Animal in Medical Technology

China Animal Welfare Law Under Review While 36,000 Dogs Culled

BEIJING, June 16 /PRNewswire-USNewswire/ -- Today the Chinese state media announced that the dog cull in Hanzhong city, Shaanxi Province has reached a death toll of 36,000. Claiming rabies outbreak, the city has sent out dog-beating squads to kill any animal spotted on the street, stray or owned. ...

EUCODIS Bioscience Achieves Development Milestone in Second Collaboration With Lohmann Animal Health

VIENNA, Austria, and CUXHAVEN, Germany, June 18 /PRNewswire/ -- EUCODIS Bioscience, a company developing, manufacturing, and marketing enzymes and other proteins for the chemical industry, announced today that it has achieved an important milestone in the development of an undisclosed protein ...

Neuralstem's Human Stem Cells Integrate into Nervous System of Rats with Animal Model of ALS

Make Synaptic Contact with Host Motor Neurons ROCKVILLE, Md., March 9 /PRNewswire-FirstCall/ -- Transplanted human neural stem cells (hNSCs) developed by Neuralstem, Inc. (NYSE Alternext US: CUR) made synaptic contacts with the motor neurons of rats with ALS-like symptoms, a paper published i...

Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs

New study questions ability of human-animal hybrids to generate stem cells WORCESTER, Mass., Feb. 2 /PRNewswire-FirstCall/ -- Advanced Cell Technology, Inc. (OTC Pink Sheets: ACTC) and its collaborators reported today that human oocytes (or 'eggs') have the capacity to extensively reprogram...

Grapes May Aid a Bunch of Heart Risk Factors, U-M Animal Study Finds

Research shows that grape intake lowered blood pressure and signs of heart muscle damage, and improved heart function in lab rats ANN ARBOR, Mich., Oct. 29 /PRNewswire-USNewswire/ -- Could eating grapes help fight high blood pressure related to a salty diet? And could grapes calm other facto...

InNexus Lead Candidate DXL625 Outperforms Rituxan in Additional Animal Studies

- Biotech Begins to Demonstrate Strategy to Expand NHL Marketplace with Novel Antibody and Speedy DXL Screening Preclinical Development Program - BRITISH COLUMBIA, Canada, Sept. 16 /PRNewswire-FirstCall/ -- InNexus Biotechnology Inc. (TSX VENTURE: IXS; OTC Bulletin Board: IXSBF; http://www.i...

Variant of Mad Cow Disease May Be Transmitted by Blood Transfusions, According to Animal Study

WASHINGTON, Aug. 28 /PRNewswire-USNewswire/ -- Blood transfusions are a valuable treatment mechanism in modern medicine, but can come with the risk of donor disease transmission. Researchers are continually studying the biology of blood products to understand how certain diseases are transmitt...

Catalyst Pharmaceutical Partners Announces Publication of Animal Data Demonstrating Vigabatrin Effective for Weight Loss

CORAL GABLES, Fla., Aug 21 /PRNewswire-FirstCall/ -- Catalyst Pharmaceutical Partners, Inc. (Nasdaq: CPRX ) today reported that animal data from a new study sponsored by scientists at the U.S. Department of Energy's Brookhaven National Laboratory appears to demonstrate that taking vigabatrin ...

Treatment Corrects Severe Insulin Imbalance in Animal Studies

--Could Become First Effective Drug for Rare Genetic Disorder in Children-- PHILADELPHIA, July 31 /PRNewswire-USNewswire/ -- Researchers have used a drug to achieve normal levels of blood sugar in animals genetically engineered to have abnormally high insulin levels. If this approach succe...

Blueberry-Supplemented Diet Shows Promise in Lowering Cholesterol in Animal Trials

PORTLAND, Maine, June 19 /PRNewswire/ -- New research published in the British Journal of Nutrition (Br J Nutr., Dec. 17, PMID: 18081945, 2007) shows that blueberries may have a cardio-protective effect, by significantly lowering cholesterol. Lead scientist, Wilhelmina Kalt, Ph.D, from Agricul...

Pew Commission Says Industrial Scale Farm Animal Production Poses 'Unacceptable' Risks to Public Health, Environment

WASHINGTON, April 29 /PRNewswire-USNewswire/ -- The current industrial farm animal production (IFAP) system often poses unacceptable risks to public health, the environment and the welfare of the animals themselves, according to an extensive 2 1/2-year examination conducted by the Pew Commissi...

Lixte Biotechnology Holdings Announces That Anti-Cancer Activity Against Glioblastoma in an Animal Model Was Reported at the Annual Meeting of the American Association of Cancer Research

EAST SETAUKET, N.Y., April 23 /PRNewswire-FirstCall/ -- Lixte Biotechnology Holdings (OTC Bulletin Board: LIXT) announced today that Dr. Jie Lu and Dr. Zhengping Zhuang of the Surgical Neurology Branch (SNB), National Institute of Neurological Disorders and Stroke (NINDS), National Institutes ...

Emisphere Technologies Announces Positive Results From Animal Studies on Oral B12 Using eligen(R) Technology

CEDAR KNOLLS, N.J., Feb. 7 /PRNewswire-FirstCall/ -- Emisphere Technologies, Inc. (Nasdaq: EMIS ) announced today that recent animal studies have demonstrated proof of concept that absorption of oral vitamin B12 using the company's proprietary eligen(R) technology was 15-30 times greater than...

Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study

CARMIEL, Israel, Jan. 22 /PRNewswire-FirstCall/ -- Protalix BioTherapeutics, Inc. (Amex: PLX ), today announced that it has achieved proof of concept results in an animal study conducted as part of its Acetylcholinesterase (AChE) Program. The Acetylcholinesterase (AChE) Program is being condu...

Researchers Use Magnetism to Target Cells to Animal Arteries

- Magnetically Guided Nanoparticles May Deliver Treatments to Human Organs - PHILADELPHIA, Jan. 7 /PRNewswire-USNewswire/ -- Scientists have used magnetic fields and tiny iron-bearing particles to drive healthy cells to targeted sites in blood vessels. The research, done in animals, may le...

Anadys Pharmaceuticals Announces Positive Results for ANA598 in Animal Model of Chronic Hepatitis C Virus Infection

ANA598 demonstrates significant antiviral activity in vivo SAN DIEGO, Jan. 3 /PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS ) announced preliminary data today from two studies of ANA598, a non-nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, in...

CSL Behring Study in Animal Models Shows Feasibility of Developing a Half-Life Extended Recombinant FVIIa that Retains Biologic Activity

In data presented at the ASH 49th annual meeting recombinant factor VIIa-albumin fusion protein seen as first step toward more convenient treatment option for hemophilia patients with inhibitors ATLANTA, Dec. 10 /PRNewswire/ -- CSL Behring today announced the results of a pre-clini...

Man's Best Friend May Open Door to Understanding Fibrotic Lung Disease in Human and Animal Populations

Human and Canine Respiratory Specialists Meet for First Time to Discuss Joint Research Efforts Into Pulmonary Fibrosis and Other Fibrotic Lung Diseases LAFAYETTE, Ind., Oct. 16 /PRNewswire-USNewswire/ -- In what is a growing trend among research scientists in the United States and the United...

One Shot of Gene Therapy Spreads Through Brain in Animal Study

- Method Has Potential for Correcting Devastating Genetic Diseases - PHILADELPHIA, Oct. 8 /PRNewswire-USNewswire/ -- By targeting a site in a mouse brain well connected to other areas, researchers successfully delivered a beneficial gene to the entire brain -- after one injection of gene the...

Inotek Pharmaceuticals Announces Publication of Animal Data from Study of PARP Inhibition as Potential Preventative of Brain Injury Following Stroke

BEVERLY, Mass.--(BUSINESS WIRE)--Apr 10, 2007 - Inotek Pharmaceuticals Corporation announced today the publication in the journal Stroke of preclinical animal data showing that the administration of a poly(ADP-Ribose) polymerase (PARP) inhibitor has a large protective effect on the survival of cert...

Medarex Presents Preclinical Data Demonstrating Potent Anti-Tumor Activity of Anti-CD19 and Anti-CD70 Antibody-Drug Conjugates in Cancer Animal Models

- Data presentations at American Association for Cancer Research annual meeting - PRINCETON, N.J., April 17, 2007 /PRNewswire-FirstCall/ -- Medarex, Inc. today presented preclinical data demonstrating potent anti- tumor activity from two separate studies exploring the efficacy and safety in animal...

RTA 402 Shown to Inhibit STAT3 in Animal Model and Holds Significant Promise for Treating Breast Cancer

IRVING, Texas--(BUSINESS WIRE)--May 15, 2007 - Reata Pharmaceuticals, Inc. today announced the publication of an article in the May 2007 issue of the journal Cancer Research showing that RTA 402, the company's Phase 2 development candidate for cancer, was highly effective in a rigorous animal model...

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

...didates in humans. The complexity of the human body cannot be perfectly, or sometimes, even adequately modeled by computer or cell culture systems or animal models. The length of time that it takes for us to complete clinical trials and obtain regulatory approval for product marketing has in the past vari...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...ta on ISIS-SGLT2Rx showing robust and sustained reduction in SGLT2 levels that resulted in a significant reduction in blood glucose levels in multiple animal species. Isis and its collaborators presented data on a number of other promising new diabetes and anti-obesity targets demonstrating that reduc...

Scientists Discover Origin of Malaria

...ratory of Stephen Rich, Ph.D., at the University of Massachusetts, Amherst. "It is now clear that a new disease that successfully jumps from an animal to a human can last not just for decades, but millennia or more," Wolfe said. "This makes the task of stopping future disease spillovers from animals ...

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

...didates in humans. The complexity of the human body cannot be perfectly, or sometimes, even adequately modeled by computer or cell culture systems or animal models. The length of time that it takes for us to complete clinical trials and obtain regulatory approval for product marketing has in the past vari...

FDA Advisory Committee Votes in Favor of SAPHRIS(R) (asenapine) for Acute Bipolar I Disorder and Acute Schizophrenia

...creates therapies that help save and improve lives around the world. The company applies its research-and-development platform to human prescription, animal health and consumer health care products. Schering-Plough's vision is to "Earn Trust, Every Day" with the doctors, patients, customers and other stak...

Pennsylvania Agriculture Department Issues Quarantine for Allegheny County Horse Stable

...rses consistent with the neurologic form of EHV-1 and alerted the Bureau of animal Health and Diagnostic Services on July 19. Symptoms of the neurolog...rs with further concerns may call the Department of Agriculture's Bureau of animal Health and Diagnostic Services at 717-772-2852. For more informat...

Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms

...mprove the quality of life for people worldwide. The Company's major divisions include Wyeth Pharmaceuticals, Wyeth Consumer Healthcare and Fort Dodge animal Health. The statements in this press release that are not historical facts are forward-looking statements that are subject to risks and u...

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... for the development of novel genetically modified animal models of human disease. ZFN technology will make...ryonic stem cells and allows rapid creation of new animal models." In the study published in Scien...ansgenic rats. The rat is a widely used laboratory animal with a well characterized immune system, a nearly ...

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

... creates therapies that help save and improve lives around the world. The company applies its research-and-development platform to human prescription, animal health and consumer health care products. Schering-Plough's vision is to "Earn Trust, Every Day" with the doctors, patients, customers and other stake...

Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA

...ese patients. The EMEA is a regulatory agency in the European Union (EU) primarily responsible for the protection and promotion of public and animal health, through the evaluation and supervision of medicines for human and veterinary use. The goal of EMEA's orphan drug program is to promote the de...

Cytokine PharmaSciences Initiates Phase I Study of Oral Anti-Inflammatory Agent, CPSI-2364

...pha, IL-1, IL-6, and IL-8. Semapimod has demonstrated activity in multiple animal models of inflammation and autoimmune disease, proof-of-concept studies tha...SI-2364, a more soluble salt of semapimod that makes oral dosing possible. animal models have confirmed the oral activity of CPSI-2364. About Cytok...

Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome

... natural dietary carotenoid astaxanthin that addresses metabolic syndrome, including liver and cardiovascular disease as well as diabetes. Preclinical animal studies with the Company's compounds or its active metabolite have demonstrated reductions in blood pressure, triglycerides, cholesterol levels, C-rea...

International Journal of Occupational and Environmental Health Features Discovery of Asbestos-Related Pain Origin from Scientists at the Karmanos Cancer Institute in Detroit

...iagnosed with asbestosis and pleural plaques, as established by the American Thoracic Society. These findings also support earlier human and animal reports that dusts produced by taconite mining can evoke the same biological responses as do other fibers already defined as asbestos or asbestiform m...

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

...ynthetic compounds, but regulate different genes. Specifically, we have discovered that these compounds do not promote breast or endometrial cancer in animal models, unlike many estrogen therapies. This suggests that these plant-derived ERb-selective compounds could lead to safer, more attractive alternativ...

Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV

...d improve lives around the world. The company applies its research-and-development platform to human prescription and consumer products as well as to animal health products. Schering-Plough's vision is to "Earn Trust, Every Day" with the doctors, patients, customers and other stakeholders served by its co...

Results From Drug Trials and New Risk Factors Announced at International Alzheimer's Conference

... In a surprising result from ICAD 2009, researchers found that treatment with Dimebon caused an increase in a brain protein, known as beta amyloid, in animal models of Alzheimer's. Beta amyloid is a protein that is the main constituent of plaques found in the brains of people with Alzheimer's. It is thought...

Results From Trials of DHA in Alzheimer's Disease and Age-Related Cognitive Decline

... makes fatty fish a good source of DHA. Dietary DHA is also available in foods enriched with algal DHA or fish oils, and dietary supplements. Previous animal studies and epidemiology in humans suggested that DHA may be beneficial in people with Alzheimer's. Alzheimer's Disease Cooperative Study ...

Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM)

...nd marketing of proprietary products for human and animal health markets worldwide. The fully-integrated com...l and has three operating divisions: Human Health, animal Health, and Food Safety. The Company's primary goa...ed by revenues from marketed products in human and animal health. Bioniche has been named one of the Top 50 ...