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Amikacin in Medical News

Royer Animal Health Enters Into Exclusive Agreement With MWI Veterinary Supply for U.S. Distribution of Next-Generation Therapeutics to Treat Cancer and Infections

...erapy." R-GEL ANTIBIOTIC WOUND DRESSING, is a timed-release antibiotic gel that solidifies in situ. It provides a sustained therapeutic dose of amikacin and clindamycin at the site of administration for a period of 7-9 days. The R-GEL matrix is biodegradable and fully resorbed in about 4 weeks. R-GEL h...

Transave Completes Enrollment in Arikace(TM) Phase II Bronchiectasis Study

...he safety and efficacy of Arikace(TM) (liposomal amikacin for inhalation) in non-cystic fibrosis (CF) bronch...ns in the U.S. About Arikace (liposomal amikacin for inhalation) Arikace is a form of the...monary liposome technology prolongs the release of amikacin in the lungs while minimizing systemic exposure. T...
Amikacin in Medical Technology

Clinical Trial Data (Phase 2a) Regarding Inhaled Amikacin Will Be Presented at American Thoracic Society International Conference

SAN FRANCISCO--(BUSINESS WIRE)--May 9, 2007 - Results of a Phase 2a clinical trial evaluating the potential of NKTR-061 (inhaled amikacin) to treat hospital acquired gram-negative bacterial pneumonia will be presented at the American Thoracic Society (ATS) International Conference, May 18 - 23, 200...

Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)

...d to Transave Inc., for the continued development of ARIKACE(TM) (liposomal amikacin for inhalation), an antibiotic that aims to treat Pseudomonas lung infect...osomes. This advanced pulmonary liposome technology prolongs the release of amikacin in the lungs while minimizing systemic exposure. The treatment uses biocomp...

Mpex Pharmaceuticals Presents New Data on MP-376 in Cystic Fibrosis

...atients were at least 4-fold lower than those obtained for tobramycin, amikacin and aztreonam. -- Spectrum: MIC90s for MP-376 against clinical isolates ...sed less than two fold under anaerobic conditions, whereas tobramycin, amikacin and aztreonam treated isolates increased 4-7 fold under anaerobic cond...

Transave Announces Positive Phase II Results for Once-Daily Arikace(TM) in the Treatment of Cystic Fibrosis Patients Who Have Pseudomonas Lung Infections

... lead investigational drug, Arikace(TM) (liposomal amikacin for inhalation). The compound is being developed f... a Phase III trial. "This formulation of liposomal amikacin was specifically designed for sustained release an... results support the potential value of delivering amikacin through Transave's next-generation liposomal techn...

Amikacin Inhale Shows Promising Results in Phase II Study

... without reaching high systemic concentrations." amikacin Inhale is a unique drug-device combination, being ...iquid formulation of the aminoglycoside antibiotic amikacin with Nektar Therapeutics' proprietary Liquid Pulmonary Technology (LPT(TM)), designed to deliver amikacin deep into the infected lungs. The device can be ...

Nektar Therapeutics to Present Positive Data at Upcoming Medical and Scientific Meetings

...n pneumonic portions of lung" Poster #517: "Evidence of High amikacin Lung Deposition in Mechanically Ventilated Patients (MVP) with Pneum... Subjects (HS) dosed using NKTR-061" Poster #518: "High in vivo amikacin lung deposition after NKTR-061 dosing correlates with in vitro aeros...

Nektar Threraputics Announces Phase 2a Clinical Results Regarding the use of NKTR-061 (Inhaled Amikacin) to Treat Gram-Negative Hospital-Acquired Pneumonia Presented at the Annual American Thoracic Society International Conference

... www.nektar.com: -0- -- Poster Board #710: amikacin Aerosol Achieves High Epithelial Lining F... alveoli. Objective: Evaluate aerosol amikacin (AMK) penetration into the epithelial lun... -0- -- Poster Board #718 Inhaled amikacin Reduces IV Antibiotic Use in Intubated Me...
Amikacin in Biological News

Clues to gene expression in cystic fibrosis will guide research

...al drug option, as it may cause serious side effects for some patients, including ear and kidney damage. The authors suggest that other drugs, such as amikacin or PTC124, with a comparable mode of action and fewer side effects, may have treatment potential. The in vitro method used to predict the trial’s out...
Amikacin in Biological Technology

Nektar Sells Pulmonary Business to Novartis For $115 Million and Nektar Retains Key Pulmonary Programs Including Amikacin Inhale, Inhaled Vancomycin, and Ciprofloxacin Inhalation Powder

SAN CARLOS, Calif., Oct. 21 /PRNewswire-FirstCall/ -- (11:00 PM PT, Oct. 20) -- Nektar Therapeutics (Nasdaq: NKTR ) today announced that Novartis AG has agreed to acquire from Nektar specific pulmonary delivery assets, technology, and intellectual property for $115 million in cash. "This ag...

Transave Enters Into Cooperative Research Agreement With NIH To Study ARIKACE(TM) In Nontuberculous Mycobacteria

...of the National Institutes of Health (NIH), to study ARIKACE(TM) (liposomal amikacin for inhalation) in patients with nontuberculous mycobacteria (NTM) lung inf...somes. This advanced pulmonary liposome technology prolongs the release of amikacin in the lungs while minimizing systemic exposure. The treatment uses biocom...

Transave, Inc. Secures $12.5 Million in New Financing

...d positive Phase II data on Arikace(TM) (liposomal amikacin for inhalation) from a randomized, placebo-control...h and quality of life." About Arikace (liposomal amikacin for inhalation) Arikace is a form of the antibiotic amikacin that is enclosed in nanocapsules of lipid called l...

Transave, Inc. Raises $35 Million Through Series D Convertible Preferred Stock Financing

...our lead clinical compound, ARIKACE(TM) (liposomal amikacin for inhalation). We are on track to have Arikace P...rtible preferred stock. About ARIKACE (liposomal amikacin for inhalation) ARIKACE is a form of the antibiotic amikacin that is enclosed in nanocapsules of lipid called l...

Study Confirms Anti-Infective ARIKACE(TM) Effectively Penetrates Mucus and Biofilm, and Kills Pseudomonas, a Bacteria Plaguing Cystic Fibrosis Patients

... release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomanas aeruginosa lung infections,...Pseudomonas in the biofilm that trigger release of amikacin from the liposomes. These factors are expected to ...arget for antibiotics and the triggered release of amikacin resulted in what was essentially Pseudomonas suici...
Amikacin in Biological Definition

Antibiotic

...biotics . Classes There are many way to classify antibiotics. One such classification is by chemical structure: Aminoglycosides amikacin Dibekacin Gentamicin Kanamycin Neomycin Netilmicin Paromomycin Sisomycin Streptomycin Tobramycin ...
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