Novel mechanisms controlling insulin release and fat deposition discovered
...ls was reduced by the actions of the growth factor activin B through the ALK7 receptor, and that blood glucose levels regulates the expression of both activin B and ALK7. In agreement with these results, mice lacking activin B also developed hyperinsulinemia to a similar ext...Liver fibrosis will be treated by a potential target
... problem. Previous studies have demonstrated that activin A is involved in hepatic fibrosis formation. Howev...sm of the fibrotic process is not well understood. activin receptor-interacting protein 2 (ARIP2) has been recently identified as a negative regulator of activin signal pathways. The fact that ARIP2 is highly exp...Key Signaling Molecules in New Teeth Formation Identified
... form a complex regulatory network with epithelial signals. They also show that spatial differences in the expression levels of two key genes, activin and Follistatin, contribute to the characteristic asymmetry of rodent incisors, which are covered by enamel only on their labial (front) side. ...Acceleron Pharma's ACE-031 Increases Muscle Mass and Strength in Preclinical Studies
...leron compounds consistently demonstrate substantial increases in skeletal muscle mass and strength." ACE-031, a protein therapeutic based on the activin receptor type IIB (ActRIIB), is the first of several compounds Acceleron is developing for the treatment of diseases involving the loss of muscle mass...Accelreon Pharma's ACE-031Shown to Increase Muscle Mass in Preclinical Studies
...muscle mass and strength.² ACE-031, a protein therapeutic based on the activin receptor type IIB (ActRIIB), is the first of several compounds Acceleron is...2; Study Findings The presentation, entitled ³Treatment with a Soluble activin Receptor IIB Causes Increased Muscle Mass and Strength in mdx Mice² di...UCSD researchers maintain stem cells without contaminated animal feeder layers
...y culture media enriched by a human protein called activin A are capable of maintaining human embryonic stem ...the results were narrowed to three molecules, with activin A, a protein that participates in cellular growth ... the researchers noted that "the identification of activin A as a key factor in mediating these cellular even...Rat Anti-Mouse Activin RIB / ALK-4 Monoclonal Antibody, Unconjugated, Clone 207304 from R&D Systems
Description: Mouse Activin RIB/ALK-4 MAb (Clone 207304)...Free Activin B ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...Free Activin AB ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...Free Activin A ELISA Kit from Diagnostic Systems Laboratories, Inc.
Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...