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Adenylate in Medical News

Hormone shows promise in reversing Alzheimer’s disease and stroke

...d to be to work." The therapy known as PACAP27 -- is a hormone produced by the body that is a general neuro-protectant. PACAP stands for pituitary adenylate cyclase-activating polypeptide. "It is a general protector of the brain against many types of insult and injury," Banks says. He compares a specif...

NuView Radiopharmaceuticals, Inc. Secures Exclusive Rights From Thomas Jefferson University for a Tumor-Specific Imaging Agent for the Diagnosis of Breast and Prostate Cancers

...human tumors over-express vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) receptors known as VPAC1, VPAC2 and PAC1...ing the binding of the small molecule peptide PACAP to vasoactive pituitary adenylate cyclase (VPAC) receptors expressed in high density on tumors. "The need f...

Caught in the act: The dynamic dance of enzymes

...f the biological world scientists had once thought, essentially passive until catalysis occurs. Rather, Kern and her team demonstrated that the enzyme adenylate kinase, and presumably many more, engages in a dynamic dance even before its catalytic datethe substrate to which it bindsshows up. If one of the ...

News Tips from the Journal of Neuroscience

...alcium currents and downregulation of potassium currents. Signaling through cAMP pathways downstream of calcium, including Ca 2+ /calmodulin-dependent adenylate cyclase, appear to link the channel activity to more robust growth. 3. Cocaine, Serotonin, and Conditioned Place Preference Thomas S. H...
Adenylate in Medical Technology

Controlling the Spread of Healthcare Associated Methicillin Resistant Staphylococcus aureus Requires Active Surveillance

...llin-containing broth. Staphylococcus aureus-specific magnetic beads are used to capture intact MRSA, and after a wash step, the MRSA are detected by adenylate kinase bioluminescence. The assay can be completed in less than 5 hours. To date sensitivity and specificity from clinical studies have not been rep...
Adenylate in Medical Products

BacLite™

Description:... Acolytes core technology relates to the ultrasensitive measurement of adenylate Kinase (AK), an enzyme found in all living cells. ATP produced by the AK reaction is measured using bioluminescence. By coupling AK Technology to m...
Company:Acolyte Biomedica Ltd
Adenylate in Biological Technology

Utilization of Donkey Anti-Rabbit PS SPA Imaging Beads in the quantitative measurement of cAMP in cells

...say Adrenergic receptors are linked to adenylate cyclase via either inhibitory or stimulatory G pro...neration of cAMP. In response to receptor binding, adenylate cyclase converts AMP to cAMP, which exerts its eff...ponse to stimulation by forskolin, an activator of adenylate cyclase. The cells have responded in a dose depend...

The Bio-Rad Silver Stain, Rev E

...ins, Proc Natl Acad Sci USA 82, 52085212 (1985) 12. Coussen F et al., Identification of the catalytic subunit of brain adenylate cyclase: a calmodulin binding protein of 135 kDa, Proc Natl Acad Sci USA 82, 6736-6740 (1985) 13. Crooks AJ et al., The purificat...

Translate High Yields of Biologically Active Proteins

...ocol. The proteins analyzed were dihydrofolate reductase (DHFR), adenylate kinase 1 (AK1), carbonic anhydrase 2 (CA2), caspase 3 (CASP3), a...successive decrease of absorbance of NADPH at 340 nm at 30C [1]. adenylate kinase 1 (AK1): Activity was measured by a luciferase-based ATP ...

TransMessenger Transfection Reagent Handbook

...ncorporated into an in vitro-transcribed RNA by adding an RNA cap-structure analog to the transcription reaction. A poly-A tail, a stretch of adenylate residues added 3' to the mRNA coding sequence, also stabilizes mRNA. A poly-A tail can be incorporated into an in vitro-transcribed ...

In Vivo Signal Transduction Pathway Reporting Systems

... be activated by ultraviolet irradiation, and the PathDetect CREB system was activated by known PKA-activating agents such as the adenylate cyclase toxin from Bordetella pertussis and forskolin (data not shown). Applications of the PathDetect Systems The PathDetect c-Jun...

Enzyme Immunoassay for Studying Intracellular Levels of cAMP

... Sensitive, nonradioactive cyclic-AMP detection kit and adenylate cyclase (AC) toxin Danny Q. Hoang Stratagene Cloning Syste...AC Toxin for Increased Intracellular cAMP Levels Stratagene is offering adenylate cyclase (AC) toxin, a useful reagent for increasing intracellular cAMP le...
Adenylate in Biological Products

Chicken Anti-Human Adenylate kinase isoenzyme 6 Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description: Adenylate kinase isoenzyme 6...
Company:GenWay Biotech, Inc.
Adenylate in Biological Definition

Enzyme

...h covalent bonds The complete nomenclature can be browsed at http://www.chem.qmul.ac.uk/iubmb/enzyme/ Enzymes and classes of enzyme adenylate cyclase : participate in signal transduction by converting ATP into cyclic AMP Alcohol dehydrogenase : breaks down alcohols to aldehydes ...
Adenylate in Biological Dictionary

Isozyme

...zyme variation have revealed three ... The European Bioinformatics Institute ... This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase) ... Isozyme loci can be particularly useful for marking linkage groups (Tanksley and ... such as trees, may ...
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