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Allopurinol in Medical News

New Report Just Published: World Multiple Myeloma Therapeutics Market Report

...ultiple Myeloma II-42 Ortho Biotech Files Application with FDA for Approval of Combination Drug DOXIL(R) and VELCADE(R) II-43 Caraco's allopurinol Receives FDA Approval II-43 FDA Approves Thalomid(R) as Combination Therapy for Multiple Myeloma II-43 Revlimid(R) Obtains Regulatory Appr...

FDA approves ULORIC (febuxostat) for the chronic management of hyperuricemia in patients with gout

...some for up to five years. The largest, pivotal, phase 3 clinical trial, CONFIRMS, demonstrated that ULORIC 80 mg was superior to ULORIC 40 mg and allopurinol 300/200 mg (67 percent, 45 percent and 42 percent, respectively) at achieving the primary end point of serum uric acid less than 6.0 mg/dL at the fina...

Pegloticase BLA Filing Accepted for Priority Review by FDA

...rum uric acid and whose signs and symptoms are inadequately controlled with allopurinol at the maximum medically appropriate dose or for whom allopurinol is contraindicated. ABOUT PEGLOTICASE Pegloticase (formerly referr...

Studies examine treatment for gout and the condition's protective effects

...hree dosage levels of febuxostat once daily; allopurinol; or a placebo. The allopurinol dose given was based on kidney function; those with normal function receive...e none of the patients with renal impairment who received the lower dose of allopurinol reached it. During the first eight weeks, more patients receiving febuxosta...

Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to Market Generic Version of Zyloprim(R)

...pany's Abbreviated New Drug Application (ANDA) for allopurinol Tablets USP, 100 mg and 300 mg (Allopurinol). allopurinol is indicated in the management of patients with si...aily uric acid excretion are elevated. Our generic allopurinol is the bioequivalent to Zyloprim(R), a registered ...

Clinical Trials of New Drug Febuxostat Show Promise in Gout Treatment

...inol. The study participants were either given allopurinol or febuxostat (two different doses) as a form of t...uce plasma uric acid levels by as much as 6 mg/dl. allopurinol treatment was taken by 21% of the members, followe...as found that the new drug was more effective than allopurinol when used for more than a year, as revealed by sta...
Allopurinol in Medical Technology

Phase III Trial Results Show Elitek(R) (rasburicase) Significantly Reduced Plasma Uric Acid Levels versus Allopurinol in Adults with Hematologic Cancers at Risk for Tumor Lysis Syndrome

- Results Presented at ASH Annual Meeting- SAN FRANCISCO, Dec. 6 /PRNewswire-FirstCall/ -- Sanofi-aventis today announced results of a randomized phase III study presented at the 50th Annual Meeting of the American Society of Hematology. The study in adult patients with hematological mali...

New Study Shows PCR and FCR Have Significant Activity in B-cell Chronic Lymphocytic Leukemia

... Hematologic Malignancies Jeffrey Matous, M.D., Rocky Mountain Cancer Centers-Midtown: Superiority of Rasuburicase vs. allopurinol on serum uric acid control in adult patients with hematologic malignancies at risk of developing Tumor Lysis Syndrome Multip...

Ardea Biosciences, Inc. Announces New Clinical Development Program Directed Toward the Treatment of Gout

...roved pharmaceutical agent, allopurinol, has significant limitations. According to a large, randomized, clinical study, only 21% of patients receiving allopurinol achieve their treatment target, while 8% experienced serious adverse events (1). Hyperuricemia in HIV There is a high prevalence of hyperuricemia ...

Savient Pharmaceuticals Announces Acceptance of Two Gout-Related Abstracts for Poster Presentation at the European League Against Rheumatism (EULAR) 2007 Annual Congress

...d quality of life and physical functioning to the assessment of patient-reported outcomes in treatment-failure gout (defined as gout patients for whom allopurinol is contraindicated or is ineffective). In addition to the two abstracts accepted for poster presentation, two additional abstracts have been acce...
Allopurinol in Biological Technology

The Law Offices of Brian D. Witzer Wins 6+ Million Dollar Verdict

...had gout and described pain in her toe consistent with gout. He prescribed allopurinol in order to prevent a recurrence of an acute gout attack. Plaintiff made a...nosis and monitoring for an adverse reaction were needed before prescribing allopurinol to my client." stated Brian D. Witzer, principal of the law firm. "Had the ...

FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout

..., CONFIRMS, demonstrated that ULORIC 80 mg was superior to ULORIC 40 mg and allopurinol 300/200 mg (67 percent, 45 percent and 42 percent, respectively) at achievi... observed in patients treated with ULORIC (0.74 per 100 patient-years) than allopurinol (0.60 per 100 patient-years) in clinical trials. A causal relationship with...
Allopurinol in Biological Dictionary

Uric acid

...ns is associated with elevated blood levels of uric acid . ... (Redirected from Uric acid nephrolithiasis) Jump to: navigation, search " ... allopurinol interferes with the liver's production of uric acid . ... Oxypurines (like xanthine, hypoxanthine, uric acid , and allantoin – words with ......
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