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Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...

A much-needed shot in the arm for HIV vaccine development

International efforts towards developing avaccine against HIV infection have been given a much-needed boost bythe publication today of the Global HIV/AIDS Vaccine Enterprise'sscientific strategic plan, published online in the freely available,open-access global health journal PLoS Medicine.The Global HIV/AIDS Vaccine Enterprise is an international alliance ofindependent agencies and organiz...

Researchers reveal the infectious impact of salmon farms on wild salmon

A new study published in the March 30th edition of the prestigious scientific journal Proceedings of the Royal Society B (a publication of the UK's national academy of science) shows that the transfer of parasitic sea lice from salmon farms to wild salmon populations is much larger and more extensive than previously believed. This quantitative analysis of parasite transfer is a scientific...

Octopuses occasionally stroll around on two arms, UC Berkeley biologists report

In a stunning example of evolution at work, scientists have now found that changes in a single gene can produce major changes in the skeletal armor of fish living in the wild. "Our motivation is to try to understa...

Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined

Glia appear essential for 'hair cells'responsible for hearing and balance. Traditionally viewed as supportingactors, cells known as glia may be essential for the normal developmentof nerve cells responsible for hearing and balance, according to newUniversity of Utah research. The study is reported in the January 6,2005 issue of Neuron and is co-authored by scientists at the Universityof Was...

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Corning Proculture Spinner Flask,15L,Vertical S/Arm, No. Of S/A 4,Cent Neck 100mm from Sigma-Aldrich

Description:This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,487-9) or contact customer service for assistance. ID clarifier: centre neck 100 mm, No. of sidearm 4 Mfr Desig: Corning 4510-15L...
Company:Sigma-Aldrich

AAIBiotech Solutions from AAIPharma Inc.

Description:AAIPharmas Biotech Solutions Group combines deep experience, skills and flexibility in product development with special qualities of collaborative team chemistry. This combination enables optimum solutions and strategy from concept to approval and beyond.With AAIBiotech, you can count on our excellent scientific capabilities. But you get more than that: its the power of team chemistry that...
Company:AAIPharma Inc.

Functional Genomics & Pharmacogenomics from Dominion Pharmakine S.L.

Description:Gene expression profiling allows a high-throuput screening of a biological systems phenotype, so that naturally occuring or artifitially induced changes in the expression levels of the genes in that system can be detected, studied, classified and compared to each other, covering a broad range of genes at a glance. Automatized scanning of the hybridized slides in Agilent Technologies G2565 Microar...
Company:Dominion Pharmakine S.L.

Routine Testing Laboratory from AAIPharma Inc.

Description:AAIPharmas Routine Testing Laboratory (RTL) can provide you with the expertise developed over 25 years. Microbial method development and validation Performance of methods used to monitor the conditions of your GMP manufacturing environment Assurance of quality for manufactured productsWe offer a full spectrum of microbiological services to the pharmaceutical industry. O...
Company:AAIPharma Inc.

Functional Proteomics & Pharmacoproteomics from Dominion Pharmakine S.L.

Description:The proteomic service includes protein separation by two-dimensional electrophoresis (2D-PAGE), image analysis using the PDQuest software package from Bio-Rad and protein identification by MALDI-TOF mass spectrometry. In order to meet customers requirements regarding experimental design, sample preparation, data analysis and format of the results permanent contact with our Functional Proteomic Un...
Company:Dominion Pharmakine S.L.

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arm at Biology Technology

Analyzing Trace-Level Impurities of a Pharmaceutical Intermediate Using an LCQ Deca Ion Trap Mass Spectrometer and the Mass Frontier Software Package

Mark R. Kagan , Carrie Liu 1Thermo Finnigan, Piscataway, NJ; 2Thermo Finnigan, San Jose, CA; 3Eisai Research Institute, Andover, MA The data presented here can be a...

Lance Armstrong and the future of cancer care

As many people know, survivors of cancer are much more common today. A recent National Center for Health Sta...

Third Wave receives FDA clearance of pharmacogenetic test

It is the first pharmacogenetic test to be approved by the FDA for use as a companion diagnostic to a specific drug therapy. The test is c...

High-Tech Solution for Farmers

Good old fashioned problem-solving is alive in Wisconsin today. Five years ago Chad Sorenson was talking with his cousin in Iowa, a farmer who grows corn. The cousin complained about the tedious task of applying anhydrous ammonia, a fertilizer, and specifically how he had to stop his tractor and walk 40 feet behind him to determine how much fertilizer was left in the tank. The seed was planted.<b...

Rapid SNP Genotyping of the Pharmacogenomically Important Allele CYP2D6*4 Using Real-Time qPCR on the DNA Engine Opticon 2 System

MJ Research, Inc., South San Francisco, CA A two-color real-time quantitative PCR (qPCR) protocol was used on the MJ Research DNA Engine Opticon 2 system to genotype the CYP2D6*4 allele in 211patient samples. Two hydrolysis probes, one labe...

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arm at Medicine News

NEW ROBOTIC SURGERY ARM APPROVED BY FDA

FDA today cleared for marketing a robotic device that enables a surgeon to perform laparoscopic gall bladder and reflux disease surgery while seated at a console with a computer and video monitor. The surgeon can use hand grips and foot pedals on the console to control three robotic arms that can perform the surgery using a variety of surgical tools. The product, the Da Vinci Surgical Sys...

India to benefit from pharma companies' move

The decision by 39 pharmaceutical companies to drop a historic case in South Africa has far-reaching consequences for India and other developing countries, according to leading non-governmental organizations (NGOs). The 39 companies had challenged a South African government order that legalized use and import of generic medicines free from patents. The pharmaceutical companies, which inc...

No harm in reducing prenatal check up to 3 - 6 times says WHO report

A world health organisation report says that women with low risk pregnancies, who live in the developing nations, can safely cut down their vists to the doctor during pregnancy to 3 - 6 times during pregnancy instead of the prescribed 8 - 11 visits as in the developed nations. However, these women are not more at risk than women who had more prenatal visits to have a low birth weight bab...

South Africa Wins landmark case against pharmaceutical giants

South Africa has scored a landmark legal victory over pharmaceutical giants wanting to stop South Africa from importing cheap AIDS drugs. The country with largest number of AIDS patients in the world now wants to secure affordable drugs from around the world to tackle its AIDS epidemic. The Health Ministry of South Africa, published 70 pages of draft legislation that would allow it to s...

Pharmaceutical giant offers AIDS related antifungal drug free to 50 countries

Diflucan Partnership seems to be the latest mantra of Pfizer. The pharmaceutical giant has announced that it will supply free antifungal drug to 50 countries hardest hit by the AIDS virus. The decision by the Pfizer comes close on the heels of the South African Government winning a landmark case against pharmaceutical companies. In an announcement on Wednesday Pfizer said AIDS related a...

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Stellate Harmonie E

Description:The Stellate Harmonie workstation is a medical device designed to handle the intense processing loads, high quality video capability, and archiving demands of the EEG laboratory. Advanced recording and review functions A framework that helps organize workflow and the collection, evaluation and archiving of data A centralized database and powerful search capability keeps track of every patient ent...
Company:Stellate Systems Inc.

Stellate Harmonie S

Description:State-of-the-art sleep recording and analysis...
Company:Stellate Systems Inc.

PCL Guide Arm

Description:Part of the GraFix® Cruciate Reconstruction System, which is designed to facilitate arthroscopic anterior cruciate ligament reconstructions....
Company:Linvatec Corporation (now ConMed)

Harms Corneal Utility Forceps, Colibri Style

Description:0.12 mm, 1 x 2 teeth set at 45 degrees with 4.5 mm tying platform. Serrated handle with polished finish....
Company:Bausch & Lomb Storz

Bishop-Harmon Dressing Forceps

Description:Straight crisscross serrated tips. Flat handle with holes and polished finish....
Company:Bausch & Lomb Storz

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arm at Medicine Technology

Sygnis Pharma AG announces date for presentation of clinical results

HEIDELBERG, Germany, 11 July 2007 – On 23 July SYGNIS PharmaAG will present the results of the clinical phase IIa study forAX200 (AXIS-study). AX200, a compound for the treatment of stroke, is the mostadvanced drug candidate in SYGNIS’ product pipeline. Theprimary aim of the study is to show safety and tolerability ofAX200 in acute stroke patients. The results of the AXIS-stud...

Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting

GENEVA, July 11, 2007 /PRNewswire/ -- InspirationBiopharmaceuticals today announced the presentation of preclinicaldata supporting the development of new, proprietary forms ofrecombinant Factor IX to treat patients with Hemophilia B. The datawere highlighted in an oral presentation and a poster session atthe XXIst Congress of the International Society on Thrombosis andHaemostasis (ISTH)...

BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine

LINCOLNSHIRE, Ill.--(BUSINESS WIRE)--Jul 11, 2007 - BioSantePharmaceuticals, Inc. (Amex: BPA) today announced new positiveresults demonstrating that its calcium phosphate (CaP)nanoparticle-based vaccine adjuvant, BioVant(TM), may serve as aneffective vaccine adjuvant for the development of a dose sparingvaccine against H5N1 avian flu, widely known as bird flu. The new results are based on...

Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis

SAN FRANCISCO, July 10, 2007 /PRNewswire/ -- PortolaPharmaceuticals, Inc. announced positive Phase II data on its leadcompound, PRT054021, an oral Factor Xa inhibitor, today at the XXICongress of the International Society on Thrombosis and Haemostasis(ISTH) in Geneva, Switzerland. The EXPERT trial showed thatPRT054021 was safe, effective, and well tolerated for theprevention of venous th...

Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone

- Results Fail to Demonstrate Meaningful Placebo Adjusted WeightLoss; Obesity Program to be Discontinued NEW YORK, July 09, 2007 /PRNewswire-FirstCall/ -- ManhattanPharmaceuticals, Inc. today announced results of the company's twoPhase 2a clinical trials of oral Oleoyl-estrone (OE). The resultsof both randomized, double-blind, placebo-controlled studies, onein common obesity and the other...

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