Identify

NIEHS Researchers Identify Enzyme Critical in DNA Replication

BETHESDA, Md., July 5, 2007--In this weeks issue of Science,researchers from the National Institute of Environmental HealthSciences (NIEHS) and Umeö University in Sweden report animportant discovery about a critical new role that an enzyme calledDNA polymerase epsilon plays in replicating DNA in higher organismssuch as yeast and perhaps even humans. The study places us one ste...

Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression

Findings Published in Molecular Cell Show Potential of microRNAs asNovel Cancer Drug Targets REHOVOT, Israel and NORTH BRUNSWICK, New Jersey, July 05, 2007/PRNewswire-FirstCall/ -- Rosetta Genomics Ltd , a leading microRNAcompany, announced today research published in the journalMolecular Cell by scientists from the Weizmann Institute of Scienceand Rosetta Genomics . The findings suggest...

Researchers Discover Method for Identifying How Cancer Evades the Immune System

PHILADELPHIA, July 3, 2007-- One of the fundamental traits of atumor – how it avoids the immune system – might becomeits greatest vulnerability, according to researchers from theUniversity of Southern California. Their findings,demonstrated in human breast and colorectal cancers, indicate thata technique for determining a tumor’s “immunesignature,” could be...

Schepens Scientists Identify Key to Integrating Transplanted Nerve Cells Into Injured Tissue

Discovery promises to make retina, spinal cord and other centralnervous system transplants possible BOSTON, April 26, 2007 /PRNewswire/ -- Scientists at theSchepens Eye Research Institute, an affiliate of Harvard MedicalSchool, have identified a key mechanism for successfullytransplanting tissue into the adult central nervous system. Thestudy found that a molecule known as MMP-2 (which is...

Researchers Identify New Genetic Risk Factors for Type 2 Diabetes

Landmark Study Shows At Least 10 Genetic Variants Are AssociatedWith Adult Onset Diabetes BETHESDA, Md., April 26, 2007 – In the mostcomprehensive look at genetic risk factors for type 2 diabetes todate, a U.S.-Finnish team, working in close collaboration with twoother groups, has identified at least four new genetic variantsassociated with increased risk of diabetes and conf...

Preclinical Studies Identify Novel Approach for Enhancing the Anticancer Activity of Introgen's INGN 241

AUSTIN, Texas--(BUSINESS WIRE)--Apr 25, 2007 - IntrogenTherapeutics, Inc. (NASDAQ:INGN) today announced the publication ofnew preclinical data describing how an intrinsic cell survivalpathway impacts the anticancer activity of INGN 241. Inhibition ofthis pathway, known as NF-kB, enhanced the tumor killing effects ofINGN 241 in cell culture and in preclinical models of human tumors.Researche...

Researchers Identify Intracellular Pathway of Alfacell's Onconase

Paper Published in Journal of Cell Science Shows ONCONASE Uptake inCells Differs from other RNases BLOOMFIELD, N.J., April 05, 2007 /PRNewswire-FirstCall/ --Alfacell Corporation today announced that European researchers haveidentified the pathway that ONCONASE (ranpirnase) follows to entercells. Published in the Journal of Cell Science (2007; 120: 1405-1411),a paper based on studie...