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Aire in Medical Definition

Autoimmune regulator

...une Regulator Identifiers Symbol aire Alt. Symbols AIRE1, APECED, APS1, APSI, PG...2.3 The Autoimmune Regulator, abbreviated aire , is a human gene which is expressed in the thymu...asis-Ectodermal Dystrophy (APECED). Disruption of aire results in the development of a range of autoimmu...

Central tolerance

...es. In the case of T cell central tolerance, additional sources of antigen are made available in the thymus by the action of the transcription factor aire . After exposure to self antigens, T cells and B cells become immunologically tolerant (non-reactive) in a number of ways : Negative selection ...

Thymocyte

...hymocytes reactive to peripheral organs, the gene aire drives the expression of multiple peripheral anti...Immunological Self-Shadow Within the Thymus by the aire Protein. Science 298 (5597), 1395-1401 ^ Liston, A. et al. (2003) aire regulates negative selection of organ-specific T c...
Aire in Biological News

Proteins anchor memories in our brain

...ork involving a protein in the cell nucleus called aire (for autoimmune regulator), which regulates the ex... in the thymus. Humans and mice lacking the normal aire gene suffer from multiple autoimmune diseases incl...olleagues there demonstrated that knocking out the aire gene in the mouse thymus led to failures of expres...

Autoimmune disease triggered if T cells miss a single protein early on

...ork involving a protein in the cell nucleus called aire (for autoimmune regulator), which regulates the ex... in the thymus. Humans and mice lacking the normal aire gene suffer from multiple autoimmune diseases incl...olleagues there demonstrated that knocking out the aire gene in the mouse thymus led to failures of expres...

New pathways for autoimmune treatment identified

...er cells in autoimmune disease. Mutation in the aire gene causes APS1, a disease causing two out of thr...e the status of these cells in a mouse missing the aire gene. That aire knockout is a good model for humans with APS1. ...
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(Date:9/22/2014)... By Amy Norton ... -- Tiny preemies may fare better when newborn intensive care ... time with their infants, a new study finds. Researchers ... were more alert and were less distressed when their NICU ... families. The findings, published online Sept. 22 in the ...
(Date:9/22/2014)... transplant seems futuristic, if not impossible. But with ... Defense, researchers at University of California, San Diego ... of an entire, functional eye a reality. , ... grail for vision restoration," said Jeffrey Goldberg, MD, ... colleagues at University of Pittsburg Medical Center and ...
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(Date:9/22/2014)... 22, 2014. Kessler researchers have published a pilot ... wellness program in people with multiple sclerosis (MS). ... health, perceived stress, and pain. "Development and ... living with MS: Description and outcomes" was epublished ... International Journal of MS Care (doi: ...
(Date:9/22/2014)... News) -- Scans of young children,s brains might ... finding could potentially allow doctors to identify those ... preliminary research suggests. "Early identification and interventions ... well as most neurodevelopmental disorders," the study,s senior ... child and adolescent psychiatry at University of California, ...
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(Date:9/22/2014)... areas of sea ice melt in the summer and when ... thinner and more reduced. As the Arctic summers are getting ... reduced sea ice in the Arctic will remove less CO2 ... are representative, then sea ice plays a greater role than ... global CO2 budgets", says Dorte Haubjerg Sgaard, PhD Fellow, Nordic ...
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(Date:9/21/2014)... and barnacles secrete very sticky proteins that help them ... by these natural adhesives, a team of MIT engineers ... repair ships or help heal wounds and surgical incisions. ... researchers engineered bacteria to produce a hybrid material that ... bacterial protein found in biofilms slimy layers formed ...
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