Star Scientific Reports on Filing Patent Application for Zero-Nitrosamine Tobacco Curing Process, Product Development by Rock Creek Pharmaceuticals
...Creek is exploring processes for the extraction of alkaloids
from zero-nitrosamine tobacco for the purpose of using those alkaloids
in the development of a generic nicotine replaceme...entific previously obtained for the use of tobacco alkaloids
in treating various neurological conditions, inclu...
Screening the herbal pharmacy
...reast cancer treatment are made from yew trees. The popular periwinkle plant, which grows along the ground of many front yards, is the source of vinca alkaloids
that are effective, for example, against malignant lymphomas. The modern anti-cancer drugs topotecan and irinotecan are derived from a constituent of ...
New IDSA Clinical Practice Guidelines Recommend NOXAFIL(R) (Posaconazole) for Antifungal Prophylaxis in Certain High-Risk Patients
...lasma concentrations of these medicinal
products, leading to QTc prolongation and rare occurrences of torsades de
pointes. Coadministration with ergot alkaloids
is also contraindicated.
Serious and rare fatal toxicity from cyclosporine has occurred when
taken in combination with NOXAFIL and therefore reducti...
They were right after all
...al synthesis was strongly challenged and was even dismissed as a myth by Gilbert Stork (Columbia University) in 2001.
Quinine and the cinchona bark alkaloids
play an important role in modern medicine. It is thus amazing that no attempts to reproduce the RabeKindler conversion of quinotoxine into quinine hav...
New treatment option studied for bladder cancer
...determine if those patients can benefit from vinflunine, which is in the same vinca alkaloid family as Navelbine, used for lung cancer.
These vinca alkaloids
keep cells from dividing properly so the tumor cant grow and existing tumor regresses, says Dr. Coleman, a principal investigator on the study sponsor...
Beware Weight Loss Drugs, Say Canadian Experts
...s supplements in the early 2000s relied on chemicals in a shrub native to China and Mongolia. Ephedra sinica, or Ma huang in Chinese, contains ephedra alkaloids
that, when combined with caffeine, caused weight loss.
Consumers clamoured for the heavily advertised supplement, but scientists only found ou...
Migraine in women
...en migraines are expected to occur.
Medications used in the prevention of menstrual migraine include nonsteroidal anti-inflammatory drugs, ergots, alkaloids
and triptans. Medications used in the prevention of other migraines also are effective in preventing menstrual migraine. In some patients, menstrual m...
Medication Abuse In Chronic Migraine May Cause Hormonal Abnormalities
The lab research had shown that the drugs used to treat migraine attacks including certain non-steroidal anti-inflammatory drugs (NSAIDs), ergot alkaloids
and triptans may change the body's secretion of hormones such as growth hormone and the stress hormone cortisol.
Keeping this in mind Rainero an...
Weight loss supplements harm the body
...r a combination of two supplements. Xenadrine RFA contained 25.4 mg ephedra alkaloids
and 85 mg caffeine. The other contained 23.2 mg ephedra alkaloids
and guarana containing 167 mg caffeine.
The results revealed that repe...
Alkaloids in Medical Technology
EntreMed Presents Mechanism Data for Its Three Lead Oncology
...liquid tumors. There are three drug binding sites on
tubulin: the vinca binding domain, the taxol- binding site and
colchicine-binding site. The vinca alkaloids
microtubules. The taxanes bind to the taxol-binding site and
stabilize microtubules. While vincas and taxanes are widely used
ZIOPHARM Presents Unique Mechanism Data for Indibulin at AACR
...wth at the G2/M phase. Microtubulins are
well-established targets for anti-cancer drug development and
tubulin-binding drugs such as taxanes and Vinca alkaloids
currently widely used to treat cancer. Indibulin is in a phase I
dose-ranging and safety study in Europe. The Company expects to
begin phase I/II ...
Alkaloids in Medical Products
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Alkaloids in Biological News
American Chemical Society's Weekly PressPac -- June 3, 2009
...darts for hunting.
Frogs get nearly all of the alkaloids
from their diet, removing alkaloids
from ants, mites, small beetles, millipedes and po...in the frogs' own bodies. Feeding experiments with alkaloids
fed to captive frogs are planned, which might sett...
American Chemical Society's weekly PressPac -- April 29, 2009
...-scale outbreaks of fires, and have high levels of alkaloids
in their needles. Fires help to transfer alkaloids
from needles into tiny particles that can be then transported through the air. Noting that the alkaloids
can be transported long distances, the scientists ...
Potentially harmful chemicals found in forest fire smoke
Finding these toxins -- known as alkaloids
-- helps researchers understand how they cycle through earth and air. Smoke-related alkaloids
in the environment can change aquatic and terrestr...r. Researchers have long suspected the presence of alkaloids
in smoke or detected them in air during fire seaso...
Growing fuel and medicine: Advancing biofuels and plant-produced therapeutics
...a J. Weathers, PhD Professor, Department of Biology and Biotechnology, WPI
Plants naturally produce many valuable small molecules like terpenes and alkaloids
that have for centuries been used in treatment of disease and as pesticides. More recently plants have also been proposed as suitable production vehic...
Caltech engineers build mini drug-producing biofactories in yeast
...'t normally exist in nature.
"If one thinks of these molecules as encoding functions that are of interest to us, the ability to produce nonnatural alkaloids
will provide access to more diverse functions and activities. By expanding to nonnatural alkaloids, we can search for molecules that provide enhanced ...
The secret behind silkworm's hardy stomachs
...silkworms contain a special digestive enzyme that is not affected by mulberrys toxic chemicals.
Mulberry leaves contain an extremely high amount of alkaloids
that inhibit enzymes that break down sucrose (sugar), and thus are potentially quite toxic. However, one type of sucrase called beta-fructofuranosidas...
Bitter orange SRMs: Tools for product analysis/quality
...terials for analysis and measurement come with certified concentration values for synephrine, octopamine, tyramine, N-methylytramine, hordenine, total alkaloids
Ayurvedic nightshade deadly for dengue mosquito
...roduce two types of phytochemicals. says Chandra. The most interesting are the secondary phytochemicals, such as steroids, terpenoids, flavonoids and alkaloids
these act as a repellent which protect against the lethal effects of the larval mosquitoes.
A number of plants have been reported for their anti-...
AAAS announces winners of 2007 AAAS Science Journalism Awards
...ot only Julians early struggles to open doors traditionally closed to blacks but also his keen sense for how to do science. His work with steroids and alkaloids
helped bring about a host of affordable and effective treatments for diseases like rheumatoid arthritis and glaucoma. The judges praised the program f...
Opium and marijuana research go underground
...d for the production of high-value bioproducts. Opium poppy accumulates the alkaloids
morphine, codeine and thebaine, and cannabis produces psychoactive cannabin...etabolic engineering of opium poppy to accumulate high-value pharmaceutical alkaloids
and to block cannabinoid production in cannabis. The latter will allow for ...
Alkaloids in Biological Definition
...structure or physical properties into one or more of the following groups: alkaloids
, terpenoids , polyketides , aliphatic , aromatic , and heteroaromatic ...s .
List of most important secondary metabolites of plants :
Hyoscyamine , present in Datura stramonium
Atropine , prese...
Alkaloids in Biological Dictionary
...... Unfortunately, this endophyte produces toxic alkaloids
that greatly decrease ... inside the plant ( ...... Unfortunately, this endophyte produces toxic alkaloids
that greatly decrease ... these "novel" endophyte...ndophytic fungus, which produces several types of alkaloids
that are toxic to ... Tall fescue (Festuca arun...