Genetic in Medical Technology

Mayo Clinic Study Finds Earliest Evidence of Memory Decline in Middle-Aged People at Genetic Risk for Alzheimer's Disease

SCOTTSDALE, Ariz., July 15 /PRNewswire-USNewswire/ -- Memory lapses that occur with normal aging are a source of worry for many who fear Alzheimer's disease . Now a new Mayo Clinic-led study published in the July 16 issue of the New England Journal of Medicine suggests that the c...

deCODE Discovers Second Common Genetic Risk Factor for Atrial Fibrillation and Stroke

REYKJAVIK, Iceland, July 13 /PRNewswire-FirstCall/ -- Scientists at deCODE genetics (Nasdaq: DCGN ) and colleagues from Europe and the United States today report the discovery of a common single-letter variant in the sequence of the human genome (SNP) conferring increased risk of atrial fibr...

deCODE-led Megastudy Finds New Genetic Clues to Causes of Schizophrenia

REYKJAVIK, Iceland, July 1 /PRNewswire-FirstCall/ -- The largest study of the genetics of schizophrenia ever undertaken has revealed several new common single-letter variants in the sequence of the human genome (SNPs) linked to risk of the disease. The study, by a multinational consortium of s...

Value of Genetic Testing for Preventing Blood Clots Unproven, According to New AHRQ Study

ROCKVILLE, Md., June 16 /PRNewswire-USNewswire/ -- According to a new report by HHS' Agency for Healthcare Research and Quality, there is insufficient evidence to conclude that genetic testing for two gene mutations in adults with a history of blood clots helps to prevent a condition known as deep...

Mayo Researchers Help Discover Genetic Cause for Primary Biliary Cirrhosis

ROCHESTER, Minn., May 27 /PRNewswire-USNewswire/ -- Researchers have discovered a novel molecular path that predisposes patients to develop primary biliary cirrhosis , a disease that mainly affects women and slowly destroys their livers. Primary biliary cirrhosis has no known cause. The fi...

New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel

TOKYO and INDIANAPOLIS, Ind., May 5 /PRNewswire-FirstCall/ -- A new substudy from 1,466 patients from the Phase III TRITON-TIMI 38 clinical trial showed that patients who took prasugrel and had a reduced function of the CYP2C19 gene did not have an increased risk of cardiovascular death, heart att...

Investigational Genetic Test May Help Address Common Problems in Prostate Cancer Diagnosis

- Eight Studies Presented at Leading Urology Meeting Show that Simple Urine Test for PCA3 Gene May Improve Accuracy of Prostate Cancer Detection, Reduce Unnecessary Biopsies - - Gen-Probe to Begin Pivotal Clinical Study in Effort to Gain U.S. Regulatory Approval - SAN DIEGO, ...

Scientists Unmask Genetic Markers Associated With Psoriasis

University of Michigan scientists reveal DNA 'hotspots' linked to psoriasis ANN ARBOR, Mich., Jan. 25 /PRNewswire-USNewswire/ -- Scientists at the University of Michigan Department of Dermatology , the U-M School of Public Health and their collaborators have found DNA "hotspots" that ma...

A Milestone in Cancer Genetics: deCODE Discovers First Common Genetic Variants Affecting the Risk of Many Types of Cancer

REYKJAVIK, Iceland, Jan. 18 /PRNewswire-FirstCall/ -- Scientists at deCODE genetics (Nasdaq: DCGN ) and colleagues from the US and ten European countries today announced a long-awaited first in cancer research: the discovery of common single-letter variations in the human genome (SNPs) linke...

Landmark Research Study is Launched to Assess Impact of Personal Genetic Testing

Scripps Translational Science Institute, Navigenics, Affymetrix and Microsoft team on groundbreaking health study SAN DIEGO, Oct. 9 /PRNewswire/ -- A consortium of health care, technology and research leaders have joined forces in a first-of-its-kind research study to assess the behavioral i...

New Computer-Based Tools Will Help Make Best Use of Genetic Breast Cancer Tests

ROCKVILLE, Md., Sept. 22 /PRNewswire-USNewswire/ -- A new federal project, funded by the Agency for Healthcare Research and Quality, will lead efforts to develop, implement and evaluate four computer-based decision-support tools that will help clinicians and patients better use genetic tests to...

Interleukin Genetics and Geisinger to Collaborate on Genetic Tests to Predict Weight Loss Success

WALTHAM, Mass. and DANVILLE, Pa., Sept. 18 /PRNewswire-FirstCall/ -- Interleukin Genetics, Inc. (Amex: ILI ), and Geisinger Health System, today announced a research collaboration to explore the role of genetics in obesity. The goal of the collaboration is to develop a series of genetic tests...

Encouraging Gene Therapy Results in Genetic Form of Blindness

NEW ROCHELLE, N.Y., Sept. 8 /PRNewswire/ -- All three patients who received intraocular adeno-associated virus-based gene therapy to treat Leber congenital amaurosis (LCA), an incurable genetic disorder that results in blindness, had improved vision, according to a paper published online ahead...

Interleukin Genetics Launches Enhanced Heart Health Genetic Test Report Format

Report Includes an Individual's Genetic Risk Based on Clinical Data, Preventive Measure Guidance and Scientific Educational Materials WALTHAM, Mass., July 22 /PRNewswire-FirstCall/ -- Interleukin Genetics, Inc. (Amex: ILI ), today announced the launch of an enhanced test report format an...

June 2008 Mayo Clinic Women's HealthSource Highlights Shingles Vaccine for Pain Prevention, Tips to Avoid Antibiotic Resistant Infections, and Benefits of Broad Genetic Testing

ROCHESTER, Minn., June 24 /PRNewswire-USNewswire/ -- Here are highlights from the June issue of Mayo Clinic Women's HealthSource. You may cite this publication as often as you wish. Mayo Clinic Women's HealthSource attribution is required. Reprinting is allowed for a fee. Include the following...

Join NPR's David Ewing Duncan, Author Jessica Queller and a Panel of Medical and Legal Experts in a 90-Minute Webcast on Genetic Testing, Genomic Medicine and Breast & Ovarian Cancer

GREENWICH, Conn., May 19 /PRNewswire/ -- Helix Health, the first U.S. stand-alone genomic medicine practice, is hosting a 90-minute webcast this Wednesday, May 21, 2008 from 1:00-2:30 PM EDT examining: How Genomic Medicine Is Changing the Management of Breast & Ovarian Cancer To register...

deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer

Discoveries help to detail how some fair coloring traits contribute to risk of skin cancer; findings will be integrated into the deCODEme(TM) service REYKJAVIK, Iceland, May 18 /PRNewswire/ -- In two papers published today, deCODE scientists and academic colleagues from Europe and the U.S. expa...

Preclinical Study Shows CTI's Brostallicin's Cancer-Killing Ability Based on Genetic Profiling

Data presented at AACR 2008 SAN DIEGO, April 15 /PRNewswire-FirstCall/ -- Systems Medicine LLC (SM), a wholly owned subsidiary of Cell Therapeutics, Inc. (CTI) (Nasdaq and MTAX: CTIC), presented data from a preclinical study demonstrating that the Company's experimental d...

Navigenics'(TM) Genome Analysis Used In Research Trial on the Impact of Providing Genetic Risk Assessments

REDWOOD SHORES, Calif., April 8, 2008 /PRNewswire/ -- Navigenics, a genetic health services company, today announced a new study of genetic predisposition analysis. The Mayo Clinic study will examine how patients understand and use information provided by a Navigenics genetic risk assessment. ...

Ranolazine Shortens QT Interval and Improves Cardiac Relaxation in Study of Patients With Genetic Sodium Channel Disorder

- Clinical evidence for unique Ranexa(R) mechanism of action - CHICAGO, March 31 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX ) announced today that ranolazine significantly (p<0.001) shortened the QT interval of patients with a hereditary form of long QT syndrome called...

American Fertility Association Calls for Expanded Research to Advance New Technology to Screen Embryos for Genetic Abnormalities

Research presented this week at American Society for Reproductive Medicine meeting could significantly improve ability to identify embryos that present high risk of birth defects or miscarriage for IVF patients AFA supports efforts to bring advanced screening technology to patients as quickly...

Preimplantation Genetic Diagnosis International Society Refutes American Society of Reproductive Medicine Opinion - States Preimplantation Genetic Screening is Beneficial When Performed in Experienced Centers

CHICAGO, Oct. 16 /PRNewswire/ -- The Preimplantation Genetic Diagnosis International Society (PGDIS) is releasing a statement in response to a Practice Committee Opinion issued today by the American Society for Reproductive Medicine (ASRM). The rationale for determining chromosomal status in ...

deCODE Launches deCODE MI(TM) -- A Test for a Major Genetic Risk Factor for Early-onset Heart Attack

REYKJAVIK, Iceland, Oct. 11 /PRNewswire-FirstCall/ -- deCODE genetics (Nasdaq: DCGN ) today announced the launch of deCODE MI(TM), a reference laboratory test for variations in the genome (called SNPs) that the company has associated with increased risk of myocardial infarction, or heart atta...

454 Sequencing(TM) in Science Today: Researchers Uncover a Genetic Basis for Different Social Behaviors in Wasps

BRANFORD, Conn. Sept. 27 /PRNewswire/ -- 454 Life Sciences, a Roche company, in collaboration with researchers from the University of Illinois at Urbana-Champaign today announced that they have uncovered genetic underpinnings to social behavior in wasps. Using the company's Genome Sequencer(TM...

Targeting Specific Mutations Reveals Promising New Approach to Treating Genetic Disorders; Preclinical Data Published in Nature

PTC124 Targets Nonsense Mutations; Addresses Underlying Cause of Genetic Disorders and Restores Protein Function SOUTH PLAINFIELD, N.J., April 23, 2007 /PRNewswire/ -- New preclinical data published online in the current edition of the journal Nature show that PTC124, an investigational new drug d...

Researchers Identify New Genetic Risk Factors for Type 2 Diabetes

Landmark Study Shows At Least 10 Genetic Variants Are Associated With Adult Onset Diabetes BETHESDA, Md., April 26, 2007 – In the most comprehensive look at genetic risk factors for type 2 diabetes to date, a U.S.-Finnish team, working in close collaboration with two other groups, has iden...

ARUP Laboratories Applauds FDA's Decision on the Value of KRAS-Mutation Testing in Colorectal Cancer

...han 2,600 employees, ARUP offers in excess of 2,000 tests and test combinations, ranging from routine screening tests to highly esoteric molecular and genetic assays, for patients nationwide. Rather than competing with its clients for physician office business, ARUP chooses instead to support clients' existi...

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

...e," said Sylvie Gregoire, President of Shire Human genetic Therapies. "This data are consistent with those pr...urological involvement. It is also the most common genetic disease affecting Ashkenazi Jewish people (Eastern...pecific enzyme deficiency in the body, caused by a genetic mutation received from both parents. The disease c...

Diabetes Gene Raises Odds of Lower Birth Weight

...n to be involved in the development of type 2 diabetes also predisposes children to having a lower birth weight. The finding sheds light on a possible genetic influence on how prenatal events may set the stage for developing diabetes in later childhood or adulthood. Researchers from The Children's Hos...

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

...uses its business on attention deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal (GI) diseases as well as opportunities...g and commercialization of the Company's Specialty Pharmaceutical and Human genetic Therapies products, as well as the ability to secure and integrate new prod...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... also carried the modifications, demonstrating the genetic changes were permanent and heritable. Together, t...l subjects for modeling human diseases. Extensive genetic characterization has revealed that approximately 9...pplication that has the potential to revolutionize genetic engineering of animals." "We have investe...

National Cancer Institute Research Identifies Unique Mechanism of Brostallicin's Anti-Tumor Effectiveness

...cal, clinical, and regulatory expertise to find and exploit a specific cancer's 'context of vulnerability.' Specifically, SM defines the molecular and genetic alterations (context) that cause cancer cells to be particularly sensitive (vulnerable) to a drug or combination of drugs--the "context of vulnerabili...

Shire Receives Fast Track Designation for velaglucerase alfa for Gaucher Disease

...urological involvement. It is also the most common genetic disease affecting Ashkenazi Jewish people (Eastern...pecific enzyme deficiency in the body, caused by a genetic mutation received from both parents. The disease c...ntion deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal (GI) diseases...

Results From Drug Trials and New Risk Factors Announced at International Alzheimer's Conference

...l incentives for participation in research. The researchers found that large percentages of African Americans are willing participants for Alzheimer's genetic studies, if culturally sensitive techniques are used to recruit them. Recruiting participants for clinical studies is the second greatest bar...

University of Michigan Study Shows SEQUENOM's MassARRAY Technology Identifies HPV Infections Missed by Standard Hybridization Test

...ctrometry-based nucleic acid analysis platform that quantitatively measures genetic target material and its variations in a rapid, accurate, and cost efficient...OM SEQUENOM is a life sciences company committed to providing the best genetic analysis products that translate the results of genomic science into soluti...

Sirius Genomics Announces New Collaboration with Assistance Publique-Hopitaux de Paris

...ith clinical outcomes, leading to proprietary and commercially viable PGx products that enable better drug treatment. The Company's first product is a genetic predictor of response to treatment for sepsis, a severe blood infection. This release contains forward-looking statements that are not based on h...

Results From Trials of DHA in Alzheimer's Disease and Age-Related Cognitive Decline

...this study - and other recent Alzheimer's and mild cognitive impairment therapy trials - concerns a possible interaction between certain therapies and genetic status. This issue needs to be explored more completely in future trials," Thies added. Memory Improvement with DHA Study (MIDAS) Re...

Why Do African-Americans Fare Worse With Cancer? Access and Economics Are Only Part of the Story

...nomic factors are controlled for. The finding points to biological or host genetic factors as the potential source of the survival gap. "When you look at...sity College of Physicians and Surgeons . "There may be differences in genetic factors by race that alter the metabolism of chemotherapy drugs or that mak...

Shire has Filed a Treatment Protocol for Velaglucerase Alfa for Gaucher Disease

...urological involvement. It is also the most common genetic disease affecting Ashkenazi Jewish people (Eastern...pecific enzyme deficiency in the body, caused by a genetic mutation received from both parents. The disease c...ntion deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal (GI) diseases...

More Gene Mutations Linked to Autism Risk

... --Combination of Inherited and New genetic Mutations Acting Together-- PHILADELPHIA, Jun...g institutions. This study identified 27 different genetic regions where rare copy number variations - missin...lthy controls. The complex combination of multiple genetic duplications and deletions is thought to interfere...