Response Genetics Announces Publication of a Phase III Clinical
Trial Demonstrating That Low Levels of ERCC-1 Help to Predict
Likelihood of Response to Cisplatin-Based Therapy in Lung Cancer
- First prospective biomarker trial in non-small cell lung cancer - LOS ANGELES, July 09, 2007 /PRNewswire-FirstCall/ -- ResponseGenetics, Inc. today announced that positive Phase III clinicaldata published in the July 1 issue of the Journal of ClinicalOncology suggests that low expression of the biomarkerExcision-Repair Cross-Complementing 1 (ERCC-1) in patient biopsieswith advanced non-...
Mayo Clinic News Release: Mayo Clinic-led Study Improves Breast
Cancer Risk Prediction in Women with Atypia
ROCHESTER, Minn., July 2, 2007-Women with at least three sites ofcellular atypia in breast tissue are nearly eight times more likelythan average women to develop breast cancer, according to findingsof a Mayo Clinic Cancer Center led study of women with atypicalhyperplasia. The findings are published in the July 1 issue of theJournal of Clinical Oncology. Several previous studies have show...
New Analysis of WHI Data Shows Reduced Levels of Coronary Artery
Calcification, a Predictor of Cardiovascular Events, in Women aged
50-59 taking Estrogen Therapy
LINCOLNSHIRE, Ill.--(BUSINESS WIRE)--Jun 21, 2007 - BioSantePharmaceuticals, Inc. (AMEX:BPA) today provided comment on theWomen's Health Initiative (WHI) Coronary Artery Calcium Studypublished yesterday in The New England Journal of Medicine (NEJM).The study found that younger menopausal women (aged 50-59) whoreceived a standard dose of estrogen therapy had significantly lesscoronary artery...
ApoCell's Cancer Predictive Index Helps Oncologists Select the Most
Effective Targeted Drug Therapy
HOUSTON--(BUSINESS WIRE)--Jun 7, 2007 - ApoCell, Inc. presented theresults of a study conducted by researchers at the University ofChicago and ApoCell at the 2007 annual meeting of the AmericanSociety of Clinical Oncology (ASCO) held in Chicago in early June.The study showed that ApoCell's advanced pharmacodynamic biomarkerassay technology provides reliable
predictive data of clinicalrespon...
Introgen Reports Updated Phase 2 Advexin Data Correlating Improved
Survival, Tumor Responses and Predictive p53 Biomarker
CHICAGO--(BUSINESS WIRE)--Jun 4, 2007 - Introgen Therapeutics, Inc.(NASDAQ: INGN) and the Company's clinical collaborators todayreported updated Phase 2 data demonstrating a significantcorrelation between abnormal p53, tumor responses and increasedsurvival following ADVEXIN(R) therapy in patients with recurrentsquamous cell carcinoma of the head and neck. The data (Abstract#6057) were prese...
ARRIVE Registry Analysis Identifies Predictors of Stent Thrombosis
in Real-World Use of Drug-Eluting Stents
Study highlights importance of antiplatelet therapy compliance NATICK, Mass. and BARCELONA, Spain, May 22, 2007/PRNewswire-FirstCall/ -- Boston Scientific Corporation todayannounced results from an analysis of more than 7,000 patients fromits ARRIVE 1 and 2 registries, designed to assess the performanceof the TAXUS(R) Express2(TM) paclitaxel- eluting coronary stentsystem in "real-world" p...
Indivumed Study Provides Sound Scientific Basis for a Predictive
Drug Test- Platform
HAMBURG, Germany, May 03, 2007 /PRNewswire/ -- At the April AACRAnnual Meeting, Indivumed presented data which provide a soundscientific basis for a new drug test-platform to
predict drugresponse in patients. Tumor tissue-derived primary cell lines are currently the firstchoice for cancer drug testing. During their clonal selection andexpansion, however, their gene and protein expr...
Millennium Discovers Biomarkers Potentially Predictive of Response
to Velcade (Bortezomib) for Injection
- Findings Published in Blood Highlight Millennium Leadership inPersonalized Medicine and Could Strengthen the Role of VELCADE asFoundation of Therapy in Broad Range of Multiple Myeloma Patients - CAMBRIDGE, Mass., April 17, 2007 /PRNewswire-FirstCall/ --Findings published in the April 15th issue of Blood show that ateam of researchers led by Millennium Pharmaceuticals, Inc. hasdiscovered...
New Data Show Early Non-Response to Antipsychotic Treatment May Be
Strong Predictor of Subsequent Non-Response for People with
Schizophrenia
Findings indicate early non-responders unlikely to subsequentlyrespond, have substantially more treatment costs, and may benefitfrom earlier change in treatment strategy COLORADO SPRINGS, Colo., April 03, 2007 /PRNewswire-FirstCall/-- New data presented at the 2007 International Congress onSchizophrenia Research (ICOSR) suggest that antipsychotic drugresponse be assessed earlier than is p...
Large Study Shows that Presence of Neutralizing Antibodies Did Not
Predict Clinical Response to Betaseron Treatment
WAYNE, N.J., April 02, 2007 /PRNewswire/ -- Berlex, Inc., a U.S.affiliate of Bayer Schering Pharma AG, Germany, announced today theresults of a retrospective study demonstrating that the presence ofneutralizing antibodies (NAbs) that can develop in response toBetaseron(R) (interferon beta-1b) therapy did not
predict clinicalresponse in patients with multiple sclerosis (MS).(1) The studyl...
Study Presented at the ACC Shows Inflammatory Enzyme Lp-PLA2
Predicts Heart Disease Risk in Metabolic Syndrome Patients
NEW ORLEANS--(BUSINESS WIRE)--Mar 26, 2007 - Study results showthat elevated lipoprotein-associated phospholipase A2 (Lp-PLA2), acardiovascular-specific inflammatory enzyme associated withunstable plaque that can lead to heart attack and stroke, isespecially
predictive of heart disease risk in patients with themetabolic syndrome--a serious medical condition that affects nearly50 million Ame...