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ABCA1 in Medical News

JCI table of contents: Nov. 8, 2007

...IOVASCULAR DISEASE: Two heads are better than one: abca1 and ABCG1 combine to enable HDL to protect us from...as macrophage foam cells via two proteins known as abca1 and ABCG1. Previous studies examining the role of ...c effects of HDL. In this study, mice lacking both abca1 and ABCG1 were generated. When bone marrow from th...

Cholesterol mystery solved through research mice

...address these questions." These specially developed mice have mutations in a gene (ABCA1) involved in HDL production. In one group of animals, the abca1 gene is selectively deleted in the liver – which means their livers cannot produce HDL. It was through studying these mice that the scientists were ab...
ABCA1 in Biological News

Dominant cholesterol-metabolism ideas challenged by new research

...n the on-line journal PLoS One. A protein called abca1 is critical for producing "good" cholesterol: pat...s at an early age. An important question is what abca1 does that is so important for producing HDL. T...uild-up of PS on the cell surface. Alternatively, abca1 might activate or might actually be the enzyme, s...
ABCA1 in Biological Technology

RVX-208 Data Demonstrates Increase in Functional HDL Particles

...orresponding prebeta-HDL change was 42% (P=0.007) in the actively treated group compared to control. Furthermore, sera from subjects were assessed for abca1 mediated cholesterol efflux as a predictive marker for reverse cholesterol transport. Again, ABCA1-dependent cholesterol efflux change increased by 10...
ABCA1 in Biological Products

Rat Anti-Mouse ABCA1 Monoclonal Antibody, Unconjugated, Clone 5A1-1422.11 from ABR-Affinity BioReagents

Description: ABCA1 Immunogen: Mouse ABCA1-expressing HeLa stable transfectants. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Company:ABR-Affinity BioReagents
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