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adjuvant in Medical News

Avastin Unsuccessful as Adjuvant Therapy in Setting of Stage II and III Colon Cancer but May Be Effective if Given for Longer Duration

Cancer researchers from the National Surgical Adjuvant Breast and Bowel Project (NSABP) and Allegheny General Hospital (AGH) in Pittsburgh reported today at the annual meeting of the American Society of Clinical Oncology (ASCO) in Orlando that use of the drug bevacizumab (Avastin) in combination ...

Use of Avastin and Erbitux in the Adjuvant Setting and Launches of Emerging Agents Will Drive the Colorectal Cancer Drug Market to $7.8 Billion in 2017

Unmet Need for Efficacious Therapies for Treating Patients With Mutated KRAS Genes Presents Significant Opportunity for Drug Developers, According to a New Report from Decision Resources WALTHAM, Mass., March 11 /PRNewswire/ -- Decision Resources, one of the world's leading research and advis...

An adjuvant chemotherapeutic agent in gastric cancer therapy

Peritoneal carcinomatosis can be thought of as a series of events that together form a peritoneal metastatic cascade. The peritoneal stromal tissue appears to be a friendly host for tumour proliferation, providing a rich source of growth factors and chemokines known to be involved in tumour metast...

Nanoemulsion-Based Intranasal Influenza Vaccine Adjuvant Triggers Robust Immunity Using Significantly Less Antigen

Data presented at the 2008 ICAAC/IDSA meeting in Washington, DC WASHINGTON, Oct. 27 /PRNewswire/ -- A single administration of a novel, nasally delivered influenza vaccine elicited immune responses in ferrets that were more than 20 times higher than those generated by two injections of the...

Genomic Health Announces Oncotype DX(R) Provides Additional Prognostic Benefit in Patients Assessed With Adjuvant Online

- Comparison Study Confirms Oncotype DX Recurrence Score Result Has Strongest Association with Breast Cancer Recurrence - SAN ANTONIO, Dec. 15 /PRNewswire-FirstCall/ -- Genomic Health, Inc. (Nasdaq: GHDX ) today announced positive results from a study showing that the Oncotype DX Re...

Infectious Disease Research Institute Receives Grant from the Bill & Melinda Gates Foundation for Adjuvant Access and Development

SEATTLE, Dec. 4 /PRNewswire/ -- The Infectious Disease Research Institute (IDRI), a Seattle-based non-profit scientific research institute, announced today that it has received a $29,947,850 five year grant from the Bill & Melinda Gates Foundation. The grant will be used to provide adjuvants (...

New Adjuvant Breast Cancer Treatments Found Cost-effective

Two new studies have found that new adjuvant treatments for breast cancer are cost-effective at improving survival. Published in the August 1, 2007 issue of Cancer, a journal of the American Cancer Society, the two studies looked at the cost-effectiveness of different drugs for the managem...

Bird-flu Vaccine Adjuvant Contract Goes to Novartis

Swiss-based global pharmaceutical giant Novartis bagged the contract to make a chemical that would boost the effectiveness of bird-flu vaccines. The $54.8 million contract// was finalised on Wednesday. The company already has more than $300 million in federal contracts to fight a possible bir...

Surgery and Adjuvant Therapy Can Work for Pancreatic Cancer

In the largest single-institution retrospective study to date, researchers at Mayo Clinic Cancer Center have shown that giving patients// both radiation and chemotherapy after completely removing invasive pancreatic cancer may improve overall survival rates. The American Cancer Society repor...

Sagent Pharmaceuticals Announces Launch of First Two Oncolytic Products: Fludarabine Phosphate for Injection, USP and Epirubicin Hydrochloride Injection

...ride Injection Epirubicin hydrochloride injection (generic equivalent to Ellence(R), distributed by Pfizer Oncology) is indicated as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer. The package insert, which is...
adjuvant in Medical Technology

Glivec(R) is the First Adjuvant Treatment Approved in the UK to Delay Return of Gastrointestinal Cancer After Surgery

FRIMLEY, England, May 8 /PRNewswire/ -- - Glivec(R) (imatinib) Now Approved in the UK for Post-Surgery Treatment of Patients With KIT (CD117)-Positive Gastrointestinal Stromal Tumours (GIST), who are at Significant Risk of the Cancer Returning After Surgery(1) - Use of Glivec(R) ...

Surveyed Oncologists Say That the Most Promising Targeted Therapy in Adjuvant Clinical Trials is Avastin for the Treatment of Early-Stage Colorectal Cancer

Despite Widespread Use, Formulary Coverage of Targeted Cancer Therapies is Inconsistent, According to a New Report from Decision Resources WALTHAM, Mass., Oct. 14 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issu...

Vical Expands Applications of Vaxfectin(R) Adjuvant for Infectious Disease and Cancer Vaccines; 80% to 100% of High-Dose Responders in H5N1 Clinical Trials Still Responding at 6 Months

LYON, France, Oct. 8 /PRNewswire/ -- Vical Incorporated (Nasdaq: VICL ) today is presenting expanded clinical data and new nonclinical data demonstrating that the company's Vaxfectin(R) adjuvant may be broadly applicable in DNA- and protein-based infectious disease vaccines and peptide-based ...

Bayer and Onyx Begin Enrollment in STORM Trial Studying Nexavar as Adjuvant Therapy for Patients With Liver Cancer

WAYNE, N.J. and EMERYVILLE, Calif., Aug. 21 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX ) today announced the companies have begun enrolling patients in the STORM Sorafenib as Adjuvant Treatment in the Prevention of Recurrence ...

Karolinska Institutet to Test Vical's Vaxfectin(R) Adjuvant With Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

SAN DIEGO, Aug. 19 /PRNewswire-FirstCall/ -- Vical Incorporated (Nasdaq: VICL ) today announced a research collaboration with the Karolinska Institutet (KI), a leading European medical university, and the Swedish Institute for Infectious Disease Control (SMI), a governmental expert agency, to...

Karolinska Institute to Test Vical's Vaxfectin(R) Adjuvant with Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control

SAN DIEGO, Aug. 19 /PRNewswire-FirstCall/ -- Vical Incorporated (Nasdaq: VICL ) today announced a research collaboration with the Karolinska Institute, a leading European medical university, and the Swedish Institute for Infectious Disease Control (SMI), a governmental expert agency, to evalu...

Study Supports Possible Use of Leukine(R) as a Potential Adjuvant Therapy for High-Risk Melanoma Patients

- Phase II Data Indicate Overall and Disease-Free Survival - WAYNE, N.J., June 5 /PRNewswire/ -- Results from an adjuvant trial in high-risk melanoma patients demonstrated that a majority of patients treated with Leukine(R) (sargramostim) achieved disease-free and/or overall survival. Th...

Iomai Receives HHS Approval to Begin Phase 2 Trial of H5N1 Influenza Adjuvant Patch

- Dose-Ranging Trial to Further Assess Feasibility of Dose-sparing and Single-Dose Vaccination Against H5N1 Flu - GAITHERSBURG, Md., April 15 /PRNewswire-FirstCall/ -- Iomai Corporation (Nasdaq: IOMI ) today announced that it has received approval from the Department of Health ...

Positive Xeloda(R) Five-Year Overall Survival Study Data in the Adjuvant Treatment of Colon Cancer Presented at Leading European Cancer Meeting

BARCELONA, Spain, Sept. 25 /PRNewswire/ -- Five-year follow-up overall survival data from the X-ACT (Xeloda in Adjuvant Colon Cancer Trial) study show that oral chemotherapy Xeloda(R) (capecitabine) is as effective as the current standard treatment - intravenous bolus 5-FU/LV (5-fluorouracil/ ...

CEL-SCI Presents Data for CEL-1000 as a Vaccine Adjuvant with Recombinant Hepatitis B Virus Protein

VIENNA, Va., Sept. 19 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (Amex: CVM ) announces that its CEL-1000 immunomodulator was shown to be able to jump start the immune response against the recombinant hepatitis B virus protein more quickly than did other vaccine adjuvants. This effect in t...
adjuvant in Medical Products

Pocket Guide to Colorectal Cancer Drugs and Treatment

Features:...cidence, epidemiology, and trends; staging and primary surgical management; adjuvant therapy; and treatment of advanced disease Specific information about each of the chemotherapeutic agents used in systemic treatment as adjuvant therapy of treatment of advanced disease is presented for both the nurse an...
Company:Skyscape, Inc.
adjuvant in Medical Dictionary

Tympanostomy

...stomy tubes in the treatment of chronic otitis media with effusion Original Article from The New England Journal of Medicine -- The Role of adjuvant Adenoidectomy and Tonsillectomy in the Outcome of the Insertion of Tympanostomy Tubes Insertion of tympanostomy tubes is often recommended to ...

Radiation therapy

...rapy is the medical use of ionizing radiation as part of cancer treatment to control malignant cells . Radiotherapy may be used for curative or adjuvant cancer treatment. It is used as palliative treatment or as... Information about what to expect during radiation therapy , including the g...

Paranasal sinuses

...enoid, ... the nasal cavity and paranasal sinuses : a series of 256 patients in Mexico ... Paranasal Sinus Cancer Key Terms: Adenopathy , adjuvant therapy , Adenocarcinoma , Angiogenesis inhibitor , Antimetabolite , Antineoplaston , paranasal sinus ( ¦parə¦nāzəl ′sīnəs ) ( anatomy ) Any...

Growth hormone

...educed abdominal ... Prolonged treatment with growth hormone was able to reduce abdominal adipose ... Low-Dose Growth Hormone (GH) as an adjuvant to Life Style Modifications in the ... When growth hormone is low, the body tends to accumulate body fat, and lose lean ... GENOTROPIN ® Human...

Colon

... cancer screening guidelines for average-risk and high-risk people. ... Test May Warn of Colon Cancer. Colonoscopy Advances Promise Faster ... adjuvant Chemotherapy for Stage III Colon Cancer: Implications of Ethnicity, Age ... The prognosis of T3NO colon cancer is dependent upon the number of...

Adrenocortical carcinoma

...carcinoma information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. adjuvant Mitotane Treatment for Adrenocortical Carcinoma ... Treatment of advanced adrenocortical carcinoma with erlotinib plus gemcitabine. ... Ho...
adjuvant in Biological News

H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses

When combined with an immune-boosting substance called an adjuvant, low doses of an experimental vaccine against a strain of avian influenza (H9N2) provoked a strong antibody response in human volunteers, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAI...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

...ed to kill cancer cells without harming normal cells. Rush is one of only five hospitals in Illinois offering the vaccine. The MAGRIT (MAGE-A3 as adjuvant Non-Small Cell LunG Cancer Immunotherapy) study is a randomized, double-blind and placebo controlled trial that will enroll patients with MAGE A-3-pos...

Researchers identify new anti-tumor gene

...rs and hematological malignancies, such as melanoma, renal cell carcinoma, malignant glioma, lymphomas and leukemias, either as a monotherapy or as an adjuvant to chemotherapy of radiotherapy. "We have uncovered a new way by which interferon can induce anti-tumor activity. The identification of SARI also p...

CTRC-AACR San Antonio Breast Cancer Symposium

...ortant as physical activity in breast cancer prevention Recurrence rates among patients with small HER2-positive tumors Evaluation of letrozole as adjuvant endocrine therapy Phase III trials of new, paradigm-shifting clinical agents like topoisomerase When: December 10-14, 2008 Where: Hen...

International team reveals first prognosticator of survival in aggressive cancer

...stic indicator will help doctors determine which patients have a higher risk of recurrence of the disease and who might benefit from a more aggressive adjuvant therapy. In the study, researchers examined specimens taken from 41 patients with STS. In a subset of 31 cases of nonmetastatic cancers, they found...

Nano vaccine for hepatitis B shows promise for third world

... eliciting systemic protective antibodies in the blood of animals. The nanoemulsion acted as an effective adjuvant, without the need for a traditional adjuvant or inflammatory compound as in the current hepatitis B vaccines. In addition, the nanoemulsion vaccine produced sustained cellular immunity in Th1...

Plasma DNA level is a reliable marker of recurrent esophageal cancer, study finds

... An accurate marker for detecting esophageal cancer that has spread (metastasized) beyond the esophagus may allow for better selection of patients for adjuvant therapy, prediction of response to therapy and early intervention when the disease does recur. Although carcinoembryonic antigen (CEA) and plasma DNA ...

Treatment delays result in poor outcomes for men with breast cancer

... spread to other parts of the body. All the men underwent surgery to remove their cancer. After surgery, 48 received radiotherapy and 100 received adjuvant chemotherapy or hormone therapy. After a median follow-up of 5.2 years, the estimated 10-year disease-free survival rates were 80% for men with the ea...

A protein sequence associated with Huntington’s disease may become life-saving vaccine component

...p by antigen-presenting cells, as is the case with adjuvant droplets, triggering the immune response. Anoth... Lab's paper demonstrates that the new polyQ-based adjuvant efficiently enhances both branches of the immune response to a poor model antigen. Importantly, the adjuvant caused no apparent toxicity in mice. Many ques...

New vaccine may give long-term defense against deadly bird flu and its variant forms

... vaccine uses an adjuvant, molecules added to the vaccine that stimulate the body's immune system, so that lower doses of the vaccine can be used. The adjuvant also allows the vaccine to be stockpiled so more people can be vaccinated, and it helps the vaccine protect against variant forms of the H5N1. The onl...
adjuvant in Biological Technology

FDA Grants Priority Review for Schering-Plough's Peginterferon Alfa-2b for the Adjuvant Treatment of Patients With Stage III Melanoma

KENILWORTH, N.J., Jan. 31 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP ) today announced that the U.S. Food and Drug Administration (FDA) has accepted the Peg-IFN (peginterferon alfa-2b) supplemental Biologics License Application (sBLA) for review and has granted Priority ...

Protherics Licenses its CoVaccine HT Adjuvant to Nobilon for Influenza Vaccine Indications

BOXMEER, The Netherlands and LONDON, September 26 /PRNewswire/ -- Nobilon International B.V., part of Organon, the human health care business unit of Akzo Nobel, and Protherics PLC, the international biopharmaceutical company focused on critical care and cancer, today announced that Nobilon ha...

IDRI and Immune Design Corp. Enter License Agreement on GLA Vaccine Adjuvant

SEATTLE, Nov. 20 /PRNewswire/ -- IDRI (Infectious Disease Research Institute) and Immune Design Corp. announced today that they have entered into an agreement pursuant to which Immune Design Corp. is granted a worldwide exclusive license for the research, development, and commercialization of IDRI...

ImmuneRegen BioSciences Confirms Homspera's Therapeutic Anti-Influenza Effect on Pandemic H1N1 Influenza Virus After Oral Administration

...al treatments for blood disorders and to accelerate wound healing. Findings to date suggest additional opportunities for these compounds as a vaccine adjuvant and potential treatment for influenza or other microbial ailments, as well as for use as a possible countermeasure for homeland security threats inclu...

Sanofi-aventis Announces Second Quarter 2009 Results

...ed second-quarter growth of 10.7% to euro 584 million, driven by its use in adjuvant breast cancer treatment and in prostate cancer. Growth was good across all ... ((R)) , the leading cytotoxic agent in the colorectal cancer market as an adjuvant and as a first-line treatment in the metastatic phase, achieved second-quar...

Genomic Health Reports Favorable Commentary on Value of Multigene Assays From the St. Gallen Expert Consensus Meeting on the Primary Treatment of Early Breast Cancer

...upported the use of a validated multigene-profiling assay as an adjunct to high-quality phenotyping of breast cancer in cases where the indication for adjuvant chemotherapy is uncertain. "These new guidelines provide further evidence that the international clinical community sees the value of advanced mo...

CEL-SCI Developing Immune-Based Treatment Against Swine and Other H1N1 Flu Viruses Using Proprietary L.E.A.P.S. Technology

...s CEL-1000 peptide, which is derived from the L.E.A.P.S. technology, showed adjuvant activity when used with a peptide based malaria vaccine and a DNA based mal... L.E.A.P.S. has the potential to be used either alone as a therapy or as an adjuvant to vaccines under development for the treatment of H1N1 related flu viruses...

Bayer and Onyx Announce Nexavar Data Presentations at 45th American Society of Clinical Oncology Annual Meeting

...a single agent or combination treatment in a wide range of cancers, including breast cancer, colorectal cancer, lung cancer, ovarian cancer, and as an adjuvant therapy for kidney cancer and liver cancer. Important Safety Considerations For Patients Taking Nexavar Based on the currently approved U.S....

YM BIOSCIENCES REPORTS THIRD QUARTER 2009 OPERATIONAL AND FINANCIAL RESULTS

...ring the third quarter of fiscal 2009: - The National Cancer Centre of Singapore (NCCS) selected nimotuzumab for evaluation in the adjuvant setting in a multinational Phase III trial of more than 700 patients with cancers of the head and neck, citing the drug's benign safet...

Lilly Set to Unveil More Than 50 Studies at ASCO 2009

...entation: May 31, 2009, 10:30 a.m. A phase III study comparing concurrent gemcitabine (Gem) plus cisplatin (Cis) and radiation followed by adjuvant Gem plus Cis versus concurrent Cis and radiation in patients with stage IIB to IVA carcinoma of the cervix This study is being presented a...
adjuvant in Biological Products

Incomplete Adjuvant from Santa Cruz Biotechnology, Inc.

Description: Incomplete Adjuvant...
Company:Santa Cruz Biotechnology, Inc.

Complete Adjuvant from Santa Cruz Biotechnology, Inc.

Description: The mycobacteria in Complete Freund's adjuvant attract macrophages and other cells to the injection site which enhances the immuneresponse. For this reason, the Complete Freund's Adjuvant is used for the initial injections; Incomplete Freund's adjuvant is used for the subsequent boosts. Antigen...
Company:Santa Cruz Biotechnology, Inc.

Incomplete Adjuvant from Santa Cruz Biotechnology, Inc.

Description: Lacks the mycobacteria found in Complete Freund's Adjuvant so it minimizes the side-effects. For this reason, Incomplete Freund's Adjuvant is used for the boost injections. Freund's Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions s...
Company:Santa Cruz Biotechnology, Inc.

Imject Freund's Incomplete Adjuvant (FIA) from Pierce Biotechnology, Inc.

Description: Imject Freund's Incomplete Adjuvant (FIA)...
Company:Pierce Biotechnology, Inc.

Freund's Complete Adjuvant from CHEMICON

Description: Request Info...
Company:CHEMICON

Imject Freund's Complete Adjuvant (FCA) from Pierce Biotechnology, Inc.

Description: Imject Freund's Complete Adjuvant (FCA)...
Company:Pierce Biotechnology, Inc.

Polyclonal Antibody Production from Agro-Bio

Description:... Immunize with antigen in Complete Freund's adjuvant (CFA) Day 14 : Immunize with antigen in Incomplete Freund's adjuvant (IFA) Day 28 : Immunize with antigen in Incomplete Freund's adjuvant (IFA) Day 42 : Immunize with antigen in Incomplet...
Company:Agro-Bio

Freund's Complete Adjuvant, Modified, Mycobacterium butyricum from Calbiochem

Description:... Clear amber to slightly cloudy liquid. Yellow, oily, bacterial suspension. Contains 10 vials per set, each containing 10 ml of Freund's complete adjuvant homogenized in the following proportions by weight: 85% Drakeol 5NF, 15% Arlacel A (mannide monooleate emulsifier), and 0.1% Mycobacterium butyricum ...
Company:Calbiochem

Custom Antibody Production Services from Aves Labs, Inc.

Description:...period of 3-5 days), we begin the injection series. This involves a total of four injections into the breast muscle. The first is in Complete Freunds' adjuvant and the remaining injections use a 1:1 dilution of complete and incomplete Freund's Adjuvants. Following the fourth injection, we wait a week, and the...
Company:Aves Labs, Inc.

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adjuvant in Biological Definition

Cancer

...rmining the extent of the disease and whether there has been metastasis to regional lymph nodes . Staging determines the prognosis and the need for adjuvant therapy. Chemotherapy Chemotherapy is the treatment of cancer with drugs ("anticancer drugs") that can destroy cancer cells. It interferes ...

Immune system

... is artificially introduced into a host. With the adjuvant, the response is much more robust. Historically, a commonly used formula Freund's Complete adjuvant , an emulsion of oil and mycobacterium . It was later discovered that toll-like receptors, expressed on innate immune cells, are critical in the acti...
adjuvant in Biological Dictionary

Peripheral protein

...iate with lipid bilayers ... ... disorders of myelin proteins that affect peripheral nerves do not ... animals with myelin and Freund adjuvant or purified peripheral myelin protein P2. ... A summary of Membrane Proteins in 's Cell Membranes. ... Peripheral proteins are less mob...
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(Date:7/9/2014)... Researchers have found that fecal transplantation is effective ... immunocompromised patients. This is the result of a study ... Center for Women,s Gastrointestinal Medicine at The Women,s Medicine ... online in advance of print in the American ... or C. diff , has increased to epidemic ...
(Date:7/9/2014)... are personal and subjective, the human brain turns ... emotions across different senses, situations and even people, ... Adam Anderson. , "We discovered that fine-grained patterns ... area of the brain associated with emotional processing, ... individual,s subjective feeling," says Anderson, associate professor of ...
(Date:7/9/2014)... 8, 2014) Researchers from Montefiore Medical Center ... of Yeshiva University will present new findings at ... 12 July 17 in Copenhagen, Denmark. Data from ... prompt transition from cognitive normality to mild cognitive impairment ... Einstein Aging Study , established in 1980 to examine ...
(Date:7/9/2014)... smell of flatulence and have a reputation for being highly ... sulfide is now being being found to offer potential health ... heart attacks and dementia. A new compound (AP39), designed and ... to future therapies, by targeting delivery of very small amounts ... cells. , Scientists in Exeter have already found that ...
(Date:7/9/2014)... conducted by researchers at Tufts University School of Dental ... and developmental disabilities, the likelihood of having cavities decreased ... The findings, published in the July/August issue of ... designed to address the oral health of individuals in ... records of 107 patients at one of the eight ...
Breaking Medicine News(10 mins):Health News:Women's Medicine Collaborative examines safety of fecal transplant to treat C. difficile 2Health News:Study cracks how the brain processes emotions 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 3Health News:Rotten egg gas holds key to healthcare therapies 2Health News:Adults with special needs see gains, challenges with long term oral care 2Health News:Adults with special needs see gains, challenges with long term oral care 3
(Date:7/9/2014)... one gene for another in a line of living ... reality within this decade. As with any new technology, ... disease-causing genes in humans, for example--as well as questions ... of those concerns to rest: using gene-editing techniques on ... in the cells. The new results were published July ...
(Date:7/9/2014)... As climate change shifts the geographic ranges in which ... it has on their parasites. Does an increased range ... as well? , Not necessarily, says a team of ... Armand Kuris. In a study published in the ... that for some species, the opposite may happen: Hosts ...
(Date:7/9/2014)... Fla. (July 9, 2014) Emerging fungal pathogens ... other parasitic group, causing population declines of amphibians, ... the University of South Florida published in the ... can acquire behavioral or immunological resistance to a ... declines. , "Acquired resistance is important because ...
Breaking Biology News(10 mins):No extra mutations in modified stem cells, study finds 2No extra mutations in modified stem cells, study finds 3Not at home on the range 2Not at home on the range 3Not at home on the range 4USF study: Amphibians can acquire resistance to deadly fungus 2
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