Researchers Discover Method for Identifying How Cancer Evades the
Immune System
PHILADELPHIA, July 3, 2007-- One of the fundamental traits of atumor – how it avoids the immune system – might becomeits greatest vulnerability, according to researchers from theUniversity of Southern California. Their findings,demonstrated in human breast and colorectal cancers, indicate thata technique for determining a tumor’s “immunesignature,” could be...
Major New Review Supports the Broader Potential of CeNeS COMT
Inhibitor Discovery Programme
CAMBRIDGE, U.K. 2nd July 2007 - CeNeS Pharmaceuticals (AIM:CEN)("CeNeS" or "the Company") the Cambridge-based biopharmaceuticalcompany today announced that a paper published this week in CNSDrugs(1) further supports the hypothesis that acatechol-O-methyltransferase (COMT) inhibitor that acts in thebrain would be a useful agent to address profound cognitivedeficits in schizophrenia and bi...
Researchers Discover Gene For Rare Skin Disorder
WASHINGTON, June 20, 2007-Researchers funded in part by theNational Institutes of Health have identified the gene thataccounts for most cases of Goltz syndrome, a rare skin disorderthat can also affect bone and eye development. The cases appear to result from a defect in the gene known asPORCN, which contains the information needed to make a protein,referred to by researchers as porcupine...
Organon's Sugammadex Demonstrated a 9-12 Times Faster Recovery in
Phase III Pivotal Trial as Compared to Neostigmine
OSS, The Netherlands, June 11, 2007 /PRNewswire/ -- Sugammadex -the novel selective relaxant binding agent (SRBA) being developedby Organon, the human healthcare business unit of Akzo Nobel -demonstrated in a Phase III pivotal trial a 9-12 times fasterreversal of neuromuscular blockade as compared to neostigmine,without evidence of post operative residual curarization (PORC) orre-occurre...
NCI Researchers Discover Genes That Are Turned on at High Levels in
Tumor-associated Blood Vessels of Mice and Humans
BETHESDA, Md., June 11, 2007--A team of researchers at theNational Cancer Institute (NCI), part of the National Institutes ofHealth (NIH), has un
covered a set of genes that are turned on, orexpressed, at high levels only in the blood vessels that feedtumors in mice and humans. These genes, and the proteins theyencode, are important new potential targets for novel drugs thatcould selectiv...
Organon's Sugammadex Demonstrated a 9-12 Times Faster Recovery in
Phase III Pivotal Trial Compared to Neostigmine
OSS, the Netherlands, June 11, 2007-Sugammadex - the novelselective relaxant binding agent (SRBA) being developed by Organon,the human healthcare business unit of Akzo Nobel - demonstrated ina Phase III pivotal trial a 9-12 times faster reversal ofneuromuscular blockade as compared to neostigmine, without evidenceof post operative residual curarization (PORC) or re-occurrence ofmuscle relax...
ProtoKinetix's AAGP Dramatically Increases Recovery Rate of
Cryopreserved Stem Cells
VANCOUVER, British Columbia--(BUSINESS WIRE)--May 23, 2007 -ProtoKinetix Inc. (OTCBB:PKTX) has just received the results ofstudies conducted by ITTEC Stem, Inc. at the University of Finland.These outstanding results using AAGP(TM) in the cryopreservationprocess for stem cells demonstrate the vital importance of thismolecule in the rapidly expanding stem cell industry. This is thefirst serie...
Discovery's KL-4 Surfactant Technology Demonstrates Novel
Anti-Inflammatory Properties
Dis
covery's KL-4 Surfactant Technology Demonstrates NovelAnti-Inflammatory Properties New Surfaxin Data Presented At the 2007 Pediatric AcademicSocieties Annual Meeting WARRINGTON, Pa., May 9, 2007 (PRIME NEWSWIRE) -- Dis
coveryLaboratories, Inc. (Nasdaq:DSCO) announced that new data supportingthe anti-inflammatory properties of its novel KL-4 surfactant(lucinactant) replacement tec...
Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric
Academic Societies' Annual Meeting
Surfaxin Phase 2 BPD Clinical Data Selected and Presented asPlatform Presentation Aerosurf Utilizing Chrysalis Aerosol-Generator TechnologyDemonstrates Optimal Functional Activity WARRINGTON, Pa., May 8, 2007 (PRIME NEWSWIRE) -- Dis
coveryLaboratories, Inc. (Nasdaq:DSCO) announced that results from itspreviously completed Phase 2 clinical trial of Surfaxin(r)(lucinactant intr...
Eighty-one Percent of U.S. Adults say that Birth Control Pills and
Procedures Should Be Covered by Health Insurance
Support for Medical Use Approval and Insurance
Coverage VariesGreatly for Different Medical Treatments ROCHESTER, N.Y. - April 30, 2007-- Most U.S. adults supportapproving the use of medical treatments and procedures that canimpact people's quality of life, including birth controltreatments, in-vitro fertilization, drugs to treat erectiledysfunction and improve memory and to...
Millennium Discovers Biomarkers Potentially Predictive of Response
to Velcade (Bortezomib) for Injection
- Findings Published in Blood Highlight Millennium Leadership inPersonalized Medicine and Could Strengthen the Role of VELCADE asFoundation of Therapy in Broad Range of Multiple Myeloma Patients - CAMBRIDGE, Mass., April 17, 2007 /PRNewswire-FirstCall/ --Findings published in the April 15th issue of Blood show that ateam of researchers led by Millennium Pharmaceuticals, Inc. hasdis
covered...
Research Supported by Samuel Waxman Cancer Research Foundation
Discovers Mode of Action of Arsenic-Based Drugs in Destroying
Cancer Cells
NEW YORK--(BUSINESS WIRE)--Apr 16, 2007 - Arsenic, a naturallyoccurring element, has been used in therapeutic compounds for over2,000 years, and even now remains a venerable constituent of thetraditional Chinese pharmacopeia. Today, due in measure to the efforts of investigators supportedby grants from the Samuel Waxman Cancer Research Foundation's(SWCRF) "Institute Without Walls," an ars...
CytRx Announces Positive Results of Arimoclomol in Preclinical
Stroke Recovery Studies
LOS ANGELES--(BUSINESS WIRE)--Apr 4, 2007 - CytRx Corporation(NASDAQ:CYTR) today announced positive results of additional animalstroke studies indicating that CytRx's lead drug candidatearimoclomol significantly accelerated the re
covery of sensory andmotor function in an experimental rat model of stroke, even whentreatment was withheld as long as 48 hours after stroke wasinduced. These data...
Researchers Discover a Common Variation in a Gene Segment that
Increases the Risk for Prostate Cancer
BETHESDA, Md., April 1, 2007--Researchers report that avariation in a portion of DNA strongly predicts prostate cancerrisk and that this common variation may be responsible for up to 20percent of prostate cancer cases in white men in the United States.The research was conducted by investigators from the NationalCancer Institute (NCI), part of the National Institutes of Health,and their p...
Major Discovery Raises Prospect of Better Patient Care By Improving
Platelet Life Span
MELBOURNE, Australia, March 23, 2007 /PRNewswire/ -- Scientistsat WEHI have made a dis
covery with potentially profoundimplications for the care of patients, especially those undergoingcancer chemotherapy. The research team led by Drs Benjamin Kile and David Huang hasdis
covered that platelet life span is controlled by two keymolecules. The dis
covery raises the prospect of developing...
Alnylam and Stanford University Scientists Discover New Role for
microRNAs (miRNAs) in T Cell Biology and Immunity
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Mar 22, 2007 - AlnylamPharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeuticscompany, announced today publication of a study in the journal Cellby Alnylam and Stanford University scientists on the role of miRNAsin immunity. In the pre-clinical study, a specific miRNA, miR-181a,was shown to play an important role in controlling T cellresponsivenes...
Vaxiion Researchers Discover Novel Vaccine Delivery System in
Collaboration with San Diego State University
SAN DIEGO--(BUSINESS WIRE)--Mar 8, 2007 - Vaxiion Therapeutics,Inc. today announced that its researchers, in collaboration withSan Diego State University, have dis
covered a 'minicell' vaccinedelivery system that has potential to protect against severaldisease-causing infections. These findings were published in an advance online edition ofthe journal, Vaccine, and the paper was published...
IR BioSciences Announces Data Demonstrating Radilex Stimulation of
Stem Cells Results in Hematopoietic Recovery Following Lethal
Irradiation
Animal Data Shows Prolonged Survival AND Increased PlateletConcentrations SCOTTSDALE, Ariz., March 08, 2007 /PRNewswire-FirstCall/ --ImmuneRegen BioSciences, a wholly-owned subsidiary of IRBioSciences Holdings, Inc. announced today that ongoing analysis ofdata acquired from previously performed animal efficacy studies hasrevealed evidence that ImmuneRegen's developmental stage product,Ra...
Major Gene Study Uncovers Secrets of Leukemia
St. Jude Study Scans 350,000 Locations Across the Genome From 242Patients and Identifies New Mutations That Contribute to AcuteLymphoblastic Leukemia, Suggesting New Targets for Improved Therapy MEMPHIS, Tenn., March 07, 2007 /PRNewswire/ -- Investigators atSt. Jude Children's Research Hospital have dis
covered previouslyunsuspected mutations that contribute to the formation of pediatricac...