Antibiotics Don't Prevent Future Urinary Tract Infections, May
Cause Resistance in Future Infections
PHILADELPHIA, July 10, 2007 /PRNewswire-USNewswire/ -- After afirst childhood urinary tract infection (UTI), daily antibioticsmay not
prevent another such infection, and may actually increasethe risk that the next urinary tract infection is caused byresistant bacteria, according to a new study in the July 11 issueof the Journal of the American Medical Association. In the first larg...
Phase III Trial Results Show Superiority of Rivaroxaban over
Enoxaparin for the Prevention of Venous Thromboembolism in Patients
Undergoing Knee Replacement Surgery
Rivaroxaban, a New Oral, Once-Daily Direct Factor Xa Inhibitor,Shows a Significant Reduction in Deep Vein Thrombosis and PulmonaryEmbolism Compared with Enoxaparin with Similarly Low BleedingRates GENEVA, July 8, 2007 - Late-breaking Phase III clinical trialdata presented today at the XXI International Society on Thrombosisand Haemostasis (ISTH) Congress demonstrate that once-daily...
Phase III Trial Results Show Superiority of Rivaroxaban over
Enoxaparin for the Prevention of Venous Thromboembolism in Patients
Undergoing Knee Replacement Surgery
GENEVA--(BUSINESS WIRE)--Jul 8, 2007 - Late-breaking Phase IIIclinical trial data presented today at the XXI InternationalSociety on Thrombosis and Haemostasis (ISTH) Congress demonstratethat once-daily rivaroxaban achieved superior efficacy in the
prevention of venous thromboembolism (VTE) in patients undergoingknee replacement surgery in a head-to-head comparison withenoxaparin, the curren...
Peer Reviewed Journal Article Indicates Repros' Proellex Exhibits
Potential for New Approach to the Treatment and Prevention of
Breast Cancer
THE WOODLANDS, Texas--(BUSINESS WIRE)--Jul 5, 2007 - ReprosTherapeutics Inc. (NasdaqGM:RPRX) today announced that an articlehas been published in the July 1, 2007 issue of Oncology Reportsindicating a potential for a new approach to the treatment ofbreast cancer using Proellex. The article reviews the findings froma study conducted in an accepted in vivo rat model of breastcancer. The study...
Vaccine Can Prevent Cervical Cancer and Precancerous Lesions
LONDON, June 28, 2007--A cervical cancer vaccine has shown 90%efficacy for
prevention of cervical cancer and precancerous lesionsassociated with the human papillomavirus (HPV) types targeted bythe vaccine, conclude authors of an Article published early Onlineand in the upcoming issue of The Lancet. HPV types 16 and 18 account for 70% or morecases of cervical cancer worldwi...
Insmed Inc. Welcomes Studies Linking IGFBP-3 to Prevention of
Blindness in Premature Infants
RICHMOND, Va.--(BUSINESS WIRE)--Jun 26, 2007 - Insmed Incorporated(Nasdaq:INSM), a biopharmaceutical company focused on thedevelopment and approval of drugs for the treatment of metabolicdiseases with unmet medical needs, today noted the publication ofpromising results of research from three universities regarding thepotential role of insulin-like growth factor binding protein-3(IGFBP-3) in...
Accera, Inc. Announces Open-Label Data from Phase II Study in
Alzheimer's Disease at International Conference on Prevention of
Dementia
BROOMFIELD, Colo., June 11, 2007 /PRNewswire/ -- Accera, Inc.today is presenting data from an open-label extension of its PhaseIIb clinical trial of AC-1202 (Ketasyn) in Alzheimer's disease (AD)at the Alzheimer's Association's International Conference on
Prevention of Dementia in Washington, D.C. Consistent with thefindings of earlier clinical and preclinical studies, AC-1202 wasshown to...
At the 2007 Alzheimer's Association International Conference on the
Prevention of Dementia - Neurochem's U.S. Principal Investigator
Presents Update on Tramiprosate (Alzhemed)
WASHINGTON, DC, June 11, 2007 /PRNewswire-FirstCall/ - Paul S.Aisen, M.D., Professor of Neurology and Medicine at GeorgetownUniversity Medical Center, and principal investigator in the UnitedStates of Neurochem Inc.'s North American Phase III clinical trialfor tramiprosate (ALZHEMED(TM)) will present today an update onNeurochem's investigational product candidate for the treatment ofAlzh...
Frova Phase III Study Data Demonstrates That Short-Term Prevention
Treatment Reduces Frequency and Severity of Menstrual Migraine
CHICAGO, IL, Jun 09, 2007 (MARKET WIRE via COMTEX News Network)-- Endo Pharmaceuticals Inc., a wholly owned subsidiary of EndoPharmaceuticals Holdings Inc. (NASDAQ: ENDP), has presented resultsfrom a Phase III randomized, double-blind, placebo-controlledclinical trial evaluating Frova (frovatriptan succinate) 2.5 mgtablets as a six-day
preventative treatment in women withdifficult-to-tre...
New Research Confirms the Benefit of Extended-Release Dipyridamole
Plus ASA for Preventing Recurrent Stroke in Low- and High-Risk
Patients
Aggrenox® (Asasantin® Retard) considered by many asfirst-line in secondary stroke
prevention INGELHEIM, Germany, 31 May 2007 - New data presented today at the16th European Stroke Conference in Glasgow confirm that therapywith dipyridamole plus ASA (extended-release dipyridamole plus ASAis marketed as Aggrenox® or Asasantin® Retard) is superiorto ASA* alone in...
Investigation Findings, Corroborated by Empirical Evidence of the
Schisandra Berry as Cardio-Tonic in Traditional Chinese Medicine
for Hundreds of Years, Support the Use of Schisandrin B in the
Prevention and Treatment of IHD
SEATTLE--(BUSINESS WIRE)--May 29, 2007 - Mitopharm Corporation,Inc. (Pink Sheets:MTPM), releases the results of a research paperwhere Professor Dr. Robert Ko published the beneficial effects ofSchisandrin B, the precursor of (-) Schisandrin B - a noveldiscovery by Dr. Ko - on Ischemic Heart Disease. In a research paper entitled "SCHISANDRIN B PROTECTS AGAINSTMYOCARDIAL ISCHEMIA-REPERFUSIO...
Senate Passes Drug-Safety Reforms to Prevent Future Vioxx-type
Disasters; House Urged to Act on Strong Drug Safety Bill
First significant drug safety measure in 45 years; focus moves toHouse WASHINGTON, May 09, 2007 /PRNewswire-USNewswire/ -- The Senatetoday overwhelmingly passed significant prescription drug safetyreforms to give the Food and Drug Administration more power to dealwith unsafe medicines on the market, moving the issue of drugsafety to the House, where a strong bill has been introduced buth...
Data Published in The Lancet Show Gardasil was 100 Percent
Effective in Preventing High-Grade Vulvar and Vaginal Lesions
Caused by HPV Types 16 and 18
WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)--May 17, 2007 - Resultspublished this week in The Lancet show that Merck's cervical cancervaccine, GARDASIL (Quadrivalent Human Papillomavirus (Types 6, 11,16, 18) Recombinant Vaccine) was 100 percent effective in
preventing high-grade vulvar and vaginal dysplasias caused by HPVtypes 16 and 18, two types strongly associated with these diseases.The 10...
MedImmune Announces Positive Clinical Results at PAS Annual Meeting
From Large Prospective Trial in Prevention of Serious RSV Disease
- Numax Achieves Primary Endpoint Among High-Risk Infants VersusCurrent Standard of Care and Shows Reduction of Medically AttendedOutpatient RSV- Related Lower Respiratory Infections - TORONTO, May 08, 2007 /PRNewswire-FirstCall/ -- MedImmune, Inc.today announced positive results from a large prospective trialconducted for
prevention of respiratory syncytial virus (RSV). Thetrial compared...
Multiferon Shows Potent Activity in Preventing the Progression of
Malignant Melanoma; Study to be Published
PLANTATION, Fla., May 08, 2007 /PRNewswire-FirstCall/ --Viragen, Inc. and Viragen International, Inc. today announcedresults from a sponsored in vitro study conducted at UmeaUniversity in Sweden, which found that Multiferon(R) (multi-subtype, human alpha interferon) suppressed development ofresistant human melanoma clones to a far greater degree thanrecombinant alpha interferon. The stud...
St. Jude Study Shows Effectiveness of Peramivir in Prevention of
Mortality in Mouse Model of Avian Influenza H5N1 Virus Infection
BioCryst Says Study Confirms and Extends Evidence Seen in aPrevious Study BIRMINGHAM, Ala., May 02, 2007 /PRNewswire-FirstCall/ --BioCryst Pharmaceuticals, Inc. today announced that investigatorsat St. Jude Children's Research Hospital, Memphis, TN, reportedfavorable results evaluating peramivir treatment in an animal modelof influenza using a highly virulent strain of H5N1 virus (an avia...
deCODE Announces Positive Topline Results for Phase I Study of
DG051 for the Prevention of Heart Attack
REYKJAVIK, Iceland, May 01, 2007 /PRNewswire-FirstCall/ --deCODE genetics today announced positive top-line results from itsPhase I multiple dose clinical trial of DG051, which the company isdeveloping for the
prevention of heart attack. In the study, arandomized, double-blind, multi- dose, ascending dose,placebo-controlled clinical trial, a total of 40 healthy subjectswere exposed to DG...
Ties Between Physicians and Drug Companies Still Too Strong: the
Prescription Project Offers Solutions to Prevent Conflicts of
Interest
BOSTON--(BUSINESS WIRE)--Apr 26, 2007 - A new study published todayin the New England Journal of Medicine ("A National Survey ofPhysician-Industry Relationships") on the extent of doctor andpharmaceutical company relationships, highlights the need forprofession-wide and public policy reforms promoted by ThePrescription Project. The article concludes that the existing,voluntary PhRMA (Pharma...
Columbia Laboratories Reports Preliminary Findings from the Ongoing
Data Analysis of the Phase III Clinical Study of PROCHIEVE 8%
(progesterone gel) to Prevent Preterm Birth
LIVINGSTON, N.J.--(BUSINESS WIRE)--Apr 26, 2007 - ColumbiaLaboratories, Inc. (NASDAQ: CBRX) today announced that preliminaryresults from the ongoing data analysis of the recently-completedrandomized, placebo-controlled, double-blind Phase III clinicaltrial of PROCHIEVE(R) 8% (progesterone gel) for the
prevention ofpreterm birth in women with a previous preterm birth earlier than35 weeks ges...
Onconase has Potential as Chemopreventive Agent in Mesothelioma,
Reports World-Renowned Mesothelioma Researcher at AACR Annual
Meeting
BLOOMFIELD, N.J., April 18, 2007 /PRNewswire-FirstCall/ --ONCONASE (ranpirnase), Alfacell Corporation's lead drug candidate,may have potential as a chemo
preventive agent, according toworld-renowned mesothelioma researcher Michele Carbone M.D., Ph.D.,at this week's American Association for Cancer Research (AACR)Annual Meeting. In a series of poster presentations, Dr. Carbone highlig...
Inotek Pharmaceuticals Announces Publication of Animal Data from
Study of PARP Inhibition as Potential Preventative of Brain Injury
Following Stroke
BEVERLY, Mass.--(BUSINESS WIRE)--Apr 10, 2007 - InotekPharmaceuticals Corporation announced today the publication in thejournal Stroke of preclinical animal data showing that theadministration of a poly(ADP-Ribose) polymerase (PARP) inhibitorhas a large protective effect on the survival of certain braincells following a stroke. PARP is a nuclear enzyme that directs therepair of damaged DNA...
Portola Pharmaceuticals Announces Positive Phase II Results for
PRT054021 for Prevention of Venous Thromboembolism Following Total
Knee Replacement Surgery
Data to be Presented at the XXI Congress of the InternationalSociety on Thrombosis and Haemostasis SOUTH SAN FRANCISCO, Calif., April 04, 2007 /PRNewswire/ --Portola Pharmaceuticals, Inc. today announced that it has receivedpositive results from EXPERT, a Phase II study of its oral FactorXa inhibitor, PRT054021, for the
prevention of venousthromboembolism (VTE) following total knee replac...
Immunosuppressant Drug Prevents Tobacco Induced Lung Cancer in Mice
BETHESDA, Md., April 1, 2007--Rapamycin, an FDA-approved drugnormally used to help
prevent the body from rejecting organ andbone marrow transplants and also used to coat cardiac stents, washighly effective in
preventing the development of tobacco-relatedlung tumors in mice. In a study published in the April 1, 2007issue of Clinical Cancer Research, researchers at the NationalCancer Insti...
Six Important Things to Know About Preventing Hospital Infections
Infection Control Professional Offers Patient Tips to Guard AgainstHospital Infections KANSAS CITY, Kan., April 02, 2007 /PRNewswire/ -- Hospitalinfections are among the top ten leading causes of death in theUnited States, according to the Centers for Disease Control. Thereare countless stories about patients who go into hospitals withminor conditions and leave under much graver circumsta...
Inflazyme Announces Outcome of Review of Phase 2b Asthma Study:
Potential Mitigating Factors Identified which Prevent Clear
Interpretation of Results
RICHMOND, British Columbia, March 12, 2007--InflazymePharmaceuticals Ltd. (TSX: IZP). As announced on January 29, 2007,the preliminary results of the Phase 2b CAPSICS study withIPL512,602 showed no statistical or clinical difference betweenpatients who received drug or placebo. However, the placeboresponse was surprisingly large and consistent across a number ofthe end-points, which prom...
GenoMed Prevents Sickle Cell Pain for Over a Year
ST. LOUIS--(BUSINESS WIRE)--Mar 12, 2007 - GenoMed (OTC PinkSheets:GMED), the Next Generation Disease Management company whosebusiness is public health(TM), announced today publication of acase report of a sickle cell patient whose pain has disappeared forover a year thanks to GenoMed's treatment. The patient is a middle-aged African American woman who foryears required multiple pain pill...
Ceragenix Announces Ceragenins Virtually Prevent Catheter Biofilm
Formation in 21 Day Study
DENVER--(BUSINESS WIRE)--Mar 12, 2007 - Ceragenix Pharmaceuticals,Inc. (OTCBB:CGXP), a biopharmaceutical company focused oninfectious disease and dermatology, today announced that a cathetertreated with a Ceragenin compound demonstrated virtually no biofilmformation in a 21 day study. In the study, polyurethane catheters treated with Cerageninswere soaked daily in a phosphate-suffered sol...
Study in Cell by Magen BioSciences Co-Founder David E. Fisher
Identifies New Roles in Skin Cancer Prevention for Key Tumor
Suppressor Protein
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Mar 8, 2007 - Magen BioSciences,Inc., a specialty dermatology company, today announced thepublication of a paper in the March 9, 2007 issue of the journalCell by its co-founder and board member, David E. Fisher, M.D.,Ph.D., that identifies two new functions for an important protein,p53, in the pigmentation of skin. Fisher's study shows that inaddition to i...