IgA in Medical Technology

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

Trial to Evaluate Safety of CCL2-LPM for Inflammatory Kidney Disease SAN FRANCISCO, April 14 /PRNewswire/ -- Osprey Pharmaceuticals U.S.A., Inc. announced today that patient dosing has commenced in a Phase Ib clinical trial of the company's lead compound, CCL2-LPM, for the treatment of IgA ne...

Mymetics' HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model

NYON, Switzerland, June 07, 2007 /PRNewswire-FirstCall/ -- Mymetics Corporation announced today analysis of results demonstrating that the Company's HIV vaccine elicited neutralizing IgA mucosal antibodies in a non-human primate model. Mucosal IgA antibodies are considered as a possible first line...

Baxter Initiates Phase III Trial for the Treatment of Alzheimer's Disease

...is contraindicated in patients with known anaphylactic or severe hypersensitivity responses to Immune Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA antibodies that can result in a severe anaphylactic reaction. Immune Globulin Intravenous (Human) p...

Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced

...e Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA a...elective IgA deficiency (IgA < 0.05 g/L) where the iga deficiency is the only abnormality of concern. I...ctions or anaphylaxis in the setting of detectable iga levels following infusion of GAMMAGARD S/D. Immu...

Baxter Presents Latest Clinical Trial Results of GAMMAGARD LIQUID Administered Subcutaneously

...is contraindicated in patients with known anaphylactic or severe hypersensitivity responses to Immune Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA antibodies that can result in a severe anaphylactic reaction. Immune Globulin Intravenous (Human) p...

Cutanea Announces Promising Phase II Results in Rosacea with Omiganan

...s at Week nine and at each interim visit, the percent change in number of inflammatory lesions at interim visits, the absolute change from Baseline in iga score and other signs and symptoms of rosacea at Week nine and each interim visit, and Treatment Success at Week nine and each interim visit. Althoug...

Baxter and The Alzheimer's Disease Cooperative Study Group to Pursue a Phase III Study of Gammagard Liquid in Patients With Alzheimer's Disease

...e Globulin (Human). Patients with severe selective iga deficiency (IgA < 0.05 g/L) may develop anti-IgA a...selective IgA deficiency (IgA, 0.05 g/L) where the iga deficiency is the only abnormality of concern. Im...ctions or anaphylaxis in the setting of detectable iga levels following infusion of GAMMAGARD S/D. Immun...

Iomai Trial Shows 100 Percent Immune Response in Elderly Subjects Vaccinated With Novel Travelers' Diarrhea Patch Vaccine

...i patch, regardless of age, seroconverted with IgG antibodies. Moreover, 18 of 19 elderly subjects and 15 of 17 adult subjects also seroconverted with iga antibodies. The study was conducted in Belfast, Ireland, and subjects received two patches, 21 days apart, containing "heat labile" toxin, or LT, and ...

Mymetics' HIV Vaccine Achieves Research Breakthrough, Eliciting Protective Antibody Response in Mucosal Tissues of Non-Human Primate Model

...nced today that the Company's HIV vaccine elicited iga mucosal antibodies in a non-human primate model. Mucosal iga antibodies are considered a possible first line of...eptides from the MPR can Elicit Protective Mucosal iga in Vaccinated Macaques," at the Keystone Symposium...

Ceragenix Announces Results from Phase IV Study of EpiCeram Meet All Primary and Secondary Endpoints

... Percentage of subjects reaching clear or almost clear on IGA at Day 28 Assessment of the disease progression showed significant improvements in the iga scores over time for both EpiCeram(TM) and Cutivate(R) cream with 61.1% of the EpiCeram(TM) patients assessed as clear or almost clear after 28 days o...

Barrier Therapeutics Announces Liarozole Phase 2/3 Study Results in Lamellar Ichthyosis

...ectively. For the secondary endpoints of mean iga score at week 8 and the overall scaling score at w...cant differences from placebo (p < 0.05). The mean iga score at week 8 was reduced by 36% and 43% for the...oups, respectively versus 3% for placebo. The mean iga score for the two liarozole treatment groups conti...

Non-Invasive Diagnostic Tests for Celiac Disease

... indicate that tests for endomysial (EMA) and tissue transglutaminase (tTG) iga autoantibodies have over 95 percent sensitivity, and close to 100 percent s...esting is useful for testing pediatric populations and for individuals with iga deficiency. Anti-gliadin antibody testing can also be used to monitor pati...

West Nile Virus Screening and Diagnostics Technology Emerges In Step with North American Outbreak

...testing that includes the PRNT, which satisfies the CDC requirement for performing a WNV-specific serology test; antibody ELISAs for serum and CSF, an iga ELISA for serum, and RT-PCR to detect viral RNA in CSF or serum. PANBIO offers the West Nile Virus IgM Capture ELISA and the West Nile Virus IgG In...