CHO in Medical Technology

Artelis and Selexis Report Record Antibody Production Levels in CHO Cells of Over 31 Grams Per Liter

BRUSSELS, Belgium and GENEVA, Sept. 3 /PRNewswire/ -- Artelis SA and Selexis SA announced today a new milestone in CHO based monoclonal antibody production with the achievement of manufacturing yields of over 31 grams per liter. This record level was accomplished by applying two highly innovat...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

... in a broad Phase 3 program in patients who cannot adequately control their cholesterol levels with current therapies and who need new treatment options. ... also met each of its three secondary endpoints of reduction in apoB, total cholesterol and non-HDL-C. Genzyme continues to refine its European st...

Juvenile Diabetes Research Foundation, The Genomics Institute of the Novartis Research Foundation Announce Innovative Diabetes Drug Discovery and Development Partnership

... creation of a multi-product pipeline for beta cell regeneration, a therapeutic priority for JDRF." Projects within the collaboration will be chosen and managed by a combined review committee of JDRF and GNF representatives, with oversight from a Scientific Advisory Board and JDRF volunteers. ...

Cancer Centers of North Carolina Offers HDR Brachytherapy for Treatment of Cancerous Tumors

...ance in brachytherapy allows physicians to deliver precise radiation treatment to a patient's cancerous tumor and is rapidly becoming the treatment of choice for certain types of cancer. With HDR brachytherapy, radiation is delivered directly to the cancer target through the use of catheters, nee...

DNA Helps Reunite Children With Their Families

...it would be impossible to bring them home. Perhaps an international DNA database would help reunite these children with their families. Lorente chose to collaborate with the UNT Health Science Center because of its reputation as a world-renowned center for human identification. The Center has bee...

ARUP Laboratories Applauds FDA's Decision on the Value of KRAS-Mutation Testing in Colorectal Cancer

...s to highly esoteric molecular and genetic assays, for patients nationwide. Rather than competing with its clients for physician office business, ARUP chooses instead to support clients' existing test menus by offering highly complex and unique tests, with accompanying consultative support, to enhance t...

TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

...t it had a beneficial effect on lipids (molecules in the blood that include cholesterol and triglycerides). "It's extremely unusual to analyze the...he combined effects of GH and sex-steroids on glucose tolerance, elevated cholesterol and insulin sensitivity--changes in older adults that occur as a r...

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

...Dr. Atul Mehta, Clinical Director of the Lysosomal Storage Disorders Unit, Royal Free Hospital, London. "Velaglucerase alfa appears to be an excellent choice for Type 1 Gaucher patients. The prospect of having another treatment option available to help patients achieve therapeutic goals is very importan...

Study Shows Cancer Vaccines Led to Long-Term Survival for Patients with Metastatic Melanoma and to Long Periods of Disease Control After Completion of Therapy

...poration has endorsed Hoag as Orange County's most preferred hospital for the past 13 consecutive years. For an unprecedented 13 years, residents have chosen Hoag as the county's best hospital in a local newspaper survey. In order to meet the growing needs of Irvine and South County residents, Hoag will...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

...owerful solution to the challenge of making gene knockouts in cells and in whole organisms. We believe that this technology will become the method of choice for genome engineering in cells, plants and transgenic animals." In the first commercial application of this technique, OMT, a private bi...

July 2009 Mayo Clinic Women's HealthSource Highlights Food Storage Safety, Energy Therapies and Vitamins and Minerals

...t food to energy and helps improve circulation and cholesterol levels. Researchers have found that, in h...n can reduce low-density lipoprotein (LDL or "bad" cholesterol) and triglycerides and raise high-density lipoprotein (HDL or "good") cho lesterol. However, the doses needed for these effe...

Accent on Aesthetics Plastic Surgery Medical Center Selects Artefill to Meet Growing Patient Demand for a Longer Lasting Dermal Filler

...erience, Dr. Rosenberg offers a comprehensive menu of the most advanced surgical and noninvasive procedures available. You can feel confident you have chosen a doctor who can give you the beautiful, natural-looking results you want. You'll also appreciate his warmth and sensitivity - with Dr. Rosenberg ...

Teeth and Gums Also Benefit from the Healing Power of Aloe Vera

... to see what products have received the organization's seal of quality. "Thankfully, consumers with sensitive teeth or gums have a number of choices when it comes to their oral health, and aloe vera is one of them," says AGD spokesperson Eric Shapria, MS, DDS, MAGD, MA. "If they are interested...

New Results From ARTEN Study of Nevirapine Plus Tenofovir and Emtricitabine (TDF/FTC) Versus Boosted Protease Inhibitor Regimen of Atazanavir/Ritonavir Plus TDF/FTC Revealed

...e patients and 3.9 mg/dL among ATV/r patients (p<0.0001). The mean total cholesterol/HDL ratio in patients receiving nevirapine decreased from baseline...creased 28.1 mg/dL in the ATV/r group (p <0.0001). Mean increases in LDL cholesterol were 15 mg/dL in the nevirapine group and 10.5 mg/dL in the ATV/r ...

Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome

...e metabolite have demonstrated reductions in blood pressure, triglycerides, cholesterol levels, C-reactive protein, and fasting blood glucose levels. Enzy...ed, pointing to an outstanding safety profile. Increases in HDL, the "good" cholesterol and increased insulin sensitivity have also been documented along ...

BioCryst Pharmaceuticals Reports Positive Results of Shionogi & Co. Sponsored Phase 3 Studies of i.v. Peramivir for Influenza

...fect the forward-looking statements contained herein include: that peramivir may not receive emergency use authorization; that the U.S. government may choose not to ship peramivir to the CDC Strategic National Stockpile; that to the extent peramivir is used as a treatment for H1N1 flu (or other strains ...

New Research Shows: Neurofeedback is an 'Evidence-Based' Treatment for ADHD

... EEG and Clinical Neuroscience demonstrating clinical efficacy in the treatment of epilepsy. Interested clients are advised to make an informed choice regarding Neurofeedback therapists, since there is a large heterogeneity in neurofeedback treatment approaches and clinicians. It is advised to lo...

Music & Medicine: Unique Collaboration Combines Performing Arts and Science

...e how far the hands must move to reach some of the chords common in piano pieces. Sensors under the pian... pain. "I have very small hands. When I span a chord or octave, I have to stretch my hands a lot, so...," Yoshimura said. "There are many pieces with big chords, so the repertoire I can play is limited." ...

Risks of Delaying ACL Reconstruction in Young Athletes May Be Too High, Study Shows

...measured the independent risk factors for and relative risk of meniscal and chondral injuries in pediatric ACL patients," said author, Theodore J. Ganley,...parable medial meniscus tears, an 11-fold increase in lateral compartment chondral injuries and a three-fold increase in patellotrochlear injuries. Issu...

Ipsogen Reports Incorporation of the Genomic Grade in the 2009 St. Gallen International Consensus Meeting on the Primary Treatment of Early Breast Cancer

...ing breast cancer. As for leukemia, Ipsogen's goal is to provide diagnostic information that was not available until now. Ipsogen is also a partner of choice for biopharmaceutical companies committed to the development of 'companion diagnostic' tests. Strengthened by its first-rate scientific, cl...

First Patient of NOTES Investigational Device Exemption (IDE) Study Successfully Treated With Ethicon Endo-Surgery Devices

... an investigational device exemption (IDE) to study devices for NOTES, will include up to 40 subjects undergoing either a diagnostic peritoneoscopy or cholecystectomy (gallbladder removal). Surgeons will use one of four different NOTES procedures supplemented with laparoscopic assistance. In addition t...

Relievant Medsystems Announces Completion of $20 Million Financing

...seek treatment for back pain. Unfortunately, nearly two million of these patients fail to respond to conservative treatment. These patients have few choices - escalating use of pain medications, continued suffering or invasive surgery. Based on the research of Michael Heggeness, MD, PhD of the B...

New AHRQ Study Finds Mixed Evidence on Use of Radiofrequency Catheter Ablation for Treating Atrial Fibrillation

...mpare alternative treatments for health conditions and make the findings public. The program is intended to help patients, doctors, nurses, and others choose the most effective treatments. Information, including the new report, can be found at http://www.effectivehealthcare.ahrq.gov . Editor's ...

Shire has Filed a Treatment Protocol for Velaglucerase Alfa for Gaucher Disease

...hire.com ) on its progress with its discussions with the FDA and other regulatory bodies about the development of velaglucerase alfa as an alternative choice for Gaucher Disease patients. Background on Gaucher Disease Gaucher Disease is an autosomal recessive disease and the most prevalent...

PARI LC Plus and PRONEB Ultra Used in Two Perforomist Studies on Improving COPD Therapies

... used to show that nebulized formoterol fumarate (Perforomist, DEY LP, Mylan Inc.) improves pulmonary function. "We are pleased that researchers chose PARI products as the exclusive nebulizer systems for recent studies comparing maintenance treatments for COPD. Sutherland et al. used an open-labe...

New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF

...t. HP-hMG, contains both FSH and hCG-driven (human chorionic gonadotropin) LH-activity (luteinizing horm...or implication on the decision-making process when choosing the appropriate gonadotropin for ovarian sti...ollicle stimulating hormone) and hCG-driven (human chorionic gonadotropin) LH-activity (luteinizing horm...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

...anage and the availability of eslicarbazepine acetate adds an important new choice of therapy for patients who are in vital need of better seizure control...nd is based in S. Mamede do Coronado, Portugal. It is the partner of choice for many companies, having a strong presence in the Iberian peninsula a...

SUNY Youth Sports Institute Convenes Top Experts in NYC Next Week to Present Research & Analysis on Energy Drink Health Impacts

...supplements and aggressively marketed, they have a special allure with young people. This causes confusion with adults who are trying to provide smart choices to their children and to the children they coach or teach. Little is known about the contents of each container, yet their brand names and market...

New Study Shows that Prebiotics, as Used by Jackson GI Medical, Increases Lifespan by 33%

...a Cambridge University Journal), clearly shows that Prebiotics reduce cholesterol and triglycerides, control body weight, and increase lifespan by 3...biotics. Additionally, the "prebiotic" rats showed material reductions in cholesterol and body weight versus the control group. Significantly, th...

ALP Life Sciences, LLC Announces Nanoveson(TM) Patent Filing and Whitepaper Availability on Proposed Therapy for Non-Alcoholic Fatty Liver Disease (NAFLD) and Comorbid Diseases

...lipids and lipid membrane fusion and aggregation in the intestines. Molecular compounds including biliary phospholipids, arachidonic acid metabolites, cholesterol, methyl metabolites, phthalate esters, and other compounds sequestered in vesicle membranes are expected to be a rich source of disease state...

Infant Formula Company Teams With the University of Virginia Pediatrics Department to Conduct Clinical Studies

... know breastfeeding is best for babies," said V.P. Cynthia M. Barber, Ph.D., who directs regulatory, medical, and clinical affairs at PBM. "If parents choose to supplement breast milk with formula, our store-brand formulas are nutritionally equivalent to Enfamil(R) LIPIL(R) and Similac(R) Advance(R) for...

Cytel Signs Cooperative Research And Development Agreement With FDA Center for Devices and Radiological Health (CDRH)

...n, and Chief Technology Officer, will lead the development effort as Cytel Principal Investigator. Dr. Patel commented, "We are honored that CDRH chose Cytel as their partner for developing validated, documented, and commercially available Bayesian software. The CRADA is completely aligned with our...

Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th

...9 of 27 patients); ORR=89% (24 of 27 patients) in relapsed/refractory indolent NHL, nearly all of whom had received aggressive first-line therapy with choP-R. The Pan Pacific Lymphoma Conference poster is available at http://www.celltherapeutics.com/investor_updates . About the PIX 301 EX...

China Animal Welfare Law Under Review While 36,000 Dogs Culled

...re's (IFAW - www.ifaw.org ) Asia Regional Director, Grace Ge Gabriel, "Mass killing of dogs is ineffective in controlling rabies in the long-term. By choosing not to implement a sensible rabies vaccination program, Hanzhong government has failed to protect the health of its citizens. Furthermore, the b...

Glybera(TM) Shows Long-Term Health Benefits

... the obstacles that have hindered development of gene therapy technologies into drugs. Using adeno-associated viral vectors as the delivery vehicle of choice for therapeutic genes, the company has designed and validated a stable, scalable, commercially attractive and GMP-compliant AAV manufacturing plat...

Study Demonstrates Efficacy of Pitavastatin in Elderly Patients

...ws the effectiveness of pitavastatin to lower LDL [low-density lipoprotein] cholesterol in a group of elderly patients with primary hypercholesterolemia o...sident of scientific affairs, Kowa Research Europe. "It may be difficult to choose a suitable statin for elderly patients with primary hypercholesterolemi...

UPCI Joins ExCell Research Study Using Stem Cells for Leukemia and Lymphoma Patients

.... However, more than half the number of patients in need of a transplant can't find matching bone marrow donors. Cord blood could be an alternative of choice. Previous research has shown that umbilical cord blood stem cells offer a viable therapeutic option for leukemia and lymphoma patients with...

VIA Pharmaceuticals Meets With FDA to Discuss Next Steps For VIA-2291 and Phase 3 Outcome Trial in Cardiovascular Disease

...and stroke. In addition, VIA's pipeline of drug candidates includes other compounds to address other underlying causes of cardiovascular disease: high cholesterol, diabetes and inflammation. For more information, visit: http://www.viapharmaceuticals.com . Forward Looking Statements This ...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

... The incidence and magnitude of changes in weight, prolactin, triglyceride, cholesterol and hepatic enzyme levels were greater in adolescents than adults....high, elevations in triglyceride levels and modest mean elevations in total cholesterol have been observed with Zyprexa use. Potential consequences ...

Oramed Pharmaceuticals to Present at the 8th National Life Science & Technology Week ILSI -BIOMED Conference, Israel 2009

...FirstCall/ -- Oramed Pharmaceuticals, Inc. (OTCBB: ORMP.OB) ( http://www.oramed.com ), a developer of oral delivery systems, announced that Oramed was chosen to present at the 8th National Life Science & Technology Week ILSI-BIOMED Conference, Israel 2009. The presentation will be given by Mr. Nadav...