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Aliskiren in Medical News

New Survey Finds Majority of Adults Don't Understand a Key Source of High Blood Pressure

...m References Harris Interactive QuickQuery Survey. Custom Tables. Muller DN, Luft FC. Direct renin inhibition with aliskiren in hypertension and target organ damage. Clin J Am Soc Nephrol . 2006:221-228. Harris Interactive QuickQuery Survey. Main Database Tables. ...

New target for maintaining healthy blood pressure discovered

...pressure target components of the RAAS pathway. For instance, ACE inhibitors such as captopril (Capoten) target the formation of angiotensin II, while aliskiren (Tekturna) targets renin. The team assessed the impact of the PG F2-alpha receptor mutations on both blood pressure and RAAS activity. They found t...

Two-Drug Combo Reduces Diabetic Kidney Damage

... the researchers warn that testing the combination of losartan (Cozaar) and aliskiren (Tekturna) to block the activity of a molecule that damages renal arteries ...tages. Losartan is often prescribed for high blood pressure in diabetes. aliskiren blocks the pathways that allow the vessel-damaging molecule -- angiotensin ...

Blood pressure drug may have added benefit

...covered a possible added benefit of a novel new drug that lowers blood pressure. Dr. Lisa Cassis and Dr. Alan Daugherty found in animal studies that aliskiren not only lowered blood pressure but also significantly reduced artery-clogging lesions that are the leading cause of heart attack and stroke, the top ...

Aliskiren: A New Treatment For Hypertension

... aliskiren can possibly be the latest method of treating pati...rtension. Data emerging from early studies of aliskiren indicate that the new drug is effective as a singl...is now good evidence that as a stand-alone therapy aliskiren reduces blood pressure significantly compared with...
Aliskiren in Medical Technology

FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent

... Tekturna HCT is available in four strengths as tablets containing aliskiren and hydrochlorothiazide: 150 mg/12.5 mg tablets, 150 mg/25 mg tablets, 300 ...artis.com * Tekturna(R) is the US trade name for aliskiren. aliskiren is known as Rasilez(R) outside the US. ...

New Data Highlights Potential of SPP100 (Tekturna) as Gold Standard Therapy in Treatment of Hypertension

...ma renin activity persisted 4 weeks after stopping aliskiren treatment in parallel with sustained blood pressure reductions, suggesting that aliskiren has continued inhibitory effects on the renin syst...sential hypertension. The direct renin inhibitor aliskiren in combination with valsartan provides additional ...

Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension

...intervals Office blood pressure (systolic and diastolic) is measured when the patient is in the physician's office at pre-determined intervals [4] aliskiren Reduces Blood Pressure and Suppresses Plasma Renin Activity in Combination With a Thiazide Diuretic, an Angiotensin-Converting Enzyme Inhibitor, or an...
Aliskiren in Biological Technology

Video and Photo: Tekturna HCT(R), a Single-tablet Combination of Tekturna(R)* and a Diuretic, Receives US Approval for Treatment of High Blood Pressure

...n over 140 countries around the world. For more information, please visit http://www.novartis.com . Tekturna(R) is the US trade name for aliskiren. aliskiren is known as Rasilez(R) outside the US. ...
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