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Acrolein in Medical News

Researchers use nanoparticles to deliver treatment for brain, spinal cord injuries

.... "Acrolein is the most poisonous of these toxins. It's an industrial hazard for which hydralazine is an antidote." Borgens and his team introduced acrolein into cells and then treated the cells with different combinations of hydralazine and/or PEG delivered by the mesoporous silica nanoparticles. They ...

Acrolein may be the key to halting spinal cord damage

...or several days after a traumatic injury. Although acrolein is produced by the body and is non-toxic at normal...l Engineering. "Our latest research indicates that acrolein may be the primary culprit that enables this vicious cycle. Because acrolein has already been implicated in cancer and neurolog...
Acrolein in Medical Technology

ZIOPHARM Presents ZIO-201 Lymphoma Data at ISH

...erse cancer models. Unlike IFOS which is a pro-drug, ZIO-201 is directly active against cancer cells. Also, unlike IFOS, ZIO-201 is not metabolized to acrolein or chloracetaldehyde which cause bladder or central nervous system toxicities. ZIO-201 continues in a phase I trial in diverse cancers exploring maxim...

ZIOPHARM Presents Data on Orally Active ZIO-201 at AACR

...rse cancer models. Unlike IFOS, which is a pro-drug, ZIO-201 is directly active against cancer cells. Also, unlike IFOS, ZIO-201 is not metabolized to acrolein or chloroacetaldehyde which cause bladder or central nervous system toxicities. ZIO-201 continues in a phase I trial in diverse cancers exploring maxi...

Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology

...rse cancer models. Unlike IFOS, which is a pro-drug, ZIO-201 is directly active against cancer cells. Also, unlike IFOS, ZIO-201 is not metabolized to acrolein or chloroacetaldehyde which cause bladder or central nervous system toxicities. ZIO-201 continues in a phase I trial in diverse cancers exploring maxi...
Acrolein in Biological News

Purdue scientists may have found key to halting spinal cord damage

...or several days after a traumatic injury. Although acrolein is produced by the body and is non-toxic at normal...l Engineering. "Our latest research indicates that acrolein may be the primary culprit that enables this vicious cycle. Because acrolein has already been implicated in cancer and neurolog...
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