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Novel Small Molecule Therapy Shows Benefit for Anemic Patients Via Hydration of Red Blood Cells

WASHINGTON, Feb. 5 /PRNewswire-USNewswire/ -- Researchers are identifying innovative therapeutics for sickle cell anemia that focus on specific factors in the disease's progression, such as the important role of hydration of the red blood cells. According to a study prepublished online in Bloo...

Scientists Discover Origin of Malaria

... humanity. Chimpanzees, native to equatorial Africa, have been identified as the original source of the parasite that likely moved from them to humans via mosquitoes. An international group of researchers, including senior author Nathan Wolfe, Ph.D., of the Global Viral Forecasting Initiative and ...

Project Zero Delay Accelerates Drug's Path to Clinical Trial

...nked No. 1 in cancer care in "America's Best Hospitals," a survey published annually in U.S. News & World Report. Get M. D. Anderson News via RSS Follow M. D. Anderson News on Twitter About AstraZeneca AstraZeneca is a major international healthcare business engage...

World's First Cardiac Adult Stem Cell Patient Receives Infusion

...diactrial@louisville.edu . Video of a news briefing along with b-roll with the physicians and the patient will be uplinked today, July 24, via satellite from 12-1 p.m. (EDT) at the following coordinates: C-band AMC 6 Transponder 21 Uplink Frequency 6345 Horizontal Downlink Fr...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... (cloning) or embryonic stem cells and allows rapid creation of new animal models." In the study published in Science titled "Knockout Rats via Embryo Microinjection of Zinc Finger Nucleases," (Geurts, et al.) scientists used ZFNs to knock out an inserted reporter gene and two native rat genes...

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

...EX((R) )(mometasone furoate inhalation powder), with the long-acting beta2-agonist, FORADIL((R)) (formoterol fumarate inhalation powder), administered via a single metered-dose inhaler. Schering-Plough has exclusive worldwide rights for the development and commercialization of the mometasone furoate and ...

July 2009 Mayo Clinic Health Letter Highlights a Positive Outlook, Bell's Palsy and Heart Valve Repair

... been addressed -- with good success and safety -- via open heart surgery. During surgery, the chest is o...hey include: Artificial valve placement via catheter: A collapsible artificial heart valve su...ed by an expanding wire mesh (stent) can be placed via small incisions without stopping the heart. The de...

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

... please visit the Company's web site at www.hgsi.com . Health professionals and patients interested in clinical trials of HGS products may inquire via e-mail to clinical_trials@hgsi.com " target="_new"> clinical_trials@hgsi.com or by calling HGS at (301) 610-5790, extension 3550. HGS, Human Ge...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

...gan have shown that as many as 15% of women in the study group determined to be negative for the presence of human papillomavirus (HPV) in the cervix, via the most commonly used test for HPV DNA, may actually be infected with the virus at clinically relevant viral loads. PCR-MS detected the presence of h...

Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)

...d predominantly by urologists using surgical resection and intravesical infusion therapy. Urocidin is an intravesical infusion therapy, administered via trans-urethral catheter into the bladder. The first of two Phase III U.S. Food and Drug Administration (FDA)-approved and Fast Track designated...

Iontophoretic Drug Delivery System (IDDS) Containing Lidocaine and Epinephrine is Effective in Reducing Pain Associated With Insertion of an Intravenous Catheter in a Phase 2 Clinical Trial

...ore Exchange Limited) announced that its improved active transdermal delivery technology, which administers lidocaine and epinephrine through the skin via a mild electric current, has demonstrated safety and efficacy in a Phase 2 clinical trial. About the Trial: The trial conducted was a Phase ...

FDA Accepts sNDA for Alternative Dosing Regimen for Dacogen(R) (decitabine for injection) to Treat Patients with Myelodysplastic Syndromes (MDS)

...limit the production of functional blood cells. Currently, Dacogen is approved for use as a three-day regimen, administered at a dose of 15 mg/m2 via continuous IV infusion over three hours repeated every eight hours for three consecutive days per cycle. The cycle is repeated every six weeks. The a...

Shire has Filed a Treatment Protocol for Velaglucerase Alfa for Gaucher Disease

...ith the FDA to file a New Drug Application (NDA) for velaglucerase alfa as early as possible. Shire will provide further updates when available via press releases and/or its website ( http://www.shire.com ) on its progress with its discussions with the FDA and other regulatory bodies about the dev...

PARI LC Plus and PRONEB Ultra Used in Two Perforomist Studies on Improving COPD Therapies

...oterol fumarate to ipratropium/albuterol delivered via a metered dose inhaler. The study concluded that ...han treatment with ipratropium/albuterol delivered via MDI. The Tashkin et al. study, presented at ...of adding nebulized formoterol fumarate, delivered via PARI's LC Plus and PRONEB Ultra, to maintenance ti...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

...cused in specific areas of the brain, but may become more generalised; the symptoms vary according to the affected areas. Nerve impulses are triggered via voltage-gated sodium channels in the nerve cell membrane. Treatment of partial-onset seizures, the most common type of epilepsy, presents a con...

SUNY Youth Sports Institute Convenes Top Experts in NYC Next Week to Present Research & Analysis on Energy Drink Health Impacts

...30PM at the SUNY Fashion Institute of Technology, The John Reeves Great Hall, 7th Avenue & 28th Street, New York, NY. Pre-registration is required via http://www.conference.youthsportsny.org The SUNY Youth Sports Institute will package evidence-based findings into one easy-to-understand, ...

Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)

...hly efficient aerosolization of medication including liposomal formulations via a vibrating, perforated membrane that includes thousands of laser drilled h...s. The company's major focus is on developing antibiotic therapy delivered via proprietary advanced pulmonary liposome technology in areas of high unmet...

Hand Washing with 4% CHG Antiseptic Kills Flu Viruses

... of virus is the biggest concern," said Carolyn Twomey, RN, Global Head of Clinical Services, Molnlycke Health Care. "Influenza viruses usually spread via sneezing and coughing and contaminating one's hand or hands, and then touching surfaces, shaking hands or other contact behaviors. With any influenza...

CoAxia, Inc. Announces $21.5M Series D Financing

...ition to the SENTIS, Flo24 and FASTFlo trials for ischemic stroke, CoAxia's NeuroFlo(TM) & FloControl(TM) devices have been approved by the US FDA via Humanitarian Device Exemption for the treatment of cerebral vasospasm, have received US FDA 510(k) clearance, and have secured the CE Mark for cerebra...

Alfacell Provides Shareholder Update

...s whether Onconase can be used as routine tool to detect the gene silencing via RNA interference (RNAi) mechanism. Currently, there are thousands of resea...ring normal cells. ONCONASE triggers apoptosis, the natural death of cells, via multiple molecular mechanisms of action. About Alfacell Corporation ...

New Safety Regulations Drive Greater Need for Resources and Expertise at Every Stage of Clinical Development

...ed global trends in drug safety issues, and to evaluate the impact of recent safety regulations on the industry. A total of 140 people were questioned via a telephone interview, and included the heads of pharmacovigilance, safety and clinical research functions among pharmaceutical and biotechnology comp...

Neurocrine Biosciences Presents Elagolix Data

...ther neurological and endocrine related diseases and disorders. Neurocrine Biosciences, Inc. news releases are available through the Company's website via the internet at http://www.neurocrine.com . In addition to historical facts, this press release may contain forward-looking statements that...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

...gs also underline the key role played by the immunoproteasome in development of the inflammatory process. "Targeting protein degradation pathways via the proteasome represents a completely novel approach to regulating the immune response. Using a specially designed proprietary assay, our team of re...

New Studies Presented at European Society of Anaesthesia Further Validate Masimo PVI(TM) for Noninvasive and Continuous Fluid Monitoring

...u University School of Medicine in Hamamatsu-City, Japan, compared the accuracy of Masimo PVI measurements with Stroke Volume Variation (SVV) obtained via an invasive catheter (Flo Trac(R)) in 13 patients. After analyzing data recorded at five points--in the supine position, lateral position, start and ...

VIA Pharmaceuticals Meets With FDA to Discuss Next Steps For VIA-2291 and Phase 3 Outcome Trial in Cardiovascular Disease

... SAN FRANCISCO, June 11 /PRNewswire-FirstCall/ -- via Pharmaceuticals, Inc. (Nasdaq: VIAP ), a biotech...ry Cohen, President and Chief Executive Officer of via Pharmaceuticals, Inc. "VIA-2291 specifically targe...hese major adverse cardiac events." About via Pharmaceuticals, Inc. ...

Oramed Pharmaceuticals to Present at the 8th National Life Science & Technology Week ILSI -BIOMED Conference, Israel 2009

...armaceuticals Oramed Pharmaceuticals is a technology pioneer in the field of oral delivery solutions for drugs and vaccines presently delivered via injection. Oramed is seeking to revolutionize the treatment of diabetes through its patented flagship product, an orally ingestible insulin capsule cu...

DOR BioPharma Receives EMEA Agreement on the Design of its Confirmatory Phase 3 Clinical Trial of orBec(R) in GI GVHD

...R and the FDA reached agreement on the design of the upcoming Phase 3 study via the Special Protocol Assessment (SPA) procedure. An agreement via the SPA procedure is an agreement with the FDA that a Phase 3 clinical tria...

VivoMetrics(R) Introduces Next Generation LifeShirt Prototype, a Smart Garment That Delivers Real-time Vital Signs Remotely to Healthcare Providers

...ntext with posture and activity levels and automatically transmit that data via cellular networks or Bluetooth to their healthcare providers. VivoMetr...ward-looking statements in the future. (1) Litan, Robert, Vital Signs via Broadband Health Monitoring Transmits Savings, Enhances Lives , October 200...

Enrollment in Delcath's Pivotal Phase III Metastatic Melanoma Clinical Trial Achieves Seventy-Five Percent Accrual

...treatments. Patients in the Phase III trial initially are randomized into one of two treatment arms, including immediate treatment with melphalan via the Delcath System or treatment with best alternative care. The study is designed to evaluate the duration of tumor response in each of the two study ...

Peregrine Pharmaceuticals Highlights Promising Early Data From Its Three Phase II Bavituximab Cancer Trials

... and dampen the body's normal response to cancer. By binding to and blocking PS, bavituximab is believed to boost the body's ability to combat cancer via this second immunostimulatory mechanism. Further information on the role of exposed PS in the tumor environment can be found in the Anti-PS Technica...

Pharmasset to Present at Goldman Sachs and Needham Healthcare Conferences

...t 3:10 PM (ET) and at the Needham Conference on Thursday June 11, 2009 at 1:00 PM (ET). To access a simultaneous webcast of Mr. Price's overview via the internet, log on to the "Events & Presentations" section of the Investor Center on Pharmasset's website at http://investor.pharmasset.com/e...

PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans

... Food and Drug Administration for L-CsA, delivered via an Investigational eFlow Nebulizer System, for the...ritating solvents and optimized for administration via an Investigational eFlow Nebulizer System without ...mulation of 10mg CsA/2.5mL for inhalation delivery via a customized Investigational eFlow Nebulizer Syste...

Horizon Therapeutics' HZT-501 Significantly Reduces Incidence of NSAID-Induced Upper Gastrointestinal Ulcers in Patients With Mild-to-Moderate Pain

...uodenal ulcers during the 24-week treatment period, as compared to ibuprofen, in patients at risk for NSAID-induced ulcers. The trials were conducted via a Special Protocol Assessment (SPA) with the U.S. Food and Drug Administration (FDA). About HZT-501 HZT-501 is a novel, proprietary fixed-dos...

Trubion Announces Positive Data From a Phase 1 / 2 Study of TRU-016 for the Treatment of Chronic Lymphocytic Leukemia (CLL)

...RU-016 is additive or synergistic in combination with established therapeutics (Abstract 8571) and that TRU-016-mediated apoptosis in CLL cells occurs via a distinct mechanism of apoptosis compared with many other therapeutic agents utilized for the treatment of CLL (Abstract 3035). Copies of all three p...

Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting

...elivered in a single dose directly to the heart muscle during a short outpatient procedure, performed in a standard cardiac catheterization laboratory via a small incision in the upper leg. Of the twelve patients treated, two with low levels of pre-existing antibodies to the AAV vector did not show ...

Stand Up To Cancer Awards $73.6 Million for Novel, Groundbreaking Cancer Research

...book application enables users to share their personal connections to cancer. The online community provides ample opportunity to share SU2C's efforts via a variety of social media outlets, including Twitter, Facebook, AOL, MySpace, YouTube, flickr and several other sites that are accessible through the ...

Lennox International to Present at J.P. Morgan Conference

...n be accessed on the company's website at http://www.lennoxinternational.com and will be archived for 60 days. The webcast can also be accessed via http://metameetings.com/webcasts/jpmorgan/HVAC09 . (Logo: http://www.newscom.com/cgi-bin/prnh/20020304/DAM053LOGO ) Through its subsi...

Boston Scientific Welcomes Results of Brain Aneurysm Clinical Trial

... coiling for the treatment of brain aneurysms." Endovascular coiling is a minimally invasive procedure in which tiny, platinum coils are inserted via catheter through the blood vessels into the aneurysm to prevent further bleeding into the brain. Surgical clipping is an open intervention involving ...

FDA Approves ADCIRCA(TM) (Tadalafil) Tablets for the Treatment of Pulmonary Arterial Hypertension

...112, with international callers dialing 719-457-0820, and using passcode: 2104929. This teleconference is also being webcast and can be accessed via United Therapeutics' website at http://ir.unither.com/events.cfm . About ADCIRCA ADCIRCA is a prescription medicine used to treat PAH, a...

Human Genome Sciences Submits Biologics License Application to FDA for ABthrax(TM)

... please visit the Company's web site at www.hgsi.com . Health professionals and patients interested in clinical trials of HGS products may inquire via e-mail to clinical_trials@hgsi.com " target="_new"> clinical_trials@hgsi.com or by calling HGS at (301) 610-5790, extension 3550. HGS, Huma...
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Breaking Biology News(10 mins):A new synthetic amino acid for an emerging class of drugs 2A new synthetic amino acid for an emerging class of drugs 3Memory and Alzheimer's: Towards a better comprehension of the dynamic mechanisms 2CCNY team defines new biodiversity metric 2
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