Run Amok Enzyme Causes Same Problems in Both Humans and Fruit Flies
An enzyme found at elevated levels in several human cancers has been linked to abnormal tumor growth in fruit flies//, a discovery that provides a new model for understanding the link between stem cell biology and cancer, according to researchers.
Using fluorescent staining and laser-scanning ...
Sinking Economy Hit Hard by Soaring Healthcare Costs, Says MedicareSupplementPlans.com
... Los Angeles, CA (Vocus) August 7, 2009 -- Medicare and Medicaid costs are overwhelming government budgets as insurance costs run amok
and further sideline a failing economy, according to President Obama.
A February report by the Department of Health and Human Services indicates ...
Researchers led by Penn vet uncover the delicate protein balance behind the immune system response
...dicine has identified the protein interactions involved in the immune system process that fights infection yet, in certain inflammatory diseases, runs amok
and attacks friendly tissue.
The Penn team, led by Christopher Hunter, chair of the Department of Pathobiology at Penn Vet, has identified the pathw...
St. Jude finds molecule that could improve cancer vaccines and therapy for other diseases
... Investigators at St. Jude Children's Research Hospital have discovered a new signaling molecule that prevents immune responses from running amok
and damaging the body. The finding could lead to the development of new treatments for cancer, using vaccines; for autoimmune diseases, such as Type 1...
Molecular probe 'paints' cancer cells in living animals, Stanford researchers find
...atment of cancer and other diseases.
The probe's main ingredient is a molecule that labels active proteases - protein-destroying enzymes - that run amok
in cancerous cells. The molecule is normally invisible to the naked eye but it carries a fluorescent tag that lights up when it binds to the protease....
Scientists Spot Brain's 'Free Will' Center
...on't,' the inhibition of response," Masur explained. "The difference between us as intelligent ordered social creatures and the society that would run amok
is the ability to inhibit our responses, the ability to take control if a situation calls for it, to stop acting in a particular way . . . Maybe dow...
New and unique treatment for Psoriasis patients
...e. This unique drug targets renegade immune cells to control hard-to-treat psoriasis. Psoriasis has been thought to occur when the immune system goes amok
and cells called memory effector T cells prompt skin inflammation. The treatments that are currently available for psoriasis range from ointments to u...
CSHL researchers map changing epigenetic modifications that enable transposons to run amok
Cold Spring Harbor, N.Y. Much like cancer cells, plant cells grown for a long time outside of their normal milieu, in culture dishes, have highly unstable genomes. Changes in gene activity, or how genes are "expressed," help cells cope with challenging culture conditions but inadvertently also le...
New regulatory mechanism discovered for cell identify and behavior in forming organs
...inhibited by the modulating protein Sfrp5 (Secreted Frizzled Related Protein), a known antagonist of Wnt. Without this restriction, Wnt signaling runs amok
and the frog's foregut, liver and pancreas form improperly from a cascade of disorganized cell growth.
"We point out that Wnt has two key roles he...
Eli and Edythe L. Broad make unprecedented gift to endow Broad Institute of Harvard & MIT
...in regenerative medicine;
Harnessing the power of proteomics and genomics to understand how cells generate and use energy and how the process runs amok
in a multitude of diseases;
Applying genomic tools to key human pathogens, such as malaria and tuberculosis, aimed at transforming how these kille...
Distinguishing friend from foe in the battle against cancer
... The latest generation of cancer chemotherapeutic drugs specifically targets mutant enzymes or "oncoproteins" that have run amok
and now promote uncontrolled cell growth. As promising as these drugs are, cancer cells with their backs against the wall have the tendency to fight b...