Neurointerventionists Expand Research to Quality of Life in Aneurysm Patients Following Minimally Invasive Coiling Treatment
...nvasive coiling has been proven many times over in the case of intracranial aneurysms (a bulge in the artery wall which can suddenly burst, leading to
bleeding in the brain that may result in severe disability, or even death), less is known about the psychosocial functioning of these patients after unde...
Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms
...y when compared to placebo. In this study, uterine
bleeding was not statistically different from placebo...onjugated Estrogens (BZA/CE): Incidence of Uterine
bleeding in Postmenopausal Women (Archer DF, et al) ...ate the effect of treatment with BZA/CE on uterine
bleeding, trial participants were asked to record in ...
Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing
...ceiving edoxaban once daily (QD) experienced fewer
bleeding events than patients given edoxaban twice a day (BID). The analysis finds that
bleeding associated with edoxaban is most closely cor...ood, and that these trough levels may best predict
bleeding events, rather than total exposure or maximu...
Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (mesalamine) Delayed-Release Tablets
...ms, including number of bowel movements and rectal
bleeding, for some as early as three weeks. Asacol HD...four of patients by six weeks and decreased rectal
bleeding for approximately 80 percent of patients by ...derately active UC, Asacol HD helped reduce rectal
bleeding and stool frequency, without the use of ster...
New AHRQ Study Finds Mixed Evidence on Use of Radiofrequency Catheter Ablation for Treating Atrial Fibrillation
...tween patients treated with the approved ablation catheters versus patients treated with medication. This study will analyze total mortality, serious
bleeding and cardiac arrest.
Also, last week, the FDA approved a new medication, dronedarone, for treatment of atrial fibrillation. For more inform...
ThromboGenics and BioInvent Start Recruitment of Second 100 Patient Cohort in Phase II DVT Prophylaxis Study With TB-402
...de. This novel mode of
action is expected to reduce the risk of undesirable
bleeding events, even at
high doses, as well as the need for patient monitorin...icoagulants are still inconvenient and
associated with an increased risk of
bleeding. Improved anticoagulants are
therefore required. In particular, agent...
Current Status of the Development Programs of New Indications and Formulations for Aricept(R) for Enhancing Patient Value
...r everyone. People at risk for stomach ulcers or who take certain other medicines should tell their doctors because serious stomach problems, such as
bleeding, may get worse. Some people who take Aricept may experience fainting. Some people may have nausea, vomiting, diarrhea, bruising, or not sleep w...
New Study Shows that Prebiotics, as Used by Jackson GI Medical, Increases Lifespan by 33%
... in cholesterol and body weight versus the control group.
Significantly, the prebiotic used in the study was oligofructose enriched inulin, a
blend of two prebiotics which has repeatedly shown synergistic health benefits versus the more common single-prebiotic fibers such as plain inulin.
...
ProFibrix Initiates Phase II Clinical Trial of its Lead Topical Hemostat Product Fibrocaps(TM)
...t, with
the successful treatment of the first patients for mild to moderate
bleeding
during liver surgery. ProFibrix expects to complete the study before ...ombin, and is a unique dry powder topical tissue sealant
that rapidly stops
bleeding after or during surgery. Fibrocaps has major
advantages over existing...
Neurocrine Biosciences Presents Elagolix Data
...rrhea), sexual intercourse (dyspareunia) as well as chronic pelvic pain throughout the menstrual cycle. Infertility and abnormally heavy and prolonged
bleeding (menorrhagia) are also common of which, in combination with pain, contribute to more than 100,000 hysterectomies performed annually. The annual ...
New Analysis Shows Efficacy of SIMPONI(TM) (golimumab) in Anti-TNF Experienced Rheumatoid Arthritis Patients
... body may not make enough blood cells to help fight infections or help stop
bleeding. Your doctor will check your blood counts before and during treatment. Tell your doctor if you have signs such as fever, bruising,
bleeding easily, or paleness.
Rarely, people using TNF blockers have deve...
Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis
... body may not make enough blood cells to help fight infections or help stop
bleeding. Your doctor will check your blood counts before and during treatment. Tell your doctor if you have signs such as fever, bruising,
bleeding easily, or paleness.
Rarely, people using TNF blockers have deve...
Two New Clinical Studies Show That Limited Exposure to Blood Transfusion Significantly Increases Morbidity and Mortality After Surgery
...nagement techniques and "more appropriate indicators" for transfusions.
Blood transfusions may be necessary to ensure survival when a patient is
bleeding heavily or has severe symptomatic anemia. However, transfusions are also given in the presence of stable anemia or when significant blood loss i...
Heparin Use Prior to Endoscopic Vein Harvest Improves Graft Patency in Off-Pump Coronary Artery Bypass Patients
...techniques that involve a long incision to expose the entire length of the vein.
"In our experience, the impact of pre-heparinization on surgical
bleeding is minimal, making it a promising strategy that may improve patient outcomes with minimally invasive vein harvesting," said lead investigator Ro...
Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting
...active-controlled clinical trials in patients with
blepharospasm and cervical dystonia -- one placebo-co...a for the indications of symptomatic management of
blepharospasm, cervical dystonia and post-stroke spas... the pooled data from 2 pivotal clinical trials in
blepharospasm and cervical dystonia (343 NT 201 patie...
WORLD'S First Robotic Assisted Kidney Transplant Performed at Saint Barnabas Medical Center
...ial to the patient in terms of quicker recovery, as well as a lower incidence of the most frequent post-operative complications -- wound infection and
bleeding," states Dr. Geffner.
For Jim and Maureen Schrader, it was transformational.
When Jim and Maureen met five years ago, they knew they ...
New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease
... but often include abdominal pain and tenderness, frequent diarrhea, rectal
bleeding, weight loss and fever. There is currently no cure for Crohn's disea... tiredness.
Blood disorders - fever that doesn't go away, bruising,
bleeding or severe paleness.
Nervous system disorders - numbness, weak...
Horizon Therapeutics' HZT-501 Significantly Reduces Incidence of NSAID-Induced Upper Gastrointestinal Ulcers in Patients With Mild-to-Moderate Pain
...reating pain, but they also increase the risk of developing ulcers in the stomach or intestine and the risk of developing ulcer complications, such as
bleeding. Patients at increased risk for gastrointestinal ulcers may benefit from protective co- therapy, although many such patients do not receive or ...
Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer
...nia and neutropenia were more frequent and severe with the FOLPI regimen compared with FOLFOX. However, only one episode of febrile neutropenia and no
bleeding complications have been observed to date. In addition, 83 percent of the planned picoplatin dose of 150 mg/meter squared was able to be delivere...
Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types
...ated bilirubin, drop in platelets count, diarrhea,
bleeding, cardiac ischemia, elevated liver function t...ess commonly reported side effects include vaginal
bleeding, blood clots, other cancers, osteoporosis, s...were reported to have severe gastrointestinal (GI)
bleeds and/or intratumoral...
Classwide Opioids REMS: A Good Idea, Implement Carefully
...cribe drugs not encumbered by the REMS even though they might be less optimal, and put patients at risk for adverse consequences like gastrointestinal
bleeds or liver disease," said Sidney H. Schnoll, M.D., Ph.D., Vice President, Risk Management, Pinney Associates, and Clinical Professor, Internal Medic...
Boston Scientific Welcomes Results of Brain Aneurysm Clinical Trial
...ns," said Dr. Molyneux, Principal Investigator for ISAT. "The risk of late
bleeding from a coiled aneurysm is very low, which has been a clinically unans...via catheter through the blood vessels into the aneurysm to prevent further
bleeding into the brain. Surgical clipping is an open intervention involving ...
Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)
... to seek immediate medical attention if they develop signs and symptoms suggestive of blood dyscrasias or infection (e.g., persistent fever, bruising,
bleeding, pallor) while on CIMZIA. Consider discontinuation of CIMZIA therapy in patients with confirmed significant hematologic abnormalities.
A n...
Cadence Pharmaceuticals Submits Acetavance New Drug Application for the Treatment of Acute Pain and Fever
...available in the United States is the NSAID, ketorolac. Post-operative use of intravenous ketorolac is limited due to its potential to cause increased
bleeding. Renal toxicity and the potential for increased cardiovascular events further limit the post-operative use of NSAIDs. Dipyrone (metamizole) was ...
New Studies Show Popular Heartburn Medications Moderate the Effect of Taking Widely Prescribed Heart Drug
...e often taken along with clopidogrel to reduce the risk of gastrointestinal
bleeding, a possible side-effect of the antiplatelet drug. While 41 percent o...were prescribed a PPI, a negligible number of them had experienced a severe
bleeding problem.
"There's a growing body of evidence that PPIs decrease...
New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel
...that rates on non-CABG-related TIMI major or minor
bleeding did not significantly differ by genetic vari...sus 12.1 percent), with an increased risk of major
bleeding by 32 percent compared with clopidogrel (2.4...ercent), which included life-threatening and fatal
bleeding.(3)
About Acute Coronary Syndromes ...
Potentia Pharmaceuticals' POT-4 Drug Candidate for Age-Related Macular Degeneration Successfully Completes Phase I Clinical Trial - Prepares for Phase II
...pproach geared towards the approximately 10-15% of AMD patients with complications resulting from ocular angiogenesis (growth of new blood vessels and
bleeding in the back of the eye). No drug currently on the market has been approved for the treatment of the remaining patients, who suffer from the so-c...
Pharmaxis Announces Positive Results of Phase 3 Cystic Fibrosis Trial
...-701
Email: felicity.moffatt@pharmaxis.com.au
United States:
Brandon Lewis
Trout Group
Tel: +1-646-378-2915
Email:
blewis@troutgroup.com
...
Isis and Collaborators Present New Research at the ATVB Annual Conference
...ate a drug to decrease clotting without increasing
bleeding. Both of these programs are expected to pro...in models of stroke without causing an increase in
bleeding, the most common side effect observed with c...timal target to inhibit thrombosis without causing
bleeding. In addition to Factor XI, we will have dru...
Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients
...ter studies in patients with cervical dystonia and
blepharospasm, and pooled European efficacy and safet...a for the indications of symptomatic management of
blepharospasm, cervical dystonia and post-stroke spas...linum neurotoxin free from complexing proteins) in
blepharospasm .
Joseph Jankovic, M.D. Professor...
Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting
...ntenance study. The primary efficacy measure for the study was time to development of first clinical event, defined as liver decompensation (variceal
bleeding, Child-Pugh class C, grade 2 or higher hepatic encephalopathy, ascites requiring therapeutic paracentesis and/or additional therapy), developmen...
Phase 3 Trial of Nexavar in Chemotherapy-Naive Patients with Advanced Melanoma Does Not Meet Primary Endpoint
...ing the first six weeks of therapy and treated as needed. In HCC patients,
bleeding with a fatal outcome from any site was reported in 2.4% for Nexavar a...n was 2.7% for Nexavar vs. 1.3% for placebo. In RCC patients, incidence of
bleeding regardless of causality was 15% for Nexavar vs. 8% for placebo and th...
Oakwood Surgeons Perform World's First 3D Surgery Without Special Glasses
...and full service radiology including advanced CT and MRI.
The Oakwood Heritage team consists of professional healthcare specialists who provide a
blend of quality care, professionalism and great customer service. In 2007, OHH received its second consecutive Gold Seal of Approval from The Joint Comm...
Prometheus and Rosetta Genomics Announce License and Collaboration Agreement
...stology, i.e. squamous or non-squamous NSCLC, have demonstrated histologic-specific response patterns ranging from a high incidence of severe or fatal
bleeding in the lungs to poor response to treatment. Current methods for differentiating squamous from non-squamous NSCLC are not standardized, are diffi...
PEAK Surgical Announces Completion of First PRECISE Clinical Study, Receipt of Medical Design Excellence Award for PEAK(R) Surgery System and Achievement of Over 1,000 Surgeries Using PEAK PlasmaBlade(TM)
...scalpels precisely cut tissue, they do not control
bleeding. Electrosurgical devices, on the other hand, cut efficiently and control
bleeding but cause extensive thermal damage to surrou... devices offers the precision of a scalpel and the
bleeding control of a traditional electrosurgery devi...
Study Data Show Positive European Experience With DuraHeart Left Ventricular Assist Device for Advanced Stage Heart Failure Patients
...ond generation axial flow LVADs. The event rate of
bleeding requiring surgery (0.22 per patient-year) wa... of adverse events, including fatal intra-cerebral
bleeding (75 percent) and other
ble eding complications was observed in the first 11 p...
Pharmaxis Announces Milestone in Phase III Trial for Cystic Fibrosis
...8-677-701
Email: felicity.moffatt@pharmaxis.com.au
United States:
Brandon Lewis, Trout Group
Tel: +1-646-378-2915
Email:
blewis@troutgroup.com
Web: http://www.pharmaxis.com.au
...
QuatRx Completes Enrollment of Ophena(TM)(Ospemifene Tablets) Final Pivotal Phase 3 Study in Women with Postmenopausal Vaginal Atrophy
... to lose elasticity, a condition known as vaginal atrophy. Dryness and irritation associated with reductions in vaginal secretions often cause pain or
bleeding during sexual intercourse. It is estimated that 45-75 percent of postmenopausal women experience chronic symptoms of vaginal atrophy which are b...
Schering-Plough Announces Results of the Early ACS Trial
...points of the trial. Significantly higher rates of
bleeding and transfusions also were reported.
"T...th or (re)MI at 30 days. Safety endpoints included
bleeding and transfusions through 120 hours.
No ...oup (p=0.079).
Significantly higher rates of
bleeding were observed in the study group, with 118 p...
AHRQ-Funded Study Finds Lower Risk of Death and Heart Attack in Patients With Drug-Coated Stent Implants Compared to Those With Bare Metal Stents
...red a repeat angioplasty or coronary artery bypass graft surgery (roughly 23 percent) and in the percentages of patients who suffered strokes or major
bleeding (about 3 percent and 3.5 percent, respectively). The results were not affected by age, gender, race, ethnicity or other factors.
Accordin...