Proteins anchor memories in our brain
...ork involving a protein in the cell nucleus called aire (for autoimmune regulator), which regulates the ex... in the thymus. Humans and mice lacking the normal aire gene suffer from multiple autoimmune diseases incl...olleagues there demonstrated that knocking out the aire gene in the mouse thymus led to failures of expres...Autoimmune disease triggered if T cells miss a single protein early on
...ork involving a protein in the cell nucleus called aire (for autoimmune regulator), which regulates the ex... in the thymus. Humans and mice lacking the normal aire gene suffer from multiple autoimmune diseases incl...olleagues there demonstrated that knocking out the aire gene in the mouse thymus led to failures of expres...New pathways for autoimmune treatment identified
...er cells in autoimmune disease. Mutation in the aire gene causes APS1, a disease causing two out of thr...e the status of these cells in a mouse missing the aire gene. That aire knockout is a good model for humans with APS1. ...