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VAS in Medical Technology

Iontophoretic Drug Delivery System (IDDS) Containing Lidocaine and Epinephrine is Effective in Reducing Pain Associated With Insertion of an Intravenous Catheter in a Phase 2 Clinical Trial

...edure were 16.4 mm for the Active treatment versus 24.0 mm for the Placebo treatment (p=0.0235). Therefore, the trial demonstrated statistically lower vas scores for the Active group as compared to the Placebo group. In addition, more than 80% of the Active group reported pain elimination and willingness...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

...to endpoint based on the Pain Visual Analog Scale (VAS). Data from the Fibromyalgia Impact Questionnaire (FIQ) are considered equally relevant as Pain vas data in the E.U. FIQ data are considered supportive data by U.S. regulators. In the top-line results, significantly more patients treated with so...

Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

...eduction in pain as measured by at least a 30% improvement in baseline pain vas score, compared with 35.2% of patients taking placebo using Last Observatio...rly as Week 1 after dosing compared with placebo as measured by the Fatigue vas (p<0.001). These differences were maintained throughout the 14 weeks of...

Ferring Pharmaceuticals Unveils Six-Month Efficacy Data for EUFLEXXA(R) for the Treatment of Osteoarthritis Knee Pain

...means of -6.6 mm (P=0.002). At 26 weeks, 145 (58%) of EUFLEXXA(R) subjects reported a greater than or equal to 20-mm improvement in pain based on the vas scoring, compared with 120 (46%) in the other group (P=0.006). The percentage of Osteoarthritis Research Society International (OARSI) responders for...

Oh, My Aching Back: Give Me a Shot of Ozone

..., dressing or standing (with 61 percent or higher representing back pain that has an impact on all aspects of daily living. The improvement scores for vas and ODI outcomes are well above both the minimum clinically important difference and the minimum (statistically significant) detectable change, indica...

Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain

...ore of 0-100 with 0 equal to no pain and 100 equal to maximal pain. The percentage of patients who were free of ocular pain/discomfort, reflected by a vas score of 0, was superior and statistically significant for the Durezol groups versus the placebo groups in both the QID and BID studies as early as Da...

Transdel Enrolls First Patient for Ketotransdel(TM) Phase 3 Clinical Trial

...pain" and 100 indicates "the worst imaginable pain." The secondary endpoints will include safety assessments and other efficacy parameters measured by vas at Day 3 and Day 7. In addition to evaluating for efficacy and safety over the one week period, the study will also assess safety at one week post-tre...

Neurocrine Biosciences Announces Successful Elagolix PETAL Study in Endometriosis

... 2.2 Week 24 mean -1.2* -1.2* -1.1* Responder Rate 86% 77% 77% vas 78.7 Week 24 mean -31.8* -33.4* -35.5* *ITT Analysis, p<0.0001 ...

Innocoll Announces Dosing of Last Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-Operative Pain

...results of this trial were particularly encouraging, showing evidence of sustained, post-operative analgesia for approximately 96 hours as measured by vas (visual analogue scale) scores and reduced dependence on systemic morphine administered by PCA (patient-controlled analgesia). This extended analgesic...

Orthokine Treatment is Effective for Knee Arthritis, Even After Two Years

...hokine group had the fewest patients who went on to seek further treatment. Patients who received Orthokine treatment had the greatest improvements in vas and WOMAC scores. For the WOMAC test in particular, the outcomes were as follows: Starting from an initial WOMAC score of 124, the Orthokine group saw...

Targeted Genetics Announces Positive Phase 1/2 tgAAC94 Data Presented at Annual European Congress of Rheumatology

...ient-reported pain and functional scores as measured by the global visual analog scale (VAS) in the tgAAC94-treated arm versus the placebo arm. Global vas is a clinically meaningful and commonly used assessment tool to help patients describe the intensity of their pain and functional capacity. About Ta...

Anesiva Announces Publication of Phase 3 Zingo(TM) Data in the Journal Pediatrics

...isual analog scale (VAS), was also used in patients eight to 18 years old, and patients who received Zingo also reported significantly lower vas scores (22.62) compared to sham placebo (31.97) (p -- Parents of patients who received Zingo also rated their child's pain as significantl...

Parion Sciences Announces Phase I Clinical Results for Novel Dry Mouth Treatment

...e in visual analog scale (VAS) measurements 12 hours after dosing at day 7 and day 28 revealed significant improvement in the global dry mouth scores. vas scores that measured the change at day 28 in mouth dryness, tongue dryness and ability to sleep also indicated that subjects improved on P-552-02 comp...

Innocoll Announces Dosing of First Patient in US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain

...results of this trial were particularly encouraging, showing evidence of sustained, post-operative analgesia for approximately 96 hours as measured by vas (visual analogue scale) scores and reduced dependence on systemic morphine administered by PCA (patient- controlled analgesia). This extended action w...

Anesiva Announces Pivotal Phase 3 Trial of Zingo(TM) Meets Primary Endpoint and Significantly Reduces Venous Access Pain in Adults

...e or IV line placement at the back of hand or antecubital fossa (crux of the elbow). The primary endpoint was pain upon needle insertion utilizing the vas pain scale. Demographic characteristics and sites of administration were evenly distributed across treatment groups. The mean pain score in the Zingo...

Dharma Therapeutics Shows IDDS Is Effective in Reducing Pain Associated With Insertion of an Intravenous Catheter in Their Phase 2 Clinical Trial

...ment of the intravenous catheter, subjects evaluated their pain using the vas scoring system and were asked if they would use the IDDS again. Investiga...s. Safety of the treatment was also monitored. Results: Median vas scores were reduced by 58%, a highly significant reduction in perceived p...

New Data Suggests Less Abuse-Related Effects For OROS Methylphenidate

...alog Scales (VASs). The magnitude of scores on the vas scales was ranked (lowest to highest) as placebo <...release (IR) MPH 50 mg and < IR MPH 90 mg. For the vas Drug Liking scores, OROS(R) MPH 54 mg was signific...8 mg was consistently lower than IR MPH 90 mg. For vas Good Effects and...

New Data Focuses on Abuse of Stimulant Medication

...S(r) methylphenidate formulation. Pharmacodynamics of potential abuse were assessed with Visual Analog Scales (VASs). The magnitude of scores on the vas scales was ranked (lowest to highest) as placebo< OROS(r) methylphenidate (MPH) 54 mg, <0.05) doses MPH IR comparable than scores lower significant...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

...inically significant levels of pain (mean baseline vas scores >30 mm) were seen across all vas pain measures prior to switching. Switch to dulo...eatment groups. Mean improvements in each of the vas pain scores, expressed as a percentage of baseline...

Neurogen Proprietary Insomnia Compound Data for Two Studies Presented at Associated Professional Sleep Societies Annual Meeting

...and posturography. Zolpidem 10 mg had effects that appeared similar to a dose between 3 mg and 5 mg of NG2-73. The duration of action of NG2-73 in the vas ranged from approximately 1.5 hours for the 1 mg dose to approximately 6 hours with the 10mg dose. Zolpidem had a duration of action of approximately ...
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