Neuronal 'traffic jam' marks early Alzheimer's disease
Early Alzheimer's disease may be precipitated by a "traffic jam" within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers. In mouse models of Alzheimer's disease and in human brain samples from people with the disease, researchers observed a characteristic breakdown in...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
Brain cells in a mouse model of Alzheimer'sdisease have surprised scientists with their ability to recuperateafter the disorder's characteristic brain plaques are removed.Researchers at Washington University School of Medicine in St. Louisinjected mice with an antibody for a key component of brain plaques,the amyloid beta (Abeta) peptide. In areas of the brain whereantibodies cleared plaque...Gene vaccine for Alzheimer's disease shows promising results
UT Southwestern Medical Center at Dallasresearchers have found a way of stimulating the immune systems of miceto fight against amyloid proteins that cause the devastating plaquesthat are characteristic of Alzheimer's disease.For years scientists have examined the possibility of using aprotein-based vaccine to slow the progression of the disease in itsearly stages. UT Southwestern researcher...Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease
To understand the formation of the brain-clogging deposits that cause such disorders as Alzheimer's and Parkinson's diseases, Duke University chemists have figured out how to capture and "micromanipulate" the single molecular building blocks of the deposits. Their aim is to understand the detailed assembly process for the toxic protein called amyloid plaque. Such basic understanding, they...Nanoscale Diagnostic Sets Sights on Alzheimer's
Using their novel bio-bar-code amplification (BCA) technology, researchers analyzing fluid from around the brain and spinal cord have detected a protein linked in recent studies to Alzheimer's disease. Gold nanoparticles and bio-bar codes bring sen...Northern BoundTM Human Alzheimer's Total RNA Blot from Sigma-Aldrich
Description:Blot includes 7 lanes of total RNA isolated from Alzheimer's-diseased brain tissue including: precentral gyrus, postcentral gyrus, frontal lobe, temporal lobe, parietal lobe, occipital lobe and cerebellum. Patent/trademark/license (electronic): Manufactured by BioChain, Inc....Membrane Protein - Alzheimer's Disease:Brain: Occipital Lobe from BioChain
Description:Membrane Proteins from over 50 different human Alzheimer, Diabetic, Liver Cirrhosis, and Lupus diseased tissues are available....Neurobiology of Alzheimer's Disease from Promega
Description:D. Dawbarn and S.J. Allen (1995) This book contains up to date reviews by world authorities on current issues relating to the aetiology and treatment for Alzheimer's disease. Several major advances have been made recently which greatly improve our understanding of this disease. Topics include molecular neuropathology through clinical and diagnostic aspects, the molecular nature of beta-amyloid...Total Protein - Alzheimer's Disease: Brain: Pons from BioChain
Description:Total Proteins from over 50 different human Alzheimer, Diabetic, Liver Cirrhosis, and Lupus diseased tissues are available....Alzheimer's drug developer lands $1.2M in venture funding
The latest round of funding brings the total equity capital raised in t...Biotech firm has strokes, Alzheimer's in its sights
Quincy Bioscience is based in Madison's University Research Park, but it derives its research sup...Mithridion wins grants for Alzheimer's research
The twin grants, awarded by the , a branch of t...Alzheimer's drug firm and more winners named in Wisconsin business-plan contest
Mithridion, a University of Wisconsin-Madison spinoff, emerged as an early favorite in the competit...Alzheimer's drug market to hit $5.5 billion by 2009, study says
Toronto-based Pharmaceutical manufacturers profiled in Millennium's study, entitled "Global Markets for Alzheimer's Disease Medications 2005," include Pfizer, Shire Pharmaceuticals and Nova...Evidence Links Protein Damage to Neurodegenerative diseases like Parkinson's and Alzheimer's
Neurodegenerative diseases - including Parkinson's, Alzheimer's, Diffuse Lewy body disease, and Multiple System Arophy - are collectively called synucleinopathies. Most commonly they become symptomatic due to a deficiency of a specific neurotransmitter - in the case of Parkinson's it is dopamine. When the neurons that produce these chemicals die or become impaired, which occurs with oxidation, th...Miracle cure for Alzheimer’s around the corner
Alzheimer’s Disease, one of the most common and perhaps the most dreadful kind of Dementia, where there is degeneration of the brain tissue, might at last have the much awaited miracle cure round the corner. A vaccine made headlines sometime ago, as being efficient in reducing plaque formation in mice, which is characteristic of Alzheimer’s. Latest reports say that it also improves mental...Vaccine for Alzheimer’s diseas
Researchers developing a vaccine against Alzheimer’s disease have shown that it seems to stop mice with the condition losing their memory. The results boost hopes that such vaccines could delay or prevent similar symptoms in people. The vaccines reduces the build-up of protein deposits in mouse brains -the other major indicator of Alzheimer’s diseases. The pharmaceutical company Elan,...Decrease in testosterone levels lead to Alzheimer's
Suppression of testosterone levels in men with testicular cancer may inadvertently increase the risk of Alzheimer’s disease, warn US researchers.A research team from North Carolina University has found that when circulating testosterone levels go down, a high rise in levels of amyloid – the protein implicated in Alzheimer’s disease – occurs. They suggest that this phenomenon might explain why...Samaritan's Alzheimer's Drug Caprospinol Suggests Brain May be Able to Heal From Alzheimer's Disease
Animal Study Confirms Caprospinol's (SP-233) Ability to Clear BrainPlaque and Empower Rat Brain Cells to Recover Memory Function In Vivo 'Proof of Concept' Study Proposes Direct CorrelationBetween Removing Beta Amyloid Plaque and Memory Recovery LAS VEGAS, July 10, 2007 (PRIME NEWSWIRE) -- SamaritanPharmaceuticals Inc. (AMEX:LIV), a developer of innovative drugs,is ple...