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Activin in Medical News

Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success

...0S proteasome; polyamine; 5T4 oncofetal antigen; a disintegrin and metalloproteinase domain 17 (ADAM17), TACE; acidic fibroblast growth factor (aFGF); activin receptor IIA (ActrIIA); adenosine deaminase; adenosine monophosphate (AMP); alpha5beta1 integrin; alphanubeta3 integrin; alphanubeta5 integrin; alpha-...

Novel mechanisms controlling insulin release and fat deposition discovered

...ls was reduced by the actions of the growth factor activin B through the ALK7 receptor, and that blood glucose levels regulates the expression of both activin B and ALK7. In agreement with these results, mice lacking activin B also developed hyperinsulinemia to a similar ext...

Liver fibrosis will be treated by a potential target

... problem. Previous studies have demonstrated that activin A is involved in hepatic fibrosis formation. Howev...sm of the fibrotic process is not well understood. activin receptor-interacting protein 2 (ARIP2) has been recently identified as a negative regulator of activin signal pathways. The fact that ARIP2 is highly exp...

Key Signaling Molecules in New Teeth Formation Identified

... form a complex regulatory network with epithelial signals. They also show that spatial differences in the expression levels of two key genes, activin and Follistatin, contribute to the characteristic asymmetry of rodent incisors, which are covered by enamel only on their labial (front) side. ...
Activin in Medical Technology

Acceleron Pharma's ACE-031 Increases Muscle Mass and Strength in Preclinical Studies

...leron compounds consistently demonstrate substantial increases in skeletal muscle mass and strength." ACE-031, a protein therapeutic based on the activin receptor type IIB (ActRIIB), is the first of several compounds Acceleron is developing for the treatment of diseases involving the loss of muscle mass...

Accelreon Pharma's ACE-031Shown to Increase Muscle Mass in Preclinical Studies

...muscle mass and strength.² ACE-031, a protein therapeutic based on the activin receptor type IIB (ActRIIB), is the first of several compounds Acceleron is...2; Study Findings The presentation, entitled ³Treatment with a Soluble activin Receptor IIB Causes Increased Muscle Mass and Strength in mdx Mice² di...

Research Documents Scalable Production, Survival Following Engraftment and Positive Impact on Cardiac Function in Infarcted Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for Heart Failure

...igodendroglial progenitors. Moreover, studies showed that GRNOPC1 secretes specific neurotrophic factors, including midkine, hepatocyte growth factor, activin A, transforming growth factor Beta and brain-derived neurotrophic factor. These factors induce growth of neurons and are likely to contribute to the t...
Activin in Medical Products

Free Activin AB ELISA Test

Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin A ELISA Test

Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin B ELISA Test

Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...
Company:Diagnostic Systems Laboratories, Inc.

MIS/AMH ELISA Test

Description:...ked by disulfide bridges (1). MIS/AMH belongs to the transforming growth factor-? (TGF-?) superfamily which includes TGF-? and the various inhibin and activin glycoproteins (2). All members of this superfamily are dimeric glycoproteins, and all are involved in the regulation of tissue growth and differentiat...
Company:Diagnostic Systems Laboratories, Inc.
Activin in Medical Dictionary

Hypogonadism

...ical term for a defect of the reproductive system that results in lack of function of the gonads . The gonads have two functions: to produce hormones, activin and to produce gametes (eggs or sperm). Deficiency of sex hormones can result in defective... Male hypogonadism — Comprehensive overview covers ...
Activin in Biological News

UCSD researchers maintain stem cells without contaminated animal feeder layers

...y culture media enriched by a human protein called activin A are capable of maintaining human embryonic stem ...the results were narrowed to three molecules, with activin A, a protein that participates in cellular growth ... the researchers noted that "the identification of activin A as a key factor in mediating these cellular even...
Activin in Biological Products

Rat Anti-Mouse Activin RIB / ALK-4 Monoclonal Antibody, Unconjugated, Clone 207304 from R&D Systems

Description: Mouse Activin RIB/ALK-4 MAb (Clone 207304)...
Company:R&D Systems

Free Activin B ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin AB ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin A ELISA Kit from Diagnostic Systems Laboratories, Inc.

Description: Activins are polypeptide hormones which belong to the transforming growth factor- (TGF-) superfamily. The TGF- superfamily is a large group of extra-cellular growth factors which control many aspects of development, reproductive function and tumor formation (1). Other members incude TGF-s, bone mor...
Company:Diagnostic Systems Laboratories, Inc.
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