Brain Tumor Drug May Help Spur Cancer's Return
...he ability to renew themselves and resist chemotherapy, the team found, and abcg2
appears to be a marker for these resistant cells.
Holland's group also ... may render surviving cells more resistant to treatments that do target the abcg2
protein, Holland theorized.
"Life is complicated; brain tumors are compl...
Brain tumor treatment may increase number of cancer stem-like cells
...e almost complete abolition of this phenotype when abcg2
activity is blocked, we subsequently studied the o...stant to chemotherapy. These results verified that abcg2
activity, although not by itself oncogenic, is a m...molecular mechanism that modulates the activity of abcg2
and enhances the ability of cancer stem-like cells...
ABCG2 - Wikipedia, the free encyclopedia
ATP-binding cassette, sub-family G (WHITE), member 2, also known as ABCG2
, is a human gene. ABCG2
has also been designated as CDw338 .
SNP linked to Gene ABCG2(geneID:9429) Via Contig Annotation
Database of Single Nucleotide Polymorphism ... SNP linked to Gene ABCG2
(geneID:9429) Via Contig Annotation. rs# on all gene models to Batch Query ...
Modulation of function of three ABC drug transporters, P-glycoprotein ...
... protein (MXR or ABCG2
) and multidrug resistance protein ... ABCG2
protein, human. ATP-Binding Cassette Transporters. Antineoplastic Agents. Fluoresceins ...
Abcg2 Rat Gene (ATP-binding cassette, sub-family G (WHITE), member 2 ...Abcg2
(ATP-binding cassette, sub-family G (WHITE), member 2) transporter involved in brain-to-blood efflux transport ... Homo sapiens: ABCG2
See the Human gene ...
urate Articles in Rheumatology
urate Rheumatology news articles are served up daily at MDlinx.com. ... Native ABCG2
is located in the brush border ... renal urate secretion ...
Effects of sex hormones on regulation of ABCG2 expression in the ...
The expression level of ABCG2
protein was analyzed by Western blot analysis. ... It is known that ABCG2
transports a variety of substrates, including anticancer ...