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Alagille in Medical News

Second Alagille Syndrome Gene discovered: More information on kidney disease

Genetics researchers at the Children's Hospital of Philadelphia have discovered a second gene that causes Alagille syndrome, a developmental disease with a genetic basis that affects many organs.// This finding may have broader implications in the understanding of kidney disorders. The Children...

Grant Supports Study of Abnormal Ring-Shaped Chromosomes

... Spinner, the director of the Clinical Cytogenetics Laboratory at Children's Hospital, previously discovered genes responsible for the genetic disease alagille syndrome, which affects multiple organs. Children's Hospital has one of the world's leading programs for the diagnosis and treatment of genetic diseas...
Alagille in Medical Dictionary

Syndrome

...ence of symptoms, ... Article about Turner Syndrome . In it female sexual characteristics are present but generally underdeveloped. Describes alagille syndrome , a rare, inherited disorder that affects the liver. ... The syndrome occurs in about one in every 70,000 births 1 and is equally common ....
Alagille in Biological News

Grant supports study of abnormal ring-shaped chromosomes

.... Spinner, the director of the Clinical Cytogenetics Laboratory at Childrens Hospital, previously discovered genes responsible for the genetic disease alagille syndrome, which affects multiple organs. Childrens Hospital has one of the worlds leading programs for the diagnosis and treatment of genetic diseases...

Gene discovery may shed light on kidney disease

...a have identified a second gene that gives rise to alagille syndrome, a genetic developmental disease that aff...ney abnormalities in patients and families. "While alagille syndrome is relatively rare, organ diseases are no...dentified mutations in the JAG1 gene as a cause of alagille syndrome in 1997. Like the NOTCH2 gene analyzed in...
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