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activator in Medical News

New Seminar Series from Activator Methods Teaches Doctors a Unique Approach to Improving Nation's Chiropractic Care: Focus on the Patients

PHOENIX, Sept. 19 /PRNewswire/ -- Activator Methods International ( http://www.activator.com ), pioneer in chiropractic instrument manufacturing and technique training for 40 years, has formed an alliance with three leading chiropractic companies to create the Activator Advantage seminar serie...

Amgen's Second Quarter 2009 Adjusted Earnings Per Share Increased 13 Percent To $1.29

...its option to the worldwide rights (excluding Japan) of Cytokinetics' cardiac contractility program, which includes CK-1827452, a novel cardiac myosin activator being developed for the treatment of heart failure. Emerging Pipeline: The Company provided an update on several of its clinical programs: ...

Immune Response May Speed AIDS Progression in Women

... the recognition of HIV-1 responds to the virus differently in women than in men. This then leads to differences in chronic T-cell activation, a known activator of disease progression, according to the researchers at the Ragon Institute of MGH, MIT and Harvard. "This study may help to account for reported g...

Fate Therapeutics to Present Data on Stimulation of Osteogenic Activity Using Small Molecule Modulators of Wnt Pathway

...ber of bone injuries and conditions including non-union fracture, spinal fusion or osteoporosis. The Company's poster entitled, "A small molecule activator of the canonical Wnt pathway stimulates differentiation of mesenchymal stem cells to an osteoblast phenotype," will be presented by Scott Thies, Ph.D....

Sangamo BioSciences Presents Positive Phase 2 ZFP Therapeutic Data at ADA 2009

...udy (Abst# 859-P): "Vascular Endothelial Growth Factor Zinc Finger Protein activator (SB-509) in Mild to Moderate Diabetic Peripheral Neuropathy Patients. Inter...rve Conduction Using Vascular Endothelial Growth Factor Zinc Finger Protein activator (SB-509): Interim Phase 2 Results (SB-509-0701 Study)" presented on Sunday,...

Window for Stroke Treatment Opens Wider

...rrent recommendation, which set a three-hour deadline for the medication's use. The review of 1,622 cases of people treated with tissue plasminogen activator (tPA) in four separate studies finds that the benefit in keeping brain cells alive outweighs the risk of brain-damaging bleeding when the drug is give...
activator in Medical Technology

Debiopharm Group and Mercury Therapeutics, Inc. Sign an Exclusive License Agreement for the Development and Commercialisation of Debio 0930

...iovascular disease, announce the signature of an exclusive license agreement for the development and commercialisation of Debio 0930, a small molecule activator of AMPK (adenosine monophosphate activated protein kinase) for the treatment of diabetes and metabolic diseases. Activation of AMPK has been shown to ...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

...ients for the treatment of these devastating diseases." About Talactoferrin Talactoferrin is a novel targeted dendritic cell recruiter and activator (DCRA) being studied for the treatment of several life-threatening diseases including RCC and NSCLC. Talactoferrin mediates its anti-cancer activity ...

D-Pharm Submits Investigational New Drug Application and Special Protocol Assessment to the FDA for Phase III Trial of DP-b99 in Acute Stroke Patients

... to the American Heart Association, the estimated direct and indirect cost in 2009 of stroke in the US is $68.9 billion. Other than tissue plasminogen activator (tPA), which must be administered 3 hours after stroke, there are no FDA approved medicines for this indication. About D-Pharm Ltd. D-Ph...

Schering-Plough's Investigational Oral Thrombin Receptor Antagonist Meets Primary Endpoint in a Newly Published Study

...at initiate aggregation and clot formation, and thrombin is the most potent activator of platelets. Drugs that block platelet activation by other mechanisms, suc...el agents that specifically modify the actions of thrombin, the most potent activator of platelets. TRA binds selectively to the thrombin receptor on platel...

Results of NeuroThera Effectiveness and Safety Trial - 2 (NEST-2) Presented at International Stroke Conference 2009

...ents were eligible for inclusion in the study if they were 40-90 years of age, had moderate to severe strokes, and had not received tissue plasminogen activator (tPA). Initiation of treatment had to occur within 24 hours after stroke onset. In NEST-2, TLT achieved a favorable outcome in 36.3% of patients...

Why Wait for an Anti-Aging Drug? Researchers Interviewed on CBS-TV's 60 MINUTES Discover Longevinex(R) Nutriceutical Matrix Activates 9-Fold More Longevity Genes than Plain Resveratrol

...those found in 3-5 glasses of red wine, or in Longevinex(R) (100 mg resveratrol), appear to be more efficacious. The idea of a mega-Sirtuin1 gene activator (1000-fold gene booster), such as proposed by a pharmaceutical company, requires greater scrutiny because an engineered molecule that has never been u...
activator in Medical Products

Plasminogen Activator Inhibitor 1, Activity

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

PTT-LA

Description:... Lupus Anticoagulant-Sensitive APTT Reagent.Cephalin with particulate activator (silica), freeze-dried....
Company:Diagnostica Stago, Inc.

STA STACLOT PROTEIN C

Description:... human plasma free of Protein C; highly purified extract of Agkistrodon c. contortrix venom for specific activation of protein C, freeze-dried with an activator selected specially for protein C assay....
Company:Diagnostica Stago, Inc.

STA STACHROM PROTEIN C

Description:...of Protein C Activity by STA© Analyzers. Highly purified extract of Agkistrodon c. contortrix venom for specific activation of protein C, with an activator selected specially for protein C assay....
Company:Diagnostica Stago, Inc.

ASSERACHROM TPA

Description:... Enzyme Immunoassay of Tissue Plasminogen activator Antigen by ELISA Method, 96 tests....
Company:Diagnostica Stago, Inc.

VACUETTE Crossmatch tubes - Non-ridged (pull cap)

Description:... Cross-match tubes are available in two versions. The cross-match serum tube contains a clotting activator and is suitable for cross-match tests where serum is required for testing material. The EDTA cross-match tube is suitable where the testing material r...
Company:Greiner Bio-One

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activator in Medical Definition

Ultrasound-enhanced systemic thrombolysis

...tive intracranial blood flow may help expose thrombi to tissue plasminogen activator . Studies have shown that complete recanalisation or dramatic clinical re... See also Ultrasound Stroke tissue plasminogen activator ...
activator in Medical Dictionary

Chiropractor

...stablished since 1990. Set up your appointment today for a chiropractor who will get you back on your feet. Call now. Welcome to home of Boise's activator chiropractor , Dr. Ed Rabin. ... families, athletes and seniors - and, sometimes, even other Boise chiropractors . ... Chiropractor , Dr. Hea...
activator in Biological News

Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes

Researchers at the University of Vermont Cardiovascular Research Institute, Colchester, Vermont have found that increased expression in the heart of plasminogen activator inhibitor type-1 (PAI-1) is profibrotic. The results, which appear in the March 2009 issue of Experimental Biology and Medici...

Proteasome activator enhances survival of Huntington's disease neuronal model cells

To function, each living cell needs both to build new and to degrade old or damaged proteins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins. When proteins or peptides mutate, they can present major problems ...

Protein handlers should be effective treatment target for cancer and Alzheimer's

... help explore the large family of molecular chaperones. For contrast, they also have a mouse that over expresses heat shock factor 1, or Hsf1, a major activator of molecular chaperones. They are now focusing on developing mice that lack molecular chaperones or heat shock factors in targeted areas, such as ...

Experimental treatment halts hypoxic-ischemic brain injury in newborns

...blocking the brain enzyme, tissue-type plasminogen activator (tPA), prevents progressive brain damage triggered...a naturally occurring substance called plasminogen activator inhibitor-1 (PAI-1) into the brains of newborn rat... Besides demonstrating the brain's plasminogen activator system plays a pivotal role in neonatal cerebral h...

Fate in fly sensory organ precursor cells could explain human immune disorder

... cells. Bellen and colleagues have found that the Arp2/3 complex and its activator WASp (Wiskott-Aldrich syndrome protein) function in these daughter cells to...h Wiskott-Aldrich syndrome have mutations in a gene called WASp. WASp is an activator of the Arp2/3 complex. In our work we found that WASp is also required for ...

Enzyme doesn't act alone in atrial fibrillation

...ere had to be another factor that contributed to arrhythmias." Wehrens said they discovered that a sudden increase in heart rate is a very specific activator of calmodulin kinase II. The research team found that mice with the mutation were more prone to atrial fibrillation after their heart rate was sped up...
activator in Biological Technology

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... antibody optimized to block a key signaling pathway in cancer stem cells. Specifically, OMP-21M18 selectively targets Delta-like ligand 4 (DLL4), an activator of Notch signaling, which is a pathway known to be important in stem cells and cancer. Blocking DLL4 results in broad-spectrum anti-tumor activity vi...

D-Pharm Receives FDA Clearance to Commence a Phase III Trial of DP-b99 in Acute Stroke Patients

...st in 2009 of stroke in the US is $68.9 billion. Only about 2 to 5% of acute stroke patients are eligible for treatment with tissue plasminogen activator (tPA), the only FDA approved drug treatment for acute stroke. About D-Pharm Ltd. D-Pharm ( http://www.dpharm.com ) is a clinical stage, ...

Amgen Exercises Option for Exclusive License to Cytokinetics' Cardiac Contractility Program That Includes CK-1827452

...ractility program. The license includes CK-1827452, a novel cardiac myosin activator being developed for the treatment of heart failure. Under the terms of...tion with Amgen to provide for the advancement of this novel cardiac muscle activator into studies that are designed to further assess the clinical benefit of th...

Ascenta Therapeutics Announces Results of Preclinical Evaluation of AT-406 in Multiple Cancer Models

...ivates enzymes called caspases to initiate breakdown of the cancer cell. AT-406 is thought to mimic the activity of Smac (second mitochondria-derived activator of caspases) by binding to XIAP and preventing it from inhibiting caspase activation. Upon binding, AT-406 induces rapid degradation of cIAP-1/2 prot...

Cardium Announces FDA 510(K) Clearance of InnerCool's RapidBlue(TM) Endovascular System

...imately 700,000 Americans experience a stroke each year, and a comparable number of patients are affected outside the U.S. Although tissue plasminogen activator (tPA) has been shown to lessen damage associated with a stroke, particularly if it can be administered within three hours of onset, many stroke patien...

Sonus Pharmaceuticals and OncoGenex Technologies complete business combination; OncoGenex Pharmaceuticals to commence trading on NASDAQ Capital Market today

...rogress is being made to determine its safety and pharmacokinetic profile, in addition to the maximum tolerated dose; - CSP-9222 is a caspase activator presently in pre-clinical development. Caspase activators consist of small molecules that have been identified in preclinical research as ac...
activator in Biological Products

Plasminogen Activator Inhibitor (PAI-1) Colorimetric Assay Kit from AMERICAN DIAGNOSTICA

Description: Spectrolyse (pL) PAI kit is a two-stage indirect enzymatic assay for the quantitative determination of Plasminogen Activator Inhibitor (PAI-1) activity in plasma. Sample Type: plasma...
Company:AMERICAN DIAGNOSTICA

Xylene Resistant (X/R) Red System, 1000 Tests (SIGNET) from Covance Research Products, Inc

Description:... Signets Xylene Resistant (X/R) Red System consists of concentrated X/R Red Chromogen, X/R Red activator and X/R Red Buffer. The X/R Red solution reacts with alkaline phosphatase to produce red staining that may be permanently mounted. Kit Contains...
Company:Covance Research Products, Inc

Smac/DIABLO, Human, Recombinant, E. coli from Calbiochem

Description:... Second Mitochondria Derived activator of Caspase/DIABLO Liquid. In 100 mM KCl, 20 mM HEPES, pH 7.5 AVOID FREEZE/THAW CYCLES. Amino acid residues 56 - 239 of human Smac/DIABLO with a carb...
Company:Calbiochem

Anti-Cullin-3 (CUL-3) Ab-1 Polyclonal Antibody, Unconjugated from Lab Vision

Description:...qutinnn ligase. It forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by protesomes. Cyclin E is an activator of cdk2, which leads the cell to S phase. Cul-3-/- mice show increased accumulation of Cyclin E protein and disruption of normal cell cycle regulation...
Company:Lab Vision

Anti-JIP 1 / 2 (SH3) Polyclonal Antibody, Unconjugated, Clone ZMD.177 from Invitrogen

Description:...38 MAP kinases; it has also demonstrated selectivity in its binding to specific proteins of the JNK pathway. In addition to JNK, JIP1 binds to the JNK activator MKK7 (MAP kinase kinase 7) and the MKK7 activators MLK3 (mixed-lineage protein kinase 3) and DLK (dual leucine zipper-bearing kinase), all at separate...
Company:Invitrogen
activator in Biological Definition

Alcohol

...alides , where the hydroxyl group is replaced by a chlorine atom. If primary or secondary alcohols are to be reacted with hydrochloric acid , an activator such as zinc chloride is needed. Alternatively the conversion may be performed directly using thionyl chloride . [1] Alcohols may likewise...

Apoptosis

... stimulus, IAP activity is relieved after SMAC (Second Mitochondria-derived activator of Caspases, or its mouse homolog, called DIABLO), a mitochondrial protei... to the processed form of caspase-9, and suppress the activity of apoptotic activator cytochrome c (see previous section on biochemical execution). The apopto...

Morphogenesis

...l cytoplasm. Gene expression in these nuclei is regulated by the Bicoid, Hunchback, and Caudal proteins. For example, Bicoid acts as a transcriptional activator of hunchback gene transcription. Segmentation Gap genes Gap genes The other important function of the gradients of Bicoid...

Morphogenesis

...l cytoplasm. Gene expression in these nuclei is regulated by the Bicoid, Hunchback, and Caudal proteins. For example, Bicoid acts as a transcriptional activator of hunchback gene transcription. Segmentation Gap genes Gap genes The other important function of the gradients of Bicoid...
activator in Biological Dictionary

Promoter site

...are trademarks of Satmetrix Systems, Inc. ... promoter n. One that promotes, especially an active supporter or advocate. ... promoter DNA by an activator protein binding to its own DNA binding site nearby. ... Meaning of Promoter site as a legal term. What does Promoter site mean in law? ...

Positive interference

... RF has been shown to eliminate the false positive interference with the MEIA ... Positive interference in lithium determinations from clot activator in ... We describe positive interference with the ion-selective electrode determination ... Today, labs rely chiefly on competition immunoassay...

Caspase

... "Role of FLASH in caspase -8-mediated activation of NF-kappaB: dominant-negative ... "The atomic-resolution structure of human caspase -8, a key activator of apoptosis. ... Caspase -3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, ... Activation of caspase -3 requires proteo...

AP-1

... In the field of molecular biology, the activator protein 1 ( AP - 1 ) is a transcription factor which is a heterodimer... I established clones ... clones with phorbol dibutyrate (PDB), a known activator of AP - 1 , rapidly ... Regulation of AP - 1 is complex and occurs at...

Allosteric site

...unctionally coupled to the active site , such that ... ... allosteric activator binds to the enzyme at the regulatory site , the ... will remain activated until the allosteric activator leaves the regulatory site . ... Allosteric Site - BioPortfolio - I...
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Breaking Medicine News(10 mins):Health News:Scientists show type-1 and type-2 diabetes are caused by same underlying mechanism 2Health News:WEDI Releases Full Conference Agenda for Its Annual Fall Conference – WEDI-Con 2014 2Health News:WEDI Releases Full Conference Agenda for Its Annual Fall Conference – WEDI-Con 2014 3Health News:MetroMD Offers Revolutionary Anti-aging Hormone Therapy in Hollywood Area 2Health News:National Association of Hispanic Nurses (NAHN) Receives Five-Year Federal Grant from the National Institutes of Health (NIH) 2Health News:National Association of Hispanic Nurses (NAHN) Receives Five-Year Federal Grant from the National Institutes of Health (NIH) 3
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Breaking Biology News(10 mins):New textbook introduces undergraduates to mathematics for the life sciences 2UTSA researcher awarded $38K+ to evaluate energy efficiency options for historic homes 2UTSA researcher awarded $38K+ to evaluate energy efficiency options for historic homes 3How steroid hormones enable plants to grow 2
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