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ADMET in Medical News

Genetic Engineering and Biotechnology News reports on early ADMET use

NEW ROCHELLE, NY, May 5, 2008Biotech and pharma companies are increasingly utilizing novel technologies to assess the druggability of test compounds early in the development cycle to avoid costly late clinical-stage attrition, according to Genetic Engineering and Biotechnology News (GEN) ( http://...
ADMET in Medical Technology

Ono Enters into a New Fragment-Based Drug Discovery Agreement with Evotec

...eening in combination with its high-quality fragment libraries. In the collaboration it is combined with Evotec's expertise in medicinal chemistry and admet to further characterize active compounds identified and optimize their potency and selectivity to generate molecules for subsequent progression into c...

AEterna Zentaris Discloses First In Vitro Data for its PI3K Inhibitors at the AACR Annual Meeting in Los Angeles

...geting the inhibition of PI3K and functional cellular assays of tumor cell proliferation have been performed. In addition, physicochemical and initial admet data were collected. Several derivatives are currently undergoing first pharmacokinetic in vivo studies. About AEterna Zentaris Inc. AEterna Zenta...

terna Zentaris Discloses First In Vitro Data for its PI3K Inhibitors at the AACR Annual Meeting in Los Angeles

...ng the inhibition of PI3K and functional cellular assays of tumor cell proliferation have been performed. In addition, physicochemical and initial admet data were collected. Several derivatives are currently undergoing first pharmacokinetic in vivo studies. About terna Zentaris Inc. ...
ADMET in Biological Technology

Genetic Engineering and Biotechnology News (GEN) Reports on Early ADMET Use

NEW ROCHELLE, N.Y., May 5 /PRNewswire/ -- Biotech and pharma companies are increasingly utilizing novel technologies to assess the druggability of test compounds early in the development cycle to avoid costly late clinical-stage attrition, according to Genetic Engineering and Biotechnology New...

Palkion Selects Novel Oral Development Candidate for the Treatment of Anemia

...d proprietary platform technologies for structural biology, structure-based novel scaffold/lead design, lead optimization and candidate selection with admet capability. CrystalGenomics is headquartered in Seoul, Korea and its subsidiary, CG Pharmaceuticals Inc. is located in Emeryville, CA for US and EU cl...

Celsis Outlines the Top Five Advantages of Cryo-plateable Hepatocytes

... to results , enabling more productive and cost-effective research. Celsis IVT's cryo-plateable hepatocytes (the world's largest inventory) and other admet research tools are available worldwide. Visit www.celsis.com/ivt for more information. About Celsis International plc Celsis Internationa...

AEterna Zentaris Presents Two Posters on its PI3K Inhibitor Compound, AEZS-126, at AACR Annual Meeting

... G. Mueller and E. Guenther, the poster focuses on admet and safety profiling of the compound, as well as i...emonstrated favorable properties in early in vitro admet screening including microsomal stability, plasma s...regarding kinase selectivity, cellular potency and admet properties, led to the identification of AEZS-126,...

AEterna Zentaris To Present Data on Anticancer Compounds AEZS-112 and AEZS-126 at AACR Annual Meeting

...r effects", I. Seipelt, S. Baasner, M. Gerlach, M. Teifel, J. Fensterle, L. Blumenstein, G. Mueller and E. Guenther, the poster focuses on admet and safety profiling of the compound, as well as in vivo pharmacokinetic experiments and mouse xenograft antitumor studies. AEZS-126 (Poste...

Evotec Expands Collaboration With InterMune

...ry know-how. In addition, they will utilize their expertise and technologies in computational chemistry, protein production, X-Ray crystallography and admet to further characterize active compounds and optimize their potency and selectivity to generate lead molecules for subsequent progression into clinica...

BioReliance Launches Next-Generation Genotoxicity Screening Service

...evelopment. Gentronix's first product release, GreenScreen, successfully combines expertise in molecular biology and analytical science to address the admet bottleneck in lead candidate selection, focusing specifically on genotoxicity screening. GreenScreen products are for use in genetic toxicity screenin...
ADMET in Biological Products

LabCD ADMET System from Tecan

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