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Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

PALO ALTO, Calif., June 15 /PRNewswire-FirstCall/ -- Jazz Pharmaceuticals' (Nasdaq: JAZZ ) sodium oxybate (JZP-6) demonstrated statistically significant and clinically meaningful improvement in pain and the core symptoms associated with fibromyalgia, according to Phase III data presented last we...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

VIENNA, Va., June 5 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (NYSE AMEX: CVM ) announced today that its collaborators at the University of Hawaii reported on data at the annual American Society for Microbiology in Philadelphia, PA. This data demonstrates that vaccines utilizing its L.E.A...

Data Suggest CEL-SCI's CEL-2000 Vaccine Prevents or Retards Permanent Damage of Rheumatoid Arthritis

VIENNA, Va., Sept. 5 /PRNewswire-FirstCall/ -- CEL-SCI Corporation (Amex: CVM ) announced today that it presented new rheumatoid arthritis data at the Marcus Evans conference on Immunogenicity in Amsterdam. The data, presented by Dr. Daniel Zimmerman, Senior Vice President of Research, Cellul...

Results From One-Year Study Suggest Advair(R) Provides Important Benefits for African American Patients With Asthma

Results Suggested Improvements in Several Endpoints for Advair Diskus(R) Compared to ICS Alone RESEARCH TRIANGLE PARK, N.C., June 10 /PRNewswire/ -- African American patients with asthma treated with Advair Diskus, a combination of the long-acting beta-agonist (LABA) sa...

New Discovery of Key Difference in Bile Acid Metabolism in Patients with Type 2 Diabetes May Suggest Underlying Disorder

First Extensive Report of Bile Acid Aberration in Type 2 Diabetes Patients Warrants Further Study EMERYVILLE, Calif. and PARSIPPANY, N.J., June 9 /PRNewswire-FirstCall/ -- KineMed, Inc., and Daiichi Sankyo, Inc., announced that researchers have discovered a key differenc...

Final Data From the Bioheart Seismic Trial Suggest Safety, Efficacy of Autologous Stem-Cell Therapy for Treating Congestive Heart Failure

Leading Expert Discusses Study During Late-Breaking Presentations at ACC CHICAGO, April 1, 2008 /PRNewswire-FirstCall/ -- Bioheart, Inc. (Nasdaq: BHRT ) announced today that final six-month, follow-up patient data was presented today during the late-breaking clinical trial sessions at the Ame...

Final Data From the SEISMIC Trial Suggest Safety, Efficacy of Autologous Stem- Cell Therapy for Treating Congestive Heart Failure

Leading Expert Discusses Study During Late-Breaking Presentations at ACC CHICAGO, April 1, 2008 /PRNewswire/ -- Final six-month, follow-up patient data presented today during the late-breaking clinical trial sessions at the American College of Cardiology, suggest MyoCell(R) myoblast clinical c...

Recent Studies Suggest Popular 'Diet Pill' Relacore Reduces Acne Breakouts

NEW YORK, Feb. 15 /PRNewswire/ -- As crazy as it sounds, recent studies conducted at Stanford and Wake Forest Schools of Medicine suggest there's a connection between stubborn stress-related belly bulge, unsightly acne flare- ups and the so-called "Belly Fat" pill, Relacore(R) (from the Carter...

Arena Pharmaceuticals Announces APD668 Initial Clinical Study Results Suggest Glucose-Dependent Insulinotropic Receptors May Improve Glucose Control in Patients With Type 2 Diabetes

Ortho-McNeil to Continue Investigation of GDIR Agonists Under its Partnership with Arena SAN DIEGO, Jan. 7 /PRNewswire-FirstCall/ -- Arena Pharmaceuticals, Inc. (Nasdaq: ARNA ) announced today that initial clinical study results for APD668, an oral drug candidate di...

Pharmacokinetic Data Suggest NGX426, TorreyPines Therapeutics' Oral Prodrug of Tezampanel, May be Effective in Treating Acute Migraine Headache

- Company Plans to Initiate Phase IIa Study of NGX426 in Acute Migraine in First Half of 2008 - LA JOLLA, Calif., Dec. 10 /PRNewswire/ -- TorreyPines Therapeutics, Inc. (Nasdaq: TPTX ) today reported pharmacokinetic data obtained in a Phase I maximum tolerated dose cli...

Studies Suggest Key Correlation Between Lung Cancer Subtype and Treatment Outcomes

Lilly Studies Predictive Factors to Better Target Patients for ALIMTA(R) (pemetrexed for injection) in the Treatment of Non-Small Cell Lung Cancer BARCELONA, Spain, Sept. 25 /PRNewswire-FirstCall/ -- In clinical research, patients with advanced non-small cell lung cancer (NSCLC) that are clas...

Four Analyses of Three-Year Clinical Data Suggest CYPHER(R) Sirolimus-Eluting Coronary Stent May Provide Alternative to Surgery for Patients with Multivessel Disease

VIENNA, Austria, Sept. 5 /PRNewswire/ -- Four analyses of three-year follow-up data showed that the CYPHER(R) Sirolimus-eluting Coronary Stent may be considered an appropriate alternative to bypass surgery in patients with blockages in two or more coronary arteries (multivessel disease). The a...

New Data Suggest Cymbalta(R) Reduced Pain in Fibromyalgia Patients With and Without Depression

INDIANAPOLIS, Aug. 21 /PRNewswire-FirstCall/ -- New data suggest that patients with fibromyalgia treated with 60mg or 120mg of Cymbalta(R) (duloxetine HCl) experienced greater reduction in pain severity beginning one week after starting duloxetine than those taking placebo (sugar pill), as mea...

Data Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain

New Analysis Examines Impact of Pain on Sleep Interference INDIANAPOLIS, May 03, 2007 /PRNewswire-FirstCall/ -- Data from a pooled analysis of three studies suggest that in patients with pain caused by diabetic nerve damage, or diabetic peripheral neuropathy, who are treated with Cymbalta (duloxet...

Clinical Trial Results Suggest Long-Term Treatment Benefit of Tetrabenazine for Chorea Associated with Huntington's Disease

BOSTON--(BUSINESS WIRE)--May 3, 2007 - New data show the investigational drug tetrabenazine maintained reduction of chorea associated with Huntington's disease (HD) up to 80 weeks in those patients who successfully completed treatment in a 13-week trial. These data suggest that tetrabenazine can be...

Data Suggest that Pegasys May be an Option in Hepatitis C Patients Unable to Tolerate Peg-Intron

WASHINGTON--(BUSINESS WIRE)--May 21, 2007 - Roche today announced results of a small study demonstrating that all patients who discontinued treatment with Peg-Intron(R) (peginterferon alfa-2b) and ribavirin due to adverse events within the first 12 weeks, were able to complete 12 weeks of treatment...

Data Suggest Cymbalta Improved Functioning in Patients with Generalized Anxiety Disorder

Relationship Between Ability to Function and Treatment of Anxious and Painful Physical Symptoms Studied INDIANAPOLIS, May 21, 2007 /PRNewswire-FirstCall/ -- Data suggest that patients with generalized anxiety disorder (GAD) treated with Cymbalta(R) (duloxetine HCl) experienced improved ability to ...

Three Studies Suggest Abbott's Humira (adalimumab) May Improve Work Productivity in Patients with Rheumatoid Arthritis

One Groundbreaking Study Showed 11 Percent Fewer RA Patients Reported Job Loss When Treated With HUMIRA Combination Therapy Compared to Methotrexate Alone BARCELONA, Spain, June 15, 2007 /PRNewswire-FirstCall/ -- Rheumatoid arthritis (RA) is one of the most common causes of disability in the Weste...

Resveratrol Studies Suggest Broad Implications for SIRT1 Activation in Neurodegenerative Diseases of Aging Such as Alzheimer's Disease

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jun 26, 2007 - Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging, announced today that activation of SIRT1, a member of the sirtuin family of enzymes, was...

Clinical Data Suggest Decreased Bleeding Risk in People With Severe Hemophilia A While Maintaining Factor VIII Levels Above One Percent

Results Highlighted in Oral Presentation at International Symposium of Thrombosis and Haemostasis GENEVA, July 10, 2007 /PRNewswire-FirstCall/ -- Baxter Healthcare Corporation today announced the presentation of findings from the ADAPT (Analysis of Data from ADVATE(R) Prospective Trials) study pro...

Regular Yoga Practice Is Associated With Mindful Eating

...aid Kristal, who himself scored high on the mindful-eating survey and has a BMI within the normal range. Moving forward, Kristal and colleagues suggest that their Mindful Eating Questionnaire, the first tool of its kind to characterize and measure mindful eating, may be useful both in clinical practic...

TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

...d by the body as we reach middle age--replacing them with artificial GH, in theory, would slow the aging process. However, there is little evidence to suggest that it is effective. Very few studies have tested the combined effects of GH and sex-steroids on glucose tolerance, elevated cholesterol and...

Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms

...Overall Safety Profile (Lobo R, et al) Results from a sub-analysis suggest that treatment with BZA/CE significantly reduced the frequency and severity...increased BMD at the lumbar spine and total hip at 24 months. These results suggest that women in the BZA/CE groups gained bone mass while women in the placebo...

July 2009 Mayo Clinic Women's HealthSource Highlights Food Storage Safety, Energy Therapies and Vitamins and Minerals

...e body. Some people find healing touch relaxing. There's little evidence to suggest other health benefits. Qi gong: The Chinese word "qi gong" comb...could help lower the risk of some cancers and heart disease. Recent studies suggest that vitamin E supplements don't provide the same health benefits as dietar...

Poniard Pharmaceuticals Announces Positive Cardiac Safety Data From Picoplatin Phase 1 Trial Supporting NDA Filing

...resistance associated with chemotherapy in solid tumors. Study data to date suggest that picoplatin has an improved safety profile relative to existing platinum-based cancer therapies. Results to date suggest that hematologic events are common but manageable. Kidney toxicity (nephrot...

Idenix Pharmaceuticals Successfully Completes Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)

...25 mg cohort. Significant viral load reductions were observed in the three higher dose cohorts (50, 75 and 100 mg/day). Post-treatment viral load data suggest no evidence of drug accumulation. The table below summarizes mean HCV RNA reductions observed in this study per cohort: ...

Prospective Clinical Advantages of Trabecular Metal(TM) Technology Highlighted in Comparative Study

...e patients' osteolytic response to bearing surface particles, potentially further reducing the bony support for the implant. The authors of the study suggest that the elasticity (low stiffness) of Trabecular Metal material may induce a transfer of stresses to the periacetabular bone that more closely repl...

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

...ppears to correlate with disease severity. Preclinical and clinical studies suggest that belimumab can reduce autoantibody levels in SLE. BLISS 52 results suggest that belimumab can reduce SLE disease activity, and a second Phase 3 trial,...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

...nd in women called HPV-positive by the HC2 test. While further work to define clinically meaningful HPV detection thresholds is required, our results suggest that a type-specific, quantitative PCR-MS based test may be an important advance in the early detection of cervical cancer." Study Methodol...

PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it

...t normal aging, and is not completely based on genetics. "Our data suggest that American adults have limited knowledge and a poor understanding of fac...ared to non-drinkers with mild cognitive impairment. "Our findings suggest mild to moderate alcohol intake may reduce the risk of dementia," Sink said...

Landmark Study for GSK's Cervical Cancer Vaccine Published in The Lancet

...accine types in which HPV 16 and 18 was also detected, vaccine efficacy was 37.4 percent (7.4, 58.2; p=0.0092) in the ATP-E cohort. These two analyses suggest that the true vaccine efficacy against CIN 2+ associated with 12 non-vaccine cancer-causing HPV types lies between 37 percent and 54 percent T...

New AHRQ Study Finds Mixed Evidence on Use of Radiofrequency Catheter Ablation for Treating Atrial Fibrillation

...ignals may cause an arrhythmia to start. Different techniques and instruments can be used for the procedure. While there is no strong evidence to suggest that one particular technique is best for any given patient, there is general consensus concerning a basic approach to ablation procedures for atrial ...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

...better tolerated in the fed state. Also, the most frequently reported adverse effects (AEs) were those commonly associated with niacin. These findings suggest that niacin will be well tolerated up to 60 mg per dose and will likely be well tolerated at 90 mg per dose. Phase II Multiple-Dose Study of th...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

...th severe CNS diseases," said Iris Loew-Friedrich, Chief Medical Officer of UCB. "The positive results of the two Phase III trials are encouraging and suggest that subject to regulatory approval, this may offer a new treatment option for people with fibromyalgia." Only preliminary top-line efficacy and ...

Spherix Announces Positive Phase 2 Study Results

... that atherosclerotic lesions detected in TAG-fed mice were composed of increased collagen, indicative of a more stable plaque phenotype. The results suggest that, in addition to minimizing the extent of atherosclerosis from carbohydrate consumption, a diet enriched in tagatose may favor a more stable plaqu...

Conatus Pharmaceuticals Initiates a Second Phase 2 Clinical Trial for the Treatment of Hepatitis

...ls.gov (identifier NCT00925990) or http://clinicaltrials.gov/ct2/show/NCT00925990?term=cts1027&rank=2 "Our recent preclinical studies suggest that CTS-1027 treatment has the potential to impact the second phase of HCV virus inhibitory kinetics in patients. This phase is associated with the g...

ADHD Genes Found; Known to Play Roles in Neurodevelopment

... -- Missing DNA Segments May suggest Future Drug Targets -- PHILADELPHIA , June 23 /PRNewswire-USNewswire/...amine and serotonin, which are also neurotransmitters, this new finding may suggest an important role for glutamate as well, at least for some ADHD patients. ...

CRi Oosight(TM) Instrument Crucial in IVF Breakthrough Demonstrating a Correlation Between Non-Invasive Egg Metrics and Pregnancy

...occurs. The results are the first to show a direct link between egg spindle characteristics and pregnancy. "Extrapolation of these results would suggest that when a normal spindle is found, the chances of a pregnancy, if a high quality cleavage stage embryo follows, is greater than 65%," commented Dr. ...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

... Findings Published in Nature Medicine suggest Broad Implications for the Treatment of Inflammatory and Autoimmune Disorders SOUTH SAN FRANCISCO, Calif., June 15 /PRNewswire/ -- Proteolix, Inc...

New Studies Presented at European Society of Anaesthesia Further Validate Masimo PVI(TM) for Noninvasive and Continuous Fluid Monitoring

...he supine position again--researchers found a significant correlation between PVI and SVV (r = 0.75; p = 0.02). The study concluded that "Our results suggest that an accurate prediction of fluid responsiveness can be obtained non-invasively using the PVI."(1) The Change of Upper Limbs PVI in Spinal Bl...
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