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Cord in Medical Technology

Congresswoman Supporting Spinal Cord Research Intended to Benefit U.S. Veterans

MIAMI, Oct. 22 /PRNewswire-USNewswire/ -- Congresswoman Debbie Wasserman Schultz will present a new initiative with St. Thomas University and the U.S. Department of Defense to support spinal cord injury research. St. Thomas University Biology Professor Jeffery Alan Plunkett - a leader in spina...

Neuralstem Licenses Cleveland Clinic Spinal Cord Injection Technology

ROCKVILLE, Md., Oct. 14 /PRNewswire-FirstCall/ -- Neuralstem Inc., (Amex: CUR ) today announced that it has licensed the rights to three inventions from Cleveland Clinic pertaining to Targeted Spinal Cord Therapeutics Delivery. All three inventions were developed by Dr. Nicholas Boulis MD, fo...

Synapse Biomedical Receives FDA Approval of NeuRx Diaphragm Pacing System (DPS)(TM) For Spinal Cord Injury Breathing Applications

NeuRx DPS(TM) Allows Patients To Breathe Without Ventilator Clinical Trials Also Underway For ALS Patients CLEVELAND, June 18 /PRNewswire/ -- Synapse Biomedical Inc. (http://www.synapsebiomedical.com ) announced today it has received approval from the U.S. Food and Drug Admi...

Auxilium Pharmaceuticals, Inc. Announces XIAFLEX(TM) Meets Primary Endpoint With Statistical Significance (p<0.001) in CORD I Pivotal Phase III Study for Dupuytren's Contracture

XIAFLEX also Meets Primary Endpoint (p III Study Pharmacokinetic Study Demonstrates Lack of Systemic Exposure of XIAFLEX Serious Adverse Events Occurring at a 0.33% Rate per XIAFLEX injection Conference call scheduled for today, June 3, at 8:45 a.m. Eastern T...

Alseres Pharmaceuticals Announces 12 Month Interim Results from the Phase I/IIa Cethrin(R) Clinical Trial in Acute Spinal Cord Injury

Results show promising neurological recovery in severely-injured, acute cervical spinal cord injury patients treated with Cethrin HOPKINTON, Mass., May 12 /PRNewswire-FirstCall/ -- Alseres Pharmaceuticals, Inc. (Nasdaq: ALSE ) today announced 12-month interim data from its Phase I/IIa c...

Alseres Pharmaceuticals, Inc. to Address a Congressional Briefing on Paralysis Research and the Spinal Cord Injury Community at 'Working 2 Walk' in Washington, DC, April 13-15, 2008

Dr. Mark Hurtt, Chief Medical Officer, to present interim results of the Cethrin(R) Phase I/IIa Clinical Trial in Acute Spinal Cord Injury HOPKINTON, Mass., April 9, 2008 /PRNewswire-FirstCall/ -- Alseres Pharmaceuticals, Inc. (Nasdaq: ALSE ) announced that on April 15, 2008, Dr. Mark Hurtt...

Early Research Suggests Umbilical Cord Blood Cell Therapy May Reduce Progression of Alzheimer's Disease

Study Highlights Growing Therapeutic Value of Cord Blood Stem Cells OLDSMAR, Fla., March 27 /PRNewswire-FirstCall/ -- Stems cells derived from umbilical cord blood are showing early potential in fighting Alzheimer's disease, according to results from a new preclinical study published in the ...

Alseres Pharmaceuticals Concludes Enrollment in the Cethrin(R) Phase I/IIa Clinical Trial in Acute Spinal Cord Injury

Company plans to begin Phase IIb study in the first half of 2008 HOPKINTON, Mass., Jan. 7 /PRNewswire-FirstCall/ -- Alseres Pharmaceuticals, Inc., (Nasdaq: ALSE ), announced today that it has concluded enrollment in the Phase I/IIa clinical trial of Cethrin in acute spinal cord injury (SC...

Alseres Pharmaceuticals' Announces Expansion of the Cethrin(R) Acute Spinal Cord Injury (SCI) Phase I/IIA Clinical Trial

Data Safety Monitoring Board (DSMB) Authorizes Enrollment of Cervical Patients at Current Highest Authorized Dosage Level HOPKINTON, Mass., Sept. 24 /PRNewswire-FirstCall/ -- Alseres Pharmaceuticals (Nasdaq: ALSE ) today announced that its independent Data Safety Monitoring Board (D...

Mayo Clinic Clarifies Diagnosis and Treatment for Rare, Serious Blood Vessel Disease of Brain and Spinal Cord

ROCHESTER, Minn., Oct. 18 /PRNewswire-USNewswire/ -- Mayo Clinic has clarified the methods of diagnosis and optimal management of a rare and little-understood blood vessel disease of the brain and spinal cord that often leads to stroke or death. Primary central nervous system vasculitis (PCNSV...

Research Indicates Geron's Human Embryonic Stem Cell-Based Therapeutic for Spinal Cord Injury Evades Direct Attack by the Human Immune System

MENLO PARK, Calif.--(BUSINESS WIRE)--Jun 11, 2007 - Geron Corporation (Nasdaq:GERN) today announced the presentation of research studies indicating that GRNOPC1, the company's human embryonic stem cell (hESC)-based therapeutic for the treatment of spinal cord injury, evades a direct attack by the h...

Clinical Trial Suggests Bone Marrow Stem Cells Are Useful for Spinal Cord Injury; PrimeCell Therapeutics Provided Pre-Clinical Study

SYDNEY, Australia--(BUSINESS WIRE)--Jun 27, 2007 - PrimeCell(TM) Therapeutics LLC (http://www.primecelltherapeutics.com) today announced that it provided research support and pre-clinical studies for a clinical trial to assess the safety, feasibility and efficacy of implanting autologous bone marro...

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

...ure, radiation to bone, surgery to bone, or spinal cord compression) compared with those receiving Zometa ...re, radiation to bone, surgery to bone, and spinal cord compression - to measure the effectiveness of deno...one, radiation to bone, surgery to bone, or spinal cord compression. All are serious complications for adv...

Cryo-Cell Announces C'elle(SM) Research and Development Collaboration with Cryopraxis Cryobiology Ltd.

...-degree relatives in a manner similar to umbilical cord blood stem cells. Based on the continued success o... Cryopraxis is a leader in stem cell, bone marrow, cord blood research and development. Cryopraxis is comm... largest in the World. It is the largest umbilical cord blood bank in Brazil. The umbilical...

Denosumab Demonstrates Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Breast Cancer Patients With Bone Metastases

...ure, radiation to bone, surgery to bone, or spinal cord compression) (hazard ratio 0.82, 95 percent CI: 0....re, radiation to bone, surgery to bone, and spinal cord compression - to measure the effectiveness of deno...one, radiation to bone, surgery to bone, or spinal cord compression. All are serious complications for ad...

Inspiration for 'My Sister's Keeper' Speaks Out

...ter develop to be Molly's little brother Adam. The cord blood from Adam's placenta would be used for a blo...n working with Dr. Schoolcraft. "We decided Adam's cord blood would be used to attempt to save Molly's lif... Today all the Nash children are thriving. Adam's cord blood succeeded in curing Molly's leukemia. While...

UPCI Joins ExCell Research Study Using Stem Cells for Leukemia and Lymphoma Patients

...enitor cells taken from a single unit of umbilical cord blood and then transplanted in combination with no...tic Stem Cell Transplant Program. "Using umbilical cord blood stem cells instead of a traditional bone mar...transplant can't find matching bone marrow donors. cord blood could be an alternative of choice. Pr...

ThermoGenesis Announces National Institute of Health Grant

...ed for the processing of stem cells from umbilical cord blood, while the Res-Q a point-of-care device sche...System , an automated cryogenic device, is used by cord blood stem cell banks in more than 25 countries for cryopreserving and archiving cord blood stem cell units for transplant. AX...

Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting

...als, USA. "In addition, NT-201 showed results in treating upper limb spasticity sufferers of various etiologies including stroke, brain injury, spinal cord injury, multiple sclerosis or cerebral palsy, warranting additional studies as a potential treatment option for a wide scope of patients." NT-201...

Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support

... Molecule Stem Cell Modulator Administered in Dual cord Blood Transplant for Hematologic Malignancy L...T1050 during the standard course of dual umbilical cord blood transplant in adult patients with hematologi...er in the worldwide registries. Because umbilical cord blood units are readily available from...

New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure

...ypersensitivity to other sulfonamide derived drugs Fetal/Neonatal Morbidity and Mortality Thiazides cross the placental barrier and appear in cord blood. There is a risk of fetal or neonatal jaundice, thrombocytopenia, and possibly other adverse reactions that have occurred in adults. Hepat...

BioMarin Initiates Phase 1/2 Clinical Trial for GALNS for Morquio A Syndrome

...tributes to sinopulmonary infections. Odontoid dysplasia and ligamentous laxity can commonly cause cervical spinal instability and potentially spinal cord compression. Other symptoms may include recurrent infections, hearing loss, corneal clouding, and heart valvular disease. Initial symptoms often becom...

Discovery's Edge Spring Issue - http://discoverysedge.mayo.edu

...verysedge.mayo.edu/de09-1-neuro-farrer-perry/ Breathing After Spinal cord Injury -- Strengthening Remaining Connections Breathing is second nature to most of us, but to victims of spinal cord injury (SCI) it may be anything but certain. Mayo researchers are exploring...

Astrocytes Help Separate Man From Mouse

...strocytes are full partners in the basic working of the brain; and astrocytes are central to conditions like stroke, Alzheimer's, epilepsy, and spinal cord injury. "Dogma is slow to change, and one of the dogmas of neuroscience is that astrocytes are support cells that don't do much themselves," said...

CSL Behring Receives Orphan-Drug Exclusivity for RiaSTAP(TM), First and Only Approved Treatment of Acute Bleeding Episodes in Patients with Congenital Fibrinogen Deficiency

...roximately 300 patients. Symptoms of congenital fibrinogen deficiency include excessive bleeding following injury, bruising, bleeding of the umbilical cord at birth and from the site of the umbilical stump in a newborn, spontaneous bleeding and bone, joint or tissue hemorrhage. Diminished concentrations o...

Quark Pharmaceuticals Presents at Asia TIDES Conference

...NA intellectual property arena, as well as the ability for non-invasive delivery of siRNA to other target tissues including the eye, ear, lung, spinal cord and brain. PF-4523655 (RTP801i-14), currently in Phase II clinical trials, is a synthetic, chemically modified siRNA designed to inhibit the expr...

Neuralstem's Human Stem Cells Integrate into Nervous System of Rats with Animal Model of ALS

...uman nervous system, such as in an ALS or a spinal cord injury patient." "This is an important milest...al stem cells (hNSCs) isolated from a fetal spinal cord region were grafted into the spinal cord of rats with a genetic mutation (SOD-1 G93A) that ...

Breast Cancer Patients May Have a New Treatment Option When Cancer Spreads

...the bone metastases and a lower dose to the spinal cord and other normal tissues than conventional externa..." she explains. "The negligible dose to the spinal cord would also make it possible to treat recurrent spi... collapse. And, due to the proximity of the spinal cord and nerves, those tumors can lead to serious neuro...

Neuralstem's ALS Trial on Clinical Hold

...NYSE Alternext US: CUR) announced today its spinal cord stem cell trial to treat ALS is on clinical hold a...ce neural stem cells of the human brain and spinal cord in commercial quantities, and the ability to contr...ude: Ischemic Spastic Paraplegia, Traumatic Spinal cord Injury, Huntington's disease and Amyotrophic Later...

Groundbreaking Paper Publishes Long Term Results of a Successful Phase I Clinical Trial Using Autologous Neural Stem Cells to Treat Parkinson's Disease

...on as it received final approval from the FDA. It is also planning Phase I studies for multiple systems atrophy, atypical parkinsonism, stroke, spinal cord and brain injuries, and Alzheimer's disease. The company was founded in 1998 and is headquartered in Los Angeles, California. FOR MORE INFORM...

Alseres Pharmaceuticals Completes Enrollment in First Stage of the Altropane(R) POET-2 Phase III Program

...ant-protein-based drug designed to promote nerve repair after acute spinal cord injury , demonstrated positive interim results in a Phase I/IIa clinical tr...arch and pre-clinical programs include, Inosine for the treatment of spinal cord injury and stroke, Oncomodulin for the treatment of ocular injury and disea...

Cymbalta(R) Significantly Reduced Osteoarthritis Knee Pain in New Study

...rvey Short Form-36 (SF-36) and EuroQoL Questionnaire - 5 Dimension. About Cymbalta Serotonin and norepinephrine in the brain and spinal cord are believed to both mediate core mood symptoms and help regulate the perception of pain. Based on preclinical studies, Cymbalta is a balanced and pot...

ThermoGenesis Announces MXP Involvement in New Regenerative Medicine Initiatives

...ss technology platform, which is routinely used in cord blood banking processing by both private and public cord blood banks throughout the world. The MXP features...System , an automated cryogenic device, is used by cord blood stem cell banks in more than 25 countries fo...

Study Shows No Standardized Approach to Epidural Steroid Injections for Back Pain

...s in the lumbar (low back) region are low risk, injections in the thoracic (mid back) and cervical (neck) region have the risk of injury to the spinal cord and brain. It usually consists of a steroid diluted with sterile saline, and sometimes also addition of local anesthesia. Controversy exists on the ...

Advances in Science and Treatment of Pain Presented at 25th Annual American Academy of Pain Medicine Meeting January 28 - 31, 2009

...ause injuries and diseases which damage the spinal cord and brain so that in many cases chronic pain becom...rom 5-6:30 PM and Jan. 29 from 9-10 AM Spinal cord Stimulation for Chronic Pain, Poster 117 Spinal cord Stimulation for Chronic Pain Review, Poster 121 ...

Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function

...NA intellectual property arena, as well as the ability for non-invasive delivery of siRNA to other target tissues including the eye, ear, lung, spinal cord and brain. PF-4523655 (RTP801i-14), currently in Phase II clinical trials, is a synthetic, chemically modified siRNA designed to inhibit the expr...

Molecular Marker Identifies Normal Stem Cells as Intestinal Tumor Source

.... Gilbertson holds the Sydney Schlobohm Leadership Chair of Research from the Brain Tumor Society and the Howard C. Schott Research Chair from Malia's cord Foundation. St. Jude Children's Research Hospital St. Jude Children's Research Hospital is internationally recognized for its pion...

Sosei Confirms the Safety of SD118 in Two Phase I Trials

...ystem and persists for months or years even after the initial damage had been healed. It can occur in a variety of traumatic diseases including spinal cord injury and nerve compression. Also, it is a common secondary symptom in diseases like diabetes, cancer and herpes zoster infection, and can occur afte...

Research Explores the Effects of Stem Cell Source and Patient Age on Stem Cell Transplantation Outcomes

...nique for increasing the presence of stem cells in cord blood for transplantation will also be shared duri... the stem cells (bone marrow, peripheral blood, or cord blood) and by their origin - autologous (from the ...of Unrelated Bone Marrow, Peripheral Blood, and cord Blood [Abstract #151] M ary Eapen, ...

Enobia Initiates Infantile Enzyme Replacement Trial for Rare Bone Disease

...ders (CORD). "CORD is delighted to have played a role in helping to bring this infant to Canada to receive potentially life-saving therapy," cord President Dr. Durhane Wong-Rieger said. "It is not often that Canada gets to be a leader in rare disorders research and this clinical trial is an affi...
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