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Ammonia in Medical News

BioMarin Announces Second Quarter 2009 Financial Results

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in development for the treatment of PKU and GALNS (N-acetylgalactosamine 6-sulfatase), which is currently in Phase I/II cli...

Patents Issued Covering Stable Tablet Formulation and Once Daily Dosing Regimen for Kuvan

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in development for the treatment of PKU and GALNS (N-acetylgalactosamine 6-sulfatase), which is currently in Phase I/II cli...

Patient Enrollment Complete for Phase I/II Clinical Trial for GALNS for Morquio A Syndrome

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase I clinical development for the treatment of PKU. For additional information, please visit www.BMRN.com. Informatio...

BioMarin to Host Second Quarter 2009 Financial Results Conference Call and Webcast on Thursday, July 30 at 5:00 p.m. ET (23:00 CET)

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is in clinical development for the treatment of PKU and GALNS (N-acetylgalactosamine 6-sulfatase), which is currently in Phase 1/2 clini...

Hyperion Therapeutics Raises $60 Million Series C

...tive pathway to the urea cycle for the disposal of ammonia through the renal excretion of phenylacetylglutami...sorders can cause dangerously heightened levels of ammonia in the bloodstream (hyperammonemia) resulting in b...the brain is exposed to gut-derived toxins such as ammonia that are normally removed from the blood by a heal...

Popular Jellyfish Sting Treatment Also Proven Effective on Stings From Portuguese Man-of-War

...ying Jellyfish Squish(TM) on a Portuguese man-of-war paralyzes the unfired nematocysts, preventing them from continuing to fire their toxins. Vinegar, ammonia and other products tested did not paralyze the nematocysts and actually caused the remaining nematocysts to fire. Jellyfish Squish founder J.C...
Ammonia in Medical Technology

Hyperion Therapeutics Receives Orphan Drug Designation for HPN-100 for the Treatment of Urea Cycle Disorders

... untreated, urea cycle disorders can cause dangerously heightened levels of ammonia in the bloodstream (hyperammonemia) resulting in brain damage, coma, and/or...aloperidol, or steroids as these drugs have been reported to increase blood ammonia levels, and probenecid may affect the kidneys' excretion. Use with great ca...

BioMarin Initiates Phase 1/2 Clinical Trial for GALNS for Morquio A Syndrome

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase 1 clinical development for the treatment of PKU. For additional information, please visit www.BMRN.com . Informat...

Hyperion Therapeutics Announces Results for Phase II Study in Urea Cycle Disorders

...he abstract is entitled " Phase 2 Study of A Novel ammonia Scavenging Agent In Adults With Urea Cycle Disorde...d on their stable dose of BUPHENYL and 24-hour PK, ammonia measurements, amino acids, and urine collections w... No SAEs occurred during 100% HPN-100 treatment. ammonia values were ~30% lower on HPN-100 assessed as TNAU...

Hyperion Therapeutics Completes Enrollment in Phase 1/2 Clinical Trial in Patients With Urea Cycle Disorders

...e disorder. Left untreated, UCDs can cause dangerously heightened levels of ammonia in the bloodstream (hyperammonemia) resulting in brain damage, coma, and/or...aloperidol, or steroids as these drugs have been reported to increase blood ammonia levels, and probenecid may affect the kidneys' excretion. Use with great ca...

BioMarin Initiates Phase 1 Clinical Study of PEG-PAL in PKU

... the Phase 1 clinical study of PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase) for the treatment of phenylketonuria (PKU). The study is expected to...ts with PKU. About PEG-PAL PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase) is an investigational enzyme substitution therapy for the treatment ...

Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment

...yl sulfide; and nitrogen-containing compounds including ammonia, methyl amines, methyl pyrazines, skatoles and indoles. It is also recognized that ammonia emissions from livestock contribute significantly to the eutrophication and acidification of soil and water. Some level of nutrient overload occurs na...
Ammonia in Medical Products

Infinity™ Ammonia

Description: The Infinity Ammonia single liquid stable reagent is intended for the in vitro quantitative determination of Ammonia in plasma. Infinity Ammonia reagent patented formulation not only provides excellent stability and convenience but ensures excellent precision and correlation against existing as...
Company:ThermoFisher Scientific

Ammonia (NH3)

Description:... For the quantitative in vitro determination of ammonia in plasma...
Company:Randox Laboratories Ltd.

Ammonia/Alcohol Control

Description:... Ammonia/Alcohol Control is intended as a means of monitoring various ammonia and ethanol assay methods. This ready-to-use, three-level control is targeted at clinically significant levels of ammonia and alcohol. Assay values are provided for the following instruments: AU Se...
Company:Quantimetrix Corporation

Pyrex brand blood chemistry (Ostwald-Folin) pipette, color-coded, Class A

Description:... The short and compact design makes this pipette useful for total nitrogen determination, urea and ammonia in urine, and blood serum tests. They are calibrated "To Deliver" by blowing out the last drop. Comp Dim: L 275 mm Color: orange Measur range: volume...
Company:Sigma-Aldrich

Liquichek Ethanol/Ammonia Control

Description:... Liquichek™ Ethanol/Ammonia Control is a liquid product used to monitor ethanol and ammonia test procedures in the clinical laboratory....
Company:Bio-Rad Laboratories

Ammonia Standard

Description:... Intended for the quantitative determination of ammonia in plasma. Two vials, dry powder reagents. Method: Enzymatic, alphaketoglutarate. Uses NADPH to eliminate interferences from other plasma compounds. R...
Company:Hemagen Diagnostics, Inc.

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Ammonia in Medical Definition

Tincture

...Camphorated opium tincture ( paregoric ) An herbal extract The multiple plant extract Iberogast Examples of spirits include: Spirit of ammonia (also called spirit of hartshorn ) Spirit of camphor Spirit of ether, a solution of diethyl ether in alcohol "Spirit of Mindererus", ammo...
Ammonia in Medical Dictionary

Ammonia

Ammonia is a compound of nitrogen and hydrogen with the formula NH3. It is normally encountered as a gas with a characteristic pungent odor. Ammonia contributes significantly to the nutritional needs of terrestrial organisms... ammonia n. A colorless, pungent gas, NH 3 , extensively used ...

Urea Cycle

...cal reactions occurring in many animals that produces urea (NH2)2CO from ammonia (NH3). This cycle was the first metabolic cycle discovered . In mamm...f one of the enzymes in the urea cycle which is responsible for removing ammonia from the blood stream. The urea cycle involves a... urea cycle ...

Helicobacter pylori

...ter pylori (he-lick-oh-back-ter pie-lorrie) is an unusual name that ... Once Helicobacter pylori invades your stomach lining, it produces an ammonia ... HELICOBACTER PYLORI OVERVIEW Helicobacter pylori , also known as H. pylori , is a ... Management of duodenal ulcers in patients i...

Caustic

...rs. Find a reliable & professional Caustic manufacturer or supplier. ... Caustic Soda (20557) Potassium Hydroxide (84) Aluminium Hydroxide (2) ammonia (1) ... Find Caustic Resin and more Music at Shopping.com. Shop 1000's of stores and compare prices. Free shipping on all items. Compare pri...
Ammonia in Biological News

Seabird ammonia emissions contribute to atmospheric acidity

Amsterdam, September 23, 2008 Ammonia emissions from seabirds have been shown to be a significant source of nitrogen in remote coastal ecosystems, contributing to nutrient enrichment (eutrophication) and acidification in ecosystems. While most ammonia emissions originate from domesticated animals...

Study highlights massive imbalances in global fertilizer use

...en runoff from farms has contaminated surface and groundwater and helped create massive "dead zones" in coastal areas, such as the Gulf of Mexico. And ammonia from fertilized cropland has become a major source of air pollution, while emissions of nitrous oxide form a potent greenhouse gas. These and...

Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii

...ose that may be damaged by the presence of oxygen. A. vinelandii lives in soil and has the ability to convert nitrogen from the atmosphere into ammonia via bacterial enzymes called nitrogenases. Nitrogen fixation is essential for life since different nitrogen-containing molecules are used to produce D...

Glutamine supplements show promise in treating stomach ulcers

...Our work demonstrated that the damaging effects of ammonia on gastric cells could be reversed completely by t...amine," explains Hagen. "The amino acid stimulated ammonia detoxification in the stomach as it does in the liver so that the effective concentration of ammonia was reduced, thereby blocking cell damage." She...

Illinois Soil Nitrogen Test measures microbial nitrogen

...ogen fertilizers are to be used efficiently. The Illinois Soil Nitrogen Test (ISNT) was developed for this purpose, and involves estimation of gaseous ammonia liberated by heating the soil with strong alkali in a Mason jar. Several studies have provided evidence that the ISNT is predictive of yield response ...

Ocera Therapeutics licenses novel treatment for acute hepatic encephalopathy from UCLB

...des a study which demonstrated an acute and sustained reduction of systemic ammonia levels as well as decreased intracranial pressure in models of AHE in acute...ilure and cirrhosis. With severe liver impairment, toxic substances such as ammonia that are normally removed by the liver accumulate in the blood and impair t...
Ammonia in Biological Technology

New clues about a hydrogen fuel catalyst

...d other atoms. The catalyst chemically reacts with ammonia borane, a molecule that stores hydrogen densely, t...olecule that contains hydrogen atoms, in this case ammonia borane, serves as a sort of structural support. The catalyst plucks the hydrogen from the ammonia borane as needed to run the device. The PNNL c...

Helix BioPharma to Present L-DOS47 Analytical Method Development Findings at 2009 AAPS National Biotechnology Conference

...reverses the urea cycle by breaking down urea into metabolites that include ammonia and hydroxyl ions. By doing so at the site of cancerous tissues in the body... to be necessary for cancer cell survival. As well, the local production of ammonia at the site of cancerous tissues is thought to readily diffuse into the can...

Kuvan Receives Priority Review Status From Health Canada

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is in clinical development for the treatment of PKU and GALNS (N-acetylgalactosamine 6-sulfatase), which is currently in Phase 1/2 clini...

BioMarin to Present at the Jefferies Healthcare Conference

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase I clinical development for the treatment of PKU and GALNS (N-acetylgalactosamine 6-sulfatase), which is currently ...

Proplant Awarded Qatar Project

...y it has been awarded an EPC contract by Qatar Fertiliser Company for their ammonia and urea plants Steam Integration Project. QAFCO operates the world's largest single site fertilizer complex with four ammonia and urea plants. Proplant will perform engineering, procurement and constr...

BioMarin to Present at the Goldman Sachs Healthcare Conference

...rship with Merck Serono, a division of Merck KGaA of Darmstadt, Germany. Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase I clinical development for the treatment of PKU and GALNS (N-acetylgalactosamine 6-sulfatase), which is currently ...
Ammonia in Biological Products

DNA120 OP SpeedVac System from Thermo Scientific

Description:...c oligos. Its sturdy design incorporates a glass cover and a post-trap with ammonia neutralizing solution for fully automated, unattended, odor-free processing... Comes standard with a glass lid for improved chemical resistance and ammonia post trap Dual Digital Timers for independent control of RUN and HEA...
Company:Thermo Scientific
Ammonia in Biological Definition

Amine

... ammonia Amines are organic compounds containing nit...ctional group. Amines have structures resembling ammonia , where one or more hydrogen atoms are replaced ...e following pictures, if only one the hydrogens in ammonia is replaced by a carbon based group, then it is a ...

Bacterium

...o kill bacteria or other pathogens to prevent contamination and risk of infection. In soil, microorganisms help in the transformation of nitrogen to ammonia with enzymes secreted by these microbes, which reside in the rhizosphere (a zone that includes the root surface and the soil that adheres to the roo...

Carbohydrate

...xicity . The brain can only utilize carbohydrates for energy, and protein may not supply enough in many cases. The increase in protein means that more ammonia groups need to be removed from the blood. Catabolism There are three metabolic pathways of carbohydrate catabolism : glycolysis c...

Enzyme

... enzymes which transfer phosphate groups to a tyrosine residue in a protein Tyrosinase Urease : hydrolizes urea into carbon dioxide and ammonia Xanthine oxidase : oxidizes hypoxanthine to xanthine and further to uric acid Purification Since enzymes are proteins , enzyme puri...

Bacterium

...o kill bacteria or other pathogens to prevent contamination and risk of infection. In soil, microorganisms help in the transformation of nitrogen to ammonia with enzymes secreted by these microbes, which reside in the rhizosphere (a zone that includes the root surface and the soil that adheres to the roo...

Liver

...l as protein C , protein S and antithrombin . The liver neutralizes toxins , most medicinal products, and hemoglobin . The liver converts ammonia to urea . The liver stores of a multitude of substances, including glucose in the form of glycogen, vitamin B12 , iron , and copper . In th...
Ammonia in Biological Dictionary

Urea cycle

...l reactions occurring in many animals that produces urea (NH2)2CO from ammonia (NH3). This cycle was the first metabolic cycle discovered . In mammals... one of the enzymes in the urea cycle which is responsible for removing ammonia from the blood stream. The urea cycle involves a... urea cycle n. ...

Urea

... compound to be synthesized ... Synthetic urea is created from synthetic ammonia and carbon ... Urea is a nitrogen-based waste product secreted by the ...ions. ... The commercial synthesis of urea involves the combination of ammonia and carbon ... Urea -formaldehyde resin is created when the two (2) compon...

Deamination

...r nitrogenous waste comes from the breakdown of amino acids. This occurs by deamination . Deamination of amino acids results in the production of ammonia (NH3) ... Information on EC 3.8.1.8 - atrazine chlorohydrolase ... deamination . 687391. 0.02. 2-(N-ethylamino)-4-hydroxy -6-(N-isopropylamino)-1,...

Decomposers

... in the form of dead wood, leaf litter, plant ... ... is carried out mainly by bacterial and fungal decomposers . ... present to detoxify the ammonia produced by the fish and decomposers in the tank. ... Decomposers . Kenny Hood's ... DECOMPOSERS in the food chain. So hard to see ... DECO...

Collecting tubules

...sts of portions of the loops of Henle and the collecting tubules . ... Collecting tubules are not considered part of the nephron; ... ... of ammonia were examined in rabbit cortical collecting tubules perfused in vitro. ... restricted diffusion in the collecting tubules ; this may account ...

Autotrophic

...utotrophic ) and animals (heterotrophic) organisms, ... Autotrophic vs. Heterotrophic Bacteria. Fritz Industries. There's a lot of ... level of ammonia conversion that is attained by true autotrophic nitrifiers. ... ... development, whereas it is autotrophic , when its source of carbon ... Au...
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