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Amphiregulin in Medical News

Measuring medicine: How new technologies could help doctors predict patient outcomes

...g well even if the tumor grows. Presence of amphiregulin autocrine-loop predicts sensitivity of EGFR wild t... cell carcinoma (HNSCC) cell lines. This so-called amphiregulin autocrine loop appears to predict response to the targeted therapies gefitinib and cetuximab. amphiregulin expression could, in fact, be a suitable biomarker...

A New Strategy to Control Breast Cancer

...e) acts like a “molecular scissors” that releases a pair of ligands, called amphiregulin and TGF-alpha, from the cell surface. These ligands activate EGFR. EG...short interfering RNAs (siRNAs) that silence the TACE gene, the shedding of amphiregulin and TGF-alpha ligands could effectively be blocked. This also resulte...

Tobacco smoke increases the levels of Cox 2.

...h factor receptor (EGFR). EGFR is a protein related to the growth of various forms of cancer. Oral mucosal cells exposed to tobacco smoke produce more amphiregulin and TGF-a. Both of these chemicals are responsible for triggering EGFR functions. The researchers from Weill Medical College of Cornell Universit...
Amphiregulin in Medical Technology

ImClone Systems Showcases Extensive Research and Development Program at the AACR Annual Meeting

...cascade inhibition.) -- Emerging biomarkers may serve as predictors of clinical response to ERBITUX. (#5670 Ford et al. Expression of epiregulin and amphiregulin and K-RAS mutation status may predict disease control in metastatic colorectal cancer patients treated with cetuximab (ERBITUX(R)); #5671 Lievre et al...
Amphiregulin in Biological Products

Rat Anti-Mouse Amphiregulin Monoclonal Antibody, Unconjugated, Clone 206220 from R&D Systems

Description: Mouse Amphiregulin MAb (Clone 206220)...
Company:R&D Systems
Amphiregulin in Biological Dictionary

Transformed phenotype

...ersal of the transformed phenotype . ... Thus, thymosin ß4 is a determinant of AdoMetDC-induced transformed phenotype and invasiveness. ... amphiregulin Contributes to the Transformed Phenotype of Human Hepatocellular Carcinoma Cells ... autocrine loop that contributes to the transformed phenoty...
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(Date:4/21/2014)... consider ways to ease prohibitions on marijuana, the public ... the past century may provide valuable lessons, according to ... legalized marijuana in Colorado and Washington for recreational uses ... to best allow the production, sales and the use ... social ills. , A new study published online by ...
(Date:4/20/2014)... type of cell in the lining of the bladder ... according to researchers at the Stanford University School of ... first to pinpoint the normal cell type that can ... first to show that most bladder cancers and their ... explains why many human bladder cancers recur after therapy. ...
(Date:4/18/2014)... University School of Medicine researchers have been awarded two-year ... Novo Nordisk announced this month. Of the 110 initial ... Biologics Science Forum Program, only four projects were funded, ... They are Jonathan Powell, M.D., Ph.D.; G. William Wong, ... Powell, a professor of oncology, will use his $500,000 ...
(Date:4/18/2014)... available in French . ... practice and regenerative medicine. A team led by Ludwik ... Paris Tech) and Didier Letourneur from the Laboratoire Recherche ... just demonstrated that the principle of adhesion by aqueous ... repair soft-tissue organs and tissues. This easy-to-use gluing method ...
(Date:4/17/2014)... pain relief targets that could be used to ... King,s College London made the discovery when researching ... of the body. , Dr Marzia Malcangio said: ... pain generation and our findings could help chemotherapy ... One potential side effect of some chemotherapy drugs ...
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(Date:4/21/2014)... lower cholesterol can reduce heart attack and stroke risk, ... save the vision of diabetics, scientists say. , In ... of niacin to decrease bad cholesterol levels and raise ... for these patients, said Dr. Pamela Martin, biochemist at ... , Martin is Principal Investigator on a new ...
(Date:4/20/2014)... 20, 2014) A team of researchers from ... College, and Brandeis University has devised a wholly ... involving the so-called retromer protein complex. Retromer plays ... protein (APP) away from a region of the ... toxic byproduct amyloid-beta, which is thought to contribute ...
(Date:4/20/2014)... Although doctors have long known that people with Down ... leukemia (ALL) during childhood, they haven,t been able to ... Institute investigators has uncovered a connection between the two ... the journal Nature Genetics , the researchers track ... abnormality in Down syndrome to the cellular havoc that ...
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