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Artelis and Selexis Report Record Antibody Production Levels in CHO Cells of Over 31 Grams Per Liter

BRUSSELS, Belgium and GENEVA, Sept. 3 /PRNewswire/ -- Artelis SA and Selexis SA announced today a new milestone in CHO based monoclonal antibody production with the achievement of manufacturing yields of over 31 grams per liter. This record level was accomplished by applying two highly innovat...

Regular Yoga Practice Is Associated With Mindful Eating

... the participants practiced yoga more than an hour per week, 46 percent walked for exercise or transportation for at least 90 minutes per week and more than 50 percent engaged in more than...tes of moderate and/or strenuous physical activity per week. The average weight of the study parti...

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

...omen worldwide. In 2007, approximately 1.2 million cases of colorectal cancer were expected to occur globally. With more than 630,000 deaths worldwide per year, it is the second leading cause of cancer-related death in the Western world. The highest incidence rates are found in Japan, North America, part...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...s ended June 30, 2008. Basic and diluted net loss per share for the three months ended June 30, 2009 was $0.03 per share compared to $0.04 per share for the same period in 2008. Basic and dilu...

SIRO Clinpharm Completes Successful Implementation of Oracle Life Sciences Application Suite

...Siebel Clinical Trial Management System and Oracle Adverse Events Reporting System. "We are excited to have the rollout of the entire OLSAS as per our plan for the India operations," said Dr. Ajit Nair, President, India Operations, SIRO Clinpharm. "This will help us manage critical tasks in clini...

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

...ional supplementation requirements for osteoporosis of not less than 400 IU per day of Vitamin D and not less than 500 mg per day of calcium, which continued throughout the study. Treatment was randomi...

Nektar Therapeutics Reports Second Quarter 2009 Financial Results

...ter ended June 30, 2009 was $32.1 million or $0.35 per share, compared to net loss of $33.4 million or $0.36 per share in the second quarter of 2008. Nek...NTS OF OPERATIONS (In thousands, except per share information) (una...

ARUP Laboratories Applauds FDA's Decision on the Value of KRAS-Mutation Testing in Colorectal Cancer

...ich can identify nearly all of the patients who will not benefit from taking either Vectibix or Erbitux. These drugs cost tens of thousands of dollars per course of therapy and simply running ARUP's KRAS mutation-detection test can potentially eliminate ineffective patient treatment and decrease health...

Study Shows Brain Fitness can Save Medicare Billions

...ng projected Medicare costs by hundreds of dollars per year. As the number of Medicare enrollees grows fr...nts predicted healthcare costs that were $244 less per patient than in the control group, after adjustmen...ower predicted healthcare costs by about $143 less per year (or $128 on an unadjusted basis.) "Thi...

Scientists Discover Origin of Malaria

...saving lives today, but for the health of people for many generations to come." Every year malaria: Accounts for 500 million cases per year. Results in more than one million deaths -- mostly children. Includes 1,300 cases in the United States. Cuts economic growth by...

Pharmasset Reports Positive Preliminary Antiviral Data With PSI-7851 for the Treatment of Hepatitis C

...in HCV RNA. Patients were randomized to receive either PSI-7851 (8 patients per cohort) or placebo (2 patients per cohort). Three dose cohorts of PSI-7851 (50mg QD, 100mg QD, 200mg QD) were ...

July 2009 Mayo Clinic Women's HealthSource Highlights Food Storage Safety, Energy Therapies and Vitamins and Minerals

...nd raise high-density lipoprotein (HDL or "good") cholesterol. However, the doses needed for these effects, usually greater than 1,000 milligrams (mg) per day, can cause liver damage. High doses of niacin should be considered a prescribed medication and taken only under a doctor's supervision. ...

Cardica Announces Publication of Pivotal PAS-Port(R) Proximal Anastomosis System Clinical Trial Results

...G) procedures. "The data published this month confirm that the PAS-Port system produces comparable patency, saves approximately five minutes per connection and eliminates the need to clamp the aorta required for hand-sewn connections," commented John D. Puskas, M.D., chief of cardiac surgery at...

Idenix Pharmaceuticals Successfully Completes Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)

...y). Post-treatment viral load data suggest no evidence of drug accumulation. The table below summarizes mean HCV RNA reductions observed in this study per cohort: End of Treatment Mean Patients with 1 log10 or Change in HCV RNA Grea...

Exenatide Once Weekly Provided Superior Glucose Control Compared to Lantus(R) in Head-to-Head DURATION-3 Study

... of those affected have type 2 diabetes. Diabetes is the fifth leading cause of death by disease in the U.S. and results in approximately $174 billion per year in direct and indirect medical expenses.(iii) According to the Centers for Disease Control and Prevention's National Health and Nutriti...

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

...imumab treatment groups, versus placebo, had their average prednisone dose reduced by at least 25% from baseline to 7.5 mg per day or less during the last 12 weeks of study (p=0.053 for 10 mg/kg and p=0.025 for 1 mg/kg belimumab, respectively vs. pl...

AlphaVax Announces Results from Initial Testing of Its H1N1 (Swine) Influenza Vaccine

...HO. We are currently scaling up the process used to manufacture VRP vaccines and anticipate yields up to 1 million doses of pandemic influenza vaccine per lot at the 1,000 L bioreactor scale. Since the process is performed predominantly in disposable equipment, the design, construction and validation of ...

BioCryst Pharmaceuticals Reports Positive Results of Shionogi & Co. Sponsored Phase 3 Studies of i.v. Peramivir for Influenza

...c respiratory disease requiring pharmacotherapy, or current treatment with any immunosuppressive drug. Peramivir was administered at 300 mg or 600 mg per day, and the duration was adjusted (up to five days) on a case-by-case basis, depending on the patient's temperature and clinical condition. In this ...

Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV

... treatment. The study is being conducted in two stages, with the first stage initiated in January 2008 and having enrolled 95 patients (47-48 per treatment arm). Following 24 weeks of treatment, a formal interim analysis was conducted and the safety results were reviewed by an independent Data ...

Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing

...sure (measured by area under the curve or AUC). Delivering a compound twice per day generally allows for more consistent concentration levels in the blood.... levels (peaks) do not reach as high as when the compound is delivered once per day. "When we assessed the pharmacokinetics in patients taking ed...

Results From Drug Trials and New Risk Factors Announced at International Alzheimer's Conference

...ntia associated with PTSD. A second study suggests lower Alzheimer's risk among adults who consume moderate amounts of alcohol (1 or 2 drinks per day), versus those who do not drink or who are heavy drinkers. However, this does not appear to be true for those who already have mild cognitive impa...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

...al cancer. Today, more than 10 million HPV DNA tests are conducted annually, and the total number of HPV DNA tests is growing at a rate exceeding 35% per year. Many have predicted a HPV DNA test capable of genotyping and quantifying HPV DNA will one day supplant the Pap smear as the primary screening t...

PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it

... with 18% of respondents making more than $200,000 per year at the peak of their careers, and well-educat... counted. The distribution of alcohol consumption per week was 0=42.6%; 1-7=38.2%; 8-14=9.4%; more than ...ine cognition, moderate alcohol intake (1-2 drinks per day) was associated with a 37% lower risk of demen...

Results From Trials of DHA in Alzheimer's Disease and Age-Related Cognitive Decline

...pants had a dietary DHA intake of less than 200 mg per day. Subjects were treated with DHA or placebo at a dose of two grams per day for 18 months. Those participants already taki...six month study to determine the effects of 900 mg per day of algal DHA on improving cognitive functions ...

Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)

... position, product development and business strategy, as well as estimates of future net sales, future expenses, future net income and future earnings per share. Statements including words such as "believes," "expects," "anticipates," "intends," "estimates," "plan," "will," "may," "intend," "guidance" o...

Shoulder Surgery Doesn't Prevent Return to Sports

... no matter their age. "Eighty-eight percent of the individuals in our study returned to their activity levels for periods greater than 30 minutes per session with the same type of intensity. It also appears that the most likely reason for returning to the same level of participation is dependent on ...

FDA Accepts sNDA for Alternative Dosing Regimen for Dacogen(R) (decitabine for injection) to Treat Patients with Myelodysplastic Syndromes (MDS)

...hree-day regimen, administered at a dose of 15 mg/m2 via continuous IV infusion over three hours repeated every eight hours for three consecutive days per cycle. The cycle is repeated every six weeks. The alternative five-day dosing regimen of Dacogen(R) submitted to the U.S. FDA is a single daily dose ...

Denosumab Demonstrates Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Breast Cancer Patients With Bone Metastases

... denosumab subcutaneously every four weeks (Q4W) or Zometa administered intravenously at a dose of 4 mg single, 15 minute infusion every four weeks as per the labeled use. In clinical trials testing new medications for bone metastases, treatment success has been measured by whether the bone complic...

USC Keck School of Medicine's Dr. Alan Epstein Receives Prestigious National Cancer Institute RAID Award for Breakthrough IL-2 Molecule Therapeutic

...a in 2007, with an estimated additional 48,000 or more cases of melanoma in situ. The current lifetime risk for developing invasive melanoma is 1 case per 60 Americans. Currently, IL-2 is the only FDA approved immunotherapeutic agent. But while the current therapy provides unparalleled recovery fo...

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

...Retinopathy Study (ETDRS) scale; the scores at study end were similar in both treatment groups (Lantus(R): 14.2%, NPH: 15.7%; 95% CI: -7.02, 3.06). As per protocol, the study aimed to achieve similar levels of glycemic control in both groups, in order to avoid introducing bias on the primary retinopathy ...

BioCis Pharma Reports Positive Phase IIa Clinical Results in Atopic Dermatitis

...kin disorders." Atopic dermatitis is a chronic inflammatory disease of the skin with an onset typically already in infancy. It affects up to 20 per cent of the general population in the Western countries, and the prevalence rate is rising. Atopic dermatitis may significantly impair the quality of ...

New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF

...ms of costs per treatment cycle, but also in costs per live births." Health economic data T...hs (2) average cost of treatment; (3) average cost per live-birth; (4) incremental cost-effectiveness; (5.... The use of HP-hMG resulted in a saving of GBP875 per patient cycle, a saving that could finance an addi...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

...ndomised, placebo-controlled, multi-centre trials involving 1,192 patients from 23 countries. Patients had a history of at least four partial seizures per month despite treatment with up to three concomitant anti-epileptic drugs. During the trials, patients were randomised to various dosages of ES...

King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use

...acin. These findings suggest that niacin will be well tolerated up to 60 mg per dose and will likely be well tolerated at 90 mg per dose. Phase II Multiple-Dose Study of the Safety and Tolerability of...

Spherix Announces Positive Phase 2 Study Results

... The subjects were also given 75 g of tagatose followed 30 minutes later by 75 g of glucose. Between test days, participants received 10 g of tagatose per day. Ingestion of the tagatose load (75 g) caused no increase in plasma insulin or glucose concentrations in either healthy or diabetic individuals. ...

West Wireless Health Institute Teams with Corventis for its First Multicenter, Randomized Clinical Trial

...-hospitalized within 30 days. The cost burden to the health system for these readmissions is profound and estimated to be in the range of $10 Billion per year. With the newfound ability to monitor multiple highly relevant physiologic parameters on a continuous 24/7 basis -- such as heart rhythm, fl...

GeoVax Labs, Inc. Announces Results of 2009 Annual Shareholders Meeting

...e predominant subtype in North America where there are roughly 60,000 new infections each year. Globally, there are about 2.5 million AIDS infections per year, most primarily involving subtypes AG, B, and C. In 2007, UNAIDS reported 1.3 million people living with AIDS in North America and 33.2 million p...

CoAxia, Inc. Announces $21.5M Series D Financing

...ology has the potential to become integrated into the standard of care for stroke treatment, and thus treat more than 500,000 ischemic stroke patients per year - resulting in a market in excess of $1B. The purpose of the Series D financing is to provide sufficient funds for CoAxia to complete the SE...

HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

...r. Slade. "Based on an estimated 2.5 million venous leg ulcers in the United States alone and actual direct treatment costs reported to be over $9,000 per patient, the current annual cost of treating these wounds is likely in the many billions of dollars." "We are excited to be working with HEALTHP...

Neurocrine Biosciences Presents Elagolix Data

...fects of elagolix. The results of this study showed that daily administration of elagolix induced partial suppression of gonadotropins for 12-18 hours per day with a return to baseline each morning for 42 days. The effect on gonadotropins translated in a dose related fashion to maintenance of low estradi...
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