Fat-Cell Protein May Reduce Diabetes Risk
... Higher levels of adiponectin
linked in studies to lower incidence of type 2 dia...can Medical Association .
"Our finding was that adiponectin
is associated with a low risk of type 2 diabetes, ...n Dam said that he and his colleagues believe that adiponectin
isn't just a marker for a decreased risk of type 2...
Hormone Could Improve Diabetes Treatment
...nt of type 2 diabetes, U.S. researchers report.
is a metabolic hormone that regulates a number of ...Previous research has shown an association between adiponectin
and insulin sensitivity.
This new study found t...om several clinical trials revealed that levels of adiponectin
in the blood are able to predict activation of rec...
Test for hormones in blood not reflective of hormones in breast tissue; breast cancer risk
...nd leptin. High levels of IGF-1 has been linked to breast cancer development, while low levels of IGFBP-3 is linked to increased risk. High levels of adiponectin
and leptin are both related to obesity, which is, in itself, a risk factor for breast cancer.
"By understanding these hormones in the normal breast...
'Fasting Signal' Offers Clues to Insulin Resistance in the Obese
...tissues as well. They found that CREB activity in fat cells in obese mice encourages insulin resistance by lowering the production of a hormone called adiponectin
and the insulin-sensitive glucose transporter 4 (GLUT4).
Obese mice genetically altered to lack CREB in fat cells became more sensitive to insulin ...
Mice Study Shows How 'Fat Gene' Works
...ptin is produced by fat tissue.
Levels of adiponectin, another hormone involved in metabolic processes, were increased in the mice. Lower levels of adiponectin
are associated with obesity.
The scientists were able to rule out changes to the hypothalamus, a part of the brain involved in "energy homeostasis"...
Another reason to avoid high-fat diet -- it can disrupt our biological clock
...iochemistry, tested whether the clock controls the adiponectin
signaling pathway in the liver and, if so, how fasting and a high-fat diet affect this control. adiponectin
is secreted from differentiated adipocytes (fat ti... by a fasting day, then measured components of the adiponectin
metabolic pathway at various levels of activity. I...
Fat Cell Protein Boosts Heart Attack Risk in Elderly
... Higher adiponectin
levels may indicate underlying disease, study find...are losing weight, a new report says.
Levels of adiponectin
increase in the bloodstream when people lose weigh... appears odd, because past studies have shown high adiponectin
concentration is associated with lower risks of di...
Protein made by fat cells may increase risk of heart attack in older adults
... As people lose weight, the concentration level of adiponectin
in the bloodstream increases. In previous studies, high adiponectin
concentration has been associated with lower occur...h blood sugar and cholesterol parameters, elevated adiponectin
levels may lead to heightened risk of heart attack...
CARDIA Studies Open Window on Heart, Lung Diseases
...association between low levels of a protein called adiponectin
in fat cells to increased asthma risk in young women. Even though adiponectin
is produced by fat cells, obesity may trigger an i...omen into three groups, according to the amount of adiponectin
produced by their fat cells.
Women with the low...
Studies provide insights into lung disease and lung function in young adults
...g adults. One links low levels of a protein called adiponectin
in fat cells to an increase in asthma risk in youn...A study being presented at 8:15 a.m.
is produced in fat cells, obesity may trigger an i...roduction is diminished in obese people. Levels of adiponectin
increase with weight loss. To determine the effect...
Adiponectin in Medical Technology
Adiponectin in Medical Dictionary
...iated uptake of glucose and vitamin C uses white blood cells. ... Circulating insulin , C peptide, IGF binding protein (IGFBP)-1, and adiponectin
... glucose (A), insulin dose (B), serum insulin levels ( C ), serum C-peptide levels ... ...
Adiponectin in Biological News
Adiponectin is a metabolic link between obesity and bone mineral density
...f Experimental Biology and Medicine . Circulating adiponectin
levels are significantly lower in obese humans and...ment of Nutritional Sciences, investigated whether adiponectin
modulates bone development using transgenic mice t...ssess bone development. Female mice overexpressing adiponectin
had weaker vertebra at 8 weeks of age than control...
Resveratrol prevents fat accumulation in livers of 'alcoholic' mice
...ator alpha (PGC-1α)
Elevation of circulating adiponectin, a hormone produced by fat cells, which helps control obesity
Enhanced expression of adiponectin
receptors in the liver, which increases the effectiveness of the circulating adiponectin.
The findings suggest that resveratrol prevents alcohol...
Bisphenol A linked to metabolic syndrome in human tissue
...taken to the laboratory and incubated with different concentrations of BPA or estrogen for six hours to observe how the varied amounts of BPA affected adiponectin
levels. The effects of BPA were then compared to those of estradiol, a natural form of human estrogen.
They found that exposing human tissues to BP...
T-cadherin affects blood vessel growth in breast cancer, hormone from fat cells may play a role
...atty tissue that is released in inversely proportional amounts to body fat. adiponectin
has a protective effect against metabolic diseases including diabetes, hype...plex, this study shows that in the mouse, T-cadherin sequesters much of the adiponectin
and thus provides a conceptual link between obesity and breast cancer notes...
Story ideas from the Journal of Biological Chemistry
... that helps lower glucose production and stimulates cells to use fat for energy instead. The researchers found that Snell mice had three times as much adiponectin
in their blood as control mice; Snell mice also had fewer triglycerides in their cells, indicative of higher fat metabolism.
The benefit of burning...
Research shows skeleton to be endocrine organ
... a high fat diet. Analysis of mice lacking the osteocalcin protein showed that they had type 2 diabetes, increased fat mass, a decrease in insulin and adiponectin
expression, and decreased beta-cell proliferation.
This research was supported by the National Institutes of Health, the American Diabetes Associa...
Adiponectin in Biological Technology
ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA
SALEM, N.H., Aug. 7 /PRNewswire/ -- ALPCO Diagnostics has introduced a Mo u se HMW Adipone c tin EL I SA kit that facilitates the testing process for this biomarker. This ELISA is unique; it is a departure from other methods for determining mouse HMW adiponectin
and was first introd...
JCI table of contents: April 22, 2008
...s, prevention, and treatment of kidney disease.
is a soluble factor secreted by fat tissue, but the amount of adiponectin
secreted decreases as an individual becomes more o...t high risk of developing kidney disease levels of adiponectin
in the bloodstream correlated inversely with album...
Adiponectin in Biological Definition
... thyroxine (T4)
Peptide hormones :
antimullerian hormone (AMH, also mullerian inhibiting factor or hormone)
adrenocorticotropic hormone (ACTH, also corticotropin)
angiotensinogen and angiotensin
antidiuretic hormone (ADH, also va...