arm in Medical Technology

VA Studies Advanced Prosthetic Arm

New Mobility for Veterans, Service Members, Other Americans WASHINGTON, May 27 /PRNewswire-USNewswire/ -- The Department of Veterans Affairs (VA) has announced a three-year study of an advanced artificial arm that easily allows those with severe limb loss to pick up a key or hold a pencil. ...

New Results From ARTEN Study of Nevirapine Plus Tenofovir and Emtricitabine (TDF/FTC) Versus Boosted Protease Inhibitor Regimen of Atazanavir/Ritonavir Plus TDF/FTC Revealed

...t in the ATV/r group. Discontinuation due to adverse events was 13.6 percent in the nevirapine arms (51 of 376 patients), and 3.6 percent in the ATV/r arm (7 of 193 patients).(4) These results include patients who received once-daily nevirapine (400 mg). Nevirapine is not indicated for once-daily dosing...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

...zyme replacement therapy (ERT) or who have not received ERT for at least six months prior to the start of treatment with Amigal. The Amigal treatment arm dose and regimen will be 150 mg every other day. The primary endpoint will be the change in the amount of kidney interstitial capillary GL-3 as...

Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th

...d that three additional patients in the pixantrone arm achieved a CR and one additional patient achieved ... p=0.009). No patient in the standard chemotherapy arm achieved a confirmed complete remission at this po...rapy (14 of 70 patients (20.0%) for the pixantrone arm compared to four of 70 patients (5.7%) for the sta...

Jennerex Therapeutic Research Collaboration With Ottawa Hospital Research Institute Selected for $10 Million Grant From Ontario Institute for Cancer Research

...nistry of Research and Innovation. About the Ottawa Hospital Research Institute The Ottawa Hospital Research Institute (OHRI) is the research arm of The Ottawa Hospital and is an affiliated institute of the University of Ottawa , closely associated with the University's Faculties of Medicine an...

Data Demonstrated ACTEMRA(R) (tocilizumab) Significantly Inhibited Progression of Structural Joint Damage in Rheumatoid Arthritis Patients

... 8 mg/kg plus methotrexate achieved ACR20, ACR50 and ACR70, respectively, and 47 percent, 29 percent and 16 percent of patients in the ACTEMRA 4 mg/kg arm achieved these ACR scores, respectively. In contrast, 25 percent, 10 percent and 4 percent of patients in the control group achieved ACR20, ACR50 and...

Enrollment in Delcath's Pivotal Phase III Metastatic Melanoma Clinical Trial Achieves Seventy-Five Percent Accrual

...U.S. Food and Drug Administration under a Special Protocol Assessment (SPA), when disease progresses in patients enrolled in the best alternative care arm of the trial, they are permitted to "cross over" and receive treatment with the Delcath System. About Delcath Systems, Inc. Delcath Systems, ...

SCAI Statement on the BARI 2D Trial (Bypass Angioplasty Revascularization Investigation With Diabetes Trial) Presented at the American Diabetes Association (ADA) Annual Scientific Sessions and Published in The New England Journal of Medicine

...ngioplasty and stenting. DES are imperative for most diabetic patients who require angioplasty. Many patients enrolled in the revascularization/PCI arm of BARI-2D received bare metal stents because DES were not available in the early years of this trial. Diabetes patients must be screened fo...

Boehringer Ingelheim Unveils Diabetes Pipeline

...randomized patients, 268 patients received double-blind treatment with linagliptin (1 mg, n=65; 5 mg, n=66; 10 mg, n=66) or placebo.(1) An open-label arm with 65 patients on glimepiride was added for descriptive control.(1) Additional results from the study The addition of linagliptin to met...

Pixantrone Produces High Rates of Complete and Partial Remissions Even Among Aggressive NHL Patients With Extensive Prior Doxorubicin Treatment or Prior Rituximab Treatment

...nts achieving a CR/CRu on the pixantrone treatment arm (n=14) had a significant increase in the duration ... (14 out of 70 patients (20.0%) for the pixantrone arm compared to four out of 70 patients (5.7%) for the....02) with no patients in the standard chemotherapy arm achieving a confirmed complete remission. The...

Keryx Biopharmaceuticals Announces Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

...s were evaluable for response (20 patients on the capecitabine + perifosine arm and 15 patients on the capecitabine + placebo arm). The three patients not...citabine patient group is ongoing with 10 of the 20 patients in this arm still alive. Dr. Howard Burris, Chief Medical Officer and Direc...

TNFerade(TM) Phase III Data Presented at ASCO

...e appeared to be safe and well-tolerated. The analysis also indicated a 25% reduction in the risk of death in the TNFerade plus standard-of-care (SOC) arm compared to the patients receiving SOC alone (Hazard Ratio = 0.75; 95% Confidence Interval [0.494 - 1.15]). Dr. Mark Thornton, GenVec's Senior V...

Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients

.... 65%, respectively). Patients on the gemcitabine arm experienced significantly more grade 3/4 toxicities. Additionally, two patients on the gemcitabine arm died due to causes possibly attributed to treatmen...aseline characteristics between both. Patients on arm A were treated with cisplatin (40 mg/m(2)) and gem...

Keryx Biopharmaceuticals Reports Positive Data from a Randomized, Multi-Center, Placebo-Controlled, Phase 2 Combination Study of KRX-0401 (Perifosine) in the Treatment of Advanced Metastatic Colon Cancer

...s were evaluable for response (20 patients on the capecitabine + perifosine arm and 15 patients on the capecitabine + placebo arm). The three patients not...apecitabine patient group is ongoing with 10 of the 20 patients in this arm still alive. Dr. Howard Burris, Chief Medical Officer and D...

Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer

...rtial response and 27 patients with stable disease. In the FOLFOX treatment arm of 50 patients, 76 percent achieved disease control; three patients with a ...e to be delivered monthly in the 51 patients treated in the FOLPI treatment arm of the trial. Nonhematologic adverse events, including gastrointest...

First Jatropha Genome Completed by Synthetic Genomics Inc. and Asiatic Centre for Genome Technology

...erhad/ACGT Asiatic Development Berhad ("Asiatic"), a 55%-owned subsidiary of Genting Berhad, commenced its operations in 1980 as the plantation arm of the Genting Group. Over the years, the Asiatic Group had embarked on several significant acquisitions in Malaysia, thus increasing its land bank fr...

Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma

...t-line treatment of RCC in combination with sunitinib. Agennix's RCC submission included the results from a Phase I trial, and a multi-center, single arm Phase II trial of talactoferrin in 44 patients with clear cell RCC who had failed standard therapy. Patients receiving oral talactoferrin in this Pha...

Cardium Announces Completion of Patient Recruitment in Phase 2b Clinical Trial of Excellarate(TM) for the Potential Treatment of Diabetic Foot Ulcers

...igned to evaluate safety and efficacy in patients receiving one or two doses of Excellarate compared to placebo controls. A standard of care reference arm is also included in the study. The primary endpoint of the study is complete wound closure at or before the initial 12-week study period. Other key ef...

Brain Training Improves Memory and Attention and the Effects Last

...new pathways in response to the right kind of stimulation. Marlene Allen, aged 75, of Mill Valley, California participated in the brain exercises arm of the study. "Now I don't have to write down shopping lists. I remember what I need at the store," Ms. Allen said. "And I almost never walk into a ro...

Data Presented at AUA Demonstrate PROVENGE Significantly Prolongs Survival for Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study

... adjustment for docetaxel use following investigational therapy (HR=0.763; p-value=0.036). Prostate cancer-specific survival also favored the PROVENGE arm (HR=0.772; p-value=0.036). Consistent with other trials in this patient population, PROVENGE did not significantly delay time to progression. The ad...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

...mary efficacy analysis, 36 patients in the control arm and 27 in the treatment arm had clinical events (P=0.14), a non-statistically ...lysis there were 87 clinical events in the control arm and 63 in the treatment...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...128 1000mg bid in combination with PEGASYS and COPEGUS for 12 weeks, followed by a further 36 weeks of PEGASYS and COPEGUS ("12+36") A control arm with PEGASYS and COPEGUS for 48 weeks. Patients in the 24-week arms will discontinue all treatment at week 24 if they have achieve...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...EBETOL for 48 weeks. SVR for the low-dose REBETOL arm was 36 percent (n=21/59) compared to 50 percent for a 48-week control arm with PEGINTRON and standard-dose REBETOL plus boce... was used by 26 percent of patients in the control arm and 39-51 percent of patients in the boceprevir ar...

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

.... baseline). In comparison, tumor growth was observed across the saline control, unconjugated CLIP 71 and cisplatinum arms. In addition, in the EP-100 arm tumor volumes, weights and CA125 (a clinical biomarker for ovarian cancer) were reduced. LHRH receptor levels were also reduced and PET imaging reveal...

Genetic Source of Rare Childhood Cancer Found; Gene is Implicated in Other Cancers

...S News & World Report and the Leapfrog Group. For more information, visit www.childrensnational.org . Children's Research Institute, the academic arm of Children's National Medical Center, encompasses the translational, clinical, and community research efforts of the institution. Learn more about ou...

Glycotex' Investigational Compound GLYC-101 Achieves Accelerated Wound Closure Based on Interim Analysis

...kin resurfacing on the lower eyelid area. The interim analysis was conducted after 26 subjects completed the study. The comparison of each active arm to placebo with respect to the primary endpoint (time to complete wound closure) shows positive results when considering the full dataset of patient d...

MitraClip(R) Therapy Data Shows Important Clinical Benefit in High Risk Patients With Functional Mitral Regurgitation at 12-Month Follow Up

...nal mitral regurgitation (FMR) improves patient clinical status, and left ventricular function, according to 12-month data from the high-risk registry arm of the EVEREST II (Endovascular Valve Edge-to-Edge REpair STudy) study presented today at the 58th Annual Scientific Session of the American College o...

Joint Statement from the American Diabetes Association and American Association of Clinical Endocrinologists on the NICE-SUGAR Study on Intensive Versus Conventional Glucose Control in Critically Ill Patients

...ems reasonable for clinicians to treat critical care patients with the less intensive - yet good - glucose control strategies used in the conventional arm of the NICE-SUGAR trial. About The NICE -SUGAR Study Hyperglycemia in the hospital, whether it occurs in patients with known diabetes or i...

A Joint Statement From America's Prostate Cancer Advocacy, Education, and Support Organizations

... years has been an enormous commitment by all concerned. * We enthusiastically support the continued follow-up of patients in the prostate cancer arm of the PLCO study for at least a further 5 years, through 2014, as originally envisaged. In addition, in the long-term interests of the health o...

Schering-Plough's Investigational Oral Thrombin Receptor Antagonist Meets Primary Endpoint in a Newly Published Study

...d with PCI, the incidence of TIMI major and minor bleeding was 3 percent in both the collective TRA treatment arms and the current standard care alone arm (p=0.7713). Non-TIMI bleeding was also not significantly increased with TRA compared to current standard care alone (p=0.0650). Overall, TRA was wel...

AMA Foundation Announces Seed Grant Research Recipients

... The Seed Grant Research Program was established to encourage more physicians to enter the field of research. As the philanthropic arm of the AMA, the AMA Foundation supports a broad range of programs in medical education and public health. Please visit www.amafoundation.org or cal...

Elbow Ligament Reconstruction Appears Not to Affect Future Professional Advancement in Baseball

..."Our data shows that UCL reconstruction prior to selection in the MLB draft does not appear to increase the chances of a future injury to the throwing arm or impact a player's professional prospects when compared to a matched control group. Our analysis is sufficiently powered to detect large differences...

Staying One Step Ahead of Osteoporosis

... in adults, maybe a tip off or early warning sign, that osteoporosis could be an issue. Many of these are painful fractures of the hip, spine, wrist, arm and leg, which often occur as a result of a fall or even a simple household task. One in two women and one in five men older than 65 years old, will ...

Beating Blood Clots after Joint Replacement

...e convenient to the patient and offer tremendous potential in preventing a DVT. Whether or not these new agents become available, the best way to arm against this problem, Dr. Friedman suggests, "is to mobilize patients as early as possible to stimulate blood flow, be sure they understand that a pro...

Children and Orthopaedic Surgical Emergencies

...swelling or deformity is almost always associated with a fracture. When you believe your child may have any type of serious injury or fracture of the arm or leg, it is important to get them to a hospital quickly," noted Dr. Herman. Note: This topic will be the focus of a Media Briefing entitl...

American Academy Of Orthopaedic Surgeons 2009 Annual Meeting 'Highlights and Hot Topics'

... injuries. Family members, even distant relatives who have suffered tears to the rotator cuff, the muscles and tendons that hold the top of the upper arm bone in place, appear to create an increased risk for others on the same family tree to also develop a torn rotator cuff. This risk extends out to th...

Dr. James F. Pingpank to Present at Leading Regional Therapies Conference

...U.S. Food and Drug Administration under a Special Protocol Assessment (SPA), when disease progresses in patients enrolled in the best alternative care arm of the trial, they are permitted to "cross over" and receive treatment with the Delcath System. The Fourth International Symposium on Regional C...

New England Journal of Medicine Publishes Results from Boston Scientific's Landmark SYNTAX(TM) Trial

...scularization), however, was significantly higher for PCI (17.8 percent versus 12.4 percent, p=0.002), due to more repeat revascularization in the PCI arm (13.5 percent versus 5.9 percent, p=0.001). Most repeat revascularizations in the PCI arm, however, were performed by additional PCI, with only 2.8 p...

Compared to Standard Therapies, Pixantrone Decreases Time to Achieve Complete Remission by 47% in Relapsed Aggressive Non-Hodgkin's Lymphoma

...l (PFS) was significantly longer in the pixantrone arm (4.7 months vs. 2.6 months, hazard ratio = 0.6; p ...ess frequent in the pixantrone than in the control arm (1.5% vs. 13.4%). "We were impressed to see...tandard chemotherapy (14/70 (20.0%) for pixantrone arm compared to 4/70 (5.7%) for the standard chemother...

Fifth U.S. Hand Transplant Patient Heads Home to NY

... Lead hand transplant surgeon Dr. Breidenbach said, "Erik continues to work on mobility exercises and strengthening the muscle groups in the hand and arm using light weights. Functional activities for grasping, releasing and pinching continue to improve, as well. He can perform such daily living activi...