Genetic Engineering and Biotechnology News (GEN) Reports on Early ADMET Use
NEW ROCHELLE, N.Y., May 5 /PRNewswire/ -- Biotech and pharma companies
are increasingly utilizing novel technologies to assess the druggability of
test compounds early in the development cycle to avoid costly late
clinical-stage attrition, according to Genetic Engineering and
Palkion Selects Novel Oral Development Candidate for the Treatment of Anemia
...d proprietary platform technologies for structural biology, structure-based novel scaffold/lead design, lead optimization and candidate selection with admet
capability. CrystalGenomics is headquartered in Seoul, Korea and its subsidiary, CG Pharmaceuticals Inc. is located in Emeryville, CA for US and EU cl...
Celsis Outlines the Top Five Advantages of Cryo-plateable Hepatocytes
... to results , enabling more productive and cost-effective research. Celsis IVT's cryo-plateable hepatocytes (the world's largest inventory) and other admet
research tools are available worldwide. Visit www.celsis.com/ivt for more information.
About Celsis International plc
AEterna Zentaris Presents Two Posters on its PI3K Inhibitor Compound, AEZS-126, at AACR Annual Meeting
... G. Mueller and E. Guenther, the poster focuses on admet
and safety profiling of the compound, as well as i...emonstrated favorable properties in early in vitro admet
screening including microsomal stability, plasma s...regarding kinase selectivity, cellular potency and admet
properties, led to the identification of AEZS-126,...
AEterna Zentaris To Present Data on Anticancer Compounds AEZS-112 and AEZS-126 at AACR Annual Meeting
...r effects", I. Seipelt, S. Baasner, M. Gerlach, M. Teifel, J.
Fensterle, L. Blumenstein, G. Mueller and E. Guenther, the poster
focuses on admet
and safety profiling of the compound, as well as in
vivo pharmacokinetic experiments and mouse xenograft antitumor studies.
Evotec Expands Collaboration With InterMune
...ry know-how. In addition, they will utilize their expertise and
technologies in computational chemistry, protein production, X-Ray
crystallography and admet
to further characterize active compounds and
optimize their potency and selectivity to generate lead molecules for
subsequent progression into clinica...
BioReliance Launches Next-Generation Genotoxicity Screening Service
...evelopment. Gentronix's first product release,
GreenScreen, successfully combines expertise in molecular biology and
analytical science to address the admet
bottleneck in lead candidate
selection, focusing specifically on genotoxicity screening. GreenScreen
products are for use in genetic toxicity screenin...