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Depression in Medical Technology

Cyberonics Provides Update on Depression Post-Approval Study

HOUSTON, July 24 /PRNewswire-FirstCall/ -- Cyberonics, Inc. (Nasdaq: CYBX ) today announced that the U.S. Food and Drug Administration ("FDA") has approved the company's proposal to amend the protocol of its D-21 post-approval dosing study in depression patients treated with ...

Ridge Diagnostics, Inc. Clinical Data on Blood Test for Depression Presented at American Psychiatric Association Annual Meeting

SAN DIEGO, May 20 /PRNewswire/ -- Ridge Diagnostics, Inc., a neurodiagnostic company, announced that data from clinical studies for its first-in-class, proprietary blood test for Major Depressive Disorder(MDD), will be presented during a poster session entitled Multianalyte Biomarker Blood Test...

Study Suggests New Treatment Approach May be Needed for Management of Depression in Some People With Bipolar Disorder

ROCHESTER, Minn., Feb. 11 /PRNewswire-USNewswire/ -- In a study published in The American Journal of Psychiatry , a team of researchers led by Mayo Clinic psychiatrist Mark Frye, M.D., attempted to identify what factors make some people with bipolar depression more likely to experience treatment-...

American Lung Association Study Finds No Evidence of Depression or Suicide Linked to Asthma and Allergy Drug Montelukast

WASHINGTON, Sept. 1 /PRNewswire-USNewswire/ -- There has been recent concern that suicide may be a complication of montelukast (Singulair) therapy. Montelukast is a Food and Drug Administration (FDA) approved oral drug that has been prescribed for more than a decade for the treatment of asthma...

HealthMedia and Aetna to Study Online Insomnia and Depression Interventions

Controlled Trial Conducted with Pilot Programs ANN ARBOR, Mich., June 19 /PRNewswire/ -- HealthMedia, Inc., the global leader in scalable behavior change interventions with outcomes, announced a new research study with Aetna which will provide HealthMedia's Overcoming(TM) Insomnia...

Study Demonstrates Lexapro(R) Significantly Improves Depression Symptoms in Adolescents

Phase III Data Presented at American Psychiatric Association Annual Meeting WASHINGTON, May 7 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX ) announced today that study results show Lexapro (escitalopram oxalate) significantly improved symptoms of depression as compared to plac...

BrainCells Inc. Initiates Phase 2 Clinical Trial with BCI-540 for Depression with Anxiety

SAN DIEGO, April 17 /PRNewswire/ -- BrainCells Inc. (BCI), a biopharmaceutical company utilizing its platform technology to identify and develop compounds that promote the growth of new neurons for the treatment of central nervous system (CNS) diseases, announced today that it has initiated a ...

Kaiser Permanente - Group Health Study Shows Depression Worsens HIV Treatment

OAKLAND, Calif., Dec. 20 /PRNewswire/ -- The largest study to examine the effect of depression on HIV treatment found that depression significantly worsens a patient's adherence to highly active antiretroviral therapy and clinical measures, but that effective antidepressant medication can reve...

Treating Depression Prolongs Life for Older People with Diabetes

Also This Month: Lessons Learned from the Avandia Controversy ALEXANDRIA, Va., Nov. 27 /PRNewswire-USNewswire/ -- Depressed, older adults with diabetes live longer when they are treated for depression, according to a study in the December issue of Diabetes Care, which publishes on November...

Lilly Receives NCQA Design Certification for Depression Care Management Program

INDIANAPOLIS, Nov. 6 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY ) has received Program Design Certification from the National Committee for Quality Assurance (NCQA) for its Tools that Empower(TM) Depression Care Management Program. Tools that Empower(TM) Depression Care Manag...

Unlikely Treatment Identified by BrainCells Neurogenesis Platform Improved Clinical Outcomes in Patients Suffering From Depression

SAN DIEGO, July 27 /PRNewswire/ -- BrainCells Inc., a company leading the scientific research of neurogenesis using its proprietary platform technology to identify novel pathways for the treatment of central nervous system (CNS) diseases, announced today results from the first cli...

Cephalon Announces Positive Results From a Phase Two Study of NUVIGIL in Bipolar Depression

Company Plans to Advance to Phase Three Trials FRAZER, Pa., March 17 /PRNewswire-FirstCall/ -- Cephalon, Inc . (Nasdaq: CEPH ) today announced positive results from a phase two clinical trial of NUVIGIL(R) (armodafinil) Tablets [C-IV] as adjunctive therapy for treating major depressive di...

VAI Finding Could Lead to New Drugs for Anxiety, Depression

Researchers determine molecular structure of promising drug target using new method GRAND RAPIDS, Mich., Oct. 15 /PRNewswire/ -- Researchers in the Laboratory of Structural Sciences at Van Andel Institute (VAI) have determined how the hormone corticotrophin releas...

American Heart Association Scientific Statement: Heart Patients Should Be Screened, Treated for Depression

Studies show that depression is about three times more common in patients following a heart attack than in the general community. Heart patients should be screened for depression, and treated if necessary. DALLAS, Sept. 30 /PRNewswire-USNewswire/ -- Heart patients should be screened for de...

NARSAD Researchers Identify Specific Genes and Family Traits Linked to Schizophrenia, Bipolar Disorder and Depression

Free, Public Event Provides Findings That Include Important Clues Toward the Development of Customized Treatment GREAT NECK, N.Y., May 30 /PRNewswire-USNewswire/ -- New findings from research supported by NARSAD, the world's leading charity dedicated to mental health research, and conducted ...

AstraZeneca Submits sNDAs for SEROQUEL XR(TM) for the Treatment of Bipolar Mania and Bipolar Depression

WILMINGTON, Del., Jan. 2 /PRNewswire-FirstCall/ -- AstraZeneca (NYSE: AZN) today announced that the company has submitted two separate supplemental New Drug Applications (sNDAs) to the U.S. Food and Drug Administration (FDA) for once-daily SEROQUEL XR(TM) (quetiapine fumarate) Extended-Release...

Forest Laboratories, Inc. Announces Positive Results of LEXAPRO(R) Phase III Study in Adolescents With Major Depression

NEW YORK, Nov. 29 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX ) and H. Lundbeck A/S today announced preliminary top-line results from a phase III study of LEXAPRO (escitalopram oxalate) in the treatment of adolescents, aged 12-17, with Major Depressive Disorder (MDD). These...

Penn Research Shows Transcranial Magnetic Stimulation Effective in Treating Major Depression

Non-drug, non-invasive treatment helps patients who have tried other options without success PHILADELPHIA, Nov. 26 /PRNewswire-USNewswire/ -- Researchers at the University of Pennsylvania School of Medicine and other study sites have found that transcranial magnetic stimulation (TMS) --...

SPRI Clinical Trials Now Enrolling Patients for Study of New Treatment for Depression

Patient Recruitment Starting Now -- For More Information, Call 888-345-7774 or Visit Our Website at http://www.spristudy.com NEW YORK, Oct. 15 /PRNewswire/ -- SPRI Clinical Trials announced today that it is now screening patients for enrollment in the parAGOn Clinical Trial Progr...

New Data Suggest Cymbalta(R) Reduced Pain in Fibromyalgia Patients With and Without Depression

INDIANAPOLIS, Aug. 21 /PRNewswire-FirstCall/ -- New data suggest that patients with fibromyalgia treated with 60mg or 120mg of Cymbalta(R) (duloxetine HCl) experienced greater reduction in pain severity beginning one week after starting duloxetine than those taking placebo (sugar pill), as mea...

New Study Supports Efficacy of Vagus Nerve Stimulation for Treatment-Resistant Depression

Mark S. George, M.D. Named Editor-in-Chief of New Brain Stimulation Journal CHARLESTON, S.C., Aug. 20 /PRNewswire/ -- Medical University of South Carolina (MUSC) today announced the results of a functional MRI (fMRI) study examining the effects of VNS (Vagus Nerve Stimulation) Therapy(TM) for pa...

Corcept Therapeutics Announces Phase 3 Study Evaluating Corlux for Psychotic Major Depression Misses Primary Endpoint

STATISTICALLY SIGNIFICANT CORRELATION BETWEEN PLASMA LEVELS AND CLINICAL OUTCOME ACHIEVED DURING TREATMENT Management will host a conference call and live webcast on March 20, 2007 at 9:00 a.m. EDT MENLO PARK, Calif. (March 19, 2007) – Corcept Therapeutics Incorporated (NASDAQ: CORT), to...

Cipralex demonstrates superiority to duloxetine for acute treatment of depression in new study

COPENHAGEN, June 4, 2007-A new study published today in the journal Current Medical Research and Opinion showed that Cipralex® (escitalopram) was superior to Cymbalta® (duloxetine) in the acute treatment of patients with major depressive disorder (MDD) and was at least as efficacious in lo...

Stanford Researchers Find Brain Pathway of Depression in Rats

STANFORD, Calif.--(BUSINESS WIRE)--Jul 5, 2007 - Scientists' hunt for the cause of depression has implicated so many suspects and found so many treatments with different mechanisms that the condition remains an enigma. Now researchers at the Stanford University School of Medicine have identified on...

In New Study, Duloxetine Reduced Non-specific Pain and Emotional Symptoms Associated with Depression

MADRID, Spain, 19 march 2007 - The antidepressant duloxetine, at a once-daily dose of 60 mg, significantly reduced non-specific pain and emotional symptoms associated with depression in a new, eight-week, placebo-controlled study of 327 adult patients with at least moderate pain and major depressi...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

SAN DIEGO, California, 23 May 2007 - The antidepressant duloxetine hydrochloride was equally effective in reducing painful symptoms in depressed patients who did not respond, or responded only partially, to treatment with a selective serotonin reuptake inhibitor (SSRI), regardless of whether those ...

Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression

COPENHAGEN, Denmark, June 04, 2007 /PRNewswire/ -- - Cipralex Better Tolerated and at Least as Effective in Long-Term Treatment H. Lundbeck A/S announces new study data published today in the journal Current Medical Research and Opinion, demonstrating that Cipralex(R) (escitalopram) was superi...

Labopharm files New Drug Submission with Health Canada for novel antidepressant

...ompare the change in the Hamilton Rating Scale for depression (HAMD-17) total score from baseline to the end of ...ions Severity (CGI-S) scale, the Montgomery Asberg depression Rating Scale (MADRS) total score and a Responder's...s study is comparable to drop out rates in typical depression studies. The results of this study are found in th...

FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia

...ssion) is a chronic, episodic illness characterized by mania (episodes of elevated moods, extreme irritability, decreased sleep and increased energy), depression (overwhelming feelings of sadness, suicidal thoughts), or a combination of both. It is the sixth leading cause of disability in the world, affecting ...

July 2009 Mayo Clinic Health Letter Highlights a Positive Outlook, Bell's Palsy and Heart Valve Repair

..., 800-333-9037, extension 9771. An ever-expanding body of research indicates that a positive outlook may improve health, decrease the risk of depression and increase longevity. The July issue of Mayo Clinic Health Letter highlights some studies and their findings. In a Mayo Clinic study, mo...

New Research Shows: Neurofeedback is an 'Evidence-Based' Treatment for ADHD

... and diagnostics of Brain related disorders. Furthermore, Brainclinics is specialized in innovative new - evidence-based - treatments such as rTMS for depression and Neurofeedback for the treatment of ADHD. Employing applied Brain research Brainclinics strives to improve and personalize treatments in order to a...

Mayo Clinic Proceedings: A Comprehensive Review of Addiction to Prescription Painkillers Among Patients and Physicians

... and gastrointestinal tract; decrease perception of pain and reaction to pain; and increase pain tolerance. Side effects include sedation, respiratory depression and constipation. When opioid consumption is ongoing, physical dependence can and will develop. This, in turn, can lead to problematic withdrawal upon...

Mayo Clinic Proceedings Reviews Deep Brain Stimulation to Treat Psychiatric Diseases

...thors. "Early results indicate the effect on depression and obsessive compulsive disorder is beneficial, b...pain receptors. In the developed world, major depression is second only to cardiovascular disease in premat...ing to the review. In persons aged 15 to 44 years, depression is the most disabling medical illness in the Unite...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

...ng, energy/fatigue, medication effects and social function(8). Improvement in depressive symptoms was also measured using the Montgomery Asberg depression Rating Scale (MADRS). During long-term, open-label therapy, ESL demonstrated a statistically significant improvement from baseline in the overall MADR...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

...nly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the potential to induce respiratory depression and neuropsychiatric events. Sodium oxybate has not been evaluated by regulators for the treatment of fibromyalgia and is not approved for this use. ...

CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders

...idase, or RIMA, is in Phase II development for the treatment of major depressive disorder. RIMAs may have efficacy advantages over current agents for depression and are expected to have a good safety profile. The company's CNS pipeline also includes CXB909, a small molecule, orally active agent for the preven...

Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

...nly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the potential to induce respiratory depression and neuropsychiatric events. Sodium oxybate has not been evaluated by regulators for the treatment of fibromyalgia and is not approved for this use. A...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

...der include long periods of euphoria, restlessness, behaving impulsively and being easily distracted(2). A mixed bipolar state occurs when symptoms of depression and mania are experienced at the same time(3). In addition to the two placebo-controlled studies, the Committee reviewed extensive Zyprexa safety...

Arena Pharmaceuticals Announces Lorcaserin Data Demonstrating Highly Significant Categorical and Absolute Weight Loss and Improvements in Secondary Endpoints Associated with Cardiovascular Risk

...sk. Lorcaserin did not result in increased risk of depression and was not associated with the development of car...ported that lorcaserin demonstrated no increase in depression or suicidal ideation compared to placebo. depression adverse events were measured using a Standard MedD...

Study Demonstrating Lurasidone Is Effective in Patients With Schizophrenia Published in The Journal of Clinical Psychiatry

... -0.2; p=0.007) scores. Lurasidone significantly improved depressive symptoms associated with schizophrenia, as measured by the Montgomery-Asberg depression Rating Scale (MADRS) at the study endpoint. The mean changes in MADRS score were -2.9 vs. -0.1 (p=0.019) for lurasidone and placebo, respectively. ...
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