Samaritan's Alzheimer's Drug Caprospinol Suggests Brain May be Able
to Heal From Alzheimer's Disease
Animal Study Confirms Caprospinol's (SP-233) Ability to Clear BrainPlaque and Empower Rat Brain Cells to Recover Memory Function In Vivo 'Proof of Concept' Study Proposes Direct CorrelationBetween Removing Beta Amyloid Plaque and Memory Recovery LAS VEGAS, July 10, 2007 (PRIME NEWSWIRE) -- SamaritanPharmaceuticals Inc. (AMEX:LIV), a developer of innovative drugs,is ple...
Resveratrol Studies Suggest Broad Implications for SIRT1 Activation
in Neurodegenerative Diseases of Aging Such as Alzheimer's Disease
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jun 26, 2007 - SirtrisPharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical companyfocused on discovering and developing small molecule drugs to treatdiseases of aging, announced today that activation of SIRT1, amember of the sirtuin family of enzymes, was shown to protectagainst neurodegenerative diseases such as
Alzheimer's Disease andAmyotrophic Lat...
Accera, Inc. Announces Open-Label Data from Phase II Study in
Alzheimer's Disease at International Conference on Prevention of
Dementia
BROOMFIELD, Colo., June 11, 2007 /PRNewswire/ -- Accera, Inc.today is presenting data from an open-label extension of its PhaseIIb clinical trial of AC-1202 (Ketasyn) in
Alzheimer's disease (AD)at the
Alzheimer's Association's International Conference onPrevention of Dementia in Washington, D.C. Consistent with thefindings of earlier clinical and preclinical studies, AC-1202 wasshown to...
At the 2007 Alzheimer's Association International Conference on the
Prevention of Dementia - Neurochem's U.S. Principal Investigator
Presents Update on Tramiprosate (Alzhemed)
WASHINGTON, DC, June 11, 2007 /PRNewswire-FirstCall/ - Paul S.Aisen, M.D., Professor of Neurology and Medicine at GeorgetownUniversity Medical Center, and principal investigator in the UnitedStates of Neurochem Inc.'s North American Phase III clinical trialfor tramiprosate (ALZHEMED(TM)) will present today an update onNeurochem's investigational product candidate for the treatment ofAlzh...
Myriad Genetics Presents Mathematical Comparison of Disease
Modification Trial Designs at Alzheimer's ConferenceCurrent
Flurizan Phase 3 Study Design May Demonstrate Disease Modification
SALT LAKE CITY, UT, June 11, 2007 (MARKET WIRE via COMTEX NewsNetwork) -- Myriad Genetics, Inc. (NASDAQ: MYGN) (<a target="_blank" href="http://www.myriad.com/">www.myriad.com )announced today that it presented a mathematical comparison of a"Staggered Start" and a "Randomized Withdrawal" clinical trialdesign with a "Natural History Staggered Start" clinical trialdesign at the Alzheime...
Treating Heart Disease Risk Factors May Slow Alzheimer's Disease
Progression
- Late Life Weight Loss and "Motivational Reserve" May Also Affect
Alzheimer's Risk - WASHINGTON, June 10, 2007 /PRNewswire-USNewswire/ -- A new studysuggests that treating risk factors for heart disease and stroke,such as high blood pressure and diabetes, may slow the progressionof
Alzheimer's disease, according to research reported today at the2nd
Alzheimer's Association International Co...
Medivation's Dimebon Maintains Statistically Significant Benefit on
All Five Efficacy Endpoints in Alzheimer's Disease Trial After One
Year of Therapy
- Aggregate Benefit over Placebo Larger at One Year than at SixMonths - SAN FRANCISCO and WASHINGTON, June 11, 2007/PRNewswire-FirstCall/ -- Medivation, Inc. today announced that thebenefits of Dimebon over placebo in its double-blind,placebo-controlled Phase 2 study in mild-to- moderate
Alzheimer'sdisease were statistically significant on all five study endpointsat 12 months. Importantl...
Clinical Update - Debio 9902 (ZT-1) for Alzheimer's Disease
Presentation of Final Phase I Monthly Implant and Phase IIa DailyOral Results LAUSANNE, Switzerland, June 11, 2007 /PRNewswire/ -- DebiopharmGroup (Debiopharm), a global independent biopharmaceuticaldevelopment specialist in oncology and serious medical conditions,presented final results of two Debio 9902 (formerly ZT-1) studiesfor the treatment of
Alzheimer's disease (AD) at the Alzheime...
Medivation to Host Conference Call to Discuss Top-Line 12-Month
Results From Dimebon Alzheimer's Disease Study
SAN FRANCISCO, June 05, 2007 /PRNewswire-FirstCall/ --Medivation, Inc. today announced that it will hold a teleconferenceat 8:30 a.m. Eastern time on Monday, June 11, to discuss top-line12-month results from its randomized, double-blind,placebo-controlled Phase 2 clinical trial of Dimebon(TM), its leadproduct candidate, in
Alzheimer's disease. Rachelle Doody, M.D., Ph.D., lead inve...
Medivation Announces Presentation of New Subset Analyses From
Dimebon Phase 2 Alzheimer's Disease Trial at American Academy of
Neurology Annual Meeting
Company Conference Call Scheduled for Friday, May 4, at 9:00 a.m.Eastern Time to Discuss Data SAN FRANCISCO, May 03, 2007 /PRNewswire-FirstCall/ --Medivation, Inc. today announced that new data from the mild andmoderate subgroups of
Alzheimer's disease patients in the Company'ssix-month Phase 2 efficacy study of Dimebon showed that bothsubgroups were improved compared with placebo-treated...
Ceregene Presents Interim Phase 1 Clinical Data of CERE-110 for the
Treatment of Alzheimer's Disease
SAN DIEGO, Calif., May 02, 2007 /PRNewswire/ -- Ceregene, Inc.today presented interim clinical data from a Phase 1 trial ofCERE-110, a gene therapy product designed to deliver nerve growthfactor (NGF) for the treatment of
Alzheimer's disease. After oneyear of follow-up, the results for the six patients who receivedCERE-110 in the trial indicate that a single administration of thetherapy...
Samaritan Announces Positive Data in Nonclinical (IND) In-Vitro
Studies for Promising Alzheimer's Drug
Samaritan Announces Positive Data in Nonclinical (IND) In- VitroStudies for Promising
Alzheimer's Drug LAS VEGAS, May 3, 2007 (PRIME NEWSWIRE) -- SamaritanPharmaceuticals Inc. (AMEX:LIV), a developer of innovative drugs,is pleased to announce positive results were attained with itslate-stage preclinical/nonclinical testing of Caprospinol (SP-233),with well recognized in-vitro models....
Accera, Inc. Announces Results of Phase II Study in Alzheimer's
Disease at American Academy of Neurology Meeting
BROOMFIELD, Colo., May 01, 2007 /PRNewswire/ -- Accera Inc. ispresenting topline data today from its Phase IIb study of its leadcompound AC-1202 in
Alzheimer's disease (AD) at the AmericanAcademy of Neurology (AAN) 59th Annual Meeting in Boston. Judged bythe AAN to be in the top five percent of the program, the data willalso be featured in the Scientific Highlights Plenary Session. <p...
Cortex Area Thinner in Youth with Alzheimers-Related Gene
BETHESDA, Md., April 23, 2007--A part of the brain firstaffected by
Alzheimers disease (<a target="_blank" href="http://www.nia.nih.gov/
Alzheimers/">http://www.nia.nih.gov/
Alzheimers/ )is thinner in youth with a risk gene for the disorder, a brainimaging study by researchers at the National Institute of MentalHealth (NIMH), one of the National Institutes of Health (NIH), hasfound. A t...
Accera, Inc. to Present Results of Phase II Study in Alzheimer's
Disease at American Academy of Neurology Meeting
BROOMFIELD, Colo., April 24, 2007 /PRNewswire/ -- Accera Inc.announced today that topline data from its Phase IIb study of itslead compound AC-1202 in
Alzheimer's disease (AD) will be presentedat the annual meeting of the American Academy of Neurology (AAN) inBoston. Judged by the AAN to be in the top five percent of theprogram, the data will also be featured in the ScientificHighlights...
Medivation Announces First U.S. Presentation of Data From Dimebon
Phase 2 Alzheimer's Disease Trial at American Academy of Neurology
Annual Meeting
-- New Subset Analyses To Be Presented -- SAN FRANCISCO, April 24, 2007 /PRNewswire-FirstCall/ --Medivation, Inc. today announced that data from the Company's Phase2 efficacy study of Dimebon(TM) in
Alzheimer's disease will bepresented for the first time in the United States at the AmericanAcademy of Neurology's 59th Annual Meeting in Boston on Thursday,May 3, at 4:15 p.m. Eastern time. T...
Alzheimer's Drug Shows Promise in Fighting Cancer
LOS ANGELES, April 17, 2007 /PRNewswire/ -- Researchers from theBarbara Ann Karmanos Cancer Institute in Detroit, MI presentedstrong evidence today that an antibiotic typically prescribed for
Alzheimer's patients could be effective in eventually treatingcertain types of cancers. Q. Ping Dou, Ph.D., leader, Prevention Program at Karmanos, andmembers of his lab announced the findings...
Pharmathene's Recombinant Butyrylcholinesterase (rBChE) Program the
Subject of Promising New Alzheimer's Research
In Vitro Assays Show rBChE Suppresses Amyloid PlaqueFormation ANNAPOLIS, Md., April 3, 2007 - PharmAthene, Inc., a leadingbiodefense company specializing in the development andcommercialization of medical countermeasures against chemical andbiological terrorism, announced today that new data from itsrecombinant butyrylcholinesterase (rBChE) research program wererecently presented...
Allon Therapeutics to Present New Data at Leerink Swann Alzheimer's
Conference
VANCOUVER, British Columbia--(BUSINESS WIRE)--Apr 3, 2007 - AllonTherapeutics Inc. (TSX:NPC), The Neuro Protection Company(TM),announced today the publication of new preclinical data fromadditional confirmatory animal studies showing that Allon's productcandidate AL-108 significantly reduces the accumulation of amyloidpeptide and the hyperphosphorylation of tau protein in the brain,two path...
PharmAthene's Recombinant Butyrylcholinesterase (rBChE) Program the
Subject of Promising New Alzheimer's Research
In Vitro Assays Show rBChE Suppresses Amyloid Plaque Formation ANNAPOLIS, Md., April 03, 2007 /PRNewswire/ -- PharmAthene,Inc., a leading biodefense company specializing in the developmentand commercialization of medical countermeasures against chemicaland biological terrorism, announced today that new data from itsrecombinant butyrylcholinesterase (rBChE) research program wererecently pr...
Sarasota's Roskamp Institute Announces Positive Safety Data in
Human Clinical Study for Alzheimer's Disease
And Japanese Study Suggests the Drug Improves Memory SARASOTA, Fla., March 22, 2007 /PRNewswire-FirstCall/ -- TheRoskamp Institute announced today that it has received positivepreliminary results in its major clinical study that is testing apromising new drug application for the treatment of
Alzheimer'sdisease. The clinical study, which was first announced inSeptember, is the first human...
Alzheimer's Growth Shows Need for Increased FDA Funding
Coalition for a Stronger FDA says drug review programs need moremoney WASHINGTON, March 21, 2007 /PRNewswire-USNewswire/ -- A newestimate by the
Alzheimer's Association shows that more than fivemillion Americans are living with
Alzheimer's disease -- a 10percent growth over previous estimates and a number that could morethan triple in the coming decades unless new treatments and curesare...
Avid Announces Results of AV-1 Molecular Imaging Agent for
Alzheimer's Disease Presented at AD/PD Meeting
PHILADELPHIA--(BUSINESS WIRE)--Mar 19, 2007 - AvidRadiopharmaceuticals, Inc. (Avid), a product-focused molecularimaging company, today announced the presentation of the firstresults from a clinical study of 18F-AV-1/ZK (AV-1), a novelradiopharmaceutical for positron emission tomography (PET) imagingof amyloid plaques in patients with
Alzheimer's disease. Principalinvestigator Dr. Christophe...
Medivation Announces Presentation of Full Top-Line Data From
Dimebon Six-Month Trial at Major International Alzheimer's Disease
Conference
SAN FRANCISCO, March 19, 2007 /PRNewswire-FirstCall/ --Medivation, Inc. today announced that six-month results from itsrandomized, double-blinded, placebo-controlled Phase 2 efficacytrial of Dimebon(TM) in patients with mild-to-moderate
Alzheimer'sdisease demonstrated that patients treated with Dimebon weresignificantly improved compared to patients taking placebo on allfive efficacy end...