

Description:...00 units of penicillin (base), 10,000 g of streptomycin (base), and 25 g of amphotericin B/ml utilizing penicillin G (sodium salt), streptomycin sulfate, and amphotericin B as Fungizone Antimycotic in 0.85% saline....
Company:Invitrogen
Amphotericin in Biological News

Singapore nanotechnology combats fatal brain infections

... nanoparticles are more powerful in inhibiting the growth of fungal infections than conventionally available anti-fungal drugs such as fluconazole and amphotericin B. "We are able to kill bacteria better than conventional antibiotics. By attacking the cellular structure of the microbes, our nanoparticles can ...

Gamma interferon could aid fight against fungal infections

...ed tissues but it has great potential to add to conventional therapy. When gamma interferon was given to mice infected with Cryptococcus along with amphotericin B, a standard antifungal treatment, the rate of cure was significantly higher than using one therapy alone. We need to look at the route of administra...

SinuNase Phase 3 show almost 100 percent of chronic sinusitis cases are from fungal-induced inflamma

...part of the Companys ongoing pivotal Phase 3 clinical trial for its lead pharmaceutical product, SinuNase, an intranasal formulation of the antifungal amphotericin B 0.01% suspension. In order to be enrolled in the clinical trial, patients must have had well-documented CS based on a history of the requisite symp...
Amphotericin in Biological Technology

FDA Clears Caspofungin (Cancidas(R)) Susceptibility Testing for TREK Sensititre(R) YeastOne(R) in Vitro Diagnostics (IVD) Product Line

... YeastOne for RUO -- TREK's standard RUO YeastOne plate (Part No. YO-9 * ) includes nine antimicrobics: anidulafungin, amphotericin B, caspofungin, fluconazole, 5 flucytosine, itraconazole, micafungin, posaconazole and voriconazole. *For research use only. Not for u...

Spherix Announces Full-Scale Production of Pharmaceutical Tagatose

...rlose as a novel and natural option to treat Type 2 diabetes." Inalco, a global supplier/producer of lactulose, 2-deoxy-D-ribose, ampicillin, and amphotericin B headquartered in Milan, Italy, becomes the second manufacturer to supply Spherix with D-tagatose. The new batch was entered into the current Phase ...

iCo Therapeutics Closes $1.3 Million Private Placement

...etic Macular Edema, iCo-008, a product with Phase II clinical history to be developed for severe ocular allergies, and iCo-009, an oral formulation of amphotericin B for sight and life - threatening diseases. iCo-009 also represents a new drug delivery technology with the potential to reprofile other parenteral a...

Prominent Physician Achieves Success Using Topical Sinus Medications via Pulsitile Irrigation

...medications accordingly. For fungal infections, he use antifungals (such as amphotericin B or Itraconazole). For inflammation, he adds an anti-inflammatory (such as... that are unstable and removes the need for preservatives. Note that we add amphotericin B to saline. This is fine as long as the mix is used right away before it p...

AEterna Zentaris and Paladin Labs Complete Sale and Purchase of Miltefosine Rights

...avido(R) has been proven to be highly effective and less toxic than currently available treatments. Other currently available treatments are liposomal amphotericin (Ambisome(R)) and Paromomycin. About leishmaniasis Leishmaniasis is an infectious disease transmitted by the bite of the phlebotomine sandfly. The...

AEterna Zentaris and Paladin Labs Announce Sale and Purchase of Miltefosine Rights

...shmaniasis. Impavido(R) has been proven to be highly effective and less toxic than current therapies. Other current available treatments are liposomal amphotericin (Ambisome(R)) and Paromomycin. About leishmaniasis Leishmaniasis is an infectious disease transmitted by the bite of the phlebotomine sandfly. The...

Rapid hit confirmation and early hERG liability testing using the IonWorks HT system

...ma Cat. #T-5651), Rimcazole dihydrochloride (Tocris Cat. #1497); amphotericin (Sigma Cat. #A-4888), DMSO (Sigma Cat. # D-2650); Versene (Gibco...paration of antibiotic solution (IonWorks HT assay) Aliquots of amphotericin (5.0 0.3 mg) were pre-weighed and stored at 4C. Prior to cell p...
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