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Aberrations in Medical News

Occupational Exposure To Radiation Causes Chromosome Aberrations

Professor Manoor Prakash Hande and his colleagues from National University of Singapore studied the effect of plutonium exposure and risk of developing Chromosomal aberrations leading to cancer// in Plutonium plant workers. The study is mainly aimed at identifying biomarkers for easy detection an...

NUCYNTA(TM) (tapentadol) CII Immediate Release Tablets Now Available for Relief of Moderate to Severe Acute Pain

...ntal-status changes (eg, agitation, hallucinations, coma), autonomic instability (eg, tachycardia, labile blood pressure, hyperthermia), neuromuscular aberrations (eg, hyperreflexia, incoordination) and/or gastrointestinal symptoms (eg, nausea, vomiting, diarrhea). Withdrawal symptoms may occur if NUCYNTA(T...

St. Jude Scientist Named Pew Scholar

...ho ensure the future success of St. Jude." Mullighan's research focuses on the use of high-resolution, genome-wide approaches to identify genomic aberrations contributing to leukemogenesis and influencing leukemia outcome; the use of in vitro and in vivo experimental approaches to model genomic abnormal...

Dream team targets key driver for breast, ovarian, endometrial cancers

...hat we learn in women's cancers will apply to many other types." Genetic aberrations in the network, known as the PI3K pathway, are found in half of all breast ...ple to detect cancer-related genetic mutations, study the effect of genetic aberrations on the PI3K pathway and on PI3K inhibitors used in clinical trials, and ide...

UH optometrists make custom contact lenses for long-underserved patients

...ducts that will be available for widespread clinical use. "Every eye has aberrations that cannot be corrected with glasses," explained Dr. Raymond A. Applegate,...gid contact lenses, or gas-permeable ones, are used to correct higher-order aberrations in highly aberrated eyes by masking a significant portion of the aberration...

Medicare's 'No' on Virtual Colonoscopy Stirs Expert Debate

...ng to need a colonoscopy in order to remove polyps." He also seconded Fletcher's concern that virtual colonoscopy would pick up too many innocuous aberrations outside the colon. "Most of these are incidental and not important to the patient but result in tests that increase the cost and the risk to patients...

Study Results Published in CUTIS Demonstrate Long-Term Safety and Efficacy of Vectical(TM) (calcitriol) Ointment 3 mcg/g in the Management of Mild-to-Moderate Plaque Psoriasis

...sis, who are taking calcium or Vitamin D supplements, or who are on medications known to increase serum calcium levels, such as thiazide diuretics. If aberrations in parameters of calcium metabolism occur, Vectical(TM) Ointment should be discontinued until these normalize. Patients should be cautioned to avoid e...

ADA releases position paper on obesity, reproduction and pregnancy outcomes

...t the effect of a woman's nutritional status prior to pregnancy is an issue of great public health importance. "Among obese women, who already have aberrations in glucose and lipid metabolism, the further adjustments induced by hormonal changes in pregnancy create a metabolic milieu that enhances the risk for...

Gene Studies Reveal Cancer's Secrets

...of getting the disease are eight times higher than that of the general population," she noted. An earlier analysis identified seven DNA sequencing aberrations called "single nucleotide polymorphisms" (SNPs) that might lead to chronic lymphocytic leukemia. In the current study, researchers confirmed these fin...

Galderma Wins FDA Approval for Vectical(TM) Ointment, a Novel Topical Therapy for Mild-to-Moderate Plaque Psoriasis

...sis, who are taking calcium or Vitamin D supplements, or who are on medications known to increase serum calcium levels, such as thiazide diuretics. If aberrations in parameters of calcium metabolism occur, Vectical(TM) Ointment should be discontinued until these normalize. Patients should be cautioned to avoid e...
Aberrations in Medical Technology

Semafore's SF1126, a Vascular Targeted Pan-PI3K/mTOR Inhibitor, Is Well Tolerated and Demonstrates Activity in Phase I Solid Tumor Patients

..., endometrial, and prostate cancer patient each achieved durable stable disease for 20 weeks (5 mos.). These specific tumor types are associated with aberrations of the PI3K pathway that commonly lead to resistance and poor prognostic outcomes. Pharmacodynamic analysis of tumor tissue confirmed inhibitio...

New Phase 3 Study of Tapentadol Immediate Release Tablets Published in Current Medical Research and Opinion Journal

...-status changes (e.g., agitation, hallucinations, coma), autonomic instability (e.g., tachycardia, labile blood pressure, hyperthermia), neuromuscular aberrations (e.g., hyperreflexia, incoordination) and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea). Pregnancy-Category C. There are no ad...

Galderma Announces Interim Data Relating to Sequential Treatment Regimen of Clobex(R) Spray Followed by Vectical(TM) Ointment in Managing Plaque Psoriasis

...is, who are taking calcium or Vitamin D supplements, or who are on medications known to increase serum calcium levels, such as thiazide diuretics. If aberrations in parameters of calcium metabolism occur, Vectical(TM) Ointment should be discontinued until these normalize. Patients should be cautioned to avoid ...
Aberrations in Medical Products

MAXWELL Optical Wavefront Aberrometer

Description:...ive diagnostic instrument with a wide range of functions that permit eye care practitioners and researchers to effectively assess all of the wavefront aberrations present in a subjects eye. This remarkable device offers the widest wavefront diagnostic range and functions on more than 99% of subjects. Beyond its ...
Company:ZIEMER USA, Inc.

20D

Description:... Volks state-of-the-art 20D diagnostic/laser lens is perfectly corrected for field curvature, astigmatic aberrations and coma delivering the best retinal image of any 20 diopter lens on the market. Its advanced double aspheric design further maintains linear image m...
Company:Volk Optical, Inc.

OQAS Optical Quality Analysis System

Description:...is the ability of the OQAS to measure and analyze all orders of aberration PLUS scatter. Standard aberrometers are incapable of measuring higher order aberrations or scatter. To truly analyze your patients optical quality it is necessary to have complete information. Applications include: screening ...
Company:Visiometrics

KR-9000PW Wavefront Analyzer

Description:...and reliability. The instrument provides sphere, cylinder and axis measurements as well as indicating spherical aberrations, coma and other high order aberrations of the eye. With a measuring range of -25 to +22 diopters of sphere, the new KR-9000PW is a practical wavefront tool for use in the everyday practice....
Company:Topcon America Corporation

CFI Plan Apochromat Series for Brightfield/Phase Contrast (DM)

Description:... Featuring longer working distances with high Numerical Apertures, these objectives have been designed to correct all optical aberrations throughout the visible spectrum from violet to red from centre to edges across the entire 25mm field of view. They also offer superior image flatness ...
Company:Nikon

3D Wave

Description:... With the remarkable 3-D Wave, Marco gives you an instrument that can evaluate the patient's total optical system. Measuring both low and high-order aberrations on a single axis, the 3-D Wave gives you the power to diagnose patient complaints that simply would not be diagnosed before. Wavefront Aberrome...
Company:Marco Ophthalmic, Inc.

Z-View Aberrometer

Description:...actitioner. Utilizing a proprietary, non Hartmann-Shack technology (patents pending) the Z-View Aberrometer quickly and accurately measures high order aberrations (3rd-6th order), as well as sphere, cylinder and axis to arrive at a fully optimized prescription in less than a minute. This compact, flexible instru...
Company:Ophthonix, Inc.

Carl Zeiss WASCA Analyzer/Aberrometer

Description:...he optical properties of the entire eye from thecornea to the retina. In addition to refractive values, the WASCA Analyzer also supplies higher order aberrations which were largely ignored in the past. The WASCA Analyzer provides you with an objective result for an exact diagnosis. It will help you to select th...
Company:Carl Zeiss Meditec, Inc.

WaveScan Wavefront System

Description:... The WaveScan WaveFront System is an ophthalmic diagnostic instrument that measures the refractive error and wavefront aberrations of the human eye using a Hartmann-Shack wavefront sensor. The measurements can be used to determine regular (sphero-cylindrical) refractive errors and...
Company:Advanced Medical Optics, Inc. (AMO) - VISX

Zywave® II

Description:...echnology. Precisely measured. Zywave® II Wavefront Aberrometer offers precision diagnostics, measuring refractive error by identifying the total aberrations of the eye. As part of the Bausch & Lomb Zyoptix™ Diagnostic Workstation, Zywave II Wavefront Aberrometer provides patient-specific analysis tha...
Company:Bausch & Lomb Storz
Aberrations in Biological News

Chromosomal problems affect nearly all human embryos

...ntative of normal human embryogenesis, the process that begins once an egg has been fertilised. Using new technologies that can detect chromosomal aberrations in the whole genome (all human chromosomes) of a single cell, the team was able to screen embryonic cells at a much higher resolution than previously,...

Pliable proteins keep photosynthesis on the light path

...Lin, PhD, senior researcher at ASU's Department of Chemistry & Biochemistry and Biodesign Institute, and lead author of the study. "Carefully-designed aberrations provide extensive information about the normal mechanism of energy conversion in reaction centers, just like studying a disease clarifies the paramete...

Clarke clarifies pattern recognition theory

...a cognitive process rewarded by the faculty of humour. While this may seem counter-intuitive it is fundamental to an understanding of humour that such aberrations and deviations are discounted from the range of humorous causality." The apparent simplicity of the theory and the information-processing system i...

Genetic irregularities linked to higher risk of COPD among smokers

...n the Boston Early-Onset COPD study and a control group from the Normative Aging Study. The genome-wide association study revealed several genetic aberrations that might be linked to COPD. But after a series of statistical analyses, only two single letter changes in DNA - (called single nucleotide polymorph...

New tumor markers determine therapy intensity

...rom 340 patients and compared the documented course of disease with genetic aberrations in the tumor DNA. aberrations were seen at the chromosome level, the units in which the entire genetic in...

Duke-NIEHS team shows how DNA repairs may reshape the genome

...ow the damage was repaired. Most of the chromosome aberrations they identified resulted from interactions between...broken ends on the same chromosome. Chromosome aberrations are a change in the normal chromosome complement b...u may get a new species." The radiation-induced aberrations in yeast were initially detected by co-author Jim ...

Protein protects lung cancer cells from efforts to fix or kill them

... change them back into healthy cells -- or evade treatments designed to kill them. Cancer is frequently associated with the accumulation of genetic aberrations in cells chromosomes. If these damaged cells cant access their built-in repair system and subsequently survive long enough to divide and multiply, the...

Engineers demonstrate a new type of optical tweezer

...rs and could perform calibrated force measurements in a footprint of only 100x100┬Ám. Traditional tweezers, by contrast, would suffer from crippling aberrations in such locations. Moreover, in experimental trials, the optical tweezers exhibited trapping performance comparable to conventional optical tweezers w...

Gene elevating breast cancer risk also causes prostate cancer

... results of this international research effort were recently published in Nature. The research first involved comprehensive screening for genetic aberrations in 113 Finnish breast cancer families. The same constitutional mutation in PALB2 was observed in three families. It was later showed that the relevant...

Why is the heart heart-shaped?

...ernal forces (such as blood flow) is necessary to create the cell shapes that generate chamber curvatures. Disruption of this balance may underlie the aberrations observed in some types of heart disease. ...
Aberrations in Biological Technology

Leading Refractive Eye Surgery Experts from Trusted LASIK Surgeons Directory Educate Peers at ASCRS Annual Meeting

...study of "Repeatability of Anterior and Posterior Corneal Higher-Order aberrations in 4 mm, 6 mm, and 8 mm Diameters Measured by Pentacam System" (J. Woj...gh order aberrations" of which the above are just a part of the sum of aberrations (HOA's). Custom or high definition treatments rely on the measurement of t...

Stretchable silicon camera next step to artificial retina

...era. "Optics simulations and imaging studies show that these systems provide a much broader field of view, improved illumination uniformity and fewer aberrations than flat cameras with similar imaging lenses," said Rogers, who also is a researcher at the Beckman Institute and at the university's Frederick Seitz...

New technique measures ultrashort laser pulses at focus

...is distorted allows researchers to correct for the aberrations by changing a lens or using a pulse shaper or comp...ificantly from point to point in space due to lens aberrations in focusing optics. To address those issues, th...hibited mostly chromatic aberrations. Spherical aberrations occur when the light that strikes the edges of the...

STAAR Surgical's Collamer(R) IOL Designated as a New Technology Intraocular Lens by the Centers for Medicare and Medicaid Services

... IOLs. The STAAR Afinity Collamer Aspheric IOL has proven to reduce spheric aberrations leading to improved visual acuity and increased contrast sensitivity. Thi... IOL business is in the ASC segment. The NTIOL subset for Reduced Spherical aberrations to which the STAAR Afinity Collamer Aspheric IOL has been approved will all...

DMetrix and the Armed Forces Radiobiology Research Institute Announce Cooperative Research and Development Agreement

...today that they have entered into a cooperative research and development agreement to improve the speed and accuracy of detecting dicentric chromosome aberrations for radiation dose assessment. The agreement will integrate DMetrix's EX-40(R) high-throughput array microscope imaging system into AFRRI's automate...

New study reveals potential instability in stem cells

...ad several genetic flaws, with chromosomes misplaced, switched around or even deleted from the original cells. Eight out of the nine cell lines showed aberrations in the DNA sequence and replaced hydrogen atoms, making them more consistent with cancer cells than with stem cells. "The observation implies that...

The Affymetrix GeneChip Scanner 3000 New Advances in Scanner Design for Superior Performance, Reliability, and Dynamic Range

..., scanmotion control are the principle causes of geometric distortion. Lens aberrations and optical misalignment lead to non-uniform emission collection. Second, t..., used in the X and Y axes, accurately locate each fluorescent pixel. Optic aberrations and galvanometer imperfections no longer dominate scan linearity; thus, con...

The Flexible matriXarray Chip System: A New Perspective for Probe Optimization in Gene-Expression Profiling

... two probes. For the kidney- specific gene (GenBank acc. no. AF062389), probes 2, 5, 6, and 7 seem to be specific, while probes 1, 3, and 4 show aberrations in their intensity pattern. In an ongoing study, the expression levels of 130 genes in 5 different human tissues...
Aberrations in Biological Definition

Chromosome

...fferent species 5 Karyotype 6 Human chromosome 7 Chromosomal aberrations 8 See also 9 External links Chromosomes in eukaryotes ...rmined, as have a small number of unclonable gaps. [1] Chromosomal aberrations Some chromosome abnormalities do not cause disease in carriers, such as ...

Developmental biology

...nismal form in an evolutionary context. The findings of developmental biology can help to understand developmental malfunctions such as chromosomal aberrations , for example, Down syndrome . An understanding of the specialization of cells during embryogenesis may shield information on how to specialize st...

Karyotype

...es are arranged and displayed (often on a photo) in a standard format: in pairs, ordered by size. Karyotypes are examined in searches for chromosomal aberrations , and may be used to determine other macroscopically visible aspects of an individual's genotype , such as sex (XX vs. XY pair). The study of karyo...

Microscope

...d eyepiece assemblies. These multi-component lenses are designed to reduce aberrations , particularly chromatic aberration and spherical aberration . In modern...s a definite limit ( d ) to the optical resolution . Assuming that optical aberrations are negligible, the resolution ( d ) is given by: Usually, a &la...
Aberrations in Biological Dictionary

Lens

...his lens also boasts impressive close-up shooting capability, allowing users to ... Rags Int., Inc. Digital Photography ... Lens Distortion and aberrations Things that go bump in the night. Objective Lens Construction Putting it all together. ... A NIKKOR camera lens is a commitment to perfection, ...

Epigenetic

... Epigenetic : Methylation Specific Pcr resources and information at epigenetic .net. ... Epigenetic . Home Site Map Develop Your Domain Names ... aberrations in these epigenetic mechanisms are known to be associated with the ... Chromatin modifications impart epigenetic control of gene expression wi...

Dicentric

...icentric : ... dicentric : Merriam-Webster's Online Dictionary, 11th Edition [home, info] ... ... accidental exposure were studied for dicentric aberrations and micronuclei ... Please enter a Recipient Address and/or check the Send me a copy checkbox. ... We report a case of acute promyelocytic leukemia...
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(Date:4/17/2014)... chronic inflammation in non-cancerous prostate tissue may have nearly ... those with no inflammation, according to results of a ... Kimmel Cancer Center. , The link between persistent inflammation ... high-grade prostate cancer those with a Gleason score ... the most aggressive and rapidly growing prostate cancers. , ...
(Date:4/17/2014)... have identified new pain relief targets that could ... BBSRC-funded researchers at King,s College London made the ... in the periphery of the body. , Dr ... identifying mechanisms underlying pain generation and our findings ... side effects." , One potential side effect of ...
(Date:4/17/2014)... PLOS Pathogens , children who live in regions ... an immune response to infection with malaria parasites that ... fever and illness and partially control the growth of ... researchers develop future interventions that prevent or mitigate the ... approximately 200 million cases of malaria occur worldwide, resulting ...
(Date:4/17/2014)... Diego School of Medicine report that older women, plucky ... loss are more likely to be compassionate toward strangers ... in this month,s issue of the International Journal ... associated with better health and well-being as we age, ... the outcomes of individuals whose deficits in compassion put ...
(Date:4/17/2014)... in the April issue of Immunity , Kevin ... Medical Research, says it,s time to take a fresh ... sepsis, which kills millions worldwide every year, including ... released into the bloodstream to fight an injury or ... for maintaining good health without inflammation, wounds and ...
Breaking Medicine News(10 mins):Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:New pain relief targets discovered 2Health News:Study sheds light on how the immune system protects children from malaria 2Health News:The ilk of human kindness 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2
(Date:4/17/2014)... word for chili peppers. Information about archaeological remains of ... of the appearance of words for chili peppers in ... domesticated and highlight the value of multi-proxy data analysis. ... of nine papers presented in a special feature issue ... Sciences on plant and animal domestication edited by ...
(Date:4/17/2014)... NJ. April 16, 2014. Kessler Foundation has been ... million from the Department of Defense Spinal Cord ... principal investigator for the randomized, double-blinded, controlled, multi-site ... bone and muscle strength after spinal cord injury. ... & Engineering Research at Kessler Foundation. Two additional ...
(Date:4/17/2014)... Professor Marc Andr Gauthier and Professor Luca Razzari ... each been awarded large grants from the John ... for Innovation (CFI) for the acquisition of state-of-the-art ... be added matching grants from the Ministre de ... et de la Technologie (MESRST). These new laboratories ...
Breaking Biology News(10 mins):Chickens to chili peppers 2Chickens to chili peppers 3Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2New state-of-the-art biotech and nanotech equipment for INRS 2
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