Amarin Proceeding to Phase 3 With AMR101 for Hypertriglyceridemia
...back has been achieved. Having completed our recent financing, we now
look forward to conducting the Phase 3 program."
AMR101 is an ultra-pure ethyl
ester of eicosapentaenoic acid
(Ethyl-EPA). Amarin has collected a substantial body of data on AMR101 to
date. Amarin has previously investigated AMR101 in ...
Study Published in Endocrinology Reports Potential of Modigene Technology to Extend Duration of Protein Drugs
...Peptide of Human Chorionic Gonadotropin b-Subunit to the Coding Sequence of Human Erythropoietin," Fuad Fares, Sherif Ganem, Taleb Hajouj, and
ester Agai, Endocrinology 148(10):5081-5087. The study is currently available in the on-line edition of the journal. ABOUT MODIGENE Modigene Inc. (OT...
Presentations at American College of Cardiology Meeting Highlight
New Opportunities for HDL Therapy
...th Pfizer's HDL raising drug, torcetrapib were presented.
Torcetrapib is a member of a class of drugs which increase HDL by
inhibiting the cholesterol
ester transfer protein (CETP).
ILLUMINATE, a morbidity and mortality trial comparing the clinical
efficacy and safety of torcetrapib/atorvastatin (Lipitor) ...
RTA 402 Shown to Inhibit STAT3 in Animal Model and Holds
Significant Promise for Treating Breast Cancer
...nd that the drug inhibits signaling activity of STAT3, an
important target for new cancer therapies.
The article, "The Novel Triterpenoid C-28 Methyl
ester of
2-Cyano-3, 12-Dioxooleen-1, 9-Dien-28-Oic Acid Inhibits Metastatic
Murine Breast Tumor Growth through Inactivation of STAT3
Signaling," was authore...