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ADAMTS13 in Medical News

Researchers Detect Blood-Clotting Mechanism

...d that the tiniest force causes A2 molecules to unfold and lose much of their complex, three-dimensional organization. After the unfolding, the enzyme adamts13 comes into play. The enzyme cuts the molecule, hence controlling the size of the blood clot, according to the study, in the June 5 issue of Science ....
ADAMTS13 in Medical Technology

Vermillion and the Ohio State University Report That Novel Diagnostic Test May Help Predict Risk for Relapse of TTP, A Serious Blood Disorder

...." The study showed that extremely low levels of adamts13 activity are associated with increased risk of TTP...d exhibits improved accuracy at low (<2.5 percent) adamts13 activity. "These study findings represent an imp... relapse in patients with TTP. About the Study adamts13 activity and...
ADAMTS13 in Biological Technology

Baxter Adds Recombinant Protein to Specialty Therapeutics Portfolio

...peutics targeting rare diseases. In the absence of adamts13 in the blood, patients develop a severe, often lif... in blood vessels throughout the body. Recombinant adamts13 is being developed for the treatment of TTP and re...al needs. "We are very excited to add recombinant adamts13 to our development pipeline," said Hartmut J. Ehrl...
ADAMTS13 in other areas

ADAMTS13 - Wikipedia, the free encyclopedia

ADAMTS13 —also known as von Willebrand factor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood...

ADAMTS13 - ADAM metallopeptidase with thrombospondin type 1 motif, 13 ...

Thrombotic thrombocytopenic purpura is a rare disorder of the blood-coagulation system, causing extensive microscopic thromboses to form in small blood vessels throughout the body . Most cases of TTP arise from inhibition of the enzyme ADAMTS13, a metalloprotease...

ADAMTS13

Malfunctioning of ADAMTS13 results in accumulation of ULvWF multimers in plasma ... Thrombotic Thrombocytopenic Purpura (TTP) and ADAMTS13 ...

ADAMTS13 antibody (ab72335) | Abcam

Goat polyclonal to ADAMTS13. ... Rabbit polyclonal to ADAMTS13 - Carboxyterminal end long isoform (ab28273) ... ADAMTS13, also known as von Willebrands factor ...

ADAMTS13 antibody [A10] (ab51401) | Abcam

ADAMTS13, also known as von Willebrands factor cleaving protease (vWFcp), was ... Rabbit polyclonal to ADAMTS13 - Carboxyterminal end long isoform (ab28273) ...

ADAMTS13

ADAMTS13 is an enzyme of the family identified as "a disintegrin and ... The ADAMTS13 assay may be used to distinguish chronic recurring thrombotic ...
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