Scientists learn why even treated genital herpes sores boost the risk of HIV infection

...they have been treated with oral doses of the drug acyclovir and have healed and the skin appears normal. These...ection increases the risk of acquiring HIV and why acyclovir treatment does not reduce that risk," says NIAID D...tment of such genital herpes lesions with the drug acyclovir does not reduce the risk of HIV infection posed by...

Herpes medication does not reduce risk of HIV transmission

... the first to determine whether twice daily use of acyclovir by individuals who are infected with both HSV-2 an...n outside partner, there were 41 infections in the acyclovir arm and 43 in the placebo arm not a significant difference. acyclovir suppressive treatment reduced the frequency of gen...

Herpes drug inhibits HIV replication, but with a price

... The anti-herpes drug acyclovir can also directly slow down HIV infection by targe... a risk though, as HIV-infected cells treated with acyclovir promote the emergence of multi-drug resistant HIV ...ing their interaction, recent studies showing that acyclovir treatment could reduce HIV viral load in co-infect...

New Hope Against the Cold Sore Virus

...nerve cell, "it binds to the microRNAs and inhibits their function," she explained. The virus is then allowed to activate. "Then one of the drugs like acyclovir should be able to handle the infection," Umbach said. That strategy appears to be working in the test tube at least. "There are animal trials under...

Transport's Phase 2 Data Show Single Treatment SoloVir(TM) ETS Significantly Stops Progression of Cold Sore Episode

...tridges containing Transport's novel, five-percent acyclovir gel. This unique study was designed to determine...-minute iontophoretic application of either active acyclovir gel or placebo gel. A second, investigator-supervi...S, utilizes the company's proprietary five-percent acyclovir gel formulation to treat herpes labialis, or cold ...

Antiviral Won't Improve Bell's Palsy Outcome

...AY, Oct. 17 (HealthDay News) -- The antiviral drug acyclovir is no better at easing a form of facial paralysis ...nal treatment, a new study finds. The fact that acyclovir may not be a new, improved treatment option comes ...ly change practice" by convincing doctors to avoid acyclovir when treating Bell's palsy, said Gilden, who co-au...

A Collaboration to Find New Tools to Fight Leukemia

...ut previously untreated patients. Patients in the study also received one year of prophylactic sulfamethoxazole-trimethoprim (anti-infection drug) and acyclovir (antiviral drug) along with the PCR treatment. The researchers reviewed study participants’ prognostic status and divided the patients into risk...

Genetic susceptibility in viral encephalitis

... of all viral encephalitis cases, according to the University of Maryland Medical Center. Before the advent of anti-viral drugs vidarabine in 1973 and acyclovir in 1981, mortality rates reached up to 70 percent. While the introduction of anti-viral treatment has been a boon to patients, brain damage still pose...

Antiviral Drugs May Be Useful For Easing Shingles Pain

...er gave antiviral treatment to 12 men and three women with moderate to severe pain following shingles. The patients received 10 milligrams of the drug acyclovir intravenously every eight hours for 14 days. They then took three 1,000-milligram pills of the drug valacyclovir per day for one month. The pati...

Oral Medication Effective In Combating Eye Infection

..., 14 patients in the first group (78 percent) and eight in the second group (36 percent) had recurrences. Thus researchers conclude treatment with acyclovir continues to be effective over the long-term in patients with ocular herpes simplex virus. ...

Acyclovir in Medical Technology

Durezol(TM) in the Treatment of Uveitis and Ganciclovir in the Treatment of Herpetic Keratitis: Studies of Treatments for Leading Causes of Blindness to Be Presented

... poster, "Data from Trials Evaluating Ganciclovir Ophthalmic Gel, 0.15% and acyclovir Ophthalmic Ointment, 3% for Herpetic Keratitis," is part of AAO Poster Sess... of data from three Phase 2 trials and one Phase 3 trial of ganciclovir and acyclovir for herpetic keratitis confirms the efficacy of ganciclovir for treatment o...

Emisphere Technologies, Inc. Announces 2007 Third Quarter Financial Results

... was filed by Genta Incorporated on gallium on July 31, 2007 -- A program continues on an improved oral formulation of the antiviral compound acyclovir with a pharmaceutical company outside of the United States -- Satiety and oral glucose challenge studies for both GLP-1 and PYY will be under...

Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results

...ed by Genta Incorporated on gallium nitrate on July 31, 2007 -- A program continues on an improved oral formulation of the antiviral compound acyclovir with a pharmaceutical company outside of the United States -- A food-intake study for both GLP-1 and PYY will be undertaken later this year a...

Acyclovir in Medical Dictionary

Gingivostomatitis

...ses blisters in ... Gingivostomatitis . Gingivostomatitis is an infection ... Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M. acyclovir for treating primary herpetic gingivostomatitis . Cochrane Database of Systematic Reviews ... ...

Acyclovir in Biological News

Herpes drug inhibits HIV in patients infected with both viruses

... acquire HIV." Though it was long-believed that acyclovir was an ineffective drug against HIV, it was often ...overed that in the presence of herpes virus HHV-6, acyclovir actually attacks HIV directly and is able to suppress its reproduction. acyclovir is a "prodrug," which is converted into its active...

Acyclovir in Biological Technology

China Sky One Medical, Inc. Obtains Production Approval for Two New Drugs

...that it recently obtained production approval from the State Food and Drug Administration (SFDA) in China for two of its newly developed drugs. acyclovir gel is used to treat the skin infection due to varicella-zoster virus and the herpes simplex virus. Shuanghuanglian suppositories helps relieve cold a...

Sirion Therapeutics New Drug Application for Ganciclovir is Accepted for Review by the FDA for the Treatment of Ocular Herpes

..., four randomized, multicenter trials compared ganciclovir gel, 0.15%, with acyclovir ointment, 3%, both of which are used as first-line therapies outside the U....t herpetic keratitis. The studies found that ganciclovir is as effective as acyclovir and that the tolerability of ganciclovir was superior to acyclovir, particu...

Emisphere Technologies, Inc. Announces 2007 Fourth Quarter and Year End Financial Results

...plication was filed by Genta Incorporated with the FDA on Gallium on July 31, 2007; a Gallium Phase I study began in third quarter 2007 -- An acyclovir study will generate data in the second quarter 2008 that we and a partner will review -- Satiety and oral glucose challenge studies for both GLP-...

Transport Pharmaceuticals Receives Coveted Frost & Sullivan Technology Innovation Award

... the delivery of the company's novel five- percent acyclovir gel formulation by means of electric current via a...), utilizes the company's proprietary five-percent acyclovir gel-formulation to treat herpes labialis, or cold ...trex(R) requires more than two hours to reach peak acyclovir levels in the skin. In a recently completed Phas...

Immtech and BioAlliance Sign Licensing Agreement for Pafuramidine

...I clinical development in oropharyngeal candidiasis in the USA. In addition, two other innovative products are currently in phase III clinical trials: acyclovir Lauriad(R) in oral herpes (based on the same Lauriad(R) muco-adhesive technology as Loramyc(R), which enables targeted release at the disease site) an...