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MitraClip(R) Therapy Data Shows Important Clinical Benefit in High Risk Patients With Functional Mitral Regurgitation at 12-Month Follow Up

EVEREST High-Risk Registry Data Shows Improved Symptomatic Status and Cardiac Function in Functional MR Patients Treated with the MitraClip(R) System ORLANDO, Fla., March 28 /PRNewswire/ -- Percutaneous mitral valve repair using the MitraClip(R) system in symptomatic high-risk surgical patien...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

SAN FRANCISCO, Dec. 8 /PRNewswire-FirstCall/ -- Amgen Inc. (Nasdaq: AMGN ) today released updated results from the ongoing, open-label extension study of the long-term safety and efficacy of Nplate(TM) (romiplostim) in adult patients with chronic immune thrombocytopenic purpura (ITP). Chronic IT...

Tibotec Data Presented at ICAAC and HIV9 Follow Key Regulatory Approvals for Anti-HIV Compounds

- Not Intended for Journalists in the UK or Ireland - New Findings From ARTEMIS and TITAN Studies Demonstrate Growth of the Tibotec Virology Franchise GLASGOW, Scotland, Nov. 12 /PRNewswire/ -- New data on PREZISTA(R) (darunavir), a protease inhibitor from Tib...

Second Successful Quigley QR-443 Study Suggests Method of Action Relevant to Broad Range of Chronic Inflammatory Diseases - Human Study to Follow -

DOYLESTOWN, Pa., June 20, 2007 /PRNewswire-FirstCall/ -- Quigley Pharma, www.QuigleyPharma.com , a wholly owned subsidiary of The Quigley Corporation announced today that it has completed a follow-up study to evaluate the impact of QR-443 on...

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

...RAS status and secondary endpoints include overall survival, objective response rate, time to progression, duration of response and safety. Long-term follow up for overall survival is ongoing. About KRAS Results from studies performed over the last twenty-five years indicate that KRAS pla...

Nektar Therapeutics Reports Second Quarter 2009 Financial Results

...e call beginning at 5:00 p.m. Eastern Time (ET)/2:00 p.m. Pacific Time (PT) on Tuesday, August 4, 2009. To access the conference call, follow these instructions: Dial: (866) 831-6270 (U.S.); (617) 213-8858 (international) Passcode: 25099763 (Howard Robin is the host) ...

Project Zero Delay Accelerates Drug's Path to Clinical Trial

...are in "America's Best Hospitals," a survey published annually in U.S. News & World Report. Get M. D. Anderson News Via RSS follow M. D. Anderson News on Twitter About AstraZeneca AstraZeneca is a major international healthcare business engaged in the research, develo...

FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia

...y the European Medicines Agency (EMEA) for the treatment of schizophrenia and manic episodes associated with bipolar I disorder. The application will follow the Centralized Procedure. Schering-Plough acquired asenapine in November 2007 through its acquisition of Organon BioSciences, which developed ...

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

...itor cells that can create new depots of cancer throughout the body. Data showed that the projected five-year survival rate is 54% at a median follow up of 4.5 years (range 2.4 to 7.4) for the 30 surviving patients. Although not a direct comparison, the results are superior to those observed followi...

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

...n growth velocity when administered to pediatric patients. The long-term effect on final adult height is unknown. Health care providers should closely follow the growth of children and adolescents taking corticosteroids by any route, and reduce each patient's dose to the lowest dose that effectively control...

Cardica Announces Publication of Pivotal PAS-Port(R) Proximal Anastomosis System Clinical Trial Results

...e angiograms. The data published show that the PAS-Port system met the primary efficacy endpoint of non-inferiority in patency at nine-month follow up compared to hand-sewn anastomoses. In addition, of the 12 major adverse cardiac events (MACEs) reported that may possibly be related to target vess...

Reliv International's GlucAffect(TM) Proven Effective in Clinical Study

...consumed GlucAffect or a placebo product four times a day for six days a week, participated in an exercise program and ate a healthy diet. They didn't follow the study regimen on the seventh day of the week. "GlucAffect is formulated with a unique combination of innovative ingredients selected to m...

PTSD Associated With Higher Alzheimer's/Dementia Risk; Moderate Alcohol Consumption May Lower it

...ic brain injury, substance abuse or depression. "It is critical to follow patients with PTSD, and evaluate them early for dementia," Yaffe said. "Fur...were thoroughly evaluated. There were 523 news cases of dementia during the follow up period of the study. After adjustment for demographics, smoking...

ASMANEX(R) (Mometasone Furoate Dry Powder Inhaler) Now Approved in Japan for the Treatment of Bronchial Asthma in Adult Patients

...n growth velocity when administered to pediatric patients. The long-term effect on final adult height is unknown. Health care providers should closely follow the growth of children and adolescents taking corticosteroids by any route, and reduce each patient's dose to the lowest dose that effectively control...

deCODE-led Megastudy Finds New Genetic Clues to Causes of Schizophrenia

...ical Center, the University of Verona, the Duke University Center for Population Genomics and Pharmacogenetics and the University of Sichuan, China. follow up cohorts included those from Aarhus University, the National Serum Institute, and Bispebjerg and Glostrup hospitals, Denmark; Semmelweis University,...

Commonwealth Fund Case Study Points to 'Continuous Innovation' at Group Health Cooperative

...on, and a nationally recognized research center. Please visit the virtual newsroom on our Web site, www.ghc.org under "Newsroom." follow us on Twitter , Facebook and YouTube ...

Spherix Announces Positive Phase 2 Study Results

...HbA1c level at screening and baseline between 6.6% and 9.0%. The baseline visit followed an 8-week run-in period in which patients were instructed to follow a weight-maintaining diet and a daily exercise program under the supervision of the investigator. The run-in period was designed to compensate for th...

Cardiogenesis Announces Presentation of its PHOENIX(R) Combination TMR Plus Stem Cell Delivery System at the International Society of Minimally Invasive Cardiothoracic Surgeons (ISMICS) Annual Meeting

...l methods. Eight patients treated with the PHOENIX System completed 1 year follow up: Seven patients had concomitant coronary bypass graft...outside the U.S. It is not currently FDA approved. The abstract " One Year follow up of Combined Autologous Bone Marrow Derived Progenitor Cell Therapy and T...

Long Term Data Presented at EuroPCR 2009 from Randomized Study Attest to Durability of Results of OrbusNeich's Genous(TM) Bio-engineered R stent(TM) Compared to Drug-Eluting Stents

...swire/ -- OrbusNeich announced today that two year follow up data from a single center, randomized clinical ...the Academic Medical Center in Amsterdam, two year follow up data from the single center TRIAS HR (high risk...23 mm) and/or chronic total occlusions. Two year follow up was obtained in all patients, with the exceptio...

BioVex to Report Phase I/II Clinical Trial Results for the Front Line Treatment of Head and Neck Cancer With OncoVEX GM-CSF at the 2009 American Society of Clinical Oncology Meeting

...ed at surgery, with five patients achieving a complete response after only 2 or 3 viral doses. No patient has recurred locally in the neck at a median follow up of 26 months at the time of abstract submission. Three patients had distant metastatic disease. Two of these were in the low dose group. One additi...

Spherix Reports First Quarter 2009 Earnings

...es that occur after the date of this release or to reflect the occurrence of unanticipated events. - Tables follow - Spherix Incorporated Consolidated Statements of Operations For the Quart...

TYRX Presents Early Clinical Results from AIGISRX(TM) Antibacterial Envelope Retrospective Registry

...e AIGIS Retrospective Registry, we have begun the process of recruiting approximately 20 clinical sites for the AIGIS Prospective Registry, which will follow AIGIS patients for 12 months and compare the incidence of infection to published historical and case-matched controls of cardiac rhythm management dev...

Quest Diagnostics Introduces First Commercial Laboratory Test for Identifying the H1N1 Swine Flu Virus

...cal director, Focus Diagnostics. "We will continue to aid our public health colleagues in responding to the H1N1 outbreak, and encourage clinicians to follow testing guidelines provided by public health authorities." Focus Diagnostics has collaborated with the U.S. Centers for Disease Control and Preve...

Results From Phase 3 EQUATE Trial of VIVUS' Qnexa Highlighted at European Congress on Obesity

...-release topiramate constituents, or placebo. Patients had a four-week dose titration period followed by 24 weeks of treatment. Subjects were asked to follow a hypocaloric diet representing a 500-calorie/day deficit and advised to implement a simple lifestyle modification program. About Obesity ...

InspireMD Announces the Enrollment of the 1st Patient in the MGuard iMOS Registry, the Registry Will Enroll 1000 Patients

...g the procedure by preventing defragmentation of the thrombus. I look forward to seeing good clinical results for both the one-month and the six-month follow periods." Mr. Eli Bar CTO and VP R&D stated: "The iMOS registry is very important for us in order to understand the clinical performance of...

Program Improves Language Skills in Deaf, Hard of Hearing

...he age of three to determine the level of their language skills. "It is important for pediatricians and family physicians to ensure that families follow up on initial screenings that indicate a possible problem with a more thorough evaluation," says Susan Wiley, MD, a developmental pediatrician at Cinc...

ARVO, AOS: Large Study of Lacrisert(R) Dry Eye Insert;

...f quality of life. Patients were trained on the proper insertion and use of the insert. Patients were contacted by telephone on Day 3 of the study for follow up and reinstruction. At visit 2 (Week 4), patients were given a clinical evaluation and required to complete a second evaluation. Answers provided on...

New Studies on Once-Daily Extended Release Pramipexole Presented at American Academy of Neurology Annual Meeting

...f +1.5 points (or 35.7 percent). *The Unified Parkinson's Disease Rating Scale (UPDRS) is a comprehensive tool, which was developed to follow the longitudinal course of PD-related disability and impairment. The UPDRS II+ III score was used as the primary efficacy endpoint in both trials. ...

Men Treated for Localized Prostate Cancer Could Benefit From Pomegranate Juice Consumption

...n at LDean@AUAnet.org " target="_new"> LDean@AUAnet.org . Pantuck, A; Zomorodian, N; Rettig, M; Aronson, W; Heber, D; Belldegrun, A. Long term follow up of phase 2 study of pomegranate juice for men with prostate cancer shows durable prolongation of PSA doubling time. J Urol, suppl. 2009: 181, 4, ab...

Human Genome Sciences Reports Positive Late-Breaker Results at EASL from ACHIEVE Phase 3 Trials of Albuferon(R) in Patients with Chronic Hepatitis C

...had their dose reduced to 900-mcg albinterferon alfa-2b every two weeks. Following the dose modification, both ACHIEVE 1 and ACHIEVE 2/3 continued to follow all patients randomized on an intention-to-treat (ITT) basis according to their original dose assignment. The primary data analysis in both studies c...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...to a contemporaneous control of PEGINTRON, full-dose REBETOL and boceprevir for 48 weeks. The primary endpoint of the study was SVR after 24 weeks of follow up. In the study, the 28-week and 48-week boceprevir no lead-in arms had SVR rates of 54 percent (n=58/107) and 67 percent (n=69/103), respectively. ...

Pistachios Offer Protective Benefits Against Heart Disease, Type II Diabetes and Obesity

...c differences, when given as part of a calorie-controlled, three-month weight loss diet. The researchers randomly assigned overweight adults to follow a diet that cut calories by 500 per day from usual calorie intake. The new diet added in either an afternoon snack of 2 ounces of unsalted pretzels (...

Study Data Show Positive European Experience With DuraHeart Left Ventricular Assist Device for Advanced Stage Heart Failure Patients

...he risk of bleeding complication rose with age, with a likely cause being excessive anticoagulation/anti-platelet regimen. The investigators agreed to follow a less intensive aniticoagulation/anti-platelet regimen, which resulted in significantly improved results (neurological dysfunction: 0.23 per patient-...

Pharmos Issues Business Update on Dextofisopam Trial and Financing

...r the trial, the trial will be closed. The Company expects the final trial size to be about 320 patients. The treatment period is 12 weeks with a follow up after 4 weeks. The Company expects top line clinical data to be available by the middle of September 2009. Additional Financing secured Th...

SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease

...of treatment. Long-term results will be essential to providing more definitive guidelines for treating these complex coronary patients, and five-year follow up is planned for all patients in the SYNTAX trial." "Previously published SYNTAX data showed no difference in safety and efficacy outcomes betw...

Medgenics' Phase I/II Clinical Trial Now Shows EPODURE Continuous Anemia Treatment Lasting 5 Months in Kidney Disease Patients

...l and/or medical device companies, starting with EPODURE and INFRADURE. Medgenics plans to raise the requisite funds during 2009 to enable it to follow the current trial of EPODURE with a Phase IIb clinical trial in the US starting in 2010, and in addition, to commence a Phase I/II trial of INFRADURE ...

Worldwide Cost Estimate for Alzheimer's and Dementia Is US$315.4 Billion

...e attendees on the development and validation of biomarkers (a) to support the clinical diagnosis of Alzheimer's and dementia and (b) as indicators to follow treatment effects for disease modifying drugs. 24th Conference of Alzheimer's Disease International The 24th Conference of Alzheimer's Diseas...

PSA Screening Cuts Deaths by 20%, Says World's Largest Prostate Cancer Study

... Urology Congress in Stockholm, Sweden (17 - 21 March 2009). By initially screening men 55 to 69 years with the PSA marker and offering regular follow up, this led to an increase in early detection. Deaths due to metastasized disease were then reduced. Exact data showed that on average for every 1,40...

DURECT Reports Positive Phase IIb Data from TRANSDU(TM)-Sufentanil Clinical Program

... As a result of that meeting, we believe we understand the anticipated regulatory pathway for the Phase III program and approval, which we expect will follow a 505(b)2 pathway as discussed with FDA. (Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO ) "In this trial, all of the primary ...

The Lancet Publishes Two-Year Results of Abbott's Fully Bioabsorbable Drug Eluting Stent

...ated the following key results: A zero percent rate of stent thrombosis (blood clot formation) for all patients out to two years of follow up. No new major adverse cardiac events (MACE) between six months and two years. At two years, the bioabsorbable device demonstrated a MACE ra...