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ATPase in Medical News

Team learns how cellular protein detects viruses and sparks immune response

... parts: caspase-recruitment domains (CARDs) and an atpase domain that consumes ATP, the cellular fuel molecu... Earlier research had also shown that the central atpase domain is critical to the function of the molecule...is detected. But a big question remained about the atpase domain: It was using ATP to do something but what...
ATPase in Medical Technology

Clinical Update - Debio 0614 (Istaroxime) in Acute Heart Failure

... acute heart failure syndromes with low output stage. It inhibits the Na+K+ atpase pump, also known as the sodium-potassium pump and restores the SERCA2 ATPase activity (Sarcoplasmic Reticulum Calcium atpase 2 activity). The combined mechanism of action allows for cytosolic calcium ...
ATPase in Biological News

Compound that helps rice grow reduces nerve, vascular damage from diabetes

... Dr. Usuki is talking about enzymes such as ATPase, which help maintain nerve membranes so they can conduct electricity and communicate. Decrease of atpase is a hallmark of the nerve damage that accompanies diabetes. Also reduced in diabetes is homocysteine-thiolactonase, or HTase, an enzyme that decrease...

Biophysical Society announces winners of 2008 Student Travel Awards

... Hydrogel Bilayers. Christopher P. Toseland, MRC-National Institute for Medical Research, London, United Kingdom, Helicase Superfamily 1 and 2 atpase Mechanisms. Martijn E. van Raaij, University of Twente, Enschede, The Netherlands, Quantitative Atomic Force Microscopy Establishes Free Energy...

Researchers make headway in mystery of migraines

.... Blostein and her team showed several genotypes damage the operation of a tiny cellular mechanism commonly known as the Sodium Pump (Sodium/Potassium atpase enzyme). "Much of what happens in your brain--from memory to basic movement--is the result of the transmission of electrical impulses along nerve c...
ATPase in Biological Products

Mouse Anti-alpha Sodium Potassium ATPase Monoclonal Antibody, Unconjugated, Clone M7-PB-E9 from Abcam

Description: Mouse monoclonal [M7-PB-E9] to pan alpha Sodium Potassium ATPase ( Abpromise for all tested applications)....
Company:Abcam

Mouse Anti-SERCA 1 ATPase Monoclonal Antibody, Unconjugated, Clone IIH11 from Novus Biologicals

Description: ...
Company:

Mouse Anti-Na+ / K+ ATPase alpha-1 Monoclonal Antibody, Unconjugated, Clone C464.6 from Upstate

Description: Anti-Na + /K + ATPase α-1, clone C464.6 GenBank Accession Number : NM_001001586 Immunogen : Purified Na + /K + ATPase isolated from membrane fractions of rabbit kidney outer medulla Formulation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl containing 0.05% sodium azide Quality Assurance: routine...
Company:Upstate

Mouse Anti-RFC1 Monoclonal Antibody, Unconjugated, 1320 from GeneTex

Description:... during simian virus 40 DNA replication in vitro. It consists of five different subunits known as p140, p40, p38, p37, and p36. RFC is a DNA-dependent atpase that binds in a structure-specific manner to the 3-prime end of a primer hybridized to a template DNA, an activity thought intrinsic to the 140-kD com...
Company:GeneTex

Anti-Heat Shock Protein 75 (hsp75) (TRAP-1) Ab-2 Monoclonal Antibody, Unconjugated from Lab Vision

Description:...mammalian cells consists of Hsp90 alpha and beta, Grp94, and Trap-1 (Hsp75). It was found that human TRAP-1 is localized to mitochondria and exhibited atpase activity that was inhibited by both geldanamycin and radicicol indicating that TRAP-1 has functions that are distinct from those of hsp90. It was also...
Company:Lab Vision
ATPase in Biological Definition

ATPase

ATPases are a class of enzymes that catalyze the decomposition of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and a free phosphate ion . This dephosphorylation reaction releases energy , which the enzyme (in most cases) harnesses to drive other chemical reacti...

Active transport

... that perform this type of transport are transmembrane ATPases . A primary atpase universal to all cellular life is the sodium-potassium pump , which helps ...rmal or resting concentration of this important second messenger . But the atpase exports calcium ions more slowly: only 30 per second versus 2000 per second...

ATP synthase

...able to show that this particle is correlated with atpase activity in uncoupled mitochondria and with the atpase activity in submitochondrial particles created by exposing mitochondria to ultrasound. This atpase activity was further associated with the creation ...

Ion gradient

...s the proton gradient. Transmembrane ATPases or transmembrane proteins with atpase domains are often used for making and utilizing ion gradients. The enzyme Na+/K+ atpase use ATP to make a sodium ion gradient and a potassium ion gradient. P...

Proton pump

...ed cytochrome c . In the plasma membrane proton atpase and in the atpase proton pumps of other cellular membranes, ATP its...ly halobacteria . See also: transmembrane atpase active transport cytochrome mitocho...
ATPase in Biological Dictionary

UvrA

... and UvrB (ttUvrB) proteins. ... uvrA . FUNCTION: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an atpase and a DNA-binding protein. ... In bacteria, the damage recognition step is carried out by two proteins called UvrA and UvrB. ... UvrA belongs...

Sarcoplasmic reticulum

...es of sarcoplasmic reticulum membranes. ... Lipid composition of purified fragmented sarcoplasmic reticulum of the rabbit. ... The purified atpase of sarcoplasmic reticulum exists as particles with minimum ... Sarcoplasmic Reticulum in Duchenne Muscular Dystrophy ... Sarcoplasmic re...

Proton-motive force

...rce carried out by some ... PROTON MOTIVE FORCE (PMF), THE ... TO BE ALIVE?TO LIVE OR NOT TO LIVE PROTON MOTIVE FORCE ... ... the FliI atpase and proton motive force in bacterial flagellar protein ... posted to flagella proton - motive - force secretion by biomcgary on 2008-01-23 2...

Myofibrils

...emically skinned rabbit heart and mounted ... Myofibrils were prepared as described (24) with careful attention paid to the ... We measured the atpase activity of myofibrils extracted from non-TG control and ... The arrangement of myofibrils within a fiber is such that a perfectly aligned ... ...

MutS

...ein initiates mismatch repair with recognition of a non-Watson-Crick ... Integration of these MutS DNA-binding kinetics with previously described atpase ... The MutS Δ800 protein binds to O6-methylguanine mismatches but not to intrastrand ... Mutations in genes that incapacitate MMR ( mutS , mutL...

Helicase

... of pharmacological agents useful for the ... Runyon et al., Eischerichia coli helicase II (UvrD) protein initiates DNA ... The helicase and atpase activities residing in the SCFhFBH1 complex were ... This result suggested that S.pombe DNA helicase I may play a role in DNA ... The helicase ...

Dynein

...ain, we ... Dynein motors transport activated Trks to promote survival of target-dependent neurons. ... stalk coiled coil of dynein couples atpase and microtubule binding. ... myosin and kinesin, in dynein the microtubule-binding domain ... dynein motor unit is constructed around a serie...

Chaperone protein

... " chaperone " protein known as UNC-45, according to ... Copper chaperone proteins have consequently evolved as part of a complex network ... atpase to have the same CXXC Cu-binding motif as the chaperone protein (Figure 2) ... "Pilus biogenesis via the chaperone /usher pathway: an int...
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