New Therapy Enlists Immune System to Boost Cure Rate in a Childhood Cancer

--In a First, Immunotherapy Works Against Neuroblastoma-- PHILADELPHIA, May 28 /PRNewswire-USNewswire/ -- A multicenter research team has announced encouraging results for an experimental therapy using elements of the body's immune system to improve cure rates for children with neuroblastoma...

New Study Shows Probiotic Strain Effective in Boosting Immune Response to Flu Virus

Bacillus coagulans boosts a key immune marker in healthy people CLEVELAND, May 5 /PRNewswire/ -- A new study in the current issue of Postgraduate Medicine suggests that a specific strain of probiotics , Bacillus coagulans GBI-30, PTA-6086, increases the body's immune response to the flu ...

An Independent Study Reports on the Utility of ImmuKnow(R), the Cylex(TM) Immune Cell Function Assay, for Monitoring Heart Transplant Recipients

The results of the largest study performed to date will be presented during the International Society for Heart and Lung Transplantation Annual Meeting in Paris, France on April 24, 2009 COLUMBIA, Md., April 24 /PRNewswire/ -- Since it was cleared as an in vitro assessment of cell-mediate...

Laser Burn Injuries in One Eye Can Disrupt Protective Immune Privilege in Both Eyes, Study Finds

Findings have implications for treating returning vets and others exposed to laser burns BOSTON, Feb. 26 /PRNewswire-USNewswire/ -- Scientists at Schepens Eye Research Institute have shown for the first time that a laser burn to one retina can cause both eyes to lose a special protective abil...

Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

First and Only Approved Platelet Producer in Europe Represents New Treatment Approach for Serious Chronic Autoimmune Disorder ZUG, Switzerland, Feb. 6 /PRNewswire-FirstCall/ -- Amgen (Nasdaq: AMGN ) today announced that the European Commission (EC) has granted marketing authorisation for Np...

Study Demonstrates that AHCC(R) Enhances Immune System by Increasing the Production of Key Dendritic Cells

Proves significance of AHCC for maintaining a healthy immune system PURCHASE, N.Y., Jan. 6 /PRNewswire/ -- A recently published study in Nutrition and Cancer (60(5), 643-651) by researchers at Kansai Medical University in Osaka, Japan has shown that AHCC (Active Hexose Correlated Compound) ...

IBT Laboratories Expands its Menu of Tests for Immune Deficiency

LENEXA, Kan., Dec. 2 /PRNewswire/ -- IBT Laboratories, a leading clinical-diagnostics and biomedical-research laboratory specializing in immunology and allergy assays, announced that it has launched two tests to evaluate the response of patients whose immune systems may be compromised due to a ...

Parasites That Live Inside Cells Use Loophole to Thwart Immune System

A study from St. Jude scientists shows how microbes can block nitric oxide production - a chemical key to the immune system - and offers hints for fighting bacteria MEMPHIS, Tenn., Nov. 3 /PRNewswire-USNewswire/ -- St. Jude Children's Research Hospital scientists have discovered a mechanism ...

Symposium Highlights Yale Study Indicating Role of AHCC(R) for Immune System Enhancement and as a Promising Cancer Preventative

Significant Research Presented at the AHCC International Research Symposium PURCHASE, N.Y., Sept. 16 /PRNewswire/ -- The 16th International AHCC(R) (Active Hexose Correlated Compound) Symposium was held in Sapporo, Japan on July 26th and 27th. The Symposium hosted by the AHCC Research Associatio...

Study Demonstrates That AHCC(R) Provides Immune Enhancement Against the West Nile Virus

Proves promising for individuals living with West Nile Virus and populations susceptible such as the elderly or immune compromised PURCHASE, N.Y., Sept. 9 /PRNewswire/ -- A recently completed study from researchers at Colorado State University supported by the Division of Vector-Borne In...

Preclinical Study Presented at AACR Annual Meeting Shows Peregrine's Anti-PS Immunocytokines Can Generate Protective Immune Responses in a Highly Aggressive Breast Cancer Model

- 80% of Subjects Immunized with Anti-PS Immunocytokines and Irradiated Tumor Cells Achieved Long-Term Survival Compared to Just 20% of Controls - - Data Highlights Broad Anti-Cancer Potential of Peregrine's Anti-PS Vascular Targeting Antibodies - SAN DIEGO and TUSTIN, Cal...

Pharmacyclics Announces Preclinical Results Supporting Development of Its Novel Btk Inhibitor in Immune Mediated Diseases

SAN DIEGO and SUNNYVALE, Calif., April 14 /PRNewswire-FirstCall/ -- Pharmacyclics, Inc. (Nasdaq: PCYC ) today presented results from its preclinical program evaluating PCI-32765, an orally available, selective inhibitor of Bruton's tyrosine kinase, or Btk, in B-cell receptor (BCR) modulated d...

Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients

Data from 150 lung transplant patients demonstrates potential to improve management of risk for infection BOSTON, April 10 /PRNewswire/ -- A prospective analysis of data collected from 170 patients receiving lung transplantation at the University of Pittsburgh Medical Center...

Independent Studies Report on Possible Roles for Cylex's Immune Cell Function Assay in Monitoring of Heart and Lung Transplant Recipients

Six different studies will report on use of ImmuKnow assay in presentations at the annual meeting of the International Society for Heart and Lung Transplantation COLUMBIA, Md., April 9 /PRNewswire/ -- Since it was initially cleared as an in vitro diagnostic techniqu...

Cell Genesys Reports Association Between Immune Response and Patient Survival in Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer

SOUTH SAN FRANCISCO, Calif., Feb. 15 /PRNewswire-FirstCall/ -- Cell Genesys, Inc. (Nasdaq: CEGE ) today reports the results of an analysis examining the potential association between immune responses to GVAX immunotherapy for prostate cancer and increased patient survival in a Phase 2 trial i...

A Functional Immune System Can Be Derived From Embryonic Stem Cells, Preliminary Study Finds

WASHINGTON, Feb. 12 /PRNewswire-USNewswire/ -- A new study demonstrates for the first time that embryonic stem cells can be used to create functional immune system blood cells, a finding which is an important step in the utilization of embryonic stem cells as an alternative source of cells for...

Genetic Immunity Presents Clinical Data on DermaVir Patch Immune Therapy at 15th Annual Conference on Retroviruses and Opportunistic Infections

Data Shows Excellent Safety Profile and Long Lasting Immunity MCLEAN, Va., and BUDAPEST, Hungary, Feb. 11 /PRNewswire/ -- Genetic Immunity, a US/Hungarian clinical-stage biopharmaceutical company focusing on the development of its patented immunotherapeutic platform technology, announced ...

Rigel Announces Initiation of Phase 1 Clinical Trial of R348 for Rheumatoid Arthritis, Psoriasis and Other Immune Disorders

SOUTH SAN FRANCISCO, Calif., Jan. 9 /PRNewswire-FirstCall/ -- Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL ) announced today that it has begun enrolling patients in a Phase 1 study to evaluate the safety and tolerability of R348, an orally available, potent inhibitor of Janus Kinase 3 (JAK3), as...

Researchers Train the Immune System to Deliver Virus That Destroys Cancer in Lab Models

Procedure also could prevent recurrence ROCHESTER, Minn., Dec. 18 /PRNewswire-USNewswire/ -- An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts o...

Bristol-Myers Squibb, New Jersey Children's Hospital Launch Center for Immune System Disorders & Infectious Diseases Including HIV/AIDS

NEW BRUNSWICK, N.J., Nov. 30 /PRNewswire-FirstCall/ -- Underscoring its worldwide commitment to children with HIV/AIDS, Bristol-Myers Squibb Company (NYSE: BMY ) today joined Robert Wood Johnson University Hospital in opening a new clinical center at The Bristol-Myers Squibb Children's Hospit...

Iomai Trial Shows 100 Percent Immune Response in Elderly Subjects Vaccinated With Novel Travelers' Diarrhea Patch Vaccine

GAITHERSBURG, Md., Aug. 9 /PRNewswire-FirstCall/ -- Iomai Corporation (Nasdaq: IOMI ) today announced that interim results from a Phase 1 safety and immunogenicity trial of its patch-based vaccine for travelers' diarrhea found that all subjects who received the vaccine -- 19 elderly and 17 ad...

Inimex Product Candidate is First Immune Defense Regulator to Cure Infections Without Causing Harmful Inflammation

Novel Approach to Address Growing Problem of Antibiotic Resistance Published in Nature Biotechnology VANCOUVER, British Columbia, March 26, 2007 /PRNewswire/ -- Inimex Pharmaceuticals Inc.'s product candidate IDR-1 is the first immune system trigger to cure infections without causing harmful infla...

Novavax Vaccine Provides Robust Immune Response, Pre-Clinical Data Show

Study Published in Vaccine Shows Strong Immune Response, Protection Against H9N2 Influenza Strain ROCKVILLE, Md., April 02, 2007 /PRNewswire-FirstCall/ -- Novavax Inc.'s virus- like particle (VLP) vaccine triggered a robust immune response and provided protection against the H9N2 strain of avian i...

Data Presented at AACR Meeting Show Peregrine's Bavituximab Equivalent Can Generate Curative Immune Responses as Part of a Vaccine-Like Regimen in Preclinical Models of Aggressive Brain Cancer

--Immunization with a Bavituximab Equivalent and Irradiated Tumor Cells Increased Long-Term Survival to 57% From 0% in Controls in a Preclinical Model of Brain Cancer-- LOS ANGELES and TUSTIN, Calif., April 18, 2007 /PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. , a clinical stage bioph...

Iomai Dose-Ranging Trial Demonstrates Needle-Free Patch Vaccine for Travelers' Diarrhea Stimulates Immune Response Even at Low Doses

-- Data Gathered to Assist in Design of Future Trials, Other Programs -- GAITHERSBURG, Md. and LISBON, Portugal, April 26, 2007 /PRNewswire-FirstCall/ -- Iomai Corporation today announced results from a 400-patient, Phase 2 dose-ranging trial of its patch-based vaccine for travelers' diarrhea. The...

CEL-SCI's Cel-1000 Shown to Significantly Enhance Immune Response Against Hepatitis B Antigen in Animals

VIENNA, Va., May 01, 2007 /PRNewswire-FirstCall/ -- CEL-SCI CORPORATION announces that CEL-1000 alone increased the immune response against hepatitis B antigen, and that the combination of CEL-1000 with MAS-1, a proprietary water-in-oil adjuvant delivery system owned by Mercia Pharma, induced high...

Enzo Biochem Individualized Oral Immune Regulation Therapy May Be Effective Approach to Treating Crohn's Disease

WASHINGTON--(BUSINESS WIRE)--May 22, 2007 - Alequel(TM), an individualized oral immune regulation preparation, may be an effective treatment for moderate-to-severe Crohn's disease. Interim data from two ongoing double-blind, placebo controlled Phase II studies suggest that this investigational appr...

VGX Pharmaceuticals' Novel HIV and Pandemic Influenza DNA Vaccine Candidates Trigger Robust Immune Responses and Protection in Pre-Clinical Models

MALAGA, Spain--(BUSINESS WIRE)--May 23, 2007 - VGX Pharmaceuticals' novel pandemic influenza vaccine candidates triggered protective immune responses in pre-clinical challenge studies, according to data presented for the first time today at the Third International Conference on DNA Vaccines in Mala...

CEL-SCI'S CEL-1000 Shown to Significantly Enhance Immune Response Against Avian Flu Antigen in Animals

VIENNA, Va., May 23, 2007 /PRNewswire-FirstCall/ -- CEL-SCI CORPORATION announces that CEL-1000 increased the immune response against H5 avian influenza antigen in combination with MAS-1, a water-in-oil adjuvant delivery system. These findings were presented on May 23, 2007 by Dr. Daniel Zimmerman...

Pharmexa A/S (DK) - Long lasting immune response and survival to RAS vaccine

Summary: Follow-up RAS data presented at ASCO HORSOLM, Denmark, June 4, 2007-Professor Trond Buanes today gave a presentation titled "RAS peptide vaccination in resected pancreatic cancer patients - persistence of anti tumour response and long term survival" at ASCO's (American Society of Clinic...

Cervarix, the GSK Cervical Cancer Candidate Vaccine, Provides Sustained Immune Response in 100 Percent of Women up to 55 Years of Age

New Study Results Show Antibodies Against Cancer-Causing Virus Types 16 & 18 That Are At Least Ten Times Greater Than Natural Infection Levels CHICAGO, June 05, 2007 /PRNewswire/ -- New Phase III data show that at 18 months after the first of a three-dose regimen, 100 percent of women up to ag...

Research Indicates Geron's Human Embryonic Stem Cell-Based Therapeutic for Spinal Cord Injury Evades Direct Attack by the Human Immune System

MENLO PARK, Calif.--(BUSINESS WIRE)--Jun 11, 2007 - Geron Corporation (Nasdaq:GERN) today announced the presentation of research studies indicating that GRNOPC1, the company's human embryonic stem cell (hESC)-based therapeutic for the treatment of spinal cord injury, evades a direct attack by the h...

Tiny Cup Attached to Eye Improves Drug Delivery For Retinal Diseases

...doses of the drug are needed to achieve a therapeutic concentration in the retina. The chemotherapy destroys the bone marrow and depresses the child's immune system, often leading to secondary infections. Intravitreal injections using a syringe, often used to treat age-related macular degeneration, r...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...ollaboration with GSK, including the $500,000 discovery milestone payment that Regulus received from GSK for demonstrating a pharmacological effect in immune cells by specific microRNA inhibition. Excluding non-cash compensation expense related to stock options, operating expenses for Regulus were $2...

British Woman Celebrates a Year of Living Cancer-Free

...e other treatments I've had, which were very, very grueling." The idea behind the new treatment is this: NK cells, which are part of the body's immune system, will target and fight any leukemia cells that survive chemotherapy if they are activated to fight the cancer. In cancer patients, however, the...

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

...ccines derived from patients' own cancer cells and immune cells were well tolerated and resulted in impressi...ed with a vaccine that included each patient's own immune cells (dendritic cells) and 500 micrograms of granulocyte-colony stimulating factor (GM-CSF), an immune stimulator, three times a week and then monthly fo...

Dirucotide Does Not Meet Primary Endpoint in Phase III MAESTRO-01 Trial in Secondary Progressive Multiple Sclerosis

...ed as a statistically significant increase in the time to progression of the disease, as measured by the EDSS, in patients with HLA-DR2 and/or HLA-DR4 immune response genes. It is estimated that up to 70% of all multiple sclerosis patients are HLA-DR2 and/or HLA-DR4 positive(i). The EDSS is the standard for...

R788 in TASKi3 Clinical Trial Does Not Meet Efficacy Endpoints in RA Patients Who Had Previously Failed Biologic Therapies - Results Incongruent

...ul and potentially debilitating disease, that affects more than 2 million people in the U.S. It is a chronic inflammatory disease that puts the body's immune system into overdrive where it ultimately causes inflammation in the joints and destroys soft tissues, cartilage and bone. Rigel's R788 is a novel, o...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... rats. The rat is a widely used laboratory animal with a well characterized immune system, a nearly complete genome sequence, and established transgenesis and...cademic laboratory. Its scientific activity is centered in the analysis of immune responses and in immunointervention strategies in organ transplantation. T...

Octapharma Accepting Applications for Research Grants on Immunotherapy, Coagulation Disorders and Critical Care

...t, production and sale of high quality human protein therapies, including immune globulin intravenous (IGIV). In the U.S., Octapharma's IGIV product, oc...(immune globulin intravenous [human] 5%), is used to treat disorders of the immune system, and Octapharma's Albumin (Human) is indicated for the restorati...