To control germs, scientists deploy tiny agents provocateurs
Aiming to thwart persistent bacterial infections and better control group behaviors of certain microorganisms, scientists are creating artificial chemicals that infiltrate and sabotage bacterial "mobs." Reporting the work here today (March 13) at the 229th national meeting of the American Chemical Society, University of Wisconsin-Madison chemistry professor Helen Blackwell described the o...'Gadonanotubes' greatly outperform existing MRI contrast agents
Researchers at Rice University, the Baylor College of Medicine, the University of Houston and the Ecole Polytechnique Fédérale de Lausanne in Switzerland have created a new class of magnetic resonance imaging (MRI) contrast agents that are at least 40 times more effective than the best in clinical use. The new agents -- dubbed gadonanotubes -- use the same highly toxic metal, gadolinium, t...Tiny avalanche photodiodes target bioterrorism agents
After the anthrax attacks in the United States in 2001 the threat of a larger and more deadly bioterrorism attack -- perhaps from smallpox, plague or tularemia -- became very real. But the ability to detect such biological agents and rapidly contain an attack is still being developed. In a significant finding, researchers at Northwestern University's Center for Quantum Devices have demonst...Software 'agents' could help unmask reality of disease clusters
Concerns over the privacy of patients could be hampering efforts to spot disease clusters and monitor the health effects of environmental pollution, according to researchers in the latest edition of the Data made available to research groups investigating everything from cancer clusters to the risk of living near to hazardous waste sites is often r...Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis. Now, research by scientists at the Unive...GenomONE-Neo EX HVJ-E 4 vial(s) Transfection Reagents from Cosmo Bio Co., Ltd.
Description:HVJ (hemagglutinating virus of Japan, also named Sendai virus) Envelope VECTOR KIT is a tool for transfection of molecules by means of membrane fusion. Most efficient transfection are for siRNA (RNAi), Protein, Oligo, cDNA, Antibodies, Vector, and Biomolecule in vitro and in vivo. GenomONE-Neo EX has a high fusing capability in short period of time that benetif sensitive primary cells or tissues...Human and Mouse RAR Neutralizing Peptide from ABR-Affinity BioReagents
Description:PEP-005 is a synthetic peptide whose sequence is from the C-terminal end of the mouse retinoic acid receptor beta (RAR*). The 21 amino acid sequence extends from amino acids 429 to 448 of RAR*. The sequence of PEP-005 is (amino to carboxy terminus): C - P - S - V - S - P - S - S - V - E - N - S - G - V - S - Q - S - P - L - L - Q (The N-terminal cysteine has been added to facilitate conjugatio...Rat rab 3D Neutralizing Peptide from ABR-Affinity BioReagents
Description:PEP-126 is an 18 amino acid synthetic peptide whose sequence corresponds to residues 1-18 from rat rab 3D. The sequence of this peptide is (amino to carboxy terminus): M(1) - A - S - A - S - E - P - P - A - S - P - R - D - A - A - D - Q - N(18). This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat rab 3D, cata...Rat SAP97 Neutralizing Peptide from ABR-Affinity BioReagents
Description:PEP-055 is a 20 amino acid synthetic peptide whose sequence corresponds to residues 115-133 of rat SAP97. The sequence of this peptide is (amino to carboxy terminus): V115 - L - P - S - E - R - I - S - P - Q - V - P - N - E - V - L - G - P - E133 (C) (The C-terminal cysteine has been added to facilitate conjugation and is not a part of the native rat SAP97 sequence.). This peptide may be u...Rat SCAMP 5 Neutralizing Peptide from ABR-Affinity BioReagents
Description:PEP-152 is a 17 amino acid synthetic peptide whose sequence is from rat SCAMP 5. The sequence of this peptide is (amino to carboxy terminus): C - N(217) - Q - P - Q - T - Q - Y - S - A - T - P - N - Y - T - Y - S - N(233). This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and the rat SCAMP 5, catalog # PA1-737. U...A Comparison Study of Lipid Tranfection Reagents in A549, NIH 3T3 and COS-7 Cell Lines
Genetic Applications LLC transfection reagent canbe used for simple and reproducible delivery of foreign DNA into mammaliancells. In this study, we used varying amounts of LipoTAXI transf...Medical College lands $8.1M grant to detect bird flu, bioterror agents
The grant, which was awarded by the <a href="http...Third Wave releases reagents for Hepatitis C testing
MADISON - The Hepatitis C virus is the leading cause of liver disease in the United States and affects 4 million Americans, leading to about 10,000 deaths annually, according to a co...Reagents for Up and Down-Regulation of miRNA Activity in Mammalian Cells
More than 200 miRNAs have been cloned and sequenced from human and mouse samples. Each miRNA apparently regulates multiple genes, and miRNAs are thought to regulate as many as 10% of human genes [1]. Several reports predict mR...New target for antidiabetic agents identified
U.S. researchers have identified a protein that could serve as a new target for drugs designed to treat type II diabetes. The protein, known as TRB3, is actually a homolog of a protein found in the fruit fly Drosophila tribbles, senior author Dr. Marc Montminy, from the Salk Institute for Biological Studies in La Jolla, California, and colleagues note. The focus on TRB3 was the result of...Gold Nanoparticles: Agents For Noninvasive Cancer Therapy
Gold nanoparticles are potential and very practical agents in therapeutic applications. Researchers from the University of California, San Francisco and Georgia Institute of Technology, writing Cancer Letters // (Available online 28 September) demonstrate the efficiency of gold nanospheres as photothermal agent by selectively delivering gold nanoparticles to oral carcinoma cells that over...New Multi-Modal Contrast Agents, A Boon For Medical Imaging
Medical imaging techniques like ultrasound and computed tomography (CT), magnetic resonance imaging and molecular imaging can all be made better by the newly developed multi-modal contrast agent – Researchers // at the University of Illinois at Urbana-Champaign says. Use of these new agents may, in turn, significantly improve the diagnosis and treatment of cancer, according to Kenneth W...Newer Contrast Agents Safe for Children
Allergic-like reactions to newer iodine-containing contrast agents (nonionic contrast media), are rare in children according to a recent study conducted by researchers from the University of Michigan Medical Center and C.S. Mott Childrens Hospital both in Ann Arbor. 'A major, if not the main, risk associated with iodine-containing contrast agents is allergic types of reactions. Suc...Less Allergic Reactions to Iodine-containing Contrast Agents in Children
Children show less allergic reactions to iodine-containing contrast agents ,according to a recent study conducted by researchers from the University of Michigan Medical Center and C.S. Mott Childrens Hospital both in Ann Arbor. A major, if not the main, risk associated with iodine-containing contrast agents is allergic types of reactions. Such reactions can be mild; for example, hives...Creatinine Test Kit (enzymatic, liquid reagents)
Description:Creatinine Test Kit (enzymatic, liquid reagents), Wavelength: 550 nm. Linear range: up to 150 mg/dL....Rheumatoid Factor - Liquid Immunoassay Reagents
Description:Rheumatoid Factor R1: 4 X 20 ml buffer R2: 2 X 8 ml antibody Test / Kit: 320 (H717)...Lyophilized ITA Control for K - ASSAY® Reagents
Description:The K-ASSAY ITA Lyophilized Multi-Control Set is intended to be used as a consistent test sample of known concentration for monitoring the performance of K-ASSAY immunoturbidimetric assays for the listed constituents....Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse
In keeping with the recent proliferation of rapid, easy-to-use diagnostic tests, many assays and collection products have entered the marketplace to help clinicians assess dosage appropriateness of therapeutic drugs and to screen for the presence of drugs of abuse. Some of these products require laboratory support while many simple test kits are suitable for point of care use by medical profe...Kosan Presents Preclinical Data on Nuclear Export Inhibitors, Novel Anticancer Agents, at AACR
HAYWARD, Calif., April 18, 2007 /PRNewswire-FirstCall/ -- KosanBiosciences Incorporated today presented preclinical data on itsproprietary nuclear export inhibitors (NEI) showing induction ofpotent, fast-acting and long-lasting anticancer activity with ahigh degree of tolerability in multiple human tumor xenograftcancer models. Kosan's NEIs are potent, specific inhibitors of CRM1,...Afid Therapeutics Obtains Positive Evaluation of its Triple Mode Viral Sequestration Agents
LANSING, Mich., March 27, 2007 /PRNewswire/ -- AfidTherapeutics, Inc. announced that it received positive results onthe ability of its new triple mode viral sequestration agents toblock viral infections of mammalian cells. The audited results wereobtained from a specialized, independent third party testingorganization. The new viral sequestrating agents are designed tobind and inactivate...